Global Cryoablation Devices Market, By Device Type (Systems, Probes), Application (Prostate Cancer, Renal Cancer, Liver Cancer, Breast Cancer), End User (Hospitals, Ambulatory Surgical Centers, Surgical Clinics), and Geography - Insights, Size, Share, Opportunity Analysis, and Industry Forecast till 2025

Cryoablation Devices – Rising Demand for Complex Procedures

Many of the primary hepatic cancers are classified as hepatocellular carcinoma. When a cells resembling the hepatocytes aggregates and forms tumor that is called as hepatocellular carcinoma, which is a malignant tumor. However, the resemblance may vary with the intensity of differentiation. Liver cirrhosis is expected to be closely related to the hepatocellular carcinoma, which is potentially a curable form of tumor and can be treated by surgical resection. However, only such patients those who are having localized disease are surgical candidates. Furthermore, impairment of liver function and degree of localization of the tumor determine patient prognosis proliferation. The various clinical trials offers an alternative treatment options for different patients who are not candidates for resection.

According to the World Health Organization (WHO), the number of new cancer cases is expected to increase by 70% by 2030 as compared to 2012. This increase in cancer cases will support growth of cryoablation devices market, as cryoablation is a preferred treatment for cancer. The change in lifestyle and unhealthy eating habits, along with increasing consumption of tobacco and alcohol is the leading cause for growth in number of cancer cases. As per stats released by National Cancer Institute (NCI), around 1,685,210 new cases of cancer were diagnosed in the U.S. in 2016. According to WHO, cancer was the cause for 8.8 million deaths in 2015.As cryoablation devices have more specificity and help curtail growth of targeted cells effectively, demand for these devices is increasing year-on-year in both developed as well as emerging economies for treatment of cancer. As cryoablation procedure avoids major surgery and thus, has low patient recovery time, it is gaining traction across the globe. The market is expected to gain significant traction in emerging economies of Asia Pacific, due to projected spurt in number of cancer cases detected in the region. According to American Cancer Society, 4.3 million new cancer cases were reported in China in 2015 and this number is continuously increasing year-on-year.

Rising demand for cryoablation for complex procedures and rising geriatric population are expected to favor the growth in the adoption rate for cryoablation procedures around the globe over the forecast period

Economies of China and Japan are among the largest markets for cryoablation devices, given their large geriatric population. Cryoablation, being a minimally-invasive procedure, is highly recommended for treatment of elderly people, characterized by a weaken immune system. As per United Nations Department of Economic and Social Affairs (U.N. DESA), there were 125 million people aged 80 years or over in 2015, which is expected to increase to 434 million by 2050. Furthermore, the number of people aged 60 years or over is estimated to grow by 56% between 2015 and 2030. This rise in number of aged population will support the growth of cryoablation devices market through increase in use of cryoablation devices for the treatment of elder people who cannot undergo open heart surgery.

The global cryoablation devices market is estimated to be valued at US$ 122.1 Mn in 2017 and is expected to witness a robust CAGR of 8.5% during the forecast period (2017 – 2025).

Global Cryoablation Devices Market Analysis, By Application – 2016 & 2025

cryoablation devices market

Source: Coherent Market Insights (2017)

Increase in incidence of cancer is expected to create significant market opportunity for players in the cryoablation devices market

According to W.H.O, in 2017, cancer is one of the leading causes for morbidity and mortality around the globe, with around 14 million cases in 2012, the number of new cancer cases is expected to increase by 70% by 2030. Also as per American Cancer Society, in 2016 estimated 1,685,210 new cancer cases were observed in U.S. The market is expected to gain significant traction in emerging economies of Asia Pacific, due to projected spurt in number of cancer cases detected in the region. According to American Cancer Society, 4.3 million new cancer cases were reported in China in 2015. This increase in cancer cases will support the growth of cryoablation devices market in the future.

As cryoablation devices have more specificity and help curtail growth of targeted cells effectively, demand for these devices is increasing year-on-year for the treatment of cancer, also the market players have opportunity to develop technically advanced devices and tap into major lucrative market in North America, which has recently witnessed the approval of these devices for cancer treatment.

Increase in incidence of cardiac disorders such as cardiac arrhythmia, atrial fibrillation, and atrial flutter expected to fuel the growth in cryoablation devices market

According to Centers for Disease Control and Prevention (CDC), every year, around 610,000 people die due to heart disease in the U.S. Furthermore, around 2.7 to 6.1 million people were suffering from atrial fibrillation in 2013-14 in the U.S., the high incidence of cardiac disorders such as cardiac arrhythmia, atrial fibrillation, and atrial flutter is the another factor leading to the growth of cryoablation devices market.

The growing aging population and obesity rate are the major risk factor for atrial fibrillation. As per W.H.O., worldwide obesity has more than doubled and it is reached to more than 1.9 billion obese population in 2014 from 1980, as well as around 41 million children under the age of 5 were obese in 2014 and this number is continuously on rise in emerging countries. As per the stats of W.H.O. around 10.6 million children who are obese found in Africa in 2014, also close to half of the children under 5 who were obese lived in Asia in 2014. This increase in number of obese population in emerging countries will support to expand the customer base for companies in untapped market.

Some of the major companies in cryoablation devices market are Medtronic Inc, Galil Medical Inc, AtriCure, Inc., IceCure Medical and Sanarus Technologies.

Cryotherapy and radiofrequency ablation (RFA) are the two clinically viable ablation modalities that are widely used and cryotherapy is a treatment that uses extreme cold for denaturing the diseased tissues in the human body. In cryoablation therapy, liquid nitrogen or argon gas is passed to the site of treatment using a probe, which creates intense cold that freezes the internal tumors. The procedure is often carried out multiple times till the affected tissue is totally destroyed. The technique yields high effectiveness for treatment of various tumors such as that in the bones, kidneys, breasts, lungs, and liver, and can also be used to treat certain skin conditions. The probe is guided using MRI and ultrasound, which locates the exact position of the affected tissue that proves the specificity of the therapy.

The cryoablation therapy has many applications in various disease such as renal cancer, prostate cancer, breast cancer, liver cancer and cardiac arrhythmias. Adoption of cryoablation procedures is growing as cryoablation is a minimally invasive procedure that avoids major surgery and thus, allows for rapid recovery of the patient. Percutaneous procedure used for the therapy, involves use of a thin needle size probe that is inserted in the body through a small incision.

In 2017, according to Radcliffe Cardiology, for various cardiac arrhythmias cryoablation process worldwide for treating cardiac arrhythmia is now being considered as a safe and efficiently effective alternate to radio frequency ablation.

Cryoablation Devices Market Dynamics

Cryoablation is a minimally invasive procedure that avoids major surgery and helps to avoid the complexity and heavy blood loss during the treatment and patient can resume his daily activities within very less time after the procedure. Therefore the preference for cryoablation treatment is increasing year on year. Also, the cryoablation procedure is beneficial to both the surgeon and patient as regular surgical procedure requires around 1 hour, while cryoablation is a 10-30 minutes procedure. Also, the length of incision in conventional surgery is around 10 mm, while cryoablation requires an incision of only 2 mm. Also, cryoablation do not require general anesthesia.

Continuous development and innovation into probes are expected to favor increase in adoption rate for cryoablation devices in the near future. Increase in geriatric population is expected to be a major push for the market to grow in emerging countries such as China, according to United Nations Department of Economic and Social Affairs (U.N. DESA), there were 125 million people aged 80 years or over in 2015, which is expected to increase to 434 million by 2050. This rise in geriatric population will support the growth of cryoablation devices for the treatment of the elderly people who cannot undergo open heart surgery.

Market Taxonomy

This report segments the global cryoablation devices market on the basis of device type, application, end user and geography. On the basis of device type, the market is categorized into systems and probes. Among these, probes segment dominate the cryoablation devices market. On the basis of application, the market is divided into prostate cancer, renal cancer, liver cancer, breast cancer and cardiac arrhythmia. On the basis of geography, the market is divided into 6 regions. Among all regions, North America dominated the cryoablation devices market, as the hospitals are early adopters cryoablation system and the availability of funds to invest amount in the installation of cryoablation system are the major factor behind the growth of cryoablation devices market in this region.

Key features of the study:

  • This report provides in-depth analysis of the cryoablation devices market and provides market size (US$ Mn) and Cumulative Annual Growth Rate (CAGR) (%) for the forecast period (2017–2025)
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market. It provides valuable insights about market drivers, restraints, opportunities, new product launches or approval, pipeline technologies, regional outlook, and competitive strategy adopted by the leading players
  • It profiles leading players in the global cryoablation devices market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, key developments, and future plans
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions with respect to their future product launch, market expansion, and marketing tactics
  • The global cryoablation devices market report caters to various stakeholders in this industry, including investors, product developers, distributors, healthcare companies, research institutes, medical device companies, new entrants, and financial analysts
  • Stakeholders would greatly benefit in decision making through the various strategy matrices used in analyzing the cryoablation devices market

Detailed Segmentation:

  • Global Cryoablation Devices Market, By Device Type:
    • Systems
    • Probes
  • Global Cryoablation Devices Market, By Application:
    • Prostate Cancer
    • Renal Cancer
    • Liver Cancer
    • Breast Cancer
  • Global Cryoablation Devices Market, By End User:
    • Hospitals
    • Ambulatory Surgical Centers
    • Surgical Clinics
  • Global Cryoablation Devices Market, By Geography:
    • North America
      • North America Cryoablation Devices Market, By Device Type:
        • Systems
        • Probes
      • North America Cryoablation Devices Market, By Application:
        • Prostate Cancer
        • Renal Cancer
        • Liver Cancer
        • Breast Cancer
      • North America Cryoablation Devices Market, By End User:
        • Hospitals
        • Ambulatory Surgical Centers
        • Surgical Clinics
      • North America Cryoablation Devices Market, By Country:
        • U.S.
        • Canada
    • Europe
      • Europe Cryoablation Devices Market, By Device Type:
        • Systems
        • Probes
      • Europe Cryoablation Devices Market, By Application:
        • Prostate Cancer
        • Renal Cancer
        • Liver Cancer
        • Breast Cancer
      • Europe Cryoablation Devices Market, By End User:
        • Hospitals
        • Ambulatory Surgical Centers
        • Surgical Clinics
      • Europe Cryoablation Devices Market, By Country:
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia-Pacific
      • Asia-Pacific Cryoablation Devices Market, By Device Type:
        • Systems
        • Probes
      • Asia-Pacific Cryoablation Devices Market, By Application:
        • Prostate Cancer
        • Renal Cancer
        • Liver Cancer
        • Breast Cancer
      • Asia-Pacific Cryoablation Devices Market, By End User:
        • Hospitals
        • Ambulatory Surgical Centers
        • Surgical Clinics
      • Asia-Pacific Cryoablation Devices Market, By Country:
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia-Pacific
    • Latin America
      • Latin America Cryoablation Devices Market, By Device Type:
        • Systems
        • Probes
      • Latin America Cryoablation Devices Market, By Application:
        • Prostate Cancer
        • Renal Cancer
        • Liver Cancer
        • Breast Cancer
      • Latin America Cryoablation Devices Market, By End User:
        • Hospitals
        • Ambulatory Surgical Centers
        • Surgical Clinics
      • Latin America Cryoablation Devices Market, By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Middle East
      • Middle East Cryoablation Devices Market, By Device Type:
        • Systems
        • Probes
      • Middle East Cryoablation Devices Market, By Application:
        • Prostate Cancer
        • Renal Cancer
        • Liver Cancer
        • Breast Cancer
      • Middle East Cryoablation Devices Market, By End User:
        • Hospitals
        • Ambulatory Surgical Centers
        • Surgical Clinics
      • Middle East Cryoablation Devices Market, By Country:
        • GCC
        • Israel
        • Rest of Middle-East
    • Africa
      • Africa Cryoablation Devices Market, By Device Type:
        • Systems
        • Probes
      • Africa Cryoablation Devices Market, By Application:
        • Prostate Cancer
        • Renal Cancer
        • Liver Cancer
        • Breast Cancer
      • Africa Cryoablation Devices Market, By End User:
        • Hospitals
        • Ambulatory Surgical Centers
        • Surgical Clinics
      • Africa Cryoablation Devices Market, By Country:
        • North Africa
        • Central Africa
        • South Africa
  • Company Profiles
    • Medtronic Inc. *
      • Company Overview
      • Product Portfolio
      • Strategies Presence
      • Key Developments
      • Market Presence
      • Investment Raised
      • Marketing and Promotional Activities
    • Galil Medical Inc.
    • AtriCure, Inc.
    • IceCure Medical
    • Sanarus Technologies

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet By Different Segments
      • Coherent Attractive Investment Proposition and Total Addressable Market
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers, Restraints and Opportunities
      • Regulatory Scenario
      • Market Trends
      • PEST Analysis
  4. Global Cryoablation Devices Market, By Device Type, 2016 - 2025 (US$ Million)
    • Introduction
      • Market Share Analysis, 2017 and 2025 (%)
      • Y-O-Y Growth Analysis, 2016 - 2025
      • Segment Trends
    • Systems
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2016 - 2025, (US$ Million)
    • Probes
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2016 - 2025, (US$ Million)
  5. Global Cryoablation Devices Market, By Application, 2016 - 2025 (US$ Million)
    • Introduction
      • Market Share Analysis, 2017 and 2025 (%)
      • Y-O-Y Growth Analysis, 2016 - 2025
      • Segment Trends
    • Prostate Cancer
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2016 - 2025, (US$ Million)
    • Renal Cancer
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2016 - 2025, (US$ Million)
    • Liver Cancer
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2016 - 2025, (US$ Million)
    • Breast Cancer
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2016 - 2025, (US$ Million)
    • Cardiac Arrhythmia
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2016 - 2025, (US$ Million)
  6. Global Cryoablation Devices Market, By End User, 2016 - 2025 (US$ Million)
    • Introduction
      • Market Share Analysis, 2017 and 2025 (%)
      • Y-O-Y Growth Analysis, 2016 - 2025
      • Segment Trends
    • Hospitals
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2016 - 2025, (US$ Million)
    • Ambulatory Surgical Centers
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2016 - 2025, (US$ Million)
    • Surgical Clinics
      • Introduction
      • Market Size and Forecast, and Y-O-Y Growth, 2016 - 2025, (US$ Million)
  7. Global Cryoablation Devices Market, By Geography, 2016 - 2025 (US$ Million)
    • Introduction
      • Market Share Analysis, By Geography, 2017 and 2025 (%)
      • Y-O-Y Growth Analysis, 2014 – 2024
      • Regional Trends
    • North America
      • Introduction
      • Market Share Analysis, By Country, 2017 and 2025 (%)
      • Country Trends
      • Market Size and Forecast, and Y-o-Y Growth, 2014-2024, (USD Million)
        • U.S.
        • Canada
    • Europe
      • Introduction
      • Market Share Analysis, By Country, 2017 and 2025 (%)
      • Country Trends
      • Market Size and Forecast, and Y-o-Y Growth, 2014-2024, (USD Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Introduction
      • Market Share Analysis, By Country, 2017 and 2025 (%)
      • Country Trends
      • Market Size and Forecast, and Y-o-Y Growth, 2014-2024, (USD Million)
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Introduction
      • Market Share Analysis, By Country, 2017 and 2025 (%)
      • Country Trends
      • Market Size and Forecast, and Y-o-Y Growth, 2014-2024, (USD Million)
        • Brazil
        • Argentina
        • Rest of Latin America
    • Middle East
      • Introduction
      • Market Share Analysis, By Country, 2017 and 2025 (%)
      • Country Trends
      • Market Size and Forecast, and Y-o-Y Growth, 2014-2024, (USD Million)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Introduction
      • Market Share Analysis, By Country, 2017 and 2025 (%)
      • Country Trends
      • Market Size and Forecast, and Y-o-Y Growth, 2014-2024, (USD Million)
        • North Africa
        • Central Africa
        • South Africa
  8. Competitive Landscape
    • Company Profiles
      • Medtronic Inc.
        • Company Highlights
        • Key Developments
        • Product Portfolio
        • Market Presence
        • Investment Raised
        • Marketing and Promotional Activities
        • Strategic Presence
      • Galil Medical Inc.
        • Company Highlights
        • Key Developments
        • Product Portfolio
        • Market Presence
        • Investment Raised
        • Marketing and Promotional Activities
        • Strategic Presence
      • AtriCure, Inc.
        • Company Highlights
        • Key Developments
        • Product Portfolio
        • Market Presence
        • Investment Raised
        • Marketing and Promotional Activities
        • Strategic Presence
      • IceCure Medical
        • Company Highlights
        • Key Developments
        • Product Portfolio
        • Market Presence
        • Investment Raised
        • Marketing and Promotional Activities
        • Strategic Presence
      • Sanarus Technologies
        • Company Highlights
        • Key Developments
        • Product Portfolio
        • Market Presence
        • Investment Raised
        • Marketing and Promotional Activities
        • Strategic Presence
    • Analyst Views
  9. Section
    • Research Methodology
    • About us and Services

*Browse 25 market data tables and 27 figures on "Cryoablation Devices Market - Global forecast to 2025”.

Research Methodology

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  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
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The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
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Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
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  • Distributors
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