Two therapies are used for treatment of ITP in Middle East, and it is categorized into first-line therapy (Corticosteroids, intravenous immunoglobulin (IVIG), and anti-D immune globulin) and second-line therapy (thrombopoietin receptor agonists, monoclonal antibody). However, despite availability of these therapies, some patients still remain refractory to the treatment.
The ongoing research for treatment of ITP is focused on combining therapies and addressing multiple mechanisms of the disease simultaneously. As per data published by the American Society of Hematology in July 2018, the emerging combination therapies for ITP treatment are the combination of drugs, dexamethasone and rituximab which has been examined in several trials and has been indicated to provide superior results to either drug as monotherapy in some patients, and the possibility to revert lymphocyte subset abnormalities commonly seen in active disease. The addition of cyclosporine to rituximab and dexamethasone has also been evaluated in small adult studies and has provided enduring remission in a subset of treated patients, without substantial reported toxicity.
Market Dynamics
Increasing prevalence of immune thrombocytopenic purpura in pediatric population is expected to drive growth of the immune thrombocytopenic purpura drugs market in Middle East and Turkey. For instance, according to data published by the Paediatric Blood Cancer journal in 2013, around 10% of children with acute immune thrombocytopenia purpura were admitted to hospitals in Egypt in 2013.
The immune thrombocytopenic purpura drugs market growth in the Middle East and Turkey is expected to be hampered, owing to slower execution of rules and regulations regarding the approval and launch of treatment drugs compared to North America and Europe. For instance, in the Middle East, Amgen Inc.'s Nplate (romiplostim) is the only drug currently available for treatment of immune (idiopathic) thrombocytopenic purpura (ITP). This drug is present in the U.S. since 2003. Later in 2006, Amgen launched it in Israel, Kuwait, Egypt, and Lebanon.
Key features of the study
Market Segmentation
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