Mtor inhibitors market

mTOR Inhibitors Market, by Drug Type (Everomilus, Temsirolimus, Siromilus), By Indication (Oncology, Immunosuppressant, Organ Transplant, Others), by Route of Administration (Oral, Intravenous), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Outlook, and Opportunity Analysis, 2022 - 2030

  • May 2022
  • CMI5019
  • 175 Pages
  • Excel & Pdf
  • Pharmaceutical

Mechanistic target of rapamycin (mTOR) is a protein kinase regulating cell growth, survival, metabolism, and immunity. Inhibitors of the mammalian target of rapamycin are a new class of immunosuppressants. There are three commercially available mammalian (mechanistic) target of rapamycin (mTOR) inhibitors approved by the U.S. Food and Drug Administration (FDA) approved: sirolimus, everolimus, and temsirolimus. Mammalian target of rapamycin (mTOR) inhibitors are used in the treatment of renal cancer and is being studied for use in other types of cancers. Mechanistic target of rapamycin (mTOR) inhibitors provides more benefits when used with chemotherapy agents to treat cancers.

Global mTOR Inhibitors Market - Impact of the Coronavirus (COVID-19) Pandemic

The COVID-19 pandemic has negatively impacted the growth of global mTOR inhibitors market. The COVID-19 pandemic affected the health care systems globally and resulted in the interruption of usual care in many health care facilities, exposing vulnerable patients with cancer to significant risks. Our study aimed to evaluate the impact of this pandemic on cancer care worldwide. According to an article published by American Society of Clinical Oncology, in September 2020, a survey was conducted by An American Society of Clinical Oncology Journal, total of 356 centers from 54 countries across six continents participated between April 21 and May 8, 2020. These centers serve 716,979 new patients with cancer a year. Most of them (88.2%) reported facing challenges in delivering care during the pandemic. Although 55.34% reduced services as part of a preemptive strategy, other common reasons included an overwhelmed system (19.94%), lack of personal protective equipment (19.10%), staff shortage (17.98%), and restricted access to medications (9.83%).  Participants reported patient exposure to harm from interruption of cancer-specific care (36.52%) and non-cancer-related care (39.04%), with some centers estimating that up to 80% of their patients were exposed to harm. Thus, the COVID-19 has negatively impacted the global mTOR inhibitors market.

Global mTOR inhibitors market is estimated to be valued at US$ 6,704.5 thousand in 2022 and expected to exhibit a CAGR of 4.5% over the forecast period (2022-2030).

Figure 1: Global mTOR Inhibitors Market Share (%) Analysis, By Drug Type, 2022

 

The increasing number of generic drug launches by the market players is expected to drive the growth of global mTOR inhibitors market over the forecast period.

Market players are focused on organic growth strategies such as drug launches, which is expected to drive the market growth over the forecast period. For instance, in February 2018, Biocon Ltd., a biopharmaceutical company announced the launch of Everolimus tablets, a generic version of Afinitor, in the U.S. Everolimus tablets will be introduced in 2.5mg, 5mg, 7.5mg and 10mg strengths.

mTOR Inhibitors Market Report Coverage

Report Coverage Details
Base Year: 2019 Market Size in 2022: US$ 6,704.5 Mn
Historical Data for: 2016 to 2019 Forecast Period: 2022 to 2030
Forecast Period 2020 to 2027 CAGR: 4.5% 2030 Value Projection: US$ 9,534.5 Mn
Geographies covered:
  • Region: North America, Latin America, Europe, Asia Pacific, Middle East, Africa
Segments covered:
  • By Drug Type: Everolimus, Temsirolimus, Sirolimus
  • By Indication: Oncology, Immunosuppressant, Organ Transplantation, Others
  • By Route of Administration: Oral, Intravenous
  • By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
Companies covered:

Novartis AG, Hikma Pharmaceuticals PLC., Par Pharmaceutical, Teva Pharmaceutical Industries Ltd., Dr. Reddy’s Laboratories Ltd., Zydus Cadilla, Pfizer, Inc., Biocon, Alkem Laboratories Ltd., Accord Healthcare Inc., Gland Pharma Ltd., Apotex Inc., and Glenmark Pharmaceuticals Ltd.

Growth Drivers:
  • The increasing number of generic drug launches
  • Increasing number of product approvals from regulatory bodies.
Restraints & Challenges:
  • High price of drugs

The increasing number of product approvals from regulatory bodies is expected to drive the growth of global mTOR inhibitors market over the forecast period.

Market players are focused on gaining product approvals from regulatory bodies, which is expected to drive the growth of global mTOR inhibitors market over the forecast period. For instance, in October 2020, Glenmark Pharmaceuticals, a pharmaceutical company, announced that the U.S. Food and Drug Administration has approved generic version of Rapamune tablets, 0.5mg, 1mg and 2mg. The drug is the generic version of Pfizer, Inc. and Wyeth Pharmaceuticals, a pharmaceutical company’s Rapamune tablets.   

Global mTOR Inhibitors Market – Restraints

The high price of drugs (including branded and generic) is a major hurdle for the market growth. For instance, according to Drugs. Com., the price of Temsirolimus intravenous solution (25mg/mL), indicated for the treatment of advanced renal cell carcinoma is around US$ 1,213.

Global mTOR Inhibitors Market – Region Analysis

On the basis of region, global mTOR inhibitors market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East and Africa.

North America is expected to hold a dominant position in the market during the forecast period, owing to increasing number of product approvals from regulatory bodies in the region. For instance, in February 2016, Novartis AG, a pharmaceutical company, announced that the U.S.Food and Drug Administration (FDA) approved Afinitor (everolimus) tablets for the treatment of adult patients with progressive, well-differentiated, nonfunctional neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin that are unresectable, locally advanced or metastatic.

Figure 2: Global mTOR Inhibitors Market (US$ Mn), by Country, 2022

Global mTOR Inhibitors Market – Competitive Landscape

Major players operating in global mTOR inhibitors market include Novartis AG, Hikma Pharmaceuticals PLC., Par Pharmaceutical, Teva Pharmaceutical Industries Ltd., Dr. Reddy’s Laboratories Ltd., Zydus Cadilla, Pfizer, Inc., Biocon, Alkem Laboratories Ltd., Accord Healthcare Inc., Gland Pharma Ltd., Apotex Inc., and Glenmark Pharmaceuticals Ltd. 

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Drug Type
      • Market Snippet, By Indication
      • Market Snippet, By Route of Administration
      • Market Snippet, By Distribution Channel
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Key Development
    • PEST Analysis
    • Regulatory Scenario
    • Pipeline Analysis
    • New Product Launch/ Approval
    • Epidemiology
    • Market Trends
  4. Global mTOR Inhibitors Market - Impact of Coronavirus (Covid-19) Pandemic
    • Economic Impact
    • COVID-19 Epidemiology
    • Government Initiatives to Combat COVID-19
  5. Global mTOR Inhibitors Market, By Drug Type, 2017-2030 (US$ Million)
    • Introduction
      • Market Share Analysis, 2022 and 2030 (%)
      • Y-o-Y Growth Analysis, 2018 - 2030
      • Segment Trends
    • Everolimus
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030, (US$ Million)
    • Temsirolimus
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030, (US$ Million)
    • Sirolimus
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030, (US$ Million)
  6. Global mTOR Inhibitors Market, By Indication, 2017-2030 (US$ Million)
    • Introduction
      • Market Share Analysis, 2022 and 2030 (%)
      • Y-o-Y Growth Analysis, 2018 - 2030
      • Segment Trends
    • Oncology
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030, (US$ Million)
    • Immunosuppressant
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030, (US$ Million)
    • Organ Transplantation
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030, (US$ Million)
  7. Global mTOR Inhibitors Market, By Route of Administration, 2017-2030 (US$ Million)
    • Introduction
      • Market Share Analysis, 2022 and 2030 (%)
      • Y-o-Y Growth Analysis, 2018 - 2030
      • Segment Trends
    • Oral
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030, (US$ Million)
    • Intravenous
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030, (US$ Million)
  8. Global mTOR Inhibitors Market, By Distribution Channel, 2017 - 2030 (US$ Million)
    • Introduction
      • Market Share Analysis, 2022 and 2030 (%)
      • Y-o-Y Growth Analysis, 2018 - 2030
      • Segment Trends
    • Hospital Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2018 - 2030, (US$ Million)
    • Retail Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030, (US$ Million)
    • Online Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2030 (US$ Million)
  9. Global mTOR Inhibitors Market, By Region, 2017 - 2028 (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2022 and 2030 (%)
      • Y-o-Y Growth Analysis, For Regions, 2018 - 2030
      • Regional Trends
    • North America
      • Market Size and Forecast, By Drug, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Indication, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Country, 2017 - 2030 (US$ Mn)
        • U.S.
        • Canada
    • Latin America
      • Market Size and Forecast, By Drug, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Indication, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Country, 2017 - 2030 (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Market Size and Forecast, By Drug, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Indication, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Country, 2017 - 2030 (US$ Mn)
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Drug, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Indication, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Country, 2017 - 2030 (US$ Mn)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • Market Size and Forecast, By Drug, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Indication, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Country, 2017 - 2030 (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Market Size and Forecast, By Drug, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Indication, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2017 - 2030 (US$ Mn)
      • Market Size and Forecast, By Country/Region, 2017 - 2030 (US$ Mn)
        • South Africa
        • Central Africa
        • North Africa
  10. Competitive Landscape
    • Company Profiles
      • Novartis AG
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Hikma Pharmaceuticals PLC.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Par Pharmaceutical
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Teva Pharmaceutical Industries Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Reddy’s Laboratories Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Zydus Cadilla
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Pfizer, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Biocon
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Alkem Laboratories Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Accord Healthcare Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Gland Pharma Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Apotex Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
      • Glenmark Pharmaceuticals Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
        • Strategies
    • Analyst Views
  11. Section
    • References
    • Research Methodology
    • About Us and Sales Contact

*Browse 39 market data tables and 22 figures on "Global mTOR Inhibitors Market” - Forecast to 2030

Detailed Segmentation:

  • Global mTOR Inhibitors Market, By Drug Type:
    • Everolimus
    • Temsirolimus
    • Sirolimus
  • Global mTOR Inhibitors Market, By Indication:
    • Oncology
    • Immunosuppressant
    • Organ Transplantation
    • Others
  • Global mTOR Inhibitors Market, By Route of Administration:
    • Oral
    • Intravenous
  • Global mTOR Inhibitors Market, By Distribution Channel:
    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies
  • Global mTOR Inhibitors Market, By Region:
    • North America
      • By Drug Type:
        • Everolimus
        • Temsirolimus
        • Sirolimus
      • By Indication:
        • Oncology
        • Immunosuppressant
        • Organ Transplantation
        • Others
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • U.S.
        • Canada
    • Latin America
      • By Drug Type:
        • Everolimus
        • Temsirolimus
        • Sirolimus
      • By Indication:
        • Oncology
        • Immunosuppressant
        • Organ Transplantation
        • Others
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Drug Type:
        • Everolimus
        • Temsirolimus
        • Sirolimus
      • By Indication:
        • Oncology
        • Immunosuppressant
        • Organ Transplantation
        • Others
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Drug Type:
        • Everolimus
        • Temsirolimus
        • Sirolimus
      • By Indication:
        • Oncology
        • Immunosuppressant
        • Organ Transplantation
        • Others
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • Australia
        • India
        • China
        • Japan
        • ASEAN
        • South Korea
        • Rest of Asia Pacific
    • Middle East
      • By Drug Type:
        • Everolimus
        • Temsirolimus
        • Sirolimus
      • By Indication:
        • Oncology
        • Immunosuppressant
        • Organ Transplantation
        • Others
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Drug Type:
        • Everolimus
        • Temsirolimus
        • Sirolimus
      • By Indication:
        • Oncology
        • Immunosuppressant
        • Organ Transplantation
        • Others
      • By Route of Administration:
        • Oral
        • Intravenous
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country/Region:
        • South Africa
        • Central Africa
        • North Africa
- Frequently Asked Questions -

What will be the compound annual growth rate (CAGR) of Global mTOR Inhibitors Market during the forecast period (2022-2030)?

Global mTOR inhibitors market is expected to exhibit a CAGR of 4.5% during the forecast period (2022-2030).

What is the estimated market size of the market in 2022?

The market is estimated to be valued at US$ 6,704.5 Mn in 2022.

Which are the prominent players operating in the market?

Novartis AG, Hikma Pharmaceuticals PLC., Par Pharmaceutical, Teva Pharmaceutical Industries Ltd., Dr. Reddy’s Laboratories Ltd., Zydus Cadilla, Pfizer, Inc., Biocon, Alkem Laboratories Ltd., Accord Healthcare Inc., Gland Pharma Ltd., Apotex Inc., and Glenmark Pharmaceuticals Ltd. are some of the prominent players operating in the market.

What are the growth estimates for the market till 2030?

The market is expected to be valued at US$ 9,534.5 Mn in 2030.

Which are the prominent region in the market?

North America is the prominent region in the market

Which is the prominent segment in the market?

Everolimus, which belongs to the drug type segment, is the prominent segment in the market
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