Fructose Consumption Might Augment Intestinal Inflammation, Study Suggests

Jan, 2021 - by CMI

According to a new study led by the researchers of Stony Brook University have suggested that consumption of fructose may worsen the inflammatory bowel diseases (IBD). It is evident there is increasing incidence of IBD, across the globe. Moreover, according to the Centers for Disease Control and Prevention (CDC), around three million U.S. populace are reported to be diagnosed with IBD each year, which increased from one million in the late 1990s. Researchers also informed that rising preference and consumption of a Western diet, which includes fructose further results in increasing rates of obesity and diabetes. They also noted that IBD may be an added disease that is aggravated due to intake of fructose.

Montrose from Stony Brook University Cancer Center stated, “The increasing incidence of IBD parallels higher levels of fructose consumption in the United States and other countries. Our findings provide evidence of a direct link between dietary fructose and IBD and support the concept that high consumption of fructose could worsen disease in people with IBD. This is important because it has the potential to provide guidance on diet choices for IBD patients, something that is currently lacking.”

In this study, researchers considered three mouse models with inflammatory bowel disease and were allowed to feed on high amounts of fructose. High intake of fructose deteriorated the colonic inflammation in mice and exhibited notable effects in their gut bacteria. Researchers observed that high fructose diet results in detrimental effects in microbiota, which alters composition, distribution, and metabolic function of resident enteric gut microbiota.