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Phase-Xs | Biologics & Biosimilars | Coherent Market Insights

Hemoglobinopathy Market – Insights

Hemoglobinopathy a group of hereditary blood disorders involving an abnormality in the structure of hemoglobin. . These disorders include both sickle cell disease (SCD) and thalassemia. Common symptoms of the condition include, severe pain, shortness of breath, enlarged spleen, and growth problems in children.

The global hemoglobinopathy market is estimated to account for US$ 523.4 Mn in terms of value in 2019 and is expected to reach US$ 1,001.6 Mn by the end of 2027.

Global Hemoglobinopathy Market: Drivers

Increasing prevalence of sickle cell disease is expected to propel growth of the global hemoglobinopathy market over the forecast period. For instance, the study, ‘Prevalence of sickle cell disease and sickle cell trait among children admitted to Al Fashir Teaching Hospital North Darfur State, Sudan’, published in October 2019, reported a prevalence of 59 for sickle cell disease.

Moreover, government initiatives for the management and treatment of hemoglobinopathies is also expected to aid in growth of the market. For instance, in August 2018, the Ministry of Health and Family Welfare, Government of India, released the new draft policy for hemoglobinopathies in India.

Europe region held dominant position in the global hemoglobinopathy market in 2018, accounting for 32.6% share in terms of value, followed by North America.

Hemoglobinopathy Treatment  | Coherent Market Insights

Global Hemoglobinopathy Market: Restraints

Failing clinical trials for the treatment of sickle cell anemia are expected to hinder the market growth. For instance, in August 2019, Pfizer Inc. announced that the Phase III Rivipansel pivotal study, to evaluate the efficacy and safety of rivipansel in patients aged six and older with sickle cell disease, failed to achieve its primary or key secondary efficacy endpoints.

Moreover, lack of a permanent cure for hemoglobinopathy disorders is also expected to limit the market growth. Most treatment options available focus on reducing symptoms of the disorders and the only reliable treatment available is bone marrow transplant, which is a very complex and expensive procedure and is also associated with some side effects.

Global Hemoglobinopathy Market: Opportunities

The epidemiological data for hemoglobinopathies is incomplete and the precise burden of these disorders is unknown in several developing economies. Therefore, identifying the socio-economic burden of these disorders is expected to offer lucrative growth opportunities for players in the market.

Moreover, awareness and education programs in the community, schools, and colleges regarding hemoglobinopathies is also expected to aid in growth of the market.

Hemoglobinopathy Treatment  | Coherent Market Insights

Routine Red Blood Cell (RBC) count segment in the global hemoglobinopathy market was valued at US$ 161.4 Mn in 2019 and is expected to reach US$ 277.9 Mn by 2027 at a CAGR of 7.4% during the forecast period.

Market Trends/Key Takeaways

Hematopoietic stem cell transplantation is the only validated curative treatment of sickle cell disease. Although hematopoietic stem cell transplantation reverses accelerated coagulation reactions in children with sickle cell disease, it is necessary to assess the clinical influence and the underlying mechanisms of the changes induced by hematopoietic stem cell transplantation on coagulation in sickle cell disease.

Research and development of novel technologies that may aid in treatment of sickle cell anemia is expected to boost the market growth. For instance, in July 2019, researchers from Florida Atlantic University, in a study published in the journal ACS Sensors, demonstrated a microfluidic impedance assay that can monitor the dynamic cell sickling and unsickling processes.

Hemoglobinopathy Treatment  | Coherent Market Insights

Global Hemoglobinopathy Market: Competitive Landscape 

Major players operating in the global hemoglobinopathy market include, Abbott Diagnostics, Bio-Rad Laboratories, Inc., Danaher Corp., ReachBio Research Labs, Mindray Medical International Ltd., Nexcelom Bioscience LLC, Nihon Kohden Europe Ltd., PerkinElmer Inc., Siemens Healthineers, and Sysmex Europe GmbH

Global Hemoglobinopathy Market: Key Developments  

Major players in the market are focused on launching platforms to screen drugs for the treatment of sickle cell disease. For instance, in August 2019, ReachBio Research Labs started offering a drug screening platform to assess fetal hemoglobin protein induction in drug candidates for the treatment of sickle cell disease.

Major players in the market are also focused on conducting clinical trials related to hemoglobinopathies. For instance, in September 2018, AstraZeneca initiated its clinical trial for Ticagrelor, a drug for the treatment of sickle cell disease.

Hemoglobinopathy includes a range of disorders, which occur due to altered structure of hemoglobin. Hemoglobin is present in the red blood cells that transports oxygen from the lung to the body. Hemoglobinopathy disorder are inherited and are passed on from one generation to another. It is further classified into two categories – 1. Thalassemia Syndrome 2. Structural Hemoglobin Variants. Thalassemia syndrome includes disorder related to synthesis defect. The synthesis defect of alpha globin gives rise to alpha thalassemia and defect in beta globin give rise to beta thalassemia. The structural hemoglobin variants occur due to alteration of alpha and beta chains that causes defect in structure.

Restraints of the Global Hemoglobinopathy Market

High costs, and difficulties associated with diagnosis of hemoglobinopathies such as lack of proper knowledge, and lack of skilled professionals is expected to restrain growth of the market up to certain extent.

Key features of the study:

  • This report provides in-depth analysis of the global hemoglobinopathy market and provides market size (US$ Million) and compound annual growth rate (CAGR %) for the forecast period (2019–2027), considering 2018, as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, regional outlook, and competitive strategy adopted by leading players
  • It profiles leading players in the global hemoglobinopathy market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments, strategies, and future plans
  • Key companies covered as a part of this study include Abbott Diagnostics, Bio-Rad Laboratories, Inc., Danaher Corp., ReachBio Research Labs, Mindray Medical International Ltd., Nexcelom Bioscience LLC, Nihon Kohden Europe Ltd., PerkinElmer Inc., Siemens Healthineers, and Sysmex Europe GmbH
  • Insights from this report would allow marketers and the management authorities of companies to make informed decision regarding future product launches, technology up-gradation, market expansion, and marketing tactics
  • The global hemoglobinopathy market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts.
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the market.

Detailed Segmentation

  • Global Hemoglobinopathy Market, By Test Type:
    • Routine Red Blood Cell (RBC) count
    • Genetic Testing
    • Hemoglobin by high performance liquid chromatography
    • Hemoglobin isoelectric focusing ( Hb IEF)
    • Hemoglobin electrophoresis (Hb ELP)
    • Hemoglobin solubility test
  • Global Hemoglobinopathy Market, By Indication:
    • Sickle Cell Disease
    • Beta Thalassemia
    • Alpha Thalassemia
  • Global Hemoglobinopathy Market, By End User:
    • Hospitals
    • Diagnostic Laboratories
    • Clinics
  • Global Hemoglobinopathy Market, By Geography:
    • North America
      • By Test Type
        • Routine Red Blood Cell (RBC) count
        • Genetic Testing
        • Hemoglobin by high performance liquid chromatography
        • Hemoglobin isoelectric focusing ( Hb IEF)
        • Hemoglobin electrophoresis (Hb ELP)
        • Hemoglobin solubility test
      • By Indication
        • Sickle Cell Disease
        • Beta Thalassemia
        • Alpha Thalassemia
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Clinics
      • By Country:
        • U.S.
        • Canada
    • Europe
      • By Test Type
        • Routine Red Blood Cell (RBC) count
        • Genetic Testing
        • Hemoglobin by high performance liquid chromatography
        • Hemoglobin isoelectric focusing ( Hb IEF)
        • Hemoglobin electrophoresis (Hb ELP)
        • Hemoglobin solubility test
      • By Indication
        • Sickle Cell Disease
        • Beta Thalassemia
        • Alpha Thalassemia
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Clinics
      • By Country:
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Test Type
        • Routine Red Blood Cell (RBC) count
        • Genetic Testing
        • Hemoglobin by high performance liquid chromatography
        • Hemoglobin isoelectric focusing ( Hb IEF)
        • Hemoglobin electrophoresis (Hb ELP)
        • Hemoglobin solubility test
      • By Indication
        • Sickle Cell Disease
        • Beta Thalassemia
        • Alpha Thalassemia
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Clinics
      • By Country:
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • By Test Type
        • Routine Red Blood Cell (RBC) count
        • Genetic Testing
        • Hemoglobin by high performance liquid chromatography
        • Hemoglobin isoelectric focusing ( Hb IEF)
        • Hemoglobin electrophoresis (Hb ELP)
        • Hemoglobin solubility test
      • By Indication
        • Sickle Cell Disease
        • Beta Thalassemia
        • Alpha Thalassemia
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Clinics
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Middle East:
      • By Test Type
        • Routine Red Blood Cell (RBC) count
        • Genetic Testing
        • Hemoglobin by high performance liquid chromatography
        • Hemoglobin isoelectric focusing ( Hb IEF)
        • Hemoglobin electrophoresis (Hb ELP)
        • Hemoglobin solubility test
      • By Indication
        • Sickle Cell Disease
        • Beta Thalassemia
        • Alpha Thalassemia
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Clinics
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Test Type
        • Routine Red Blood Cell (RBC) count
        • Genetic Testing
        • Hemoglobin by high performance liquid chromatography
        • Hemoglobin isoelectric focusing ( Hb IEF)
        • Hemoglobin electrophoresis (Hb ELP)
        • Hemoglobin solubility test
      • By Indication
        • Sickle Cell Disease
        • Beta Thalassemia
        • Alpha Thalassemia
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Clinics
      • By Country/Region:
        • Central Africa
        • South Africa
        • North Africa
  • Company Profiles
    • Abbott Diagnostics *
      • Company Overview
      • Test Portfolio
      • Financial Performance
      • Key Strategies
      • Recent Developments
    • Bio-Rad Laboratories, Inc.
    • Danaher Corp.
    • ReachBio Research Labs
    • Mindray Medical International Ltd.
    • Nexcelom Bioscience LLC
    • Nihon Kohden Europe Ltd.
    • PerkinElmer Inc.
    • Siemens Healthineers
    • Sysmex Europe GmbH

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Test Type
      • Market Snippet, By Indication
      • Market Snippet, By End User
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Key Developments
    • Regulatory Scenario
    • PEST Analysis
  4. Global Hemoglobinopathy Market, By Test Type, 2019 – 2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
    • Routine Red Blood Cell (RBC) count
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
      • Segment Trends
    • Genet~ic Testing
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
      • Segment Trends
    • Hemoglobin by high performance liquid chromatography
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
      • Segment Trends
    • Hemoglobin isoelectric focusing ( Hb IEF)
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
      • Segment Trends
    • Hemoglobin electrophoresis (Hb ELP)
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
      • Segment Trends
    • Hemoglobin solubility test
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
      • Segment Trends
  5. Global Hemoglobinopathy Market, By Indications, 2019 – 2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
    • Sickle Cell Disease
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Beta Thalassemia
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Alpha Thalassemia
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
  6. Global Hemoglobinopathy Market, By End User, 2019 – 2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
    • Hospitals
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Diagnostic Laboratories
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Clinics
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
  7. Global Hemoglobinopathy Market, By Regions, 2019 – 2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
      • Segment Trends
    • North America
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • U.S.
        • Canada
    • Europe
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Middle East
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
        • North Africa
        • Central Africa
        • South Africa
  8. Competitive Landscape
    • Company Profiles
      • Abbott Diagnostics
        • Company Overview
        • Test Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
      • Bio-Rad Laboratories, Inc.
        • Company Overview
        • Test Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
      • Danaher Corp.
        • Company Overview
        • Test Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
      • ReachBio Research Labs
        • Company Overview
        • Test Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
      • Mindray Medical International Ltd.
        • Company Overview
        • Test Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
      • Nexcelom Bioscience LLC
        • Company Overview
        • Test Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
      • Nihon Kohden Europe Ltd.
        • Company Overview
        • Test Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
      • PerkinElmer Inc.
        • Company Overview
        • Test Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
      • Siemens Healthineers
        • Company Overview
        • Test Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
      • Sysmex Europe GmbH
        • Company Overview
        • Test Portfolio
        • Key Developments
        • Financial Performance
        • Strategies
  9. Section
    • References
    • Research Methodology
    • About us and Sales Contact

*Browse 31 market data tables and 27 figures on “Hemoglobinopathy Market – Global forecast to 2027.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users