Bioresorbable polymers, also known as degradable polymers, are commonly used in various biomedical applications such as suturing thread, arterial stents, intravenous drug-delivery devices, vascular grafts, temporary bone fixation devices, and degradable sutures. These polymers are used as a replacement for metallic orthopedic devices due to their precise control of material composition and microstructure. Various bioresorbable polymers used in medical applications include polylactic acid (PLA), polyglycolic acid (PGA), and poly (lactic-co-glycolide) (PLGA) copolymers. Polylactic acid (PLA), or polylactide, is the most commonly used bioresorbable polymer. It is majorly used in synthetic grafts, orthopedic medicine, sutures, and drug delivery systems. Polyglycolic acid (PGA), or polyglycolide, another type of bioresorbable polymer is generally used in bioresorbable sutures, orthopedics, and craniomaxillofacial surgery.
Bioresorbable Polymers Market Dynamics
Bioresorbable polymers find applications in the medical field, as they are completely biodegradable inside the human body, which in turn avoid the need for second surgery and reduces post-surgery risks. Drug delivery is one of the most commonly used applications of bioresorbable polymers. Poly (D, L-lactic-co-glycolic acid) (PLGA) is the most frequently used bioresorbable polymer for the controlled release of drugs. Various pharmaceutical ingredients such as anti-cancer drugs and antibiotics can be delivered with controlled and constant release by using timely biodegradation of the drug carrier. PLGA is majorly studied for localized drug delivery for treating cancer, glaucoma, and periodontal diseases, and to coat biodegradable and metallic stents. For instance, drug-eluting stents (DES) have shown significant advantages in comparison to their bare metal stent predecessors in reducing the risk of a recurring blockage (restenosis). Bioresorbable polymers market is expected to gain significant traction during forecast period due to high usage in surgery and pharmaceutics such as artificial skin, biodegradable sutures, and implantable carriers for drug delivery. Over the recent past, PLAs are significantly researched upon due to their biodegradability and biocompatibility, leading to applications in medical science. Moreover, ongoing research on 3D printing, is expected to boost growth of the bioresorbable polymers market.
Increasing government efforts to upgrade health sector is driving growth of the bioresorbable polymers market. For instance, government awareness regarding more sustainable products have gained significant traction in the past decade and are guiding future research on the next generation processes and materials. Various funding agencies such as the Bill and Melinda Gates Foundation fund support both, industrial and academic research to overcome product development challenges in manufacturing, frequency of administration, supply chain, and pricing limitations. Recent research on new and improved products is focused on more sophisticated biomedical applications to provide higher efficacy and minimize pain. For instance, in April 2018, Evonik, a global leader for advanced biomaterials and application technology solutions for bioresorbable implants, launched its first product from a new line of RESOMER composite polymers. With the launch of RESOMER, the company will support medical device customers to enhance the performance of orthopedic applications used to grow or heal bones by integrating the osteoconductive properties of calcium-phosphate-based additives into RESOMER.
However, certain limitation of these polymers such as tendency to degrade during fabrication and storage and moisture sensitivity are expected to hinder growth of the bioresorbable polymers market. These products also lack the tensile strength of metals for load bearing applications, posing as a major restraint for market growth. Moreover, increasing number of regulatory policies affecting the approval of newer products, are also hindering market growth. Several ensembles of instructions are available for manufacturers to comply with the international and local medical device regulations, such as American Society for Testing Materials or MEDDEV.
Bioresorbable Polymers Market Regional Insights
Regional segmentation of the bioresorbable polymers market by Coherent Market Insights, includes North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. The market in North America is expected to hold a dominant position in the bioresorbable polymers market due to rampant advancements in technology related to the bioresorbable polymers and presence of major industry players such as Poly-Med Inc. in the region. Furthermore, market in Asia Pacific is expected to gain significant traction, owing to rising demand for bioresorbable polymers in drug delivery and orthopedics applications and the growing healthcare spending in the region. According to DBS report 2016, healthcare spending in Asia Pacific is estimated to grow CAGR of 12.8% due to rising geriatric population, increase in chronic illnesses, and urbanization. Rising affluence and a surge in lifestyle diseases are additional key structural drivers for the market growth. According to Securities Investors Association (SIAS), in 2018, India and China have the largest number of diabetes sufferers in the world, accounting for around 69 million and 114 million, respectively. Moreover, according to Organisation for Economic Co-operation and Development (OECD), cancer is the second-leading cause of death after cardiovascular disease in the region.
Bioresorbable Polymers Market Competitive Landscape
Key players operating in the bioresorbable polymers market include Corbion N.V., DSM, Degradable Solutions, Evonik Industries AG, Foster Corporation, Galatea Surgical, KLS Martin, LACTEL Absorbable Polymers, MAST Biosurgery, Poly-Med Inc., and Sigma-Aldrich.
Bioresorbable Polymers Market Taxonomy
On the basis of polymer type, the bioresorbable polymers market is segmented into:
On the basis of application, the bioresorbable polymers market is segmented into: