Personalized Cell Therapy Market - Insights

Individualized treatment for various diseases such as cancer and autoimmune diseases by injecting living cells into a patient’s body is known as personalized cell therapy. It has various applications such as platelet transfusions, bone marrow transplantation, whole blood transfusions, packed red cell transfusions, and organ transplantation. It is used to treat various chronic conditions such as Parkinson’s disease and amyotrophic lateral sclerosis (neurological diseases), spinal cord injuries, diabetes, and cancer.

The global personalized cell therapy market was valued at US$ 8,046.30 million in 2018 and is expected to exhibit a CAGR of 23.5% during the forecast period (2019 – 2027).

Figure 1. Global Personalized Cell Therapy Market Size Analysis (US$ Mn) and Forecast and Absolute $ Opportunity

Personalized Cell Therapy  | Coherent Market Insights

Source: Coherent Market Insights Analysis (2019)

Increased economic burden due to neurological disorders is expected to fuel the global personalized cell therapy market growth

There are several studies conducted on stem cell or personalized cell therapy candidates to treat neurological disorder and spinal cord injury. For instance, in September 2016, MAPFRE Foundation, announced its first clinical trial results of personalized cell therapy in patients with complete and chronic spinal cord injury. The study was conducted to implant mesenchymal stem cells, which can create different types of tissue to treat spinal cord injury.

Increasing development of personalized cell therapy products along with high prevalence of lifestyle diseases is driving the global personalized cell therapy market growth

Rising prevalence of chronic diseases and increasing incidence of cancer is expected to fuel growth of the global personalized cell therapy market over the forecast period. For instance, according to the National Cancer Institute (NCI), in 2016, there were an estimated 15.5 million cancer cases that have been reported in the U.S. Moreover, according to NCI, in 2017, around 15,270 children and adolescents of age group of 0 to 19 were diagnosed with cancer in the U.S. Furthermore, according to the International Diabetes Federation (IDF), in 2017, over 425 million adults suffered from diabetes globally, and this is expected to reach 629 million by 2045.

Manufacturers are conducting large number clinical trials, in order to develop novel personalized cell therapies targeting chronic diseases such as cancer, diabetes, and other autoimmune diseases. For instance, in April 2019, Orgenesis Inc. a developer, and service provider of advanced cell therapies received Institutional Review Board (IRB) approval to collect liver biopsies from patients at Rambam Medical Center located in Haifa, Israel. The sample will be collected to confirm the safety and efficacy of liver cells for personalized cell replacement therapy in the patients with insulin-dependent diabetes resulting from total or partial pancreatectomy. Thus, increasing research studies is expected to drive the global personalized cell therapy market growth.

Global Personalized Cell Therapy Market- Regional Analysis

Regional segmentation of the global personalized cell therapy market comprises North America, Latin America, Europe, Asia Pacific, Middle East, and Africa.

Better healthcare amenities along with high adoption of new technology for the treatment of chronic disease such as cancer, diabetes, renal dysfunction, and other autoimmune diseases in the developed economies is expected to boost overall sales of personalized cell therapy products, which in turn expected to drive the personalized cell therapy market growth over the forecast period. Moreover, number of research institutes in North America region are engaged in development of novel personalized cell therapy for various indications. For instance, in June 2019, University of Wisconsin’s (UW) Program for Advanced Cell Therapy (PACT) launched First-in-U.S. Cell Therapy Trial to treat a viral infection faced by kidney and/or pancreas transplant recipients.

Increasing approval for personalized cell therapy in Asia Pacific region is expected to boost the personalized cell therapy market growth. For instance, in February 2019, Ministry of Health, Labour and Welfare, Japan, approved production and sales of a CAR T-cell therapy, Kymriah therapy developed by Swiss pharmaceutical (Novartis), for treatment of the patients (young) with  leukemia. Moreover in February 2019, Ministry of Health, Labour and Welfare, Japan, approved human induced pluripotent stem cells therapy trial to treat spinal cord injury.  The trial was initiated by the researchers of Keio University in 2019.

Expansion of manufacturing facility for the increased production of personalized cell therapy in the U.K. is anticipated to witness the personalized cell therapy market growth in European region. For instance, in 2018, according to the Cell and Gene Therapy (CGT) Catapult report on U.K.’s cell and gene therapy industry, the U.K. has accounted for 60% increase in manufacturing space for personalized cell therapy developing, licensed by the U.K.’s Medicines and Healthcare products Regulatory Agency (MHRA) and meeting Good Manufacturing Practice (GMP) standards

Figure 2. Global Personalized Cell Therapy Market Value Analysis, By Region - 2018

Personalized Cell Therapy  | Coherent Market Insights

Source: Coherent Market Insights (2019)

Market players operating in the global personalized cell therapy market include Cytori Therapeutics Inc., Bellicum Pharmaceuticals, Inc., Saneron CCEL Therapeutics, Inc., MolMed S.p.A., Vericel Corporation, Novartis AG, Gilead Sciences, Inc., Celgene Corporation, Bluebird Bio, Inc. and Aurora Biopharma Inc.

The patient-tailored therapies for the treatment of various diseases is known as personalized cell therapy. The personalized cell therapy is based on genomic profile, and disease prevalence/severity and the drug developed by this therapy target the patients, who matches the specific disease physiopathology and/or patient characteristics. The personalized cell therapy is mainly developed for the treatment of high unmet need disease such as cancer, autoimmune disease, cardiovascular, neurologic, and inflammatory disease. Personalized cell therapy have application in platelet transfusions, packed red cell transfusions, bone marrow transplantation, and organ transplantation.

Personalized Cell Therapy Market Dynamics

Personalized cell therapy aids in accurate diagnosis of the disease and active monitoring of the treatment response, and disease progression. This allows for early detection of diseases at molecular level and allows physician to prepare treatment regime for the specific patient requirement. This helps the patient to recover at a significant pace and also helps avoid any major side effects, as individualized cell therapy is based on patient’s genomics.

Introduction of innovative personalized cell therapy and large number of cell therapies in pipeline by key players is expected to boost the market growth over the forecast period. For instance, in August 2017, the University of Pennsylvania and Children’s Hospital of Philadelphia (CHOP) received the U.S. Food and Drug Administration (FDA) approval for its newly developed personalized cellular therapy indicated for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

Key features of the study:

  • This report provides in-depth analysis of the global personalized cell therapy market, market size (US$ Mn), and compound annual growth rate (CAGR %) over the forecast period (2019–2027), considering 2018, as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new technology launches or approvals, market trends, regional outlook, and competitive strategies adopted by leading players
  • It profiles leading players in the global personalized cell therapy market based on the following parameters – company overview, financial performance, technology portfolio, geographical presence, distribution strategies, key developments, and strategies
  • Key players covered as a part of this study include Cytori Therapeutics Inc., Bellicum Pharmaceuticals, Inc., Saneron CCEL Therapeutics, Inc., MolMed S.p.A., Vericel Corporation, Novartis AG, Gilead Sciences, Inc., Celgene Corporation, Bluebird Bio, Inc. and Aurora Biopharma Inc.
  • Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to future technology launches, governmental initiatives, technological upgradation, market expansion, and marketing tactics
  • The global personalized cell therapy market report caters to various stakeholders in this market, including investors, technology manufacturers, distributors, and suppliers for global personalized cell therapy market, research and consulting firms, new entrants, and financial analysts

Detailed Segmentation:

  • Global Personalized Cell Therapy Market, By Cell Type:
    • Lymphocytes
    • Mesenchymal Stem Cell
    • Hematopoietic  Stem Cell
    • Others
  • Global Personalized Cell Therapy Market, By Therapeutic Area:
    • Cardiovascular Diseases
    • Neurological Disorders
    • Inflammatory Diseases
    • Diabetes
    • Cancer
  • Global Personalized Cell Therapy Market, By Region:
    • North America
      • North America Personalized Cell Therapy Market, By Cell Type:
        • Lymphocytes
        • Mesenchymal Stem Cell
        • Hematopoietic  Stem Cell
        • Others
      • North America Personalized Cell Therapy Market, By Therapeutic Area:
        • Cardiovascular Diseases
        • Neurological Disorders
        • Inflammatory Diseases
        • Diabetes
        • Cancer
      • North America Personalized Cell Therapy Market, By Country:
        • U.S.
        • Canada
    • Europe
      • Europe Personalized Cell Therapy Market, By Cell Type:
        • Lymphocytes
        • Mesenchymal Stem Cell
        • Hematopoietic  Stem Cell
        • Others
      • Europe Personalized Cell Therapy Market, By Therapeutic Area:
        • Cardiovascular Diseases
        • Neurological Disorders
        • Inflammatory Diseases
        • Diabetes
        • Cancer
      • Europe Personalized Cell Therapy Market, By Country:
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Asia Pacific Personalized Cell Therapy Market, By Cell Type:
        • Lymphocytes
        • Mesenchymal Stem Cell
        • Hematopoietic  Stem Cell
        • Others
      • Asia Pacific Personalized Cell Therapy Market, By Therapeutic Area:
        • Cardiovascular Diseases
        • Neurological Disorders
        • Inflammatory Diseases
        • Diabetes
        • Cancer
      • Asia Pacific Personalized Cell Therapy Market, By Country:
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Latin America
      • Latin America Personalized Cell Therapy Market, By Cell Type:
        • Lymphocytes
        • Mesenchymal Stem Cell
        • Hematopoietic  Stem Cell
        • Others
      • Latin America Personalized Cell Therapy Market, By Therapeutic Area:
        • Cardiovascular Diseases
        • Neurological Disorders
        • Inflammatory Diseases
        • Diabetes
        • Cancer
      • Latin America Personalized Cell Therapy Market, By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Middle East
      • Middle East Personalized Cell Therapy Market, By Cell Type:
        • Lymphocytes
        • Mesenchymal Stem Cell
        • Hematopoietic  Stem Cell
        • Others
      • Middle East Personalized Cell Therapy Market, By Therapeutic Area:
        • Cardiovascular Diseases
        • Neurological Disorders
        • Inflammatory Diseases
        • Diabetes
        • Cancer
      • Middle East Personalized Cell Therapy Market, By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Africa Personalized Cell Therapy Market, By Cell Type:
        • Lymphocytes
        • Mesenchymal Stem Cell
        • Hematopoietic  Stem Cell
        • Others
      • Africa Personalized Cell Therapy Market, By Therapeutic Area:
        • Cardiovascular Diseases
        • Neurological Disorders
        • Inflammatory Diseases
        • Diabetes
        • Cancer
      • Africa Personalized Cell Therapy Market, By Country/Region:
        • North Africa
        • Central Africa
        • South Africa
  • Company Profiles
    • Cytori Therapeutics Inc. *
      • Company Overview
      • Product Portfolio
      • Strategies Presence
      • Key Developments
    • Bellicum Pharmaceuticals, Inc.
    • Saneron CCEL Therapeutics, Inc.
    • MolMed S.p.A.
    • Vericel Corporation
    • Novartis AG
    • Gilead Sciences, Inc.
    • Celgene Corporation
    • Bluebird Bio, Inc.
    • Aurora Biopharma Inc.

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Cell Type
      • Market Snippet, By Therapeutic Area
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers, Challenges, and Recommendations
      • Regulatory Scenario
      • Market Trends
      • Market Opportunities
      • Merger and Acquisitions
      • Key Developments
      • Approved Products and Industry Disruptive Force (CAR-T Cell Therapy)
  4. Global Personalized Cell Therapy Market, By Cell Type, 2016 - 2027 (US$ Million)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 - 2027
      • Segment Trends
    • Lymphocytes
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Mesenchymal Stem Cell
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Hematopoietic Stem Cell
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
  5. Global Personalized Cell Therapy Market, By Therapeutic Area, 2016 - 2027 (US$ Million)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 - 2027
      • Segment Trends
    • Cardiovascular Diseases
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Neurological Disorders
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Inflammatory Diseases
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Diabetes
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
    • Cancer
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2027, (US$ Million)
  6. Global Personalized Cell Therapy Market, By Region, 2016 - 2027 (US$ Million)
    • Introduction
      • Market Share Analysis, By Geography, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Regional Trends
      • Regional Attractiveness Index
    • North America
      • Introduction
      • Market Share Analysis, By Cell Type, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Therapeutic Area, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Country, 2016 - 2027 (US$ Million)
        • U.S.
        • Canada
    • Europe
      • Introduction
      • Market Share Analysis, By Cell Type, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Therapeutic Area, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Country, 2016 - 2027 (US$ Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Introduction
      • Market Share Analysis, By Cell Type, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Therapeutic Area, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Country, 2016 - 2027 (US$ Million)
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Introduction
      • Market Share Analysis, By Cell Type, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Therapeutic Area, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Country, 2016 - 2027 (US$ Million)
        • Brazil
        • Argentina
        • Rest of Latin America
    • Middle East
      • Introduction
      • Market Share Analysis, By Cell Type, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Therapeutic Area2016 - 2027 (US$ Million)
      • Market Share Analysis, By Country, 2016 - 2027 (US$ Million)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Introduction
      • Market Share Analysis, By Cell Type, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Therapeutic Area, 2016 - 2027 (US$ Million)
      • Market Share Analysis, By Country/Region, 2016 - 2027 (US$ Million)
        • North Africa
        • Central Africa
        • South Africa
  7. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • Cytori Therapeutics Inc.
        • Company Highlights
        • Product Portfolio
        • Strategic Presence
        • Key Developments
        • Strategies
      • Bellicum Pharmaceuticals, Inc.
        • Company Highlights
        • Product Portfolio
        • Strategic Presence
        • Key Developments
        • Strategies
      • Saneron CCEL Therapeutics, Inc.
        • Company Highlights
        • Product Portfolio
        • Strategic Presence
        • Key Developments
        • Strategies
      • MolMed S.p.A.
        • Company Highlights
        • Product Portfolio
        • Strategic Presence
        • Key Developments
        • Strategies
      • Vericel Corporation
        • Company Highlights
        • Product Portfolio
        • Strategic Presence
        • Key Developments
        • Strategies
      • Novartis AG
        • Company Highlights
        • Product Portfolio
        • Strategic Presence
        • Key Developments
        • Strategies
      • Gilead Sciences, Inc.
        • Company Highlights
        • Product Portfolio
        • Strategic Presence
        • Key Developments
        • Strategies
      • Celgene Corporation
        • Company Highlights
        • Product Portfolio
        • Strategic Presence
        • Key Developments
        • Strategies
      • Bluebird Bio, Inc.
        • Company Highlights
        • Product Portfolio
        • Strategic Presence
        • Key Developments
        • Strategies
      • Aurora Biopharma Inc.
        • Company Highlights
        • Product Portfolio
        • Strategic Presence
        • Key Developments
        • Strategies
    • Analyst Views
  8. Section
    • Research Methodology
    • About us and Services

*Browse 23 market data tables and 19 figures on "Personalized Cell Therapy Market - Global forecast to 2027”.  

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users