Global Tooth Regeneration Market, By Application (Enamel, Dentin, Pulp), Population Demographics (Geriatrics, Middle Aged, Adult), and Geography - Insights, Opportunity Analysis, and Industry Forecast till 2024

Tooth Regeneration

Global dental industry has undergone a drastic transformation over the last decade. Teeth are among the most important part of human beings, which helps in performing various activities ranging from feeding to articulation to that of esthetics, loss of which could led to physical and psychological issues. As such, many advancements have been made in the past to cater to growing dental issues among patients, including denatures and dental implants. Though major advancements has been made in the field of dentistry, emotional connect with natural teeth and high attributes of natural teeth has led to attention on development of biologically engineered teeth (tooth regeneration). Various new companies have emerged at the global level to address and capitalize on highly lucrative opportunities in the market. Industry leaders and universities across regions are actively working towards developing novel products and solutions to develop new teeth. Once commercialized, tooth regeneration market is expected to capture much of the dental implants market.

Research are carried out by various universities and companies to understand the feasibility of stem cell based regenerative medicines – tooth regeneration. While stem cell is the prominent technology in research for tooth regeneration, some institutions are also leveraging laser, drug and gel as mediums to regenerate teeth. For instance, Wyss Institute at Harvard University is engaged in research related to tooth regeneration using lasers. Tooth generated using stem cells are currently under research across the globe. Dental pulp stem cells, stem cells from human exfoliated deciduous teeth (SHEDs), periodontal ligament stem cells (PDLSCs), stem cells from apical papilla (SCAPs), dental follicle progenitor cells (DFPCs) are key stem cells on which research are carried out.

Tooth regeneration market industry players are expected to witness increase exponential increase in their revenue. Early entrants are expected to gain significantly from first mover advantage. The market is expected to be primarily driven by high tooth loss prevalence coupled with focus of major players on product innovation and need for aesthetic look among target population. Dental cavities and issues are treated with conventional invasive methods such as dental implants and root canal. Development of non-invasive methods such as tooth regeneration would be a major breakthrough innovation and would replace dental implants. A 2009 nationwide survey by the Nova Southeastern University in the U.S. revealed that around 96% of dentists expect stem cell regeneration to dominate the future of dentistry industry.

Tooth regeneration market revenue is expected to be further driven by various macroeconomic factors. Various regulatory issues coupled with increasing spending on dental healthcare is expected to further support growth of tooth regeneration market growth. Favorable demographic trends along with expansion of commercial insurance and Medicaid insurance represents favorable market environment for growth of dental products, including those undergoing research. Moreover, global dental care expenditure is expected to rise at 5% annually between 2016 and 2024.

The global tooth regeneration addressable market is expected to be pegged at an astounding 4,633.3 million dental implant procedures by 2024 and is expected to expand at a CAGR of 7.1% during the period 2016 – 2024. However, commercialization of the product is expected to take place post-2024.

Figure 1. Global Tooth Regeneration Addressable Market

Tooth Regeneration

Source: Coherent Market Insights Analysis (2016)

Geriatric population demographics has emerged as the highest revenue contributor among population demography segment

Geriatric segment is expected to dominate the dental implants market throughout the forecast period. The segment accounted for 66.8% of global industry revenue in 2015. According to NIH, geriatric population have average 18.9 remaining teeth. Around 23% of geriatric population have no teeth, creating favorable market scenario for industry players. Over 18 million dental procedures are expected to be carried out among geriatric population between 2017 and 2024. Commercialization of tooth regeneration is expected to create lucrative market opportunity for industry players. North America and Europe are expected to collectively account for major share of global procedures by 2024.

Asia Pacific is expected to dominate the tooth regeneration market revenue post 2020

Tooth regeneration addressable market is expected to be highest in Asia Pacific, with China and India positioned as the major growth engines. Emergence of tooth regeneration is expected to capture this market. Also, the number of dental procedures is expected to grow at the highest CAGR of 9.7% in Asia Pacific between 2016 and 2024.

North America and Europe are expected to lose position to Asia Pacific by 2020. It is primarily attributed to increasing healthcare spending coupled with significant geriatrics population presence in Asia Pacific.

Tooth regeneration market players need to invest in R&D to harness stem cell technology to develop and commercialize tooth regeneration technology

Tooth regeneration market players are focused towards research and development to commercialize the target industry. Companies such as Straumann and DENTSPLY are working closely with some of the leading universities to understand the project feasibility. In 2015, researchers at University of Southern California (U.S) created gel to regrow enamel. Moreover, nanoparticles is also gaining momentum to boost dental tissue engineering. Various institutes such as Nova Southeastern University, Tufts School of Dental Medicine, University of Southern California, Wyss Institute at Harvard University, University of Nottingham, Institute National de la Sante et de la Recherche Medicale (France), etc are engaged in tooth regeneration technology. Various products are in the pipeline, commercialization of which is expected to happen post-2024. Most of these companies are focused towards enamel regeneration. Unilever UK developed ‘Regenerate Enamel Science’. The company holds 5 international patents for its NR-5 technology. The brand claims to regenerate 82% of the eroded enamel within 3 days. Many products are expected to emerge in near future creating exponential market opportunity for industry players.

Tooth regeneration market has been abuzz for a while with various new developments reported, commercialization of which is expected to transform whole dental industry. Though the development in tooth regeneration has been on upward growth trajectory since 1980s, it gained momentum post-2013. Many research institutes are focusing on conducting studies to understand the feasibility of tooth regeneration.  While Asia Pacific is expected to dominate the addressable market, North America and Europe are expected to witness early launch of tooth regeneration products in near future. Asia Pacific market is expected to expand at the fastest CAGR, followed by Latin America and Middle East, respectively over the forecast period (2016-2024).

Market Dynamics

With changing dental industry landscape, companies are emphasizing on product innovation in order to sustain and expand their business reach worldwide. Tooth regeneration is one such disruptive technology wherein early entrants are expected to capture major share of the dental market. Moreover, commercialization of tooth regeneration will lead to slowdown in the dental implant and equipment landscape. As such, tooth regeneration industry will dominate the whole dental market. Though the tooth regeneration holds immense potential to generate high ROI and at same time benefit society, high R&D cost and stringent regulations are key challenges being faced by the industry players. Tooth regeneration is expected to be commercialized on large scale post-2024.

Market Taxonomy

This report segments the tooth regeneration market on the basis of application and population demographics. On the basis of application, the market is segmented into enamel, dentin and pulp. On the basis of population demographics, the tooth regeneration market is segmented as geriatric, middle aged, adults and others.

Key features of the study:

  • This report provides in-depth analysis of the tooth regeneration market and provides the number of dental procedures and Cumulative Annual Growth Rate (CAGR) (%) for the forecast period (2016 – 2024), considering 2015 as the base year.
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides valuable insights about market drivers, restraints, opportunities, new product launches or approval, regional outlook, and competitive strategy adopted by the leading players
  • The report takes into account critical limiting factors such as accuracy issues and need for calibrating the device several times a day while analyzing the market value and growth (%) during the forecast period
  • It includes insights on population dynamics, number of dental clinic centers, and demand for dental implants across the globe.
  • It profiles leading players in the global dental implants market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments, and strategies and future plans
  • Key companies covered as a part of this study include Institut Straumann Ag, DENTSPLY Implants, Unilever and Datum Dental.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions with respect to their future product launch, technology upgrade, market expansion, and marketing tactics
  • The global dental implants market report caters to various stakeholders in this industry, including investors, raw material manufacturer, contract manufacturer, device manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would greatly benefit in decision making through the various strategy matrices used in analyzing the dental implants market.

Detailed Segmentation:

  • Global Tooth Regeneration Market, By Application:
    • Enamel
    • Dentin
    • Pulp
  • Global Tooth Regeneration Market, By Population Demographics:
    • Geriatrics
    • Middle Aged
    • Adult
    • Others
  • Global Tooth Regeneration Market, By Geography:
    • North America
      • Global Tooth Regeneration Market, By Application:
        • Enamel
        • Dentin
        • Pulp
      • Global Tooth Regeneration Market, By Population Demographics:
        • Geriatrics
        • Middle Aged
        • Adult
        • Others
      • Europe
        • Global Tooth Regeneration Market, By Application:
          • Enamel
          • Dentin
          • Pulp
        • Global Tooth Regeneration Market, By Population Demographics:
          • Geriatrics
          • Middle Aged
          • Adult
          • Others
        • Asia-Pacific
          • Global Tooth Regeneration Market, By Application:
            • Enamel
            • Dentin
            • Pulp
          • Global Tooth Regeneration Market, By Population Demographics:
            • Geriatrics
            • Middle Aged
            • Adult
            • Others
          • Latin America
            • Global Tooth Regeneration Market, By Application:
              • Enamel
              • Dentin
              • Pulp
            • Global Tooth Regeneration Market, By Population Demographics:
              • Geriatrics
              • Middle Aged
              • Adult
              • Others
            • Middle East
              • Global Tooth Regeneration Market, By Application:
                • Enamel
                • Dentin
                • Pulp
              • Global Tooth Regeneration Market, By Population Demographics:
                • Geriatrics
                • Middle Aged
                • Adult
                • Others
              • Africa
                • Global Tooth Regeneration Market, By Application:
                  • Enamel
                  • Dentin
                  • Pulp
                • Global Tooth Regeneration Market, By Population Demographics:
                  • Geriatrics
                  • Middle Aged
                  • Adult
                  • Others
                • Company Profiles
                  • Institut Straumann Ag *
                    • Company Overview
                    • Product Portfolio
                    • Financial Performance
                    • Recent Developments
                  • DENTSPLY Implants
                  • Unilever
                  • Datum Dental

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet By Population Demographics
      • Market Snippet By Region
    • Tooth Regeneration Technologies Under Research
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Why Tooth Regeneration?
    • Shift in dental Market Trends
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Research Update
    • Epidemiology/Prevalence/Incidence
  4. Global Tooth Regeneration Market, By Application
    • Introduction
    • Enamel
      • Research Activities
      • Addressable Market
      • Product Overview
    • Dentin
      • Research Activities
      • Addressable Market
    • Pulp
      • Research Activities
      • Addressable Market
  5. Global Tooth Regeneration Market, By Population Demographics, 2014 - 2024 (Number of Dental Implant Procedures)
    • Introduction
      • Market Share Analysis, 2015 and 2024 (%)
      • Y-O-Y Growth Analysis, 2014 - 2024
      • Segment Trends
    • Geriatric
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2014 - 2024, (Number of Dental Implant Procedures)
    • Middle-aged
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2014 - 2024, (Number of Dental Implant Procedures)
    • Adults
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2014 - 2024, (Number of Dental Implant Procedures)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2014 - 2024, (Number of Dental Implant Procedures)
  6. Global Tooth Regeneration Market, By Regions, 2014 - 2024 (Number of Dental Implant Procedures)
    • Introduction
      • Market Share Analysis, By Region, 2015 and 2024 (%)
      • Y-O-Y Growth Analysis, For Regions, 2014 - 2024
    • North America
      • Estimate and Projection: Number of Dental Implant Procedures
      • Market Size and Forecast, and Y-o-Y Growth, By Population Demographics, 2014 - 2024
    • Europe
      • Estimate and Projection: Number of Dental Implant Procedures
      • Market Size and Forecast, and Y-o-Y Growth, By Population Demographics, 2014 - 2024
    • Asia Pacific
      • Estimate and Projection: Number of Dental Implant Procedures
      • Market Size and Forecast, and Y-o-Y Growth, By Population Demographics, 2014 - 2024
    • Latin America
      • Estimate and Projection: Number of Dental Implant Procedures
      • Market Size and Forecast, and Y-o-Y Growth, By Population Demographics, 2014 - 2024
    • Middle East
      • Estimate and Projection: Number of Dental Implant Procedures
      • Market Size and Forecast, and Y-o-Y Growth, By Population Demographics, 2014 - 2024
    • Africa
      • Estimate and Projection: Number of Dental Implant Procedures
      • Market Size and Forecast, and Y-o-Y Growth, By Population Demographics, 2014 - 2024
  7. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • Institut Straumann AG*
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Developments/Updates
      • DENTSPLY Implants
      • Datum Dental
      • Unilever
    • Analyst Views
  8. Section
    • Analyst Views
    • References
    • Research Methodology
    • About Us and Sales Contact

“*” marked represents similar segmentation in other categories in the respective section.

*Browse 8 market data tables and 17 figures on "Tooth Regeneration Market - Global addressable market forecast to 2024”.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
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Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
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