Italy Peptide Receptor Radionuclide Therapy (PRRT) Market – Insights

The market opportunities for key players to enter into this market are high owing to less competition and increasing demand for peptide receptor radionuclide therapy in the Italy market. Moreover, increasing incidence of cancer in Italy is directly contributing to demand for PRRT therapy. These factors are creating growth opportunities for companies to focus on research and development of new drugs. As per the Italian Association of Medical Oncology’s report, in April 2019, 71,000 new cases were diagnosed with new additional cancer cases.

The Italy Peptide Receptor Radionuclide Therapy (PRRT) Market was valued at US$ 3.6 million in 2019, and is expected to witness a CAGR of 9.2%over the forecast period (2019 – 2027).

Italy Peptide Receptor Radionuclide Therapy (PRRT) Market Share (%) Analysis, By Drug Type, 2019

Italy Peptide Receptor Radionuclide Therapy  | Coherent Market Insights

Source: Coherent Market Insights Analysis (2019)

Increasing incidence of pancreatic cancer, as well as availability of reimbursement for cancer drug is another factor contributing to the market growth.

Increasing incidence of pancreatic cancer in Europe region is expected to support growth of the market over the forecast period. For instance, according to United European Gastroenterology report in Europe region, there was a 5% increase in the number of pancreatic cancer cases during the years 1990 to 2016.

The European Medicines Agency (EMA) plays a central role in facilitating development and authorization of medicines for rare diseases, which are termed as ‘orphan medicines’. In Italy, prices of ODs (Orphan Drugs) and reimbursement by the National Health Service is set through negotiation between the Italian Medicines Agency (AIFA), and pharmaceutical companies. Reimbursement of 38% is available for ODs in Italy which includes peptide receptor radionuclide therapy (PRRT).

Italy Peptide Receptor Radionuclide Therapy (PRRT) Market - Restraints

High cost associated with cancer treatment, which include diagnosis and therapeutic treatment, is a major factor that is expected to restrain growth of the market. For instance, as per the Economist Intelligence Unit Limited’s 2016 report, lung cancer treatment cost has become a burden on the economy in Italy. In 2013, it was estimated that total cost for treatment of lung cancer reached around US$ 18.31 billion.

Currently, only one approved PRRT drug is available in the Italy market, and is used in the treatment of somatostatin receptor positive gastroenteropancreatic neuroendocrine tumor (GEP-NETs), including foregut, midgut, and hindgut neuroendocrine tumors in adults. Therefore, lack of availability of different drugs is another major factor restraining growth of the market.

Moreover, high cost of treatment is expected to restrain growth of the market. For instance, Novartis Company’s drug, Lutathera, is priced at US$ 99,900 for a full course of treatment comprising four infusions.

Italy Peptide Receptor Radionuclide Therapy (PRRT) Market Value (US$ Mn) & Y-o-Y Growth (%), 2016-2027

Italy Peptide Receptor Radionuclide Therapy  | Coherent Market Insights

 Source: Coherent Market Insights Analysis (2019)

Key player operating in the Italy Peptide Receptor Radionuclide Therapy (PRRT) Market is Novartis International AG.

Peptide receptor radionuclide therapy (PRRT) is a type of molecular therapy, also known as radioisotope therapy that is used for treating neuroendocrine tumors. In this therapy, a peptide similar to the natural hormone is combined with radioactive material such as Yttrium and Lutetium, to produce radionuclide which is then injected into the patient’s body. This combination binds to the neuroendocrine tumors in the body. It is a cell targeting type of therapy since it delivers a high dose of radiation directly to the tumor cells.

Market Dynamics

Rising number of cancer cases in Italy is expected to drive the Italy peptide receptor radionuclide therapy (PRRT) market growth during the forecast period. For instance, as per data published by the Epidemiology Unit, Agency for Health Protection of Milan, Corso Italia, in 2012- 2015, 3,803 patient  diagnosed with colorectal cancer. Cancer patients in the age group below 50 years accounted for 22.25%, of the total cancer cases that were reported and patients in the age group of 50 to 64 years accounted for 17.65%, and patients over the age of 65 accounted 20.80%.

Furthermore, according the WHO, in 2018, around 43,837 cases of prostate cancer were reported, which contributed around 10% of the total cancer cases recorded in Italy.

However, side effects associated with peptide receptor radionuclide therapy may negatively impact growth of the peptide receptor radionuclide therapy market. The side effects occur on the body part which is treated with radiation. Some of the common side effects faced by patients undergoing radiation therapy are nausea, vomiting, abdominal discomfort or pain, and in some cases, temporary hair loss and sub-acute hematology toxicity. Hence, this may hamper the Italy peptide receptor radionuclide therapy market growth.

Key features of the study:

  • This report provides in-depth analysis of the Italy peptide receptor radionuclide therapy (PRRT) market, market size (US$ Mn), and compound annual growth rate (CAGR (%) for the forecast period, 2019-2027, considering 2018 as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study provides key insights about market drivers, restraints, opportunities, new product launches or approvals, market trends, regional outlook, and competitive strategies adopted by leading players
  • It profiles the key player in the Italy peptide receptor radionuclide therapy (PRRT) market based on the following parameters: company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments, and strategies
  • The key player covered as a part of this study is Novartis International AG
  • Insights from this report would allow marketers and management authorities of companies to make informed decisions with respect to future product launches, governmental initiatives, technological up-gradation, market expansion, and marketing tactics
  • The Italy peptide receptor radionuclide therapy (PRRT) market report caters to various stakeholders in this industry, which include investors, product manufacturers, distributors, and suppliers for Italy Peptide Receptor Radionuclide Therapy (PRRT) Market, research and consulting firms, new entrants, and financial analysts

Detailed Segmentation:

  • Italy Peptide Receptor Radionuclide Therapy (PRRT) Market, by Drug Type:
    • Lutetium (Lu-177)-based
    • Yttrium (Y-90)-based
  • Italy Peptide Receptor Radionuclide Therapy (PRRT) Market, by Indication
    • Gastroenteropancreatic Neuroendocrine Tumor
  • Italy Peptide Receptor Radionuclide Therapy (PRRT) Market, by Distribution Channel:
    • Hospital Pharmacies
    • Retail Pharmacies
  • Company Profiles
    • Novartis International AG *
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Highlights
      • Strategies

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Drug Type
      • Market Snippet, By Indication
      • Market Snippet, By Distribution Channel
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Market Trends
    • Regulatory Scenario
    • Reimbursement Scenario
    • PEST Analysis
    • Key Developments
    • Epidemiology
  4. Italy Peptide Receptor Radionuclide Therapy (PRRT) Market, By Drug Type, 2019 – 2027, (US$ Million)
    • Introduction
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Lutetium (Lu-177)-based       
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027 , (US$ Million)
    • Yttrium (Y-90)-based
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027 , (US$ Million)
  5. Italy Peptide Receptor Radionuclide Therapy (PRRT) Market, By Indication, 2019 – 2027, (US$ Million)
    • Introduction
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Gastroenteropancreatic Neuroendocrine Tumor      
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027 , (US$ Million)
  6. Italy Peptide Receptor Radionuclide Therapy (PRRT) Market, By Distribution Channel, 2019 – 2027, (US$ Million)
    • Introduction
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Hospital Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027 , (US$ Million)
    • Retail Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027 , (US$ Million)
  7. Competitive Landscape
    • Company Profiles
      • Novartis International AG.*
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
  8. Section
    • References
    • Research Methodology         
    • About Us and Sales Contact

*Browse 9 market data tables and 12 figures on “Peptide Receptor Radionuclide Therapy (PRRT)” – Italy forecast to 2027”

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users