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Prothrombin Complex Concentrates Market, By Type (3-Factor PCC, 4-Factor PCC), By Application (Acquired Coagulation Factor Deficiency, Congenital Coagulation Factor Deficiency, Others), By End User (Hospital, Ambulatory Surgical Centres, Others), By Geography (North America, Latin America, Europe, Asia Pacific, Middle East & Africa)

  • Published In : 24 Jun, 2026
  • Code : CMI4647
  • Pages :254
  • Formats :
      Excel and PDF
  • Industry : Pharmaceutical
  • 역사적 분포 범위 : 2020 - 2024
  • 기준 연도 : 2025
  • 예상 연도 : 2026
  • 예측 기간 : 2026- 2033

Prothrombin complex concentrates (PCCs) are highly purified concentrate prepared from blood plasma with hemostatic activity contain four vitamin K-dependent clotting factors (F) (II (prothrombin), VII, IX and X), for replacement therapy in patients with congenital or acquired deficiencies.

Moreover, in several European countries, prothrombin complex concentrates are also used in the management of massive peri- and postoperative bleeding.

Market Dynamics

Global Prothrombin Complex Concentrates Market is expected to show significant growth, owing to increasing approval of product. For instance, in 2013, the U.S Food and Drug Administration (FDA) accepted Octapharma USA’s Biological License Application (BLA) for octaplex 4-Factor PCC, for indication of reversal of anticoagulation therapy in patients undergoing vitamin K antagonist therapy with the need for urgent surgery or invasive procedures

Key features of the study

  • This report provides in-depth analysis of the global prothrombin complex concentrates market, provides market size (US$ Mn) and compound annual growth rate (CAGR%) for the forecast period (2026–2033), considering 2025 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends,  regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the global prothrombin complex concentrates market based on the following parameters – company highlights, products portfolio, key highlights, financial performance, and strategies
  • Key companies covered as a part of this study include Octapharma AG, Nihon Pharmaceutical Co Ltd, Grifols S.A., CSL Behring GmbH, Kedrion Biopharma Inc., Shire Plc, China Biologic Products Holdings, Inc., and Sanquin
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
  • The global prothrombin complex concentrates market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global prothrombin complex concentrates market

Market Segmentation

  • By Type (Revenue, USD Mn, 2021-2033)
    • 3-Factor PCC
    • 4-Factor PCC
  • By Application (Revenue, USD Mn, 2021-2033)
    • Acquired Coagulation Factor Deficiency
    • Congenital Coagulation Factor Deficiency
    • Others
  • By End User (Revenue, USD Mn, 2021-2033)
    • Hospital
    • Ambulatory Surgical Centres
    • Others
  • By Region (Revenue, USD Mn, 2021-2033)
    • North America
      • U.S.
      • Canada
    • Latin America
      • Brazil
      • Mexico
      • Argentina
      • Rest of Latin America
    • Europe
      • Germany
      • U.K.
      • France
      • Italy
      • Spain
      • Russia
      • Rest of Europe
    • Asia Pacific
      • China
      • India
      • Japan
      • Australia
      • South Korea
      • ASEAN
      • Rest of Asia Pacific
    • Middle East
      • GCC
      • Israel
      • Rest of Middle East
    •  Africa
      • South Africa
      • Central Africa
      • North Africa
  • Key Players
    • Octapharma AG
    • Nihon Pharmaceutical Co. Ltd.
    • Grifols S.A.
    • CSL Behring GmbH
    • Kedrion Biopharma Inc.
    • Shire Plc
    • China Biologic Products Holdings, Inc.
    • Sanquin

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snapshot, By Type
      • Market Snapshot, By Application
      • Market Snapshot, By End User
      • Market Snapshot, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Market Trends
    • Key Developments
    • Product Approval
    • Collaboration/Merge/Acquisition
    • Regulatory Landscape
    • PEST Analysis
    • Porter’s Five Forces Analysis
    • Epidemiology
    • Robust Pipeline Analysis
  4. Global Prothrombin Complex Concentrates Market, By Type, 2021 – 2033, (USD Mn)
    • Introduction
      • Market Share Analysis, 2026 and 2033 (%)
      • Y-o-Y Growth Analysis, 2022– 2033
      • Segment Trends
    • 3-Factor PCC
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2021–2033, (USD Mn)
    • 4-Factor PCC
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2021–2033, (USD Mn)
  5. Global Prothrombin Complex Concentrates Market, By Application, 2021 – 2033, (USD Mn)
    • Introduction
      • Market Share Analysis, 2026 and 2033 (%)
      • Y-o-Y Growth Analysis, 2022 – 2033
      • Segment Trends
    • Acquired Coagulation Factor Deficiency
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2021–2033, (USD Mn)
    • Congenital Coagulation Factor Deficiency
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2021–2033, (USD Mn)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2021–2033, (USD Mn)
  6. Global Prothrombin Complex Concentrates Market, By End User, 2021 – 2033, (USD Mn)
    • Introduction
      • Market Share Analysis, 2026 and 2033 (%)
      • Y-o-Y Growth Analysis, 2022 – 2033
      • Segment Trends
    • Hospital
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2021–2033, (USD Mn)
    • Ambulatory Surgical Centres
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2021–2033, (USD Mn)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2021–2033, (USD Mn)
  7. Global Prothrombin Complex Concentrates Market, By Region, 2021 – 2033, (USD Mn)
    • Introduction
      • Market Share Analysis, By Region, 2026 and 2033 (%)
      • Y-o-Y Growth Analysis, For Regions, 2022–2033
      • Regional Trends
    • North America
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2021 – 2033, (USD Mn)
        • U.S.
        • Canada
    • Latin America
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2021 – 2033, (USD Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2021 – 2033, (USD Mn)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2021 – 2033, (USD Mn)
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Middle East
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2021 – 2033, (USD Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Application, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2021 - 2033, (USD Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Country, 2021 – 2033, (USD Mn)
        • North Africa
        • Central Africa
        • South Africa
  8. Competitive Landscape
    • Heat Map Analysis
    • Market Share Analysis
    • Company Profile
      • Octapharma AG
        • Company Highlights
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Market Strategies
      • Nihon Pharmaceutical Co. Ltd.
        • Company Highlights
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Market Strategies
      • Grifols S.A.
        • Company Highlights
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Market Strategies
      • CSL Behring GmbH
        • Company Highlights
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Market Strategies
      • Kedrion Biopharma Inc.
        • Company Highlights
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Market Strategies
      • Shire Plc
        • Company Highlights
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Market Strategies
      • China Biologic Products Holdings, Inc.
        • Company Highlights
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Market Strategies
      • Sanquin
        • Company Highlights
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Market Strategies
    • Analyst Views
  9. Section
    • References
    • Research Methodology
    • About Us
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