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Adjuvant is an integral part of a vaccine that helps to develop strong immune response in the human body. Conventional vaccines are derived from toxin, inactivated whole organism, and live-attenuated, which are effective in stimulating antibody-based immunity. Adjuvants are used to enhance efficiency of vaccines as conventional vaccines are highly reactogenic in nature. Various molecules have been considered for use as an adjuvant, such as mineral salts, oil emulsions, microbial derivatives, particulate adjuvants, and plant derivatives. Based on the mechanism of action, the adjuvants are categorized into two types, which include particulate vaccine delivery systems that specifically target antigen to antigen presenting cells (APCs) and the immunostimulatory adjuvants that interacts with toll like receptors (TLRs) of the cell resulting in inflammatory response that amplify the innate immune response.

Immunostimulatory Adjuvants Market – Dynamics

Increasing government initiatives to prevent epidemic due to various chronic diseases and increasing national immunization programs around the globe to promote health awareness regarding vaccination among the population has boosted the growth of the immunostimulatory adjuvants market size. For instance, the Global Vaccination Action Plan (GVAP) was endorsed by the heath ministers of 194 member’s states of the world health assembly in 2012. The aim of the Global Vaccination Action plan was to introduce new improved vaccines, advance research work for next generation vaccines, and to strengthen routine immunization. GVAP urges countries to strengthen governance of national immunization programs and to keep up-to-date monitoring of data. Moreover, private organizations intervention at the global scale for the better vaccines research and development has propelled the market growth. For instance, The Bill and Melinda Gates Foundation in 2010, pledged US$ 10 billion to support the vaccine research and the development and delivery of vaccines to the underdeveloped countries. Furthermore, increasing prevalence of the chronic disease such as rubella and measles around the globe has significantly bolstered the immunostimulatory adjuvants market growth. For instance, according to the Centers for Disease Control and Prevention (CDC) facts more than 100,000 children born every year with congenital rubella syndrome mainly in the Western Pacific region, South East Asia, and Africa region. Furthermore, the World Health Organization (WHO) estimated around 145,700 deaths globally from measles in 2013. These incidences have led government and national organization to invest more into adjuvant vaccines market significantly. However, strict regulatory requirements and huge investment required for developing a new adjuvant are expected to hinder the growth of global immunostimulatory market.

Immunostimulatory Adjuvants Market – Regional Insights

Based on the region, the global immunostimulatory market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America immunostimulatory adjuvants market holds the dominant position in terms of revenue. Moreover, Presence of major market players in U.S. region and increasing federal support towards the growth of healthcare sector is propelling growth of the immunostimulatory adjuvant market. For instance, the Center for Diseases Control and Prevention (CDC) was allocated US$ 324,350,000 in the 2016, for the public health immunization and to increase vaccine coverage among adults, adolescents, and children. Asia Pacific is expected to gain significant market share in the global immunostimulatory adjuvants market, followed by Europe, owing to high prevalence of various chronic disease such as tuberculosis, measles, and rubella. For instance, according to the World Health Organization (WHO) around 2.79 million incidence cases of tuberculosis were registered in India in 2016.

Immunostimulatory Adjuvants Market – Competitive Landscape

Key players operating in the global immunostimulatory adjuvant market include Bayer, Adjuvance Technologies, Vical, Allergy Therapeutics, BioCenturay, and Recenttec. Market players are focused on adopting strategies such as new product launch, collaborations, and mergers to provide innovative products to maintain leading position in the market. For instance, in 2017, Bayer collaborated with Bitkom, to provide digital innovation in the areas of health care.

Immunostimulatory Adjuvants Market – Taxonomy

On the basis of type, the global immunostimulatory adjuvants market is segmented into:

  • Freund Adjuvant
  • Aluminum Hydroxide Adjuvant
  • Alum Adjuvant
  • Liposomes
  • Other

On the basis of distribution channel, the global immunostimulatory adjuvants market is segmented into:

  • Hospitals
  • Medical Centers
  • Other

On the basis of geography, the global immunostimulatory adjuvants market is segmented into:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users