Biliary atresia treatment market

Biliary Atresia Treatment Market, by Disease Type (Type I, Type II, and Type III), by Treatment Type (Medications (Bile Acids, Antibiotics, and Corticosteroids) and Surgery), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Outlook, and Opportunity Analysis, 2021 - 2028

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Nov 2021
CMI4779
191 Pages
Excel & Pdf
Pharmaceutical

Summary

Biliary atresia is a rare condition which majorly occurs in infants. In this condition, the bile ducts that transport bile from the liver to the gall bladder are blocked. The symptoms of this disease appear about two to eight weeks after birth. Symptoms of the biliary atresia include jaundice, pale colored stools, slow or no weight gain, dark urine, and an enlarged spleen. Once biliary atresia is suspected, a surgery called Kasai portoenterostomy needs to be performed, as early operation is more likely to be successful. If the Kasai operation fails, liver transplantation may be needed.

The global biliary atresia treatment market is estimated to be valued at US$ 910.7 million in 2021 and is expected to exhibit a CAGR of 7.7% during the forecast period (2021-2028).

Figure 1. Global Biliary Atresia Treatment Market Share (%) in Terms of Value, by Disease Type, 2021

The increasing prevalence of biliary atresia and its surgery is expected to drive the market growth during the forecast period.

The increasing incidence of biliary atresia and its surgery is expected to drive the market growth during the forecast period. For instance, according to an article published by Research Gate in March 2016, babies born with biliary atresia during 1997 to 2010 were identified from the Taiwan National Health Insurance Research Database. Moreover, among 513 total biliary atresia cases, about 457 (89%) cases underwent the surgery (Kasai procedure).

Biliary Atresia Treatment Market Report Coverage

Report Coverage	Details
Base Year:	2020	Market Size in 2021:	US$ 910.7 Mn
Historical Data for:	2017 to 2020	Forecast Period:	2021 to 2028
Forecast Period 2021 to 2028 CAGR:	7.7%	2028 Value Projection:	US$ 1,527.9 Mn
Geographies covered:	North America: U.S. and Canada Latin America: Brazil, Argentina, Mexico, and Rest of Latin America Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific Middle East: GCC Countries, Israel, and Rest of Middle East Africa: South Africa, North Africa, and Central Africa
Segments covered:	By Disease Type: Type I, Type II, Type III By Treatment Type: Medications (Bile Acids, Antibiotics, Corticosteroids), Surgery
Companies covered:	AstraZeneca plc, Eisai Co., Ltd., Mirum Pharmaceuticals, Inc., Pfizer Inc., Albireo Pharma, Inc., Novartis AG, Alkem Labs, and Glenmark Pharmaceuticals
Growth Drivers:	Increasing prevalence of biliary atresia High demand for producing safe and effective therapy
Restraints & Challenges:	Safety concerns related to the drug High cost involved in the treatment Limited treatment options Lack of skilled professional in some developing countries like India, Kenya and others

Figure 2.Global Biliary Atresia Treatment Market Share (%), by Treatment Type, 2021

Increasing advancements in laboratory screening and diagnosis of biliary atresia is expected to drive the market growth during the forecast period.

The increasing advancements in laboratory screening and diagnosis of biliary atresia by researchers and key players are expected to drive the biliary atresia treatment market growth during the forecast period. For instance, according to an article published in the journal ‘Digestive Medical Research’ in September 2021, recent advancements in non-invasive molecular markers, such as gamma-glutamyl transpeptidase (GGT), matrix metalloproteinase-7 (MMP7), interleukin-33 (IL-33), and stool proteomics showed promising results as effective diagnostic markers in biliary atresia.

Global Biliary Atresia Treatment Market– Impact of Coronavirus (COVID-19) Pandemic

Due to the COVID-19 pandemic, pediatric liver research has faced a lot of challenges. The most impacted have been clinical research studies focusing on rare diseases like biliary atresia (BA), which is the most common indication for liver transplantation.

Biliary atresia studies done under the ‘The Childhood Liver Disease Research Network’ (ChiLDReN), an NIH-funded consortium and biorepository, has been largely interrupted during this COVID-19 pandemic, as there has been no new sample collection. Due to the failure to capture new cases of BA, the timeline of research progress will certainly be prolonged. Moreover, the diagnosis of BA has been delayed, as parents are scared of bringing their infants to their pediatrician’s hospital during this period for BA diagnosis.

As several pediatric liver diseases fall under the category of rare diseases, the unstable economic times and greatest impact of this pandemic on funding of pediatric liver research may be seen.

Global Biliary Atresia Treatment Market: Restraint

The major factors that hinder the growth of the global biliary atresia treatment market include safety concerns related to the drug, higher cost involved in the treatment, limited treatment options, and lack of skilled professional in some developing countries like India, Kenya and others.

Key Players

Major players operating in the global biliary atresia treatment market include AstraZeneca plc, Eisai Co., Ltd., Mirum Pharmaceuticals, Inc., Pfizer Inc., Albireo Pharma, Inc., Novartis AG, Alkem Labs, and Glenmark Pharmaceuticals

Table of Content

*Browse 28 market data tables and 24 figures on "Biliary Atresia Treatment Market” - Global forecast to 2028

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- Frequently Asked Questions -

What is the current market size and compound annual growth rate (CAGR) of the market during the forecast period (2021-2028)?

The global biliary atresia treatment market size is estimated to be valued at US$ 910.7 million in 2021 and is expected to exhibit a CAGR of 7.7% between 2021 and 2028.

What are the major factors driving the market growth?

Factors such as increasing prevalence of biliary atresia and high demand for producing safe and effective therapy is expected to drive the growth of the market during the forecast period.

Which is the leading type segment in the market?

Type III segment is the leading type segment in the market.

What are the key factors hampering growth of the market?

The major factors hampering growth of the market include safety concerns related to the drug, high cost involved in the treatment, limited treatment options, and lack of skilled professional in some developing countries like India, Kenya and others.

Which are the major players operating in the market?

Major players operating in the market include AstraZeneca plc, Eisai Co., Ltd., Mirum Pharmaceuticals, Inc., Pfizer Inc., Albireo Pharma, Inc., Novartis AG, Alkem Labs, and Glenmark Pharmaceuticals