Cathepsins are a group of lysosomal proteases (enzymes that degrades protein), found in all animals and other organisms, and perform a key role in cellular protein turnover. Cathepsin family includes serine proteases, aspartic proteases, and cysteine proteases. The aspartyl protease class is composed of cathepsins D and E. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. Cathepsin G includes serine protease class. Currently, there are no approved cathepsin inhibitors in the market, however various research and development activities are under process for the development of novel cathepsin inhibitors for treatment of various conditions such as cancer, traumatic brain injury, Ebola infection, and others.
Cathepsin Inhibitors Market Drivers
Various key players in the market are conducting clinical trials to gain approval for cathepsin inhibitors, which are under development phase and are expected to gain approval in the near future.
For instance, Merck Sharp & Dohme Corp.’s product, Odanacatib, also known as MK-0822, is under Phase 2 clinical trial. MK-0822 is a cathepsin K inhibitor under development for the treatment of postmenopausal women with osteoporosis. Hence, presence of novel products in the pipeline is expected to significantly support growth of the cathepsin inhibitors market during the forecast period.
Furthermore, high prevalence of diseases for which cathepsin inhibitors are being developed may rise demand for such novel treatment approaches in the near future. For instance, according to the data published by Centers of Disease Control and Prevention in 2017, traumatic brain injury (TBI) is a major cause of death and disability in the U.S. TBIs contribute to about 30% of all injury deaths. 153 people in the U.S. die per day, from injuries that include TBI.
Cathepsin Inhibitors Market Regional Analysis
North America cathepsin inhibitors market is expected to hold a dominant position in the global cathepsin inhibitors market, owing to the high prevalence of disease such as cancer, which will increase demand for novel cancer treatment approaches such as cathepsin inhibitors in region.
For instance, according to the data published by National Cancer Institute, it was estimated that in 2018, around 1,735,350 new cases of cancer will be diagnosed in the U.S. and around 609,640 people will die from the disease.
Europe cathepsin inhibitors market is also expected to show a significant growth during the forecast period, owing to frequent research and development activities by key players for the development of new cathepsin inhibitors in the region. For instance, F. Hoffmann-La Roche AG, a Switzerland-based pharmaceutical company, is developing RO5459072, a cathepsin S inhibitor, on the immune response to a gluten challenge in volunteers with celiac disease.
Cathepsin Inhibitors Market Key Players
Key players operating in global cathepsin inhibitors market include F. Hoffmann-La Roche AG, Merck Sharp & Dohme Corp., Virobay Inc., LEO Pharma, and others.
Cathepsin Inhibitors Market Taxonomy:
The global cathepsin inhibitors market is segmented on the basis of product type, indication, distribution channel, and region
By Product Type-
By Distribution Channel-
Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:
In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.
Coherent Market Insights desk research is based on a principle set of research techniques:
Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:
Preliminary Data Mining
The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.
Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.
Coherent Statistical model
We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:
Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.
This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:
The primary research is conducted with the ecosystem players including, but not limited to:
Finding it difficult to find the research that would cater to your business demands? Give us a chance to help you. One of our Research Consultants will connect to provide a customized solution.[email protected]
Talk to our research consultant to design an exclusive report as per your research needs.
We aim to fulfil client's research demands with tailored research solutions.
We aim to provide research studies in quickest turnaround time and in a much cost effective manner.
We cover each industry from supply and demand side with an aim to provide a most holistic research study.
We strive to provide most accurate and reliable research findings in our research reports.