The Global Anti-Obesity Drug Market is estimated to be valued at USD 25.87 Bn in 2025 and is expected to reach USD 82.55 Bn by 2032, exhibiting a compound annual growth rate (CAGR) of 18.01% from 2025 to 2032. This significant growth reflects the increasing global prevalence of obesity and rising demand for effective pharmaceutical interventions. Innovations in drug formulations and expanding healthcare infrastructure in emerging markets also contribute to the robust market expansion over the forecast period.
Market trends indicate a strong shift towards personalized medicine and combination therapies in the anti-obesity drug sector, driven by a better understanding of obesity’s multifactorial nature. Additionally, increasing investments in research and development are fueling the introduction of novel drugs with improved efficacy and safety profiles. Digital health integration, such as mobile health apps for monitoring and adherence, is further enhancing patient outcomes, while growing awareness about obesity-related health risks is driving demand across both developed and developing regions.
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Emergence of Digital Therapeutics
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Australia Considers Subsidizing Weight-Loss Drugs |
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In terms of drug type, the prescription drugs segment is expected to contribute the highest share of the global anti-obesity drug market with a share of 65.1% in 2025 owing to multiple critical factors that underscore their widespread adoption and acceptance. Primarily, prescription drugs benefit from rigorous clinical validation, ensuring higher efficacy and safety profiles than Over-the-Counter (OTC) alternatives. This guarantees greater confidence among healthcare professionals when recommending these treatments to patients. The increasing prevalence of obesity-related comorbidities such as diabetes, cardiovascular diseases, and hypertension has escalated the demand for more potent and targeted therapies, roles best fulfilled by prescription drugs.
According to a study by BMC Public Health, in January 2025, the escalating prevalence of obesity-related comorbidities, particularly type 2 diabetes, is a growing global health concern. Research indicates that obesity is linked to 30–53% of new diabetes cases annually in the U.S. Similarly, in India, obesity is a significant risk factor for diabetes, with approximately 26% of the global diabetic population residing in the country.
Clinical advancements in prescription formulations have notably enhanced patient adherence and outcomes, with many drugs offering multifaceted mechanisms that precisely target metabolic pathways responsible for weight gain. Government and private health insurance support often cover these prescription medications, making them more accessible to a broader demographic, especially in countries with well-established healthcare infrastructure. Conversely, OTC drugs are frequently limited by their milder efficacy and regulatory constraints, which restrict their use for more severe or complex obesity cases.
Within the global anti-obesity drug market segmented by drug class, GLP-1 (Glucagon-Like Peptide-1) Receptor Agonists hold the highest share with an estimated 22.1% in 2025, driven largely by their dual role in appetite regulation and glucose metabolism. These agents mimic the incretin hormones, which enhance insulin secretion and suppress glucagon release, leading to potent effects on weight reduction and glycemic control. This makes GLP-1 receptor agonists particularly attractive for patients with obesity complicated by type 2 diabetes, establishing them as a cornerstone treatment option.
The significant success of key drugs like Semaglutide, Liraglutide, and Tirzepatide illustrates the segment’s appeal. These therapies not only contribute to substantial and sustained weight loss but also improve cardiovascular health markers, which is crucial for obese individuals facing elevated risks of heart disease. Their multifaceted benefits extend beyond mere weight management, encompassing improved metabolic profiles that reduce long-term health risks.
In April 2025, according to an article published by the Heart Rhythm Society, a recent clinical study, TRANSFORM-AF, found that GLP-1 receptor agonists (GLP-1 RAs), typically used for diabetes, may reduce atrial fibrillation (AF)-related events in patients with both obesity and AF. Conducted across 170 Veterans Affairs hospitals, the study showed a 13% reduction in major AF-related events, including hospitalizations and ablation procedures, with the greatest benefits seen in patients with severe obesity.
By route of administration, the oral segment is expected to command the highest share in the global anti-obesity drug market with 32.1% in 2025, predominantly because of patient preference and its convenience in daily use. Oral medications provide a non-invasive, easily self-administered option that significantly improves adherence, particularly for long-term weight management where continuous treatment is often necessary.
Patients generally favor oral anti-obesity drugs as they reduce the discomfort and complexity associated with injectables or transdermal patches, allowing for discreet and flexible dosing. The global rise in telehealth consultations and online pharmacies further boosts accessibility to oral formulations, overcoming geographical and logistical barriers. In addition, many oral drugs exhibit favorable stability and shelf life, ensuring easier storage and transportation across diverse markets.

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North America’s dominance in the global anti-obesity drug market with an estimated share of 38.3% in 2025 stems from a well-established healthcare infrastructure, strong pharmaceutical industry presence, and comprehensive government policies supporting obesity management. The region benefits from high healthcare expenditure and widespread awareness about obesity-related health risks. The presence of major pharmaceutical companies such as Novo Nordisk, Pfizer, and Eli Lilly drives innovation and extensive clinical trials, ensuring a robust pipeline of anti-obesity therapies. Additionally, favorable regulatory frameworks by agencies like the USFDA facilitate faster drug approvals.
For instance, on November 8, 2023, the U.S. Food and Drug Administration (FDA) approved Zepbound (tirzepatide) for chronic weight management in adults with obesity (BMI ≥30 kg/m²) or overweight (BMI ≥27 kg/m²) with at least one weight-related condition, such as high blood pressure or type 2 diabetes. Zepbound, developed by Eli Lilly and Co., is already approved as Mounjaro for improving blood sugar in adults with type 2 diabetes. The approval addresses the growing need for treatments in the face of increasing obesity rates in the U.S.
The Asia Pacific region is expected to exhibit the fastest growth owing to rising obesity prevalence driven by urbanization, lifestyle changes, and increasing disposable incomes with a share of 24.2% in 2025. Governments across countries like China, India, Japan, and South Korea are implementing awareness campaigns and supporting healthcare reforms to tackle obesity, creating a conducive environment for market expansion. The growing middle-class population demanding better healthcare options fuels demand. Additionally, the presence of emerging pharmaceutical companies and increased foreign direct investments contributes to market dynamism. Trade liberalization and improved healthcare infrastructure, coupled with collaborations between multinational and local companies, further accelerate growth in this region.
For instance, on June 03, 2025, Biocon Limited, a global biopharmaceutical company known for affordable biologics and generics, received approval in India for its diabetes treatment Liraglutide. Its subsidiary, Biocon Pharma, also secured approval for the 6 mg/ml injectable formulation in pre-filled pens and cartridges. This generic version of Victoza is indicated for Type 2 diabetes in adults and children over 10, alongside diet and exercise. Liraglutide is a synthetic GLP-1 analog given as a once-daily injection. First approved in the EU in 2009 and the US in 2010 for diabetes, it later received U.S. FDA approval in 2014 and EMA approval in 2015 for weight management in obese or overweight adults with related conditions.
The U.S. remains the most crucial market within North America, supported by significant investments in research and development and a proactive regulatory regime. Industry giants like Pfizer, Novo Nordisk, and Eli Lilly dominate, offering a broad portfolio that includes GLP-1 receptor agonists and other advanced therapeutics. The country’s high obesity rates, combined with increased health awareness and reimbursement schemes, have significantly contributed to the growing adoption of obesity treatments.
For instance, in September 2024, new research from the U.S. Centers for Disease Control and Prevention (CDC) reveals that nearly 1 in 10 adults in the U.S. report severe obesity, with women being nearly twice as likely as men to be affected. While the overall obesity rate remains high at about 40%, the proportion of those with severe obesity has increased over the past decade. Severe obesity is strongly linked to higher risks of cardiovascular disease and diabetes.
China's rapid urbanization and changing diets have fueled a growing obesity crisis, with projections showing that by 2030, 70.5% of adults and 31.8% of children may be obese. In response, the government is focusing on health reforms and chronic disease management, driving the demand for anti-obesity medications. Companies like Novo Nordisk are forming joint ventures with local firms to cater to Chinese patients. Experts also propose creating integrated chronic disease clinics to combine weight management with treatments for conditions like diabetes and heart disease, offering a more holistic approach to healthcare. This positions China as a key market for obesity treatments in the coming years.
For instance, in May 2025, according to the National Library of Medicine, China is facing a growing obesity crisis, with predictions showing that by 2030, 70.5% of adults and 31.8% of children may be obese. To address this, experts propose creating integrated chronic non-communicable disease (NCD) management clinics that combine weight management with the treatment of obesity-related conditions like diabetes and heart disease. These clinics, using multidisciplinary teams, would offer personalized care, improve outcomes, and optimize healthcare resources, providing a more holistic approach to China’s rising health challenges.
Germany’s anti-obesity drug market benefits from a robust healthcare infrastructure, extensive insurance coverage, and strong regulatory support for innovative therapies. Pharmaceutical companies including Bayer and Pfizer play prominent roles by offering a variety of prescription anti-obesity drugs. The country’s focus on lifestyle-related disease management, coupled with government campaigns promoting healthier living, aids market penetration.
For instance, in April 2025, according to data published by Lancet under the journal of public health in Germany, Germany's public health system faces challenges despite high spending, with rising rates of lifestyle-related diseases like obesity, smoking, and heart disease. In response, the government has increasingly focused on managing these diseases through campaigns promoting healthier living. For instance, recent initiatives have aimed to reduce alcohol consumption and encourage healthier eating habits, particularly among youth. The government is urged to strengthen coordination, increase funding for prevention programs, and develop a comprehensive national public health strategy to tackle these growing health issues.
The India Anti-Obesity Drug Market is estimated to be valued at USD 1.24 Bn in 2025 and is expected to reach USD 4.38 Bn by 2032, exhibiting a compound annual growth rate (CAGR) of 19.7% from 2025 to 2032.
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Category |
Details |
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Generic Name |
Orlistat, Liraglutide, Semaglutide, Tirzepatide |
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Brand Names (India) |
Xenical, Saxenda, Wegovy, Mounjaro |
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Therapeutic Class |
Anti-Obesity |
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Approved Indications |
Treatment of Obesity, Type-2 Diabetes, Weight Management |
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Dosage Forms (Approved) |
Orlistat 60mg (OTC) / 120mg (Rx) capsules Liraglutide 3.0 mg/mL pre-filled injection pen Semaglutide 2.4 mg weekly pre-filled injection pen |
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Key Manufacturers |
Sun Pharma (Orlistat), Novo Nordisk (Liraglutide, Semaglutide), Eli Lilly (Tirzepatide) |
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OTC/Rx Status |
Prescription-only (Rx) |
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Post-Marketing Requirements |
Pharmacovigilance (PvPI) compliance required, regular safety monitoring by manufacturers |
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GLP-1 Agonists (Saxenda, Wegovy) Recognized as significant advancements in obesity treatment, offering substantial weight loss (10-15%+ of body weight). Physicians consider them "game-changers" for eligible patients due to their superior efficacy compared to other options like Orlistat.
Orlistat Viewed as effective for modest weight loss (5-10%), but its efficacy is highly dependent on patient adherence to a low-fat diet. Often seen as a "first-line but unsatisfactory" option due to gastrointestinal side effects.
Tirzepatide Dual-action drug, targeting both glucose metabolism and appetite regulation. It’s praised for its efficacy, but side effects and high cost are concerns.
Cost Barriers The prohibitive cost of Saxenda and the anticipated high price of Wegovy are major hurdles, with most physicians citing these drugs as inaccessible for over 95% of the Indian population. This has led to widespread off-label use of diabetes GLP-1 doses.
Need for Affordability Physicians emphasize the necessity for drastic price reductions, inclusion in public health schemes, or development of affordable biosimilars/generics for these drugs to have a real public health impact in India.
Orlistat Generally safe but causes gastrointestinal side effects (e.g., oily spotting, flatus, fecal urgency), which often lead to discontinuation. Long-term use may require monitoring for fat-soluble vitamin deficiencies.
GLP-1 Agonists (Saxenda, Wegovy, Tirzepatide) These drugs are generally well-tolerated, with side effects primarily involving nausea, vomiting, and, in some cases, gallbladder issues. Physicians are concerned about the potential for hypoglycemia in diabetic patients taking other glucose-lowering medications.
Lifestyle Foundation Physicians emphasize that no drug can replace the necessity of diet modification and physical activity. Medications should be considered adjuncts, not cures. Successful outcomes are reliant on lifestyle changes.
Patient Compliance There is frustration with patients seeking "magic pills" without commitment to lifestyle changes. Effective treatment requires careful patient selection based on BMI and comorbidities, along with managing patient expectations.
Personalization A personalized approach is crucial, with many physicians advocating for tailored treatment plans that consider individual needs and comorbidities.
Physicians are frustrated with the unregulated OTC "weight-loss" products, many of which are seen as ineffective or dangerous due to adulterants like Sibutramine, DNP, or steroids.
There is significant anticipation for the launch of Wegovy, with hopes that it will provide better efficacy and tolerability compared to Saxenda. Future treatments like oral GLP-1s and Tirzepatide are also anticipated but tempered by concerns over cost and accessibility.
Anti-obesity drugs are generally seen as effective when combined with lifestyle modifications. However, concerns around side effects, cost, and patient adherence remain significant. Personalized treatment and better education for physicians on obesity management are key to improving treatment outcomes.

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| Report Coverage | Details | ||
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| Base Year: | 2024 | Market Size in 2025: | USD 25.87 Bn |
| Historical Data for: | 2020 To 2024 | Forecast Period: | 2025 To 2032 |
| Forecast Period 2025 to 2032 CAGR: | 18.01% | 2032 Value Projection: | USD 82.55 Bn |
| Geographies covered: |
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| Segments covered: |
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| Companies covered: |
Novo Nordisk, GlaxoSmithKline, AstraZeneca, Pfizer, Merck & Co., Sanofi, Amgen, Eli Lilly and Company, Johnson & Johnson, Takeda Pharmaceutical Company, Abbott Laboratories, Orexigen Therapeutics, Zafgen, Rhythm Pharmaceuticals, and Currax Pharmaceuticals |
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| Growth Drivers: |
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| Restraints & Challenges: |
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The escalating prevalence of obesity worldwide has emerged as a significant factor propelling the demand for anti-obesity medications. Urbanization, sedentary lifestyles, unhealthy dietary patterns, and genetic predispositions have collectively contributed to a steady rise in obesity rates across diverse age groups and regions. As obesity is closely linked with numerous chronic conditions such as type 2 diabetes, cardiovascular diseases, and certain cancers, there is an increasing urgency among healthcare providers and patients to seek effective treatment options beyond conventional lifestyle modifications. This growing health concern has heightened awareness about the benefits of pharmacological interventions, encouraging individuals who struggle with weight management to turn to anti-obesity drugs as adjunct therapy.
For instance, in May 2025, according to the WHO, 1 in 8 people globally were living with obesity, with 2.5 billion adults overweight, including 890 million with obesity. The prevalence of obesity has more than doubled since 1990, while adolescent obesity has quadrupled. In children, 390 million were overweight, with 160 million living with obesity. Obesity significantly increases the risk of diseases like diabetes, heart disease, and certain cancers. The condition is diagnosed using Body Mass Index (BMI), with overweight defined as a BMI of 25 or greater, and obesity as 30 or greater in adults. The global rise in obesity, particularly in low- and middle-income countries, poses serious health challenges.
The global anti-obesity drug market is experiencing significant opportunities due to the growing prevalence of obesity and an increasing demand for safer, more effective, and patient-friendly treatments. Advancements in pharmaceutical technology and a better understanding of obesity's complex causes have led to innovative drug formulations. These include extended-release formulations, combination therapies, and targeted molecular treatments designed to improve efficacy, minimize side effects, and enhance patient adherence.
A notable example of these developments is Eli Lilly’s Mounjaro KwikPen, which received approval from India's Central Drugs Standard Control Organization (CDSCO) on June 26, 2025. This once-weekly prefilled injector, designed for both type 2 diabetes and obesity, expands the drug's availability from the initial 2.5mg and 5mg vials to include six strengths (2.5, 5, 7.5, 10, 12.5, and 15mg). The new KwikPen offers a more personalized and convenient dosing option, reflecting the broader trend in the industry towards more adaptable and user-friendly drug delivery systems.
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About Author
Ghanshyam Shrivastava - With over 20 years of experience in the management consulting and research, Ghanshyam Shrivastava serves as a Principal Consultant, bringing extensive expertise in biologics and biosimilars. His primary expertise lies in areas such as market entry and expansion strategy, competitive intelligence, and strategic transformation across diversified portfolio of various drugs used for different therapeutic category and APIs. He excels at identifying key challenges faced by clients and providing robust solutions to enhance their strategic decision-making capabilities. His comprehensive understanding of the market ensures valuable contributions to research reports and business decisions.
Ghanshyam is a sought-after speaker at industry conferences and contributes to various publications on pharma industry.
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