Increasing patient awareness and rising demand for high quality care have made it imperative for healthcare providers to develop targeted therapies through specific and sensitive diagnostic tests. Clinical diagnostic tests are used to diagnose a medical condition, provide information about the patient’s health, or monitor a course of disease and assess the patient’s response to treatments. Various techniques of clinical diagnostic testing include blood gas testing, clinical chemistry, immunoassay, coagulation testing, hematology, polymerase chain reaction (PCR), and staining method.
Typically, clinical diagnostic tests involve use of antibody-based techniques for recognizing proteins or disease markers. However, these immunoassays cannot identify all biomarkers in one test and are prone to false-positive and false-negative results. Therefore, there is growing demand for more accurate, efficient, and reliable technologies. This has led to development of alternative testing methods such as LC-MS and GC-MS. However, high initial capital investment and lack of skilled labor is deterring adoption of advance testing devices. Major instruments used in clinical diagnostics include immunoassay analyzer, HPLC system, chemical analyzer, mass spectrometer (MS), LC-MS, and GC-MS. The use of reagents has simplified the testing practice and workflow for personnel in diagnostic laboratories.
New Techniques in Use
Molecular diagnostics is driving growth of the personalized medicine market which involves co-development of drugs/devices and specialized diagnostic tests. The technique is also referred to as companion diagnostic and can be used for toxicity studies, dose selection, monitoring patient response, and patient stratification.
Rapid diagnostic tests are performed at the physician office laboratory (POL), hospitals, health centers and home care. Demand for these tests is increasing rapidly owing to faster and accurate results. Tests have been developed for HbA1c testing, drug abuse, pregnancy testing, micro albumin, creatinine, blood gases, RSV, etc.
Demand for In-vitro diagnostics (IVD) is increasing in emerging markets such as India, China, Brazil, and South Korea. In-vitro diagnostic techniques have transformed the diagnostics industry by eliminating the complex in-vivo testing methods. The IVD techniques include the advance PCR technique, assays and hematology testing, helps diagnose and monitor patient’s health condition using samples of blood, cells or tissues.
Immunoassay diagnostics is expected to be driven by technological advancements such as novel biomarkers, ultrasensitive detection system and assays.
The diagnostic landscape, especially in the emerging countries, is highly fragmented and marked by the strong presence of unorganized diagnostic labs. Global players are now building global networks by investing in foreign markets. Moreover, in terms of manufacturers, the market is fragmented in a similar manner with many small players dominating local markets. Owing to the increasing demand for home care, manufacturers and diagnostic laboratories need to work in collaboration to provide quality care at patient convenience.
Increasing healthcare costs is deterring patients from undergoing regular health tests that can be improved with a wider insurance coverage. Inadequate insurance coverage in emerging economies is restricting patients from undergoing expensive health tests, thus fueling the market growth. Moreover, centralization of testing laboratories is projected to drive demand for high volume instrumentation and automation equipment. Demand for IVD tests from Asia Pacific, Latin America and the Middle East markets is also increasing rapidly.
Chemiluminescence (CL) is the emission of electromagnetic radiation as a result of a chemical reaction that produces light. Chemiluminescence immunoassay (CLIA) is a technique that combines chemiluminescence with immunochemical reactions. To label the antibody, CLIA e... Read more
Preeclampsia is a major cause of illness and deaths among mothers and their babies globally. Preeclampsia is a kind of high blood pressure that occur in some women after the 20th week of pregnancy or after giving birth. This severe pregnancy disorder occurs in up to 5... Read more
Lung cancer is a type of cancer, which starts in the lungs. There are two main types of lung cancer and they are treated differently such as non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC).According to American Cancer Society around 80% to 85% of ... Read more
Polyclonal antibodies are a heterogeneous mix of antibodies derived from the immune response of multiple B-cells, in which each one recognizes a different epitope on the same antigen. Polyclonal antibodies are composed of a mixture of antibodies that represent the nat... Read more
Technological advancements in the disease diagnostic field has led to advanced product development. Key manufacturers are focused on developing new ophthalmoscopes for unmet need of ophthalmic diagnostic practices. The increasing product launches by key players is exp... Read more
Chromatography is widely used in various life science applications. It finds application in the food industry for spoilage detection, additive detection, and determining nutritional quality. In forensics, it is used for crime scene testing and forensic pathology. ... Read more
Tumor biomarkers tests use in diagnosis of cancer include, prostate specific antigen (PSA), circulating tumor cells (CTC), Alfa-fetoprotein test (AFP), CA-19 test for pancreatic cancer, HER-2 test, BRCA test, ALK test for lung cancer, carcioembryonic test (CEA), EGFR ... Read more
Cervical cancer occurs in the cells of the cervix. Pap smear, colposcopy, and ECC test are performed for the diagnosis of cervical cancer. Increasing awareness regarding cervical cancer and increasing prevalence of cervical cancer in emerging economies are expected to... Read more
Sexually Transmitted Diseases (STDs) are diseases that spread primarily through person-to-person sexual contact. Early identification or diagnosis of STDs and partner notification can help halt further transmission. Statist... Read more
In vitro toxicology testing is used to examine the toxic properties of compounds and mixtures on cultured bacteria or mammalian cells. Absorption, distribution, metabolism, and excretion (ADME), and toxicological profiling plays a major role in drug development. It fo... Read more
COVID-19 is a viral infection which affects the respiratory tract. The COVID-19 virus is highly contagious and can be transmitted through direct contact with the infected person or an indirect contact with surfaces in the immediate environment. The number of people ge... Read more
Biopsy is a procedure of removing of a small amount of tissue for examination under a microscope. Imaging tests may suggest the diagnosis of sarcoma, but biopsy is performed to confirm the diagnosis and to find out the type of sarcoma. Several types of biopsies are us... Read more
Methicillin Resistant Staphylococcus aureus (MRSA) is the most prevalent multi-drug resistant bacteria and a growing threat to health. The Centers for Disease Control and Prevention estimates that around 1 in 50 people in the U.S. carried MRSA in their noses as of Aug... Read more
Sleep Testing Services Market – Insights Sleep Study/Polysomnography is a type of test conducted to diagnose sleep disorders. Sleep study test records brain waves, oxygen level in blood, heart rate and brea... Read more
PARP Inhibitor Biomarkers Market – Market Insights PARP are poly(adenosine diphosphate [ADP] -ribose) polymerase. It is a group of 17 enzymes that combine several (poly) units of ADP-ribose in a chain... Read more
North America Outbound Medical Tourism Services Market – Insights Medical tourism is defined as traveling of patients to various destinations, seeking medical treatment. Medical tourism can be classified as... Read more
Rheumatoid Arthritis Diagnostic Tests Market – Insights Rheumatoid arthritis (RA) is an autoimmune disease in which the body’s own immune system attacks its joint tissues, which leads to inflammation ... Read more
Renal Biomarkers Market – Insights A biomarker can be defined as a biological characteristic of an organism that is measured as an indicator of normal biological process. Renal biomarkers are an important t... Read more