Contact Us
Phase-Xs | Biologics & Biosimilars | Coherent Market Insights

Photopheresis is a form of apheresis and photodynamic therapy in which blood is treated with photosensitizing agents and irradiated with specific wavelengths of light. It is also known as extracorporeal photopheresis (ECP). ECP is leukapheresis based therapeutic procedure approved by the U.S. Food and Drug Administration for treatment of advance cutaneous T-cell lymphoma. Additionally, ECP is used in treating disorders like graft versus host disease (GVHD), atopic dermatitis, scleroderma, lichen planus, lupus erythematosus, Crohn’s disease, type 1 diabetes. Many photopheresis products like open and closed systems are available in the market, of which, only closed system is approved by the U.S. FDA, because of its lower risk of contamination and infection during reinfusion. Furthermore, closed systems are technologically advanced systems in comparison to open systems.

Photopheresis Products Market Drivers

Rise in prevalence of autoimmune diseases and increase in number of organ transplant cases is expected to lead to growth of the photopheresis products market. Increasing reimbursement policies by governments also expect to boost the photopheresis product market. For instance, in August 2016, Mallinckrodt Pharmaceuticals, a leading specialty pharmaceutical company, announced that Switzerland’s Federal Department of Home Affairs (FDHA) approved the reimbursement of ECP treatment for patients in Switzerland.

Furthermore, business strategies such as collaborations by key players in the photopheresis field, helps to improve the understanding of photopheresis’ effect on immune modulations across several severe and critical conditions. For instance, on February 2019, Mallinckrodt plc. announced the research collaboration agreement with Transimmune AG, a company developing novel immunotherapies, for the development of the activation of antigen presenting cells. Both companies intend to explore the next generation Mallinckodt photopheresis system.

However, lack of photopheresis treatment centers, high cost and product recalls involved in the therapy may restrain the growth of photopheresis products market. For instance, according to report published by American Society of Hematology in 2017, the number of chronic graft versus host disease (cGVHD) patients increased from 16 in 2009 to 100 in 2016 and ECP use increased from 31.3% in 2009 to 54% in 2016 in the U.S. The total annual cost per patient was US$ 190,148 including US$ 4619 for emergency room visits, and US$ 176,856 for hospitalization during follow up period.

Moreover, on April 5, 2016, photopheresis product, THERAKOS CELLEX, was recalled by the manufacturer Mallinckrodt (Therakos) because the post-marketing monitoring process detected an increasing trend in tubing leaks within the pump tubing organizer.

Photopheresis Products Market - Regional Insights

On the basis of region, the global photopheresis products market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America holds a dominant position in the global photopheresis products market as its government provides the reimbursements for various treatments like GVHD, cytotoxic T-lymphocytes and lung transplantation treated by ECP therapy are the factors accountable for growth of the market. According to Leukemia and Lymphoma society, in 2017, 30-70% people suffer from cGVHD. Moreover, frequent approvals by regulatory bodies by European commission for photophoresis products are expected to drive the market. For instance, in August 2016, Swiss regulators approved the reimbursement of Mallinckrodt plc.’s ECP treatment for patients suffering from bronchiolitis obliterans syndrome (BOS), following a lung transplant.

Photopheresis Products Market - Competitive Landscape

Some of the key players operating in the global photopheresis products market include Macopharma, Fresenuis Kabi AG, Haemonetics Corporation, Terumo Corporation, Dover Medical, Med Tech Solutions GmbH, and Mallinckrodt Pharmaceuticals.

Photopheresis Products Market - Market Taxonomy

On the basis of product type, the global photopheresis products market is segmented into:

  • Open System
  • Closed System

On the basis of application, the global photopheresis products market is segmented into:

  • Graft versus Host Disease
  • Cutaneous T-Cell Lymphoma
  • Transplant Rejections
  • Autoimmune Diseases

On the basis of end user, the global photopheresis products market is segmented into:

  • Hospitals
  • Specialty Clinics
  • Ambulatory Surgical Centers

On the basis of region, the global photopheresis products market is segmented into:

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Middle East
  • Africa

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.

Data Triangulation Methodology | Coherent Market Insights

Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

Market Analysis | Coherent Market Insights

Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

Subscribe Newsletter

Kindly Subscribe for our latest news & articles.