Macrophages are white blood cells that play a key role in immunity and homeostasis. They act as first responders, ingesting foreign materials, microbes, and debris. Due to their importance, it is essential to characterize and study macrophage biology. Macrophage markers allow researchers to identify, isolate, track, and target these cells. There are two main types of macrophage markers. The first are cell surface markers, which are proteins expressed on the outer membrane of macrophages that can be detected using fluorescence-activated cell sorting or immunohistochemistry techniques. Common macrophage cell surface markers include CD68, CD14, CD163, and CD206. The second type are intracellular markers, which are proteins located inside macrophage cells.
Intracellular markers provide information about macrophage activation and function but require fixed and permeabilized cells. Cell surface markers have the advantage of allowing live cell analysis, isolation, and potentially targeting of macrophages. However, no single marker is specific enough to uniquely identify macrophages, and marker expression can change depending on activation state and tissue environment. Ideally, a combination of several markers is used to accurately characterize macrophage phenotypes and populations. The global market offers a wide variety of monoclonal antibodies against macrophage markers, aiding fundamental and applied research seeking new treatment strategies across medical conditions.
Market Dynamics
- Increasing research in immunology, the growing prevalence of chronic diseases, technological advancements, and personalized medicine approaches are major factors expected to drive growth of the global macrophage marker market during the forecast period.
- For instance, in June 2022, according to a report published by the National Center for Biotechnology information, approximately 21% of the elderly in India reportedly have at least one chronic disease.
- While, in December 2020, according to a report published by the Union for International Cancer Control, globally, 1 in 5 people develop cancer during their lifetime, and 1 in 8 men and 1 in 11 women die from the disease.
- However, the complexity of macrophage heterogeneity, a lack of specificity and sensitivity, and the limited availability of validated antibodies are expected to hamper growth of the global macrophage marker market over the forecast period.
Key features of the study:
- This report provides in-depth analysis of the global macrophage marker market, and provides market size (US$ Mn) and compound annual growth rate (CAGR%) for the forecast period (2023–2030), considering 2022 as the base year
- It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
- This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
- It profiles key players in the global macrophage marker market based on the following parameters – company highlights, products portfolio, key highlights, financial performance, and strategies
- Key companies covered as a part of this study include Abcam plc, Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., BD Biosciences, Thermo Fisher Scientific, Inc., Agilent Technologies, Inc., BioLegend, Inc., Merck KGaA, Novus Biologicals, LLC, R&D Systems, Inc. (a Bio-Techne brand), Santa Cruz Biotechnology, Inc., Beckman Coulter, Inc., Miltenyi Biotec GmbH, GeneTex, Inc., MBL International Corporation.
- Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
- The global macrophage marker market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
- Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global macrophage marker market
Macrophage Marker Market Detailed Segmentation:
- By Marker Type:
- CD68
- CD163
- CD206
- CD14
- CD11b
- CD64
- CD11c
- Others
- By Application:
- Research Use
- Diagnostic Use
- Drug Development
- By Disease Area:
- Oncology
- Infectious Diseases
- Autoimmune Diseases
- Cardiovascular Diseases
- Neurological Disorders
- Others
- By End User:
- Research Institutes and Academic Centers
- Pharmaceutical and Biotechnology Companies
- Clinical and Diagnostic Laboratories
- Others
- By Region:
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East
- Africa
- Top companies in Global Macrophage Marker Market
- Abcam plc
- Bio-Rad Laboratories, Inc.
- Cell Signaling Technology, Inc.
- BD Biosciences
- Thermo Fisher Scientific, Inc.
- Agilent Technologies, Inc.
- BioLegend, Inc.
- Merck KGaA
- Novus Biologicals, LLC
- R&D Systems, Inc. (a Bio-Techne brand)
- Santa Cruz Biotechnology, Inc.
- Beckman Coulter, Inc.
- Miltenyi Biotec GmbH
- GeneTex, Inc.
- MBL International Corporation
