Biotechnology

The biotech industry comprises bio-pharma, bio-services, bio-agri, bio-industrials and bioinformatics. Biopharma is a rapidly growing segment that accounts for a dominant share of this sector. Advancements in biotechnology has enabled researchers to evaluate and identify target biomarkers/cell receptors to develop targeted and personalized therapies. Increasing scientific understanding, advanced tools and techniques has led to emergence of various personalized medicines that are now in research phase. According to a research conducted by Personalized Medicine Coalition, 42% of all compounds and 73% of oncology compounds in the pipeline possess the potential to be personalized medicine. Moreover, according to this study, it is expected that companies will increase their investment in R&D of personalized medicines by 1/3rd over the following five years. The study found that over 20% of drugs approved in 2014 were personalized medicines.

Biotech sector has witnessed some disruptive innovations such as gene and cell therapies, immunotherapy, and antibody drug conjugates. Advancement in stem cell therapy is resulting in effective treatment therapies for chronic conditions, organ growth and repair and also in disease prevention.

Key Challenges

Biotech products have extensive usage in oncology and autoimmune disease treatments. However, the costs of these drugs are exorbitantly high owing to extensive research and trials that need to be carried out for the same. Therefore, there is constant pressure to reduce price and increase accessibility, especially in emerging economies. In the U.S., companies are facing reimbursement issues with respect to biopharmaceutical products. Besides, there are regulatory and scientific challenges faced by the sector. Scientific research for new molecules and targeted therapies is capital intensive and challenging, with increased concern for safety of the drug.

Also, there is lack of awareness about personalized medicine among most healthcare providers, which hinders its adoption. Clinical adoption of the biotech products is essential for its success. However, it entails a lot of scientific evidences and explanation to the prescribers in order to ensure its safety.

“Translating genomic discoveries into personalized medicines entails overcoming substantial scientific, regulatory, and economic challenges, including identifying validated biomarkers, as well as developing personalized therapeutics and clinically relevant diagnostic tests.”

  • Tufts Center for the Study of Drug Development

Opportunities

The biopharmaceutical sector offers vast lucrative growth opportunities. High efficacy and safety of biopharmaceutical products has led to increased demand for the same, with consumers willing to pay high prices for these as compared to other conventional products. Moreover, biopharmaceutical brands have set new standards for blockbuster drugs by recording an annual average sales of over US$ 2 Bn. Certain drugs such as Humira have generated sales of over US$ 10 Bn. Thus, investing in biotech R&D has yielded better results than pharmaceutical drugs.

For generic players, biosimilars offers a very good growth opportunity, as governments in emerging economies are supporting such therapies as cost-effective alternatives to biotech products. Therefore, cost-effectiveness and high quality are prime parameters that need to be considered while developing biosimilars. Recent and upcoming biologic patent expirations include the following:

  • Erbitux (cetuximab) - February 2016
  • Rituxan (rituximab) - September 2016
  • Herceptin (trastuzumab) - June 2019
  • Avastin (bevacizumab) - July 2019
  • Aranesp (darbepoetin alfa) - May 2024
  • Enbrel (etanercept) - November 2028

Companies such as Teva Pharmaceuticals, Hospira, Sandoz and Amgen are focusing their resources ondevelopment of biosimilars. Also, vaccines are other major products in development to focus on prevention aspect rather than just treatment. For instance, 2015 marked the U.S. launch of Zarxio TM, the first biosimilar approved in this market and the EMA approval of Mosquirix, the malaria vaccine. Extensive research is currently underway to develop a dengue vaccine, which could be another breakthrough pharmaceutical product in the near future.

Conclusion

Increasing research in biotech sector, in turn would translate into higher number of biopharma products seeking FDA approvals in future. Biopharma is positioned to be a promising treatment solution that would improve treatment outcomes and serve to accelerate and help reduce cost of drug development.

Insights are not available.
Coherent Market Insights
Automatic Cell Imaging System Market — Global Industry Insights, Trends, Size, Share, Outlook, and Opportunity Analysis, 2018–2026

To Be Published : Jul 2018

Live cell imaging, or cell imaging is the examination of living cells using time-lapse microscopy (time-lapse photography applied to microscopy). Cell Imaging is used by scientists to get a better understanding of the biological functions of the body in the course of

Coherent Market Insights
Bone Marrow Transplant Market – Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016–2024

To Be Published : Jul 2018

Bone marrow transplant is a medical procedure to replace bone marrow damaged or destroyed by disease, infection, or chemotherapy. Bone marrow transplant procedure involves transplanting blood stem cells that travel to the bone marrow where they produce new blood cells

Coherent Market Insights
Nanoemulsion Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016–2024

To Be Published : Jul 2018

Nanoemulsion is the process of suspension of minimicrons of globules of one liquid to other liquids that are immiscible to each other. Nanoemulsions are oil-in-water emulsions with mean size ranging from 50 to 1000 nm. Average size of a droplet is between 100 and 500

Coherent Market Insights
Ubiquitin Enzymes Market — Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016–2024

To Be Published : Jul 2018

Ubiquitin enzymes, is also termed by E2 enzyme and seldom as known ubiquitin-carrier enzymes. This helps to achieve the second successive step in the ubiquitination process that aims at a protein to cut into various segments through the proteasome. The ubiquitination

Coherent Market Insights
Graft Versus Host Disease (GvHD) Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016-2024

To Be Published : Jul 2018

During any transplant of stem cell and bone marrow some complications arises that may be mild or severe, those are the graft versus host disease (Gvhd) they occur especially in immune-compromised patients. During cancer treatment, the radioactive agents or the chemica

Coherent Market Insights
Human Microbiome Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016–2024

To Be Published : Jul 2018

Microbial cells outnumber the human cells in the ratio 10:1 in a health human body. Human microbiome is the study of microbes present in the human body. These are beneficial microbes that carry out functions not performed by any gene in the human DNA and hence, they p

Coherent Market Insights
Antibody Drug Conjugates Market — Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016–2024

To Be Published : Jul 2018

Antibody drug conjugate is a significant class of highly potent bio drugs envisioned as a broad therapy for treatment of cancer. Unlike chemotherapy, antibody drug conjugate are proposed to mark and kill only cancer cells. Antibody drug conjugates are compound molecul

Coherent Market Insights
Natural Killer Cells Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016–2024

To Be Published : Jul 2018

Natural killer cells are a form of granular lymphocytes of varying sizes that play an important role in innate immunity in the human body. They typically constitute of around 10% of total blood lymphocytes as compared to around 70% and 20% of T cells and B cells, resp

Coherent Market Insights
Sterility Testing Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016-2024

To Be Published : Jul 2018

Sterility testing in pharmaceutical manufacturing is a vital process during the sterilization and validation process along with release testing. It is an essential part of every sterilization validation process in several industries that makes it a vital procedure in

Coherent Market Insights
Phosphodiesterase Enzyme (PDE) Inhibitors Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018–2026

To Be Published : Jul 2018

Phosphodiesterase are a diverse family of enzymes (11 isoenzymes) that play a key role in regulating intracellular levels of secondary messengers - cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate. These enzymes identified to be pharmacological

Coherent Market Insights
Digital Genome Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016–2024

To Be Published : Jul 2018

Digital Genome Market Overview Digital genome is the complete digital set of genes or genetic material present in a cell or organism. Genome is the branch of biology that deals with the study of genes and their fun

Coherent Market Insights
Synthetic Biology Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016-2024

To Be Published : Jul 2018

Synthetic biology is a combination of biology and biomedical engineering principles that favors designing and construction of novel biological parts & systems and also the reconstruction of preexisting designs according to specific application requirements. Synthe

Coherent Market Insights
Radial Head Resection Implants Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018–2026

To Be Published : Jul 2018

Elbow is a complex joint and a crucial part for forearm function. It has a unique anatomy comprising limited ball-and-socket joint and a hinge type of synovial joint, which allows for hand movement and control. Though radial head fractures are usually not too complica

Coherent Market Insights
Regenerative Artificial Skin Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016-2024

To Be Published : Jul 2018

Incidence of accidental skin burns are increasing across the globe. Life threatening skin injuries, traumas, and burns require immediate surgical procedure to restore skin and avoid future complications. Skin burns are broadly classified into three levels, namely 1st,

Coherent Market Insights
Psoriasis Treatment Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018–2026

To Be Published : Jul 2018

Psoriasis is a non-communicable autoimmune disease characterized by patches of abnormal skin. These skin spots are red, itchy, and scaly which may be small and localized or cover the entire body. Skin injury may cause psoriatic skin changes at

Coherent Market Insights
Plant Stem Cell Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016–2024

To Be Published : Jul 2018

Plant Stem Cell Market Overview Plant stem cells are undifferentiated cells within the meristems of plants. Plant stem cells serve as the origin of plant vitality as they maintain themselves and provide a steady supply of precursor cells to form v

Coherent Market Insights
Tissue Transplantation Products and Services Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016-2024

To Be Published : Jul 2018

Chronic diseases often lead to catastrophic damage to vital organs. This damage is usually irreversible and leads to lifetime dependency on medicines. Under such severe conditions, transplants remain the mainstay for restoration of healthy life. Globally, there has be

Coherent Market Insights
Subcutaneous Biologics Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2016-2024

To Be Published : Jul 2018

Biologic, also known as biopharmaceutical, is a complex medicinal product manufactured by a biological process. Examples of biologics include blood and plasma derived products, vaccines, somatic cells and body proteins. Biologics market refers to a multibillion dollar

"How Can I Help You" ?

Finding it difficult to find the research that would cater to your business demands? Give us a chance to help you. One of our Research Consultants will connect to provide a customized solution.

Coherent Market Insights Benefits

  • Custom Research Solution

    Talk to our research consultant to design an exclusive report as per your research needs.

  • Customer Fulfilment

    We aim to fulfil client's research demands with tailored research solutions.

  • Quick Turnaround Time Reports

    We aim to provide research studies in quickest turnaround time and in a much cost effective manner.

  • 360-degree Approach

    We cover each industry from supply and demand side with an aim to provide a most holistic research study.

  • Assured Quality

    We strive to provide most accurate and reliable research findings in our research reports.