Contact Us
Phase-Xs | Biologics & Biosimilars | Coherent Market Insights

Liver cancer is a type of malignant hepatic tumor in or on the liver, which may cause due to excessive alcohol intake, diabetes, certain inherited liver diseases, and hepatitis. Symptoms of this cancer appears only when it is in the advanced stage. The most common type of liver cancer is hepatocellular carcinoma, which begins in the main type of liver cell. Other types of liver cancer such as hepatoblastoma and intrahepatic cholangiocarcinoma are less common. Incidence rate of liver cancer is high in the U.S., owing to prevalence of cirrhosis caused by nonalcoholic fatty liver disease and chronic hepatitis C.  According to American Cancer Society 2017, Liver cancer is the 10th most common cancer and fifth most common cause of death among men in the U.S. Also, it is the eighth most common cause of death among women. Colorectal cancer is expected to be one of the precursor for liver cancer. According to International Scholarly Research Network, a clinical study on Percutaneous Cryoablation of Metastatic Lesions from Colorectal Cancer in 2012: Efficacy and Feasibility with Survival and Cost-Effectiveness Observations, around 50% of the patient suffering from colorectal cancer develop liver cancer.

Liver cancer therapeutics Market – Driver

Increasing research to identify the causes of liver cancer is expected to boost growth of the liver cancer therapeutics market during the forecast period. For instance, in November, 2014, researchers at the San Diego School of Medicine and University of California found that long-term exposure to triclosan, a common ingredient in detergents and soaps, causes liver fibrosis and cancer in laboratory mice. However, triclosan has not been proven to cause liver cancer in human and it is currently under scrutiny by the Food and Drug Administration (FDA) to determine whether it has negative health impacts.

Moreover, increasing prevalence of liver cancer in various regions is expected to drive growth of the market. For instance, according to cancer research organization of UK, around 5,736 new cases of liver cancer were reported in UK in 2015. Furthermore, according to cancer organization, around 40,710 new cases of liver cancer was diagnosed in the U.S. during 2017, three of which will be hepatocellular carcinoma (HCC).

Organic and inorganic strategies by market players such as merger, collaboration, acquisition, and research and development for developing new therapies for liver cancer is expected to boost growth of the market. For instance, in 2013, Roche and Inovio Pharmaceuticals, Inc. entered into license agreement to research, develop and commercialize Inovio’s highly-optimized, multi-antigen DNA immunotherapies targeting hepatitis B and prostate cancer. It has also been shown that liver cancer risk increases substantially with the increase in Body Mass Index (BMI) of an individual. More than half of the adult population in the U.S. is overweight, which is propelling demand for therapeutic drugs of liver cancer, which in turn is creating opportunities for manufacturers.

Liver cancer therapeutics Market – Restrain

Stringent regulatory approvals to ensure the safety of drugs and cost of these drugs may hamper the growth of the liver cancer therapeutics market during the forecast period. For instance, in March 2017, ArQule, Inc’s product- tivantinib did not clear phase 3 clinical trial for hepatocellular carcinoma (HCC) in japan, as it did not meet its primary endpoint of progression free survival (PFS)

Liver cancer therapeutics Market - Regional Analysis

Geographically, global liver cancer therapeutics market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold dominant position over the forecast period, owing to increasing funding for research and development activities by government. American Liver Foundation is an organization that promote education, support and research for the prevention, treatment, and cure of liver disease and since 1979, this organization has provided more than US$ 26 million in research funding. Furthermore, liver cancer is more common in economies of Sub-Saharan Africa and Southeast Asia as compared to the U.S. According to GLOBOCAN, in 2012, around 83% (50% in China alone) of the estimated 782,000 new cancer cases were reported worldwide. Moreover, in Sub Saharan African countries, the risk of developing cancer and death from the same is high, owing to the late stage diagnosis and lack of treatment, which is driving growth of the liver cancer therapeutics market.

Liver cancer therapeutics Market – Competitor

The market players operating in liver cancer therapeutics market include Bayer AG, Bristol-Myers Squibb Company, Onyx Pharmaceuticals, Inc., Alnylam Pharmaceuticals, Inc., Pfizer Inc., F. Hoffmann-La Roche Ltd., Jennerex Biotherapeutics Inc., and Celsion Corp.

Liver cancer therapeutics Market – Taxonomy

By Drug Class

  • Targeted Therapy
    • Sorafenib (Nexavar)
    • Regorafenib (Stivarga)
  • Immunotherapy
    • Nivolumab (Opdivo)
  • Chemotherapy

By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

Subscribe Newsletter

Kindly Subscribe for our latest news & articles.