Methadone hydrochloride market

Methadone Hydrochloride Market, by Formulation (Tablet, Solution, and Others), by Application (Opiate Withdrawal, Chronic Pain, and Others), by Route of Administration (Oral and Intravenous), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Outlook, and Opportunity Analysis, 2020 - 2027

  • Dec 2020
  • CMI4343
  • 180 Pages
  • Excel & Pdf
  • Pharmaceutical

Methadone hydrochloride is the hydrochloride salt of methadone, a synthetic opioid with analgesic activity. Methadone hydrochloride is similar to morphine and other morphine-like agents, and exhibit therapeutics actions against  analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. Methadone hydrochloride has prolonged half-life compared to other morphine-like agents such as heroin, the onset of opiate withdrawal symptoms is slower, the duration of opiate withdrawal is prolonged, and opiate withdrawal symptoms are less severe.

The global methadone hydrochloride market is estimated to be valued at US$ 105.3 million in 2020 and is expected to exhibit a CAGR of 4.0% during the forecast period (2020-2027).

Figure 1. Global Methadone Hydrochloride Market Value (US$ Mn), 2016-2027

The global methadone hydrochloride market is primarily driven by increasing prevalence of pain associated with therapeutic and post-surgical treatment, which in turn increases demand for methadone hydrochloride. For instance, according to the report published by the U.S. Department of Health & Human Services in September 2018, in 2016, an estimated 20.4% of the U.S. adults had chronic pain and 8.0% of the U.S. adults had high-impact chronic pain. Both chronic pain and high impact chronic pain were more prevalent among adults living under poverty.

Furthermore, development and launches of novel methadone hydrochloride products by key companies is expected to drive the market growth over the forecast period. For instance, in November 2018, Elite Pharmaceuticals, Inc., a specialty pharmaceutical company developing abuse-deterrent opioids and niche generic products, announced the commercial launch of generic methadone hydrochloride 5 mg and 10 mg tablets by Glenmark Pharmaceuticals, Inc., U.S., (Glenmark), Elite’s marketing alliance partner. Through this alliance, Glenmark will sell and distribute certain generic products of Elite, including methadone, for which Elite will receive manufacturing and license fees.

Methadone Hydrochloride Market Report Coverage

Report Coverage Details
Base Year: 2019 Market Size in 2020: US$ 105.3 Mn
Historical Data for: 2016 to 2019 Forecast Period: 2020 to 2027
Forecast Period 2020 to 2027 CAGR: 4.0% 2027 Value Projection: US$ 138.8 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC, Israel, and Rest of the Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Formulation: Tablet, Solution, Others.
  • By Application: Opiate Withdrawal, Chronic Pain, Others.
  • By Route of Administration: Oral, Intravenous.
  • By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies.
Companies covered:

Eli Lilly and Company, Sanofi S.A, Hikma Pharmaceuticals PLC, Mallinckrodt Pharmaceuticals, Siegfried Holding AG, Johnson Matthey, Tianjin Central Pharmaceutical Co., Ltd, Temad Co, Embio LTD, Harman Finochem Ltd, and Rusan Pharma Ltd

Growth Drivers:
  • Increasing prevalence of pain associated with therapeutic and post-surgical treatment
  • Increasing drug abuse globally
Restraints & Challenges:
  • Side effects such as constipation, nausea, sleepiness, vomiting, tiredness, headache, dizziness, and stomach pain and also, patients might get addicted to methadone hydrochloride are associated with use of methadone hydrochloride

Global Methadone Hydrochloride Market – Impact of Coronavirus (COVID-19)

Following the outbreak of COVID-19 in December 2019, the disease has spread to over 100 countries across the globe and the World Health Organization declared it a public health emergency. According to the World Health Organization’s report, manifestation of coronavirus (COVID-19) has resulted in more than 69.9 million infected individuals worldwide as of December 11, 2020.

Moreover, COVID-19 has impacted each and every market around the world, and is expected to affect the global methadone hydrochloride market. Therefore, governments of various countries are taking various initiatives to combat COVID-19. For instance, in May 2020, the Centers for Disease Control and Prevention started working with government agencies and research institutes to increase testing capacity, improve case detection, and contact tracing across all states in the U.S. and re-open the country.

Furthermore, In response to a reduction in the accessibility of COVID-19 treatment service provision during the lockdown, some countries have increased low-threshold services and reduced barriers for obtaining opiate-substitution medication; for instance, allowing pharmacies to dispense methadone such as in the U.K.  In order to increase accessibility to opioid-substitution therapy, the U.K. is planning to dispense methadone without new prescriptions to those who already use it, although the measure has triggered concerns by the Advisory Council on the Misuse of Drugs that it may lead to an increase in drug misuse and diversion.

Figure 2. Global Methadone Hydrochloride Market Share (%), By Region, 2020

North America is expected to hold dominant position in the global methadone hydrochloride market, owing to higher prevalence of chronic pain related to cancer and post-surgical pain. According to the report published by the Centers for Disease Control and Prevention (CDC) in 2018, over 1 in 5 adults in the U.S. experienced chronic pain in 2018

Key Players

Major players operating in the global methadone hydrochloride market include Eli Lilly and Company, Sanofi S.A, Hikma Pharmaceuticals PLC, Mallinckrodt Pharmaceuticals, Siegfried Holding AG, Johnson Matthey, Tianjin Central Pharmaceutical Co., Ltd, Temad Co, Embio LTD, Harman Finochem Ltd, and Rusan Pharma Ltd.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snapshot, By Formulation
      • Market Snapshot, By Application 
      • Market Snapshot, By Route of Administration
      • Market Snapshot, By Distribution Channel
      • Market Snapshot, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Drivers and Restraints
    • Opportunities
    • Impact Analysis
    • Recent Product launches and Approvals
    • Pipeline Analysis
    • Brand Analysis
    • Regulatory Scenario
    • PEST Analysis
    • Epidemiology
    • Reimbursement Scenario
    • Acquisition
    • Market Trend
  4. Global Methadone Hydrochloride Market, Impact of COVID-19 Pandemic
    • Economic Impact
    • Research and Development
    • Government Analysis
  5. Global Methadone Hydrochloride Market, By Formulation, 2016-2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
        • Tablet
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Solution
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Others
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
  6. Global Methadone Hydrochloride Market, By Application, 2016–2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
        • Opiate Withdrawal
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Chronic Pain
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Others
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
  7. Global Methadone Hydrochloride Market, By Route of Administration, 2016–2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
        • Oral
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Intravenous
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
  8. Global Methadone Hydrochloride Market, By Distribution Channel, 2016–2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
        • Hospital Pharmacies
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Retail Pharmacies
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
        • Online Pharmacies
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2016–2027, (US$ Mn)
  9. Global Methadone Hydrochloride Market, By Region, 2016–2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, By Country, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, For Countries, 2017–2027
    • North America
      • Introduction
      • Market Size and Forecast, By Formulation, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Application 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016–2027 (US$ Mn)
        • U.S.
        • Canada
    • Latin America
      • Introduction
      • Market Size and Forecast, By Formulation, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Application 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016–2027 (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Introduction
      • Market Size and Forecast, By Formulation, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Application 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016–2027 (US$ Mn)
        • Germany
        • U.K.
        • France       
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Introduction
      • Market Size and Forecast, By Formulation, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Application 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016–2027 (US$ Mn)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • Introduction
      • Market Size and Forecast, By Formulation, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Application 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2016–2027 (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Introduction
      • Market Size and Forecast, By Formulation, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Application 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Route of Administration, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2016–2027 (US$ Mn)
      • Market Size and Forecast, By Country/Region, 2016–2027 (US$ Mn)
        • South Africa
        • Central Africa
        • North Africa
  10. Competitive Landscape
    • Company Profiles
      • Eli Lilly and Company
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Sanofi S.A
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Hikma Pharmaceuticals PLC
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Mallinckrodt Pharmaceuticals
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Siegfried Holding AG
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Johnson Matthey
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Tianjin Central Pharmaceutical Co., Ltd
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Temad Co
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Embio LTD
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Harman Finochem Ltd
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Rusan Pharma Ltd
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies

*Browse 44 market data tables and 34 figures on " Methadone Hydrochloride Market – Global forecast to 2027”.

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- Frequently Asked Questions -

What is the current market size and compound annual growth rate (CAGR) of the market during the forecast period (2020-2027)?

The global methadone hydrochloride market size is estimated to be valued at US$ 105.28 million in 2020 and is expected to exhibit a CAGR of 4.0% between 2020 and 2027.

What are the major drivers for growth of the global methadone hydrochloride market?

Increasing prevalence of pain associated with therapeutic and post-surgical treatment and increasing drug abuse globally are the factors that are expected to drive growth of the global methadone hydrochloride market.

Which is the leading formulation type segment in the global methadone hydrochloride market?

Tablet segment is estimated to hold major market share in the global methadone hydrochloride market during the forecast period, owing to key players focusing on product launches and product approvals from the regulatory bodies.

Which is the leading application segment in the global methadone hydrochloride market?

Chronic pain segment is estimated to hold major market share in the global methadone hydrochloride market during the forecast period, owing to rising prevalence of pain associated with therapeutic and post-surgical treatment in cancer and other diseases treatment therapy.

Which is the leading route of administration segment in the global methadone hydrochloride market?

Oral segment is estimated to hold major market share in the global methadone hydrochloride market during the forecast period, owing to advantages offered by oral route of administration include patient safety, good patient compliance, ease of ingestion, pain avoidance, and versatility to accommodate various types of drugs.

Which is the leading distribution channel segment in the global methadone hydrochloride market?

Hospital pharmacies segment is estimated to hold major market share in the global methadone hydrochloride market during the forecast period, owing to the increasing number of patient’s emergency visits to hospitals due to opioid overdose, and agreements of hospitals with specialty pharmacies services providers.
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