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Phase-Xs | Biologics & Biosimilars | Coherent Market Insights

Cardiovascular diseases remain a leading cause of mortality and morbidity worldwide. The development of peptide as therapeutic agent has been avoided by pharmaceutical industry due to its low stability, size, degradation rate, and poor stability. However, recently, resurgence has taken place in developing peptides in therapeutic action. Peptides are short chains of amino acid monomers linked by peptide bond. Peptides are distinguished from proteins on the basis of size. Increasing prevalence of cardiovascular diseases such as cardiac arrest and chest pain and increasing research and development in peptide-based drug therapies is expected to drive the market growth.

Peptide-based Cardiovascular Therapeutics Market-Drivers

Increasing prevalence of cardiovascular diseases globally is expected to drive the peptide-based cardiovascular therapeutics market growth during the forecast period. For instance, according to the World Health Organization 2017 report, around 17.9 million deaths were recorded from cardiovascular diseases worldwide in 2016.

Furthermore, research and development and clinical trials of new peptide-based therapeutics is expected to drive growth of the peptide-based cardiovascular therapeutics market during the forecast period. For instance, according to the National Center for Biotechnology Information’s 2015 report, there is an increasing interest in peptide formation in pharmaceutical research and development (R&D) and around 140 peptide-based therapeutics are being evaluated in clinical trials.

Peptide-based Cardiovascular Therapeutics Market-Restraints

Rapid metabolism of peptide drug is expected to restrain the peptide-based cardiovascular therapeutics market growth during the forecast period. For instance, according to National Center for Biotechnology Information’s 2015 report, natural peptides have poor absorption, distribution, metabolism, and excretion (ADME) properties with rapid clearance, short half-life, low permeability, and low solubility.

Peptide-based Cardiovascular Therapeutics Market-Regional Analysis

On the basis of region, the peptide-based cardiovascular therapeutics market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold dominant position in the peptide-based cardiovascular therapeutics market over the forecast period, owing to increasing number of approvals for therapeutic peptides. For instance, according to the Drug Discovery Today Journal, in 2015, over 60 therapeutics peptides were approved by the U.S. Food and Drug Administration (FDA) in the U.S.

Asia Pacific is the fastest growing market for peptide-based cardiovascular therapeutics, due to increasing prevalence of cardiovascular diseases in the region. For instance, according to China’s National Center for Cardiovascular Diseases’ report in 2017, the total number of patient suffering from cardiovascular diseases in China was 290 million.

Peptide-based Cardiovascular Therapeutics Market-Competitive Landscape

Key players operating in the peptide-based cardiovascular therapeutics market include, Pfizer Inc., Apotex Holdings, Inc., Fresenius Kabi USA, AstraZeneca, Corden Pharma GmbH, Merck & Co., Inc., Novetide Ltd., and Dr. Reddy’s Laboratories Limited.

Peptide-based Cardiovascular Therapeutics Market-Taxonomy

The peptide-based cardiovascular therapeutics market is segmented on the basis of drug type, distribution channel, and region.

By Drug Type:

  • Bivalirudin
  • Eptifibatide

 By Distribution Channel:

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy

By Region:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users