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Phase-Xs | Biologics & Biosimilars | Coherent Market Insights

Meningitis is an inflammation in the inner lining of the brain and spinal cord that results from infectious (viral, bacterial, and rarely fungal) or non-infectious (drugs, sarcoidosis etc.) factors. The swelling associated with meninges triggers symptoms such as painful headaches, fever, loss of appetite, and stiffness of the neck. Meningitis is a fatal disease and has a rapid onset of action. Meningitis can cause severe damage to the brain in almost half of the total infected population, if untreated. It can also lead to serious ailments such as mental retardation, epilepsy, and deafness. According to Meningitis Research Foundation, as of 2017, around 80% - 90% of meningitis cases are estimated to be caused by enteroviruses and the remaining 10% is estimated to be caused by herpes virus, mumps, measles, and human immune deficiency virus. The major causes of bacterial meningitis are Neisseria meningitis (causing meningococcal disease), Haemophilus influenzae type b (causing Hib disease), and Streptococcus pneumonia (causing pneumococcal disease). Prolonged exposure to these bacteria can spread the infection. In 2010, According to the Confederation of Meningitis Organizations Inc., around 50% of the bacterial meningitis cases occur in children under the age of five years and in adolescent and young adults from 15-24 year of age.

Meningitis Treatment Market Taxonomy

By Causative Micro-organism

  • Bacterial
  • Viral
  • Fungal

By Treatment Type

  • Antibiotic Therapy
  • Adjunctive Therapy

By Vaccine Type

  • Meningococcal Conjugate Vaccine
  • Meningococcal Polysaccharide Vaccine (MPSV4)
  • Combination Vaccine

Innovation in technology to combat infectious diseases is expected to drive the future meningitis treatment market

Major driving factor for growth of the meningitis treatment market include the alliance of public and private sectors to increase availability of vaccine to the populace. For instance, Global Alliance for Vaccines and Immunization (GAVIs), an international organization, brings together public and private sectors with a goal to provide access to all the latest vaccines to children in the world’s poorest countries. People suffering from immune compromised diseases such as HIV, cancer, diabetes, and organ transplants are at higher risk of contracting aseptic meningitis. Additionally, advancements in diagnostics and technological platforms are attributed to augmentation of the meningitis treatment market. For instance, in 2009, venture by Cadila with a U.S.-based vaccine company – Novavax, aimed to develop and manufacture therapeutic and prophylactic vaccines to combat infectious diseases. Introduction of new vaccine with improved mechanism, and growing advancement in genetics and immunology are expected to boost growth of the meningitis treatment market. Additionally, factors such as high incidence rate with major brain injuries via road accidents are propelling growth of the market for meningitis treatment worldwide. On the contrary, stringent regulations and alternate medications are factors hindering growth of the meningitis treatment market.

On the basis of geography, the global meningitis treatment market is expected to be the most prominent in the sub-Saharan belt of African, which is also known as the meningitis belt due to higher incidence rate of meningitis C. The second highest incidence rate is recorded in India as reported by the World Health Organization (WHO), 2015. Around 12,000 cases of meningitis C and 800 deaths were recorded in Nigeria, in 2015. This indicates the rising incidence rate of meningitis, which in turn, is expected to propel growth of the meningitis treatment market in the near future.

Global Meningitis treatment market is expected to gain momentum due to high cases of acute meningitis

The key players operating in the meningitis treatment market include Biomed Pvt. Ltd, Novartis, Nuron Biotech, Pfizer, Baxter, Merck & Co., GSK, and Sanofi. The market is set to gain momentum due to current unmet needs of vaccinations and increasing incidence of meningitis globally. Joint ventures, collaborations, and investment in research and development activities by various companies are expected to boost growth of the market. For instance, to treat aseptic meningitis, Bristol-Myers Squib is focusing on development of biologics – nivolumab (Opdivo) is in phase 3, and ipilimumab in phase 2.


Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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