Global Dental Bone Graft and Substitutes Market by Product Type (Demineralized Bone Matrix (DBM), Allograft, Xenograft, and Synthetic Bone Graft Substitutes), by Material Type (Collagen, Human Cell Source, Animal Source, Hydroxyapatite (Ha), Tricalcium Phosphate (TCP), and Others), by End User (Hospitals, Clinics, and Ambulatory Surgery Centers) and by Geography - Trends and Forecast to 2025

  • Published On : Jan 2018 |
  • Pages : 150 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Dental Bone Graft and Substitutes Market Insights

Dental bone grafts are used as fillers or scaffolds that facilitate bone formation and helps in the wound healing and are suitable for a variety of clinical procedures such as filling of sockets, preservation of ridge volume (also referred to as ridge preservation), and osteogenesis i.e., the formation of new bones. Dental bone grafts are bioresorbable and are not reactive to antigen-antibody. Bone grafts are capable of restoring functionality without intervening aesthetic appearance and can be placed at different locations in the buccal cavity for several indications such as to refill a local bony effect as a result of infection or trauma, and to refill a peri-implant defect caused due to peri-implantitis. Dental bone grafts may be autogenous, allogenous, and xenogenous, whereas, effective alternatives such as synthetic bone grafts are also available. These include demineralized bone matrix, hydroxyapatite, and collagen based matrices, which provide various advantages over dental bone grafts. For instance, ReproBone bone graft substitute, which offers sterility, integrity, and improved stability at the surgical site. Commercially available dental bone grafts and substitutes include Grafton DBM, MinerOss, and NovaBone among others. The risks associated with surgery failure and graft failure can act as a potential barrier for people to maintain faith in the success rate of these devices. According to Dental-Implants-01, the dental bone graft failure rates range from 5-10% on an average, as a result of infections and improper stabilization of the grafts. Thus, the failure of implantation can cause a threat to growth of the global dental bone graft and substitutes market

Development of novel bone graft substitutes is expected to boost growth of the dental bone graft and substitutes market

The global bone graft and substitutes market is expected to witness a significant growth over the forecast period, owing to adoption of new technologies by manufacturers for development of innovative and novel bone graft substitutes. Alternative bone graft to autografts such as allografts are gaining popularity. This is owing to requirement of single incision for implantation of allograft, whereas, autograft requires two incisions. This reduces the surgery time and hence is increasingly being adopted. Increasing demand for allografts, xenografts, and various other synthetic bone grafts due to their wide availability and advantages such as high stability and low chances of infection at site, is a factor expected to compliment the market growth. For instance, increasing use of hydroxyapatite in bone grafts due to advantages such as high stability, integrity, and less chances of infection is aiding in market growth. Synthetic materials facilitating improved handling are preferred in most bone grafting procedures. Synthetic bone grafts are beneficial, owing to high availability as well as reducing risks of injuries to the donor site. Development of novel bone graft substitutes such as i-FACTOR and increasing application of these substitutes in dental procedures is expected to support in the market growth. Thus, biotechnology-based products that do not interfere with the natural growth process are expected to gain rampant traction over the forecast period.

The global dental bone graft and substitutes market was valued at US$ 418.4 million in 2016 and is expected to witness a robust CAGR of 9.1% over the forecast period (2017–2025).

Dental Bone Graft

   Source: Coherent Market Insights Analysis (2017)

Increasing medical tourism is expected to aid in growth of the global dental bone graft and substitutes market over the forecast period

Advancements in bone graft substitutes has provided better alternative to bone grafts for patients, however, high cost has limited its adoption among price sensitive customers. Developed regions such as North America and Europe have presence of innovative product manufacturers in this product space. However, the costs of the products as well as the procedural costs for in the hospitals in these regions are comparatively higher than that in the emerging economies such as  India, China, and Brazil which may prove to be primary driving factor for growth in this market. According to OrthoStreams, orthopedic surgeries in China and other emerging economies is 75% cheaper as compared to that of the procedures performed in the U.S. Hospitals in emerging economies have access to advanced technologies and skilled surgeons to perform the procedure with same level of precision as that in developed countries. Costs associated with any surgical procedures are lower in emerging economies such as India as overall cheaper costs for everything associated with such procedures depending on complexity of the surgeries. Furthermore, hospitals use locally manufactured graft and graft substitutes for bone grafting procedures that provide equivalent levels of performance to that of the globally available commercial bone graft substitutes. According to International Journal of Pharmaceutical Sciences Review and Research, 2015, dental surgeries cost three to four times more in developed regions than in India. Thus, a large patient pool migrates to India so as to avail bone grafting procedures, leading to growth of the dental bone graft and substitutes market in Asia Pacific.

Some major players operating in the dental bone graft and substitutes market are Institut Straumann AG, Geistlich, DENTSPLY International, Zimmer Biomet, Medtronic Plc., BioHorizons IPH, Inc., ACE Surgical Supply Company, Inc., RTI Surgical, Inc., LifeNet Health, and Citagenix

Bone grafting is replacement of damaged part of dental structure with the help of grafts such as autografts, allograft or xenograft. Patients with teeth missing need to undergo a dental implant procedure, however, if their jaw bone is thin or soft and is not able to hold the dental implant in its place, then they need to undergo a bone graft procedure. Synthetic substitutes such as Hydroxyapatite (HA) and Tricalcium Phosphate (TCP) are also been used in dental procedures. Various factors for dental deformities include gum disease, traumas, injuries, accidents, and genetic defects. Bone grafts offer various advantages such as preserving the structure and strength of the jaw bone, avoids the possibility of narrow and fragile jaw bone.

Market Dynamics

Bone graft materials are available in varieties such as allografts, xenografts, and synthetic substitutes and can be custom made according to the need of the patient, which makes it convenient for both, the physician and patient driving the growth of the market. Bone grafts are widely available from various sources such as from patients, from another donor, from animal sources, or are synthetically made. Furthermore, advancements in technology has led to development of synthetic graft options with better stability, sterility, and long life. These advancements have reduced surgical times along with post-operative pain and have improved healing time increasing adoption of these substitutes which has impacted the market. Development of biocompatible bone grafts such as B-OstiN and hydroxyapatite allografts and advent of different variants is a factor expected to fuel growth of the global dental bone graft substitutes market over the forecast period.

Key features of the study:

  • This report provides an in-depth analysis of dental bone graft and substitutes market and provides market size (US$ Million) and Cumulative Annual Growth Rate (CAGR %) for the forecast period (2017–2025), considering 2016 as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, regional outlook, and competitive strategy adopted by the leading players
  • It profiles leading players in the global dental bone graft and substitutes market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies
  • Key companies covered as a part of this study include Institut Straumann AG, Geistlich, DENTSPLY International, Zimmer Biomet, Medtronic Plc., BioHorizons IPH, Inc., ACE Surgical Supply Company, Inc., RTI Surgical, Inc., and LifeNet Health, Citagenix
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decision regarding their future product launches, technology up-gradation, market expansion, and marketing tactics
  • The global dental bone graft and substitutes market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through the various strategy matrices used in analyzing the dental bone graft and substitutes market

Detailed Segmentation:

  • Global Dental Bone Graft and Substitutes Market, By Product Type:
    • Demineralized Bone Matrix (DBM)
    • Allograft
    • Xenograft
    • Synthetic Bone Graft Substitutes
  • Global Dental Bone Graft and Substitutes Market, By Material Type:
    • Collagen
    • Human Cell Source
    • Animal Source
    • Hydroxyapatite (HA)
    • Tricalcium Phosphate (TCP)
    • Others
  • Global Dental Bone Graft and Substitutes Market, By End User:
    • Hospitals
    • Clinics
    • Ambulatory Surgery Centers
  • Global Dental Bone Graft and Substitutes Market, By Geography:
    • North America
      • By Product Type:
        • Demineralized Bone Matrix (DBM)
        • Allograft
        • Xenograft
        • Synthetic Bone Graft Substitutes
      • By Material Type:
        • Collagen
        • Human Cell Source
        • Animal Source
        • Hydroxyapatite (HA)
        • Tricalcium Phosphate (TCP)
        • Others
      • By End User:
        • Hospitals
        • Clinics
        • Ambulatory Surgery Centers
      • By Country:
        • U.S.
        • Canada
    • Europe
      • By Product Type:
        • Demineralized Bone Matrix (DBM)
        • Allograft
        • Xenograft
        • Synthetic Bone Graft Substitutes
      • By Material Type:
        • Collagen
        • Human Cell Source
        • Animal Source
        • Hydroxyapatite (HA)
        • Tricalcium Phosphate (TCP)
        • Others
      • By End User:
        • Hospitals
        • Clinics
        • Ambulatory Surgery Centers
      • By Country:
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Product Type:
        • Demineralized Bone Matrix (DBM)
        • Allograft
        • Xenograft
        • Synthetic Bone Graft Substitutes
      • By Material Type:
        • Collagen
        • Human Cell Source
        • Animal Source
        • Hydroxyapatite (HA)
        • Tricalcium Phosphate (TCP)
        • Others
      • By End User:
        • Hospitals
        • Clinics
        • Ambulatory Surgery Centers
      • By Country:
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • By Product Type:
        • Demineralized Bone Matrix (DBM)
        • Allograft
        • Xenograft
        • Synthetic Bone Graft Substitutes
      • By Material Type:
        • Collagen
        • Human Cell Source
        • Animal Source
        • Hydroxyapatite (HA)
        • Tricalcium Phosphate (TCP)
        • Others
      • By End User:
        • Hospitals
        • Clinics
        • Ambulatory Surgery Centers
      • By Country:
        • Brazil
        • Mexico
        • Rest of Latin America
    • Middle East
      • By Product Type:
        • Demineralized Bone Matrix (DBM)
        • Allograft
        • Xenograft
        • Synthetic Bone Graft Substitutes
      • By Material Type:
        • Collagen
        • Human Cell Source
        • Animal Source
        • Hydroxyapatite (HA)
        • Tricalcium Phosphate (TCP)
        • Others
      • By End User:
        • Hospitals
        • Clinics
        • Ambulatory Surgery Centers
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Product Type:
        • Demineralized Bone Matrix (DBM)
        • Allograft
        • Xenograft
        • Synthetic Bone Graft Substitutes
      • By Material Type:
        • Collagen
        • Human Cell Source
        • Animal Source
        • Hydroxyapatite (HA)
        • Tricalcium Phosphate (TCP)
        • Others
      • By End User:
        • Hospitals
        • Clinics
        • Ambulatory Surgery Centers
      • By Country:
        • Central Africa
        • South Africa
        • North Africa
  • Company Profiles
  • The Straumann Group*
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Key Strategies
      • Recent Developments
  • Geistlich
  • DENTSPLY International
  • Zimmer Biomet
  • Medtronic Plc.
  • BioHorizons IPH, Inc.
  • ACE Surgical Supply Company, Inc.
  • RTI Surgical, Inc.
  • LifeNet Health
  • Citagenix

 “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet By Product Type
      • Market Snippet By Material Type
      • Market Snippet By End User
      • Market Snippet By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • PEST Analysis
    • PORTER’s Five Forces Analysis
    • Regulatory Scenario
    • Market Trends
    • Technological Evolution
  4. Global Dental Bone Graft and Substitutes Market, By Product Type, 2015 - 2025 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2016 and 2025 (%)
      • Y-o-Y Growth Analysis, 2017 - 2025
      • Segment Trends
    • Demineralized Bone Matrix (DBM)
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
    • Allograft
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
    • Xenograft
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
    • Synthetic Bone Graft Substitutes
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
  5. Global Dental Bone Graft and Substitutes Market, By Material Type, 2015 - 2025 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2016 and 2025 (%)
      • Y-o-Y Growth Analysis, 2017 - 2025
      • Segment Trends
    • Collagen
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
    • Human Cell Source
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
    • Animal Source
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
    • Hydroxyapatite (HA)
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
    • Tricalcium Phosphate (TCP)
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
  6. Global Dental Bone Graft and Substitutes Market, By End User, 2015 - 2025 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2016 and 2025 (%)
      • Y-o-Y Growth Analysis, 2017 - 2025
      • Segment Trends
    • Hospitals
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
    • Clinics
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
    • Ambulatory Surgery Centers
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2017 - 2025, (US$ Mn)
  7. Global Dental Bone Graft and Substitutes Market, By Regions, 2015 - 2025 (US$ Mn)
    • Introduction
      • Market Share Analysis, By Region, 2016 and 2025 (%)
      • Y-o-Y Growth Analysis, For Regions, 2017 - 2025
    • North America
      • Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Material Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By End User, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Material Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By End User, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Material Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By End User, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
        • China
        • India
        • Japan
        • ASEAN
        • Australia
        • South Korea
        • Rest of APAC
    • Latin America
      • Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Material Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By End User, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
        • Brazil
        • Mexico
        • Rest of Latin America
    • Africa
      • Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Material Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By End User, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
        • Central Africa
        • South Africa
        • North Africa
    • Middle East
      • Market Size and Forecast, By Product Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Material Type, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By End User, 2015 - 2025 (US$ Mn)
      • Market Size and Forecast, By Country, 2015 - 2025 (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
  8. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • Institut Straumann AG
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Key Strategies
        • Recent Developments/Updates
      • Geistlich
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Key Strategies
        • Recent Developments/Updates
      • DENTSPLY International
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Key Strategies
        • Recent Developments/Updates
      • Zimmer Biomet
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Key Strategies
        • Recent Developments/Updates
      • Medtronic Plc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Kay Strategies
        • Recent Developments/Updates
      • BioHorizons IPH, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Key Strategies
        • Recent Developments/Updates
      • ACE Surgical Supply Company, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Key Strategies
        • Recent Developments/Updates
      • RTI Surgical, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Key Strategies
        • Recent Developments/Updates
      • LifeNet Health
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Key Strategies
        • Recent Developments/Updates
      • Citagenix
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Key Strategies
        • Recent Developments/Updates
      • NovaBone
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Key Strategies
        • Recent Developments/Updates
  9. Section
    • References
    • Research Methodology
    • About us and Sales Contact

*Browse 40 market data tables and 66 figures on "Dental Bone Graft and Substitutes Market - Global forecast to 2025”.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
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