Ephedrine is a decongestant and bronchodilator, used to treat bronchospasms caused due to asthma. The medicine reduces the swelling and constricts the blood vessels in the nasal passages which widens the lung airways and allows the patient to breathe easily. Due to the medicine’s central nervous system stimulatory effects, ephedrine is also used extensively during spinal anesthesia in order to prevent intra-operative hypotension. The medicine is available in the form of tablets, capsules and injections.

Global Ephedrine Market – Dynamics

High prevalence of hypotension during spinal anesthesia is expected to propel growth of the ephedrine market over the forecast period. For instance, according to the Columbian Journal of Anesthesiology, 2018, incidences of hypotension during spinal anesthesia ranges from 1.9% to 71% globally.  

Moreover, launches and approvals of ephedrine products is expected to boost the ephedrine market growth over the forecast period. For instance, in January 2017, Par Pharmaceutical, a subsidiary of Endo International plc, received approval from the U.S. Food and Drug Administration (FDA) for its new ephedrine sulfate injection, CORPHEDRA. The injection will be used to for the treatment of hypotension occurring in the process of spinal anesthesia.   

However, restrictions on ephedrine usage through regulatory authorities is expected to restrain the market over the forecast period. For instance, since 2001, the Government of Canada has authorized ephedrine only as a nasal decongestant with a maximum dosage of 8mg along with 32mg in a 24 hour period.

Global Ephedrine Market – Regional Insights

North America accounted for the largest market share in 2018, owing to launches and approvals of new ephedrine products in the region. For instance, in March 2017, Akorn, Inc., a developer and manufacturer of generics and branded prescription pharmaceuticals, received the U.S. Food and Drug Administration (FDA) approval for its New Drug Application (NDA) for single dose ampule of an ephedrine sulfate injection which is indicated for treating hypotension occurring during spinal anesthesia.

Increasing ephedrine product launches is expected to propel the market growth in the Europe region. For instance, in April 2016, Avadel Pharmaceuticals, formerly known as Flamel Technologies, received approval from the U.S. Food and Drug Administration for Akovaz, an ephedrine sulfate injection, which will be used to treat hypotension occurring during anesthesia. 

Moreover, high prevalence of hypotension during spinal anesthesia in Asia Pacific is likely to drive the ephedrine market over the forecast period. For instance, according to a study published in the Indian Journal of Anesthesia, 2018, the cases of mild, moderate, and severe spinal anesthesia induced hypotension was approximately 20%, 35%, and 40% respectively.  

Global Ephedrine Market – Competitive Landscape

Key player operating in the market include Servier, Merck Sharp & Dohme Corp., Amgen Inc., Sanofi S.A., Avadel Pharmaceuticals, GlaxoSmithKline plc, Endo Pharmaceuticals plc, and Akorn Inc.

Global Ephedrine Market – Taxonomy

On the basis of dosage form, the global ephedrine market is segmented into:

  • Tablets
  • Capsules
  • Injections

On the basis of disease indication, the global ephedrine hormones market is segmented into:

  • Bronchial Asthma
  • Spinal Anesthesia induced Hypotension
  • Others

On the basis of distribution channel, the global ephedrine hormones market is segmented into:

  • Hospitals Pharmacies
  • Retail Pharmacies
  • Others

On the basis of region, the global ephedrine hormones market is segmented into:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
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In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Data Triangulation Methodology | Coherent Market Insights

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Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

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Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

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Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

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The primary research is conducted with the ecosystem players including, but not limited to:

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