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Optogenetics is an emerging medical technique, which involves the use of light to control cells in living tissues, especially neurons to help study the characteristics of normal and abnormal brain function. Optogenetics is an emerging field of biotechnology trending among the fields of neuroscience, cardiology, ophthalmology, behavioral science, and other healthcare domains. The technique is widely used to treat neurological disorders such as depression. Depression is caused by chronic stress that causes a series of negative memories. Optogenetics technology is used by placing the genes that express light-sensitive proteins into mammalian cells, which normally lack such proteins. When the proteins are illuminated with specific wavelengths of light, they change the behavior of the cells, thereby introducing certain types of ions or pushing out a few to alter electrical activity. Furthermore, optogenetics has also been used in the treatment of retinal disease and hearing impairment. Advancements in optogenetics technology has led to a sound understanding of neuroscience. Presently, multiphoton excitation microscopy is the technique that is used for investigating optogenetic studies of live animal brain at single neuron resolution.

Wireless microchips emerging as a new technology in optogenetics is expected to boost market growth

The major factor contributing to growth of the global optogenetics market is the rising use of optogenetics in the field of neuroscience. New developments in optogenetics such as wireless microchips have enabled convenient treatment of conditions, including depression and Parkinson’s disease. According to World Health Organization (WHO) in 2017, it is estimated around 300 million people were affected by depression globally which makes it the main cause of disability such as decrease in self-esteem, feeling bored and loss of a direction or purpose  . Furthermore, rampant advancements in technology such as ultrafast laser tools, LEDs, ytterbium-based lasers are the other factors responsible in driving the growth of optogenetics market. However, reluctance in adoption of new technology by healthcare professionals due to high costs in the deployment of technology, lack of awareness regarding the tools in emerging economies, and lack of availability of genetic reagents that can be conveniently used for probing biological processes are factors hindering growth of the optogenetics market.

Optogenetics Market Taxonomy

Optogenetics market is segmented into sensors, techniques, application, light equipment, and geography.

On the basis of sensors, the global optogenetics market is segmented into

  • Genetically Modified Calcium Indicators
  • pH Sensors
  • Neurotransmitter Release
  • Voltage-sensitive Fluorescent Proteins

On the basis of techniques, the global optogenetics market is segmented into

  • Channelrhodopsin
  • Halorhodopsin
  • Archaerhodopsin

On the basis of application, the global optogenetics market is segmented into

  • Retinal Disease Treatment
  • Cardiovascular Ailments
  • Neuroscience
  • Behavioral Tracking and Pacing

On the basis of light equipment, the global optogenetics is segmented into

  • Lasers
  • LEDs
  • Others

On the basis of region, optogenetics market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold the dominant position in the optogenetics market, owing to the rising demand for light therapy treatment for chronic pain in the region. For instance, According to Montreal Neurological Institute, the light treatment therapy has the ability to control virtually any type of neuron in the brain with pulses of light, thus making it precise both, in terms of timing and type of cells affected. Thus, optogenetics has proved to have a much more targeted approach to chronic pain relief than the conventional methods, which cannot be localized with the same precision as a beam of light. Furthermore, Asia Pacific is expected to hold a major market share in the global optogenetics market during the forecast period, primarily attributed to increasing adoption of optogenetic techniques and ultrafast laser tools by several neuroscience labs.

Growing application areas for optogenetics is expected to propel market growth

Key players in the optogenetics market include Coherent, Inc., Thorlabs, Inc. Cobalt, Inc., Scientifica, Laserglow Technologies, Regenxbio, Inc., Gensight, Addgene, UPenn Vector Core, and Jackson Laboratories. The key players are focusing on strategic mergers and acquisitions and development of innovative systems. For instance, Coherent Inc. launched a new type of short pulse ultrafast laser sources that provides wide wavelength (680-1300nm) tunability of the primary output as well as simultaneous high power (1.5 watts) output at 1040 nm. Furthermore, this combination makes lasers such as Chameleon Discovery ideal for demanding multiphoton excitation application in optogenetics.


Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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