Treprostinil is a synthetic prostacyclin prescribed for the treatment of pulmonary arterial hypertension. Treprostinil works as a vasodilator lowering the blood pressure in the pulmonary artery leading from heart to lungs and is known to improve the ability to exercise. Treprostinil can be administered through oral route (orenitram), through inhaler (Tyvaso), and through infusion (Remodulin).

Global Treprostinil Drugs Market – Dynamics

A significant value is being generated every year by the companies that are involved in manufacturing and selling of treprostinil. For instance, in September 2018, United Therapeutics Corporation announced its financial results for the year 2018, where it stated that that global sales for Treprostinil were valued at around US$ 599 million in 2018.

Moreover, key players in the market are focusing on various strategies such as mergers, agreements, and acquisitions which is expected to propel the market growth. For instance, in September 2018, United Therapeutics entered into collaboration with MannKind Corporation for the development and commercialization of MannKind Corporation’s clinical-phase dry powder formulation of treprostinil. Mannkind Corporation is expected to generate more than US$ 95 million through this collaboration. Moreover, under the above mentioned agreement United Therapeutics will be responsible for global development, commercial, regulatory activities, and manufacturing supplies of treprostinil while the MannKind Corporation agreed to manufacture clinical as well as initial commercial supplies of the product.

Global Treprostinil Drugs Market – Regional Insights

North America accounted for the largest market share in 2018, owing to high presence of organizations involved in Treprostinil manufacturing and marketing business that have generated high revenue. For instance, in 2017, Remodulin (treprostilin injection) manufactured by the United Therapeautics, generated US$ 670.9 million, and 11.4% more than that in 2016 for the company.

Moreover, launches and approvals of various new treprostilin products are also likely to propel the market growth in the near future. For instance, in October 2019, the U.S. Food and Drug Administration (FDA) approved extended release treprostilin tablets, Orenitram, manufactured by United Therapeutics. The tablets are expected to delay to progression of pulmonary arterial hypertension disease. Similarly, in September 2019, United Therapeutics’ New Drug Application (NDA) received approved for review by the U.S. FDA for the product, Trevyent. Trevyent is a drug device combination product which contains PatchPump technology which enables treprostilin administration by subcutaneous route.

Global Treprostinil Drugs Market – Competitive landscape

Key players operating in treprostinil drugs market are United Therapeutics, Novartis, and Teva Pharmaceutical Industries Ltd. Players in the market are focused on developing new products, in order to enhance their market share. For instance, in March 2019, Sandoz, a division of Novartis, launched the Treprostinil Injection, a fully substitutable generic version of Remodulin Injection, in the market. Sandoz also confirmed that the firm has also gained the market exclusivity for the product for 180 days. Furthermore, in March 2019, Sandoz announced its plan to collaborate with RareGen, LLC for the commercialization of Treprostinil injection in order to boost product sales.

Global Treprostinil Drugs Market – Taxonomy

On the basis of dosage form, the global treprostinil drugs market is segmented into:

  • Injection
  • Inhalation
  • Tablets

On the basis of distribution channel, the global treprostinil drugs market is segmented into:

  • Hospital pharmacies
  • Retail pharmacies
  • Online pharmacies

On the basis of region, the global treprostinil drugs market is segmented into:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
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  • Distributors
  • End-users