Recombinant Human EGF (Epidermal Growth Factor) is a peptide that binds to the membrane receptor called EGF receptor in humans to promote cell proliferation and cell differentiation. EGF acts by initiating number of cell signaling cascade pathways such as activating genes for cell proliferation, cell differentiation, protein synthesis, and improving efficiency of DNA topoisomerase. Traditionally, EGF was isolated from animal urine but with recent advances in biotechnology, the production and extraction of recombinant EGF have become possible in a lab setting. Recombinant EGF can be produced using various biological systems such as Escherichia coli, tobacco, rice, yeast, and others. EGF can be used for several applications in the field of medicine, research, cell culture, cosmetology, and others. EGF exhibits medically important properties such as initiation of growth and division in cells that can be exploited for clinical application of wound healing as well as for the treatment of ulcers. For instance, according to an article published by the American Institute of Physics in June 2020, high levels of recombinant human EGF (rhEGF) were obtained by co-expression of human EGF (hEGF) in Escherichia coli with Bacillus cereus phospholipase C. This rhEGF can then be used for the treatment of diabetic foot ulcers along with other wound treatments.
Market Dynamics
Market players are conducting clinical trials for analyzing the potential uses of human EGF in healthcare sector, this could contribute to the growth of the market over the forecast period. For instance, a clinical trial study was initiated in July 2017 by Hallym University Kangnam Sacred Heart Hospital, Korea, for determining the effectiveness of recombinant human EGF ointment in healing lesions caused by laser treatment for solar lentigines. The study was completed in December 2018 and the results were published by PubMed in February 2021. Results showed that the use of recombinant human EGF ointment was safe and efficient for healing lesions.
Market players are involved in acquisitions of other companies in order to enhance distribution. For instance, in 2018, FUJIFILM, a Japanese multinational conglomerate, acquired Irvine Scientific Sales Company, Inc., a cell media specialist, to expand its range of cell culture media products including recombinant human EGF. This is expected to drive the growth of the recombinant human EGF market.
Key features of the study
Market Segmentation
Market Segmentation
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