Cell-free protein expression, also known as in vitro translation, in vitro protein expression, cell-free translation, or cell-free protein synthesis, is the production of recombinant proteins in cell lysates rather than within cultured cells. Cell-free protein expression uses the biomolecular machinery with all the components extracted from the desired cell type. Cell-free protein expression system is a rapid, simple, and sensitive tool that is devoid of membrane-bound barriers, yet contains all the mandatory substrates, machineries and biomolecules which are required for the synthesis of the desired proteins. Cell-free protein expression system is a powerful tool in biological research as it can be used for numerous applications such as assembly of viruses, expansion of genetic code, in metabolic engineering for production of toxic and complex proteins, etc. In order to produce a protein of interest, cell-free protein expression systems use crude extracts such as Escherichia coli, rabbit reticulocytes, wheat germ (WGE), insect cells, or commercially available systems of purified recombinant elements (PURE).
Market Dynamics
Increasing prevalence of chronic diseases, such as cancer, growing demand for targeted and personalized medicine, rising research and development activities by market players, and increasing adoption of inorganic growth strategies such as acquisitions and collaborations by key players operating in the market are the major factors that are expected to drive growth of the global cell-free protein expression market over the forecast period.
For instance, according to data published in the GLOBOCAN 2020 report by the Global Cancer Observatory in December 2020, it is estimated that around 19.3 million new cancer cases (18.1 million excluding nonmelanoma skin cancer) and around 10.0 million cancer deaths (9.9 million excluding nonmelanoma skin cancer) were reported in 2020, globally.
Key features of the study:
- This report provides an in-depth analysis of the global cell-free protein expression market, and provides market size (US$ Mn) and compound annual growth rate (CAGR%) for the forecast period (2022–2030), considering 2021 as the base year
- It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
- This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
- It profiles key players in the global cell-free protein expression market based on the following parameters – company overview, financial performance, Material portfolio, market presence, distribution strategies, key developments, strategies, and future plans
- Key companies covered as a part of this study include Thermo Fisher Scientific, Inc., Takara Bio, Inc., Promega Corporation, New England Biolabs, Jena Bioscience GmbH, GeneCopoeia, Inc., Cube Biotech GmbH, CellFree Sciences Co., Ltd., Moderna Therapeutics, Biotechrabbit GmbH, Bioneer Corporation, Merck KGaA, Bio-Rad Laboratories, Inc., Daicel Arbor Biosciences Daicel Arbor Biosciences, Profacgen, Creative Biolabs, biotechrabbit, Roche Molecular Systems, Inc., Cusabio Technology LLC, and LenioBio
- Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future Material launches, type up-gradation, market expansion, and marketing tactics
- The global cell-free protein expression market report caters to various stakeholders in this industry including investors, suppliers, material manufacturers, distributors, new entrants, and financial analysts
- Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global cell-free protein expression market
Detailed Segmentation:
- Global Cell-Free Protein Expression Market, By Product Type:
- E. coli Cell-free Protein Expression System
- Rabbit Reticulocytes Cell-free Protein Expression System
- Wheat Germ Cell-free Protein Expression System
- Insect Cells Cell-free Protein Expression System
- Mammalian Cell-free Protein Expression System
- Labelling Tags
- Others (Vectors, yeast cell extracts, among others)
- Global Cell-Free Protein Expression Market, By Expression Mode:
- Continuous flow Expression
- Batch Expression
- Global Cell-Free Protein Expression Market, By Application:
- Enzyme Engineering
- Protein Labeling
- Protein-Protein interaction
- Protein Purification
- Others (High Throughput Production, among others)
- Global Cell-Free Protein Expression Market, By End User:
- Biotechnological Companies
- Pharmaceutical Companies
- Contract Research Organizations
- Academic/ Research Institutes
- Global Cell-Free Protein Expression Market, By Region:
- North America
- Latin America
- By Country
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- Europe
- By Country
- Germany
- U.K.
- France
- Italy
- Spain
- Russia
- Rest of Europe
- Asia Pacific
- By Country
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of Asia Pacific
- Middle East
- By Country
- GCC
- Israel
- Rest of Middle East
- Africa
- By Country/Region
- South Africa
- Central Africa
- North Africa
- Company Profiles
- Thermo Fisher Scientific, Inc.*
- Company Overview
- Material Portfolio
- Financial Performance
- Key Highlights
- Market Strategies
- Takara Bio, Inc.
- Promega Corporation
- New England Biolabs
- Jena Bioscience GmbH
- GeneCopoeia, Inc.
- Cube Biotech GmbH
- CellFree Sciences Co., Ltd.
- Moderna Therapeutics
- Biotechrabbit GmbH
- Bioneer Corporation
- Merck KGaA
- Bio-Rad Laboratories, Inc.
- Daicel Arbor Biosciences
- Profacgen
- Creative Biolabs
- Biotechrabbit
- Roche Molecular Systems, Inc.
- Cusabio Technology LLC
- LenioBio
“*” marked represents similar segmentation in other categories in the respective section.
