Contact Us
Phase-Xs | Biologics & Biosimilars | Coherent Market Insights

Demineralized bone matrix (DBM) is an osteoconductive and osteoinductive commercial biomaterial. It is an approved medical device used in bone defects, it has a long track record of clinical use in diverse forms. Demineralized bone matrices are prepared by acid extraction of allograft bone, resulting in loss of most of the mineralized component but retention of collagen and non-collagenous proteins including growth factors. Demineralized bone matrix is used to extend and bolster the bone graft. This is due to the ability of growth factors to control the differentiation of progenitor cells, which are responsible for bone and cartilage formation.

The Global Demineralized Bone Matrix Market is estimated to be valued at US$ 619.5 million in 2021 and is expected to exhibit a CAGR of 4.3 % during the forecast period (2021-2028).

Figure 1.Global Demineralized Bone Matrix Market Share (%) in Terms of Value, By Type, 2021

Demineralized Bone Matrix  | Coherent Market Insights

Rising incidence of orthopedic disorders is expected to drive the market growth during the forecast period.

Rising incidence of orthopedic disorders is expected to boost the global demineralized bone matrix market growth over the forecast period. For instance, according to the National Institute of Health and Family Welfare (NIHFW) (under the Ministry of Health and Family Welfare (MoHFW)), Government of India’s data, osteoarthritis is the second most common rheumatologic problem in India, and it is the most frequently diagnosed joint disease in India with a prevalence of 22% to 39% in 2018.

request-sample

Demineralized Bone Matrix Market Report Coverage

Report Coverage Details
Base Year: 2020 Market Size in 2021: US$ 619.5 Mn
Historical Data for: 2017 to 2020 Forecast Period: 2021 to 2028
Forecast Period 2021 to 2028 CAGR: 4.3% 2028 Value Projection: US$ 832.6 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Type: Gel, Putty, Putty with Chips, Others
  • By Applications: Dental, Spine Surgery, Trauma Surgery
  • By End User: Hospitals, Specialty Clinics, Others
Companies covered:

Medtronic Plc, Johnson & Johnson (DePuy Synthes), Exactech, Inc., HansBioMed, Xtant Medical, Stryker, Arthrex GmbH, RTI Surgical, Zimmer Biomet., and Straumann

Growth Drivers:
  • Rising incidence of orthopedic disorders 
  • Increasing number of spinal fusion and dental surgeries
Restraints & Challenges:
  • High cost of demineralized bone matrix

Figure 2.Global Demineralized Bone Matrix Market Share (%), By Application, 2021

Demineralized Bone Matrix  | Coherent Market Insights

Increasing number of spinal fusion and dental surgeries are expected to drive the market growth during the forecast period.

Increasing number of spinal fusion and dental surgeries are expected to boost the market growth during the forecast period. For instance, according to National Spinal Cord Injury Statistical Center in 2018, the U.S. had around 17,700 new cases of spinal cord injury, and the number of people living with the spinal cord injury were found out to be around 288,000.

Global Demineralized Bone Matrix Market– Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe and the World Health Organization has declared it a public health emergency. According to the World Health Organization’s report, the manifestation of coronavirus (COVID-19) has resulted in more than 191 million infected individuals worldwide as of July 21, 2021.

COVID-19 can affect the economy in three main ways; by directly affecting production and demand, by creating disruptions in distribution channels, and through its financial impact on firms and financial markets. Due to nationwide lockdowns, several countries such as China, India, Saudi Arabia, UAE, Egypt, and others are facing problems with regards to transportation of drugs from one place to another.

Furthermore, players operating in the global demineralized bone matrix market are facing major challenges on various fronts due to the COVID-19 pandemic. The major challenges include the supply of raw materials required for manufacturing drug formulations due to irregularities in transportation. Moreover, distributors are experiencing irregular demand of products from the retailers due to an increase in the number of patients suffering from COVID-19 and other life threatening disorders.

Global Demineralized Bone Matrix Market: Restraint

The major factors that hinder growth of the global demineralized bone matrix market include the high cost of demineralized bone matrix. For instance, the average cost of dental bone graft vary between US$ 400 and US$ 1,200 for end users in the U.S.

Key Players

Major players operating in the global demineralized bone matrix market are Medtronic Plc, Johnson & Johnson (DePuy Synthes), Exactech, Inc., HansBioMed, Xtant Medical, Stryker, Arthrex GmbH, RTI Surgical, Zimmer Biomet, and Straumann

Demineralized bone matrix (DBM) is prepared from cortical bone that is derived from long bones. It is an allograft bone in which the inorganic mineral is removed and leaving behind the collagen matrix. The removal of the bone mineral exposes more biologically active bone morphogenetic proteins. Demineralized bone matrix is indicated to extend and strengthen the bone graft. This is due to the ability of growth factors to control the differentiation of progenitor cells, which are responsible for bone and cartilage formation. Demineralized bone matrix (DBM) is more biologically active as compared to mineralized bone grafts and aids in bone generation.

Market Dynamics

Key players operating in the global demineralized bone matrix market are focusing on adoption of growth strategies such as product launch and agreement, which is expected to boost the market growth during the forecast period. For instance, in July 2019, SeaSpine Holdings Corporation, a global medical technology company focused on surgical solutions for the treatment of spinal disorders, announced the product release of its OsteoStrand and OsteoStrand Plus demineralized bone fibers with its new integrated, hydration syringe system.  Furthermore, in August 2018, BONESUPPORT, an emerging leader in orthobiologics for the management of bone voids, signed an agreement with MTF Biologics, the world’s largest tissue bank, to extend and strengthen its U.S. product offering. This agreement gave BONESUPPORT the U.S. rights to sell two forms of bone graft materials that are comprised of 100% demineralized bone matrix. BONESUPPORT launched the products supplied by MTF Biologics under BONESUPPORT brand name and distributed them through its own U.S. distribution network.

Key features of the study:

  • This report provides in-depth analysis of the Global Demineralized Bone Matrix Market, and provides market size (US$ Mn) and compound annual growth rate (CAGR%) for the forecast period (2021–2028), considering 2020 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends,  regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the Global Demineralized Bone Matrix Market based on the following parameters – Company Highlights, Products Portfolio, Key Highlights, Financial Performance, Strategies
  • Key companies covered as a part of this study include Medtronic Plc, Johnson & Johnson (DePuy Synthes), Exactech, Inc., HansBioMed, Xtant Medical, Stryker, Arthrex GmbH, RTI Surgical, Zimmer Biomet., and Straumann
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
  • The Global Demineralized Bone Matrix Market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the Global Demineralized Bone Matrix Market.

Detailed Segmentation:

  • Global Demineralized Bone Matrix Market, By Type :
    • Gel
    • Putty
    • Putty with Chips
    • Others
  • Global Demineralized Bone Matrix Market, By Applications:
    • Dental
    • Spine Surgery
    • Trauma Surgery
  • Global Demineralized Bone Matrix Market, By End User:
    • Hospitals
    • Specialty Clinics
    • Others
  • Global Demineralized Bone Matrix Market, By Region:
    • North America
      • By Type
        • Gel
        • Putty
        • Putty with Chips
        • Others
      •  By Applications
        • Dental
        • Spine Surgery
        • Trauma Surgery
      • By End User
        • Hospitals
        • Specialty Clinics
        • Others
      • By Country
        • U.S.
        • Canada
    • Latin America
      • By Type
        • Gel
        • Putty
        • Putty with Chips
        • Others
      •  By Applications
        • Dental
        • Spine Surgery
        • Trauma Surgery
      • By End User
        • Hospitals
        • Specialty Clinics
        • Others
      • By Country
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Type
        • Gel
        • Putty
        • Putty with Chips
        • Others
      •  By Applications
        • Dental
        • Spine Surgery
        • Trauma Surgery
      • By End User
        • Hospitals
        • Specialty Clinics
        • Others
      • By Country
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Type
        • Gel
        • Putty
        • Putty with Chips
        • Others
      •  By Applications
        • Dental
        • Spine Surgery
        • Trauma Surgery
      • By End User
        • Hospitals
        • Specialty Clinics
        • Others
      • By Country
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Type
        • Gel
        • Putty
        • Putty with Chips
        • Others
      •  By Applications
        • Dental
        • Spine Surgery
        • Trauma Surgery
      • By End User
        • Hospitals
        • Specialty Clinics
        • Others
      • By Country
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Type
        • Gel
        • Putty
        • Putty with Chips
        • Others
      •  By Applications
        • Dental
        • Spine Surgery
        • Trauma Surgery
      • By End User
        • Hospitals
        • Specialty Clinics
        • Others
      • By Country
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Medtronic Plc*
      • Company Highlights
      • Products Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • Johnson & Johnson (DePuy Synthes)
    • Exactech, Inc.
    • HansBioMed
    • Xtant Medical
    • Stryker
    • Arthrex GmbH
    • RTI Surgical
    • Zimmer Biomet
    • Straumann

 “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snapshot, By Type
      • Market Snapshot, By Application
      • Market Snapshot, By End user
      • Market Snapshot, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Opportunity
    • Impact Analysis
    • Pipeline Analysis
    • Regulatory Scenario
    • Market Trends
    • Key Developments
    • Epidemiology
    • PEST Analysis
    • Brand Analysis
  4. Global Demineralized Bone Matrix Market– Impact of Coronavirus (COVID-19) Pandemic
    • Impact on Supply and Demand
    • Impact on Procedures
    • Government Initiatives
  5. Global Demineralized Bone Matrix Market, By Type, 2017 – 2028, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2021 and 2028 (%)
      • Y-o-Y Growth Analysis, 2017 – 2028
      • Segment Trends
    • Gel
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 – 2028, (US$ Mn)
    • Putty
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 – 2028, (US$ Mn)
    • Putty with Chips
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 – 2028, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 – 2028, (US$ Million)
  6. Global Demineralized Bone Matrix Market, By Applications, 2017 – 2028, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2021 and 2028 (%)
      • Y-o-Y Growth Analysis, 2017 – 2028
      • Segment Trends
    • Dental
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 – 2028, (US$ Million)
    • Spine Surgery
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 – 2028, (US$ Million)
    • Trauma Surgery
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 – 2028, (US$ Million)
  7. Global Demineralized Bone Matrix Market, By End User, 2017 – 2028, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2021 and 2028 (%)
      • Y-o-Y Growth Analysis, 2017 – 2028
      • Segment Trends
    • Hospital
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 – 2028, (US$ Million)
    • Specialty Clinics
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 – 2028, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 – 2028, (US$ Million)
  8. Global Demineralized Bone Matrix Market, By Region, 2017 – 2028, (US$ Mn)
    • Introduction
      • Market Share Analysis, By Region, 2021 and 2028 (%)
      • Y-o-Y Growth Analysis, For Regions, 2017–2028
      • Regional Trends
    • North America
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Applications, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Countries, 2017 – 2028, (US$ Mn)
        • U.S.
        • Canada
    • Latin America
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Applications, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Countries, 2017 – 2028, (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Applications, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Countries, 2017 – 2028, (US$ Mn)
        • U.K.
        • Germany
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Applications, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Countries, 2017 – 2028, (US$ Mn)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Applications, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Countries, 2017 – 2028, (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, By Type, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Applications, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By End User, 2017 – 2028, (US$ Mn)
      • Market Size and Forecast, and Y-o-Y Growth, By Countries, 2017 – 2028, (US$ Mn)
        • North Africa
        • Central Africa
        • South Africa
  9. Competitive Landscape
    • Heat Map Analysis
    • Market Share Analysis
      • Medtronic Plc
        • Company Highlights
        • Product Portfolio
        • Key Highlights
        • Financial Performance
        • Strategies
      • Johnson & Johnson (DePuy Synthes)
        • Company Highlights
        • Product Portfolio
        • Key Highlights
        • Financial Performance
        • Strategies
      • Exactech, Inc.
        • Company Highlights
        • Product Portfolio
        • Key Highlights
        • Financial Performance
        • Strategies
      • HansBioMed
        • Company Highlights
        • Product Portfolio
        • Key Highlights
        • Financial Performance
        • Strategies
      • Xtant Medical
        • Company Highlights
        • Product Portfolio
        • Key Highlights
        • Financial Performance
        • Strategies
      • Stryker
        • Company Highlights
        • Product Portfolio
        • Key Highlights
        • Financial Performance
        • Strategies
      • Arthrex GmbH
        • Company Highlights
        • Product Portfolio
        • Key Highlights
        • Financial Performance
        • Strategies
      • RTI Surgical
        • Company Highlights
        • Product Portfolio
        • Key Highlights
        • Financial Performance
        • Strategies
      • Zimmer Biomet
        • Company Highlights
        • Product Portfolio
        • Key Highlights
        • Financial Performance
        • Strategies
      • Straumann
        • Company Highlights
        • Product Portfolio
        • Key Highlights
        • Financial Performance
        • Strategies
    • Analyst Views
  10. Section
    • Research Methodology
    • About us

*Browse 27 market data tables and 31 figures on "Global Demineralized Bone Matrix Market” - Global forecast to 2028

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

Subscribe Newsletter

Kindly Subscribe for our latest news & articles.