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Phase-Xs | Biologics & Biosimilars | Coherent Market Insights

In vitro toxicology testing is used to examine the toxic properties of compounds and mixtures on cultured bacteria or mammalian cells. Absorption, distribution, metabolism, and excretion (ADME), and toxicological profiling plays a major role in drug development. It focuses on obtaining an early estimate of human pharmacokinetic and metabolic profiles.

Statistics:

The global in vitro toxicity testing market is estimated to account for US$ 14,940.2 Mn in terms of value by the end of 2027.

Global In Vitro Toxicity Testing Market: Drivers

Opposition to animal testing is expected to propel growth of the global in vitro toxicity testing market over the forecast period. Concerns over animal experiments have been raised in the field of toxicity testing, owing to issues such as difference between various test animals and the resultant effect of toxicants on the animals. Various animal welfare associations and organizations have also increased their efforts towards elimination of toxicity testing on animals. Such scenario has led to increasing adoption of in vitro toxicity testing.

Moreover, various advantages of in vitro toxicity testing are also expected to aid in growth of the market. In vitro toxicity testing eliminates the use of animals from the testing procedures. It also covers a wide range of toxicity pathways and thus helps in convenient testing. This method also gives sufficient detection of toxic effects on the organisms at very low concentration, which is otherwise not possible in animal testing.

Statistics:

North America held dominant position in the global in vitro toxicity testing market in 2019, accounting for 32.9% share in terms of value, followed by Europe and Asia Pacific, respectively

Figure 1: Global In Vitro Toxicity Testing Market Share (%), in Terms of Value, By Region, 2019

In Vitro Toxicity Testing  | Coherent Market Insights

Global In Vitro Toxicity Testing Market: Restraints

Questionable predictive power of in vitro toxicity testing is expected to hinder growth of the market. As compared to the conventional animal testing, in vitro toxicity testing has not turned out to be a more reliable predictor. Although in vitro cytotoxicity assays have been used by scientists in drug testing, it has not been consistently applied to the decision making involved in early drug development.

Moreover, the influence of nanomaterial properties on the outcome of in vitro toxicity testing through assay interference is also expected to limit growth of the market. Such interference can lead to false positive or false negative results.

 Global In Vitro Toxicity Testing Market: Opportunities 

Strict regulations banning animal testing are expected to offer lucrative growth opportunities for players in the global in vitro toxicity market. For instance, in January 2020, the state governments of California, Nevada, and Illinois banned the sale or import of animal-tested cosmetics.

Moreover, increasing demand for personal care products is also expected to aid in growth of the market. For instance, according to India Brand Equity Foundation, the beauty, cosmetic and grooming market in India is expected to reach US$ 20 billion by 2025.

Statistics:

The global in vitro toxicity testing market was valued at US$ 4,745.9 Mn in 2019 and is forecast to reach a value of US$ 14,940.2 Mn by 2027 at a CAGR of 15.4% between 2020 and 2027.

Figure 2: Global In Vitro Toxicity Testing Market Value (US$ Mn), in Terms of Value, 2016 - 2027

In Vitro Toxicity Testing  | Coherent Market Insights

Market Trends/Key Takeaways

Major regulatory bodies are focused on providing guidelines for in vitro toxicity testing. For instance, in January 2020, the U.S. FDA finalized its In Vitro Guidance for the pharmaceutical industry in order to help drug developers plan and evaluate studies to determine the drug-drug interaction potential of an investigational drug product.

The market is witnessing increasing adoption of Next Generation Sequencing (NGS) as an alternative or supplement to conventional in vivo or in vitro testing methods for biologics testing. For instance, in January 2020, PathoQuest, a strategic partner of Charles River Laboratories International Inc., received its GLP certificate for advanced NGS viral safety testing from the French National Agency for Medicine and Health Products Safety.

Global In Vitro Toxicity Testing Market: Competitive Landscape

Major players operating in the global in vitro toxicity testing market include, Bio-Rad Laboratories, Inc., Cyprotex, Charles River Laboratories International Inc., and Covance Inc.

Global In Vitro Toxicity Testing Market: Key Developments

Major players in the market are focused on adopting collaboration and partnership strategies to expand their product portfolio. For instance, in January 2019, LabCorp, along with its subsidiary Covance Inc., partnered with GENFIT, a biopharmaceutical company focused on R&D in liver diseases, for access to non-alcoholic steatohepatitis liver diagnostic test for the clinical research market.

In Vitro Toxicity Testing helps in assessing the toxic properties of compounds and mixtures on cultured bacteria or mammalian cells and provides human pharmacokinetic and metabolic profiles. In vitro toxicity testing eliminates the use of animals from the testing procedures. Increasing prevalence of chronic disorders and rise in pandemic disease during the forecasted period is anticipated to assist the growth of the market.

Furthermore, major players in the market are focused on adopting expansion strategies such as mergers & acquisitions along strategic collaboration and partnerships to increase their product portfolio during the forecast period.

Key features of the study:

  • This report provides in-depth analysis of the In Vitro Toxicity Testing market  and provides market size (US$ million) and compound annual growth rate (CAGR %) for the forecast period (2020–2027), considering 2019 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends,  regional outlook, and competitive strategy adopted by key players
  • It profiles key players in the global In Vitro Toxicity Testing market  based on the following parameters – company overview, financial performance, product portfolio, market presence, distribution strategies, key developments, strategies, and future plans
  • Key companies covered as a part of this study include, Bio-Rad Laboratories, Inc., Cyprotex, Charles River Laboratories International Inc., and Covance Inc.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, technology up-gradation, market expansion, and marketing tactics
  • The global In Vitro Toxicity Testing market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global In Vitro Toxicity Testing market

Detailed Segmentation:

  • In Vitro Toxicity Testing Market, By Type:
      • Absorption
      • Toxic Substances
      • Dose
  • In Vitro Toxicity Testing Market, By End User:
      • Cosmetics And Household Products
      • Pharmaceutical Industry
      • Food Industry
      • Chemicals Industry
  • In Vitro Toxicity Testing Market, By Region:
    • North America
      • By Type:
        • Absorption
        • Toxic Substances
        • Dose
      • By End Use
        • Cosmetics And Household Products
        • Pharmaceutical Industry
        • Food Industry
        • Chemicals Industry
      • By Country:
        • U.S.
        • Canada
    • Latin America
      • By Type:
        • Absorption
        • Toxic Substances
        • Dose
      • By End Use
        • Cosmetics And Household Products
        • Pharmaceutical Industry
        • Food Industry
        • Chemicals Industry
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Type:
        • Absorption
        • Toxic Substances
        • Dose
      • By End Use
        • Cosmetics And Household Products
        • Pharmaceutical Industry
        • Food Industry
        • Chemicals Industry
      • By Country:
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Type:
        • Absorption
        • Toxic Substances
        • Dose
      • By End Use
        • Cosmetics And Household Products
        • Pharmaceutical Industry
        • Food Industry
        • Chemicals Industry
      • By Country:
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Type:
        • Absorption
        • Toxic Substances
        • Dose
      • By End Use
        • Cosmetics And Household Products
        • Pharmaceutical Industry
        • Food Industry
        • Chemicals Industry
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Type:
        • Absorption
        • Toxic Substances
        • Dose
      • By End Use
        • Cosmetics And Household Products
        • Pharmaceutical Industry
        • Food Industry
        • Chemicals Industry
      • By Country:
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Bio-Rad Laboratories, Inc. *
      • Company Overview
      • Product Portfolio
      • Key Highlights
      • Financial Overview
      • Strategies
    • Cyprotex
    • Charles River Laboratories International Inc.
    • Covance Inc.
  •  “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Type
      • Market Snippet, By End Use
      • Market Snippet, By Region
      • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Key Highlights
    • Product launch
    • PEST Analysis
    • Technological Advancements
    • Regulatory Scenario
    • Mergers and Acquisitions
  4. In Vitro Toxicity Testing Market, By Type, 2019 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Absorption
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Toxic Substances
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Dose
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
  5. In Vitro Toxicity Testing Market, By End Use, 2019 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Cosmetics And Household Products
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Pharmaceutical Industry
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Food Industry
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
    • Chemicals Industry
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
  6. In Vitro Toxicity Testing Market, By Region, 2019 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, By Region, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, For Regions, 2017–2026
    • North America
      • Market Size and Forecast, By Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By End Use, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • U.S.
        • Canada
    • Latin America
      • Market Size and Forecast, By Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By End Use, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Market Size and Forecast, By Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By End Use, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By End Use, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of APAC
    • Middle East
      • Market Size and Forecast, By Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By End Use, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Market Size and Forecast, By Type, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By End Use, 2016 – 2027, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Mn)
        • South Africa
        • Central Africa
        • North Africa
  7. Competitive Landscape
    • Company Profiles
      • Bio-Rad Laboratories, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Cyprotex
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Charles River Laboratories International Inc.
        • Company Overview
        • Product Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
  8. Section
    • References
    • Research Methodology
    • About us and Sales Contact

*Browse 18 market data tables and 12 figures on “In Vitro Toxicity Testing Market - Global forecast to 2027”.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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