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Iloprost is a drug used for treating diseases such as pulmonary arterial hypertension, scleroderma, Raynaud syndrome, and other conditions where constriction in blood vessels and improper blood flow in tissues is found. The trade name of the drug is Ventavis or Ilomedine. Iloprost, which received approval by the U.S. Food and Drug Administration (FDA) in 2004 for pulmonary arterial hypertension.

Iloprost dilates the narrowed blood vessels (arteries) in lungs which results in decreased pulmonary blood pressure to the heart. The drug can be administered either through infusion or it can be inhaled using nebulizers. The infusion is administered intravenously which lasts for about six hours in a day and the session is repeated for three to five days in a row whereas the inhalations should be done six to nine times in a day, according to the physician’s prescription.

Global Iloprost Drugs Market – Dynamics

Increasing prevalence of pulmonary arterial hypertension is expected to propel the market growth over the forecast period. For instance, according to the National Organization for Rare Disorder (NORD), 2018, nearly 500 to 1000 new cases of pulmonary arterial hypertension are diagnosed each year in the U.S.

Moreover, various merges, agreements and acquisitions of major companies are likely to propel the market growth. For instance, in January 2017, Acetlion announced that Johnson & Johnson will be acquiring the firm including its marketed products in pulmonary arterial hypertension franchise.

Furthermore, increasing number of players are focusing on developing this drug, in order to, which is also contributing to the market growth over the forecast period. For instance, in 2018, according to the National Institute of Health, approximately15 clinical trials involving Iloprost were active globally. For instance, in November 2015, the National Cancer Institute initiated a phase I clinical trial for evaluating iloprost in preventing recurrence of lung cancer for patients who smoke and the study is expected to complete in 2020.

However, the drug has some side effects such as kidney failure, dyspnea, chest pain, short breath, and swelling of limbs. The above stated side effects are expected to restrain the market growth over the forecast period.

Global Iloprost Drugs Market – Regional insights

North America accounted for the largest market share in 2018, owing to mergers, agreements, and acquisitions by key players in the region. For instance, in August 2019, VisionGate, a U.S. -based oncology pharmaceutical and diagnostics company, received an exclusive worldwide right and license from Bayer AG for the technology to develop, manufacture, sale, and commercialize iloprost betadex clathrate in the field of lung cancer treatment and prevention. Also, in 2012, Bayer AG collaborated with Vectura to develop Breelib, which is a hand held nebulizer device designed for improved delivery of Bayer’s Ventavis (iloprost).

Global Iloprost Drugs Market - Competitive Landscape

Key manufactures in the market include Actelion Pharmaceuticals, Bayer AG, Vectura Group Plc., and VisionGate. Moreover, key players in market are focused on developing new products, in order to enhance their market share. For instance, in 2017, Bayer AG and Vectura Group Plc. extended their collaboration again to develop an upgraded version of nebulizer Breelib which improves the efficacy of iloprost aerosol therapy in pulmonary atrial hypertension. According to the National Institute of Health, the nebulizer is still in clinical trial and the study is expected to finish in March 2020.

Global Iloprost Drugs Market – Taxonomy

On the basis of route of administration, the global iloprost drugs market is segmented into:

  • Intravenous
  • Inhalation

On the basis of distribution channel, the global iloprost drugs market is segmented into:

  • Hospitals Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

On the basis of region, the global iloprost drugs market is segmented into:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa
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Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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