Granulators for Pharmaceutical Market, by Product Type (Single Pot Granulators, High Sheer Granulators, Fluid Bed Granulators, Rapid Mixer Granulators, Oscillating Granulators and Others), by Application (End Product Manufacturing, Solid Dosage Formulation, API Manufacturing, and Others), By Granulation Mechanism (Dry Granulators, Wet Granulators and Mixed Granulators), By End User (Pharmaceutical Manufacturing Companies, Contract Manufacturing Organizations, Research Institutes, and Others), and By Region - Global Forecast to 2025
- Report code : CMI41649 |
- Industry :
Medical Devices
- Published On : May 2018 |
- Pages : 224 Pages |
- Format :
Granulators for Pharmaceutical Market – The Story of Pill Formation
Granulators are rotor machines that converts fine powder to granules via a series of physical process. Granulation is process in which small particles are gathered together to form a large permanent mass, which can identify original particles. The granulation has applications in pharmaceutical drug manufacturing for making of tablets, capsules, and other forms of medicines. The granulated material is obtained by size enlargement of primary particles or size reduction from dry compacted material. The multi-particle entities that are formed as a result of granulation creates bond between the particles through compression with the help of a binding agent. Granulation is one of the most important unit operations involved in the production of pharmaceutical oral dosage forms. Furthermore, granulation is carried out with the help of granulators that are available in different technologies. The pharmaceutical drug manufacturing companies choose one of these granulators based on the demand from the drug and its formulation. They help to deliver correct form of dosage and maintain the chemical integrity of pharmaceutical product. The expansion of pharmaceutical manufacturing units and new pharmaceutical players entering in the market are the primary factors responsible for growth of the granulators for pharmaceutical market. For instance, in 2013, the Supreme Council of Health Pharmacy and Drug Control Department of Qatar announced three new domestic drug manufacturers to cut down on drug importing and start production within the economy for a number of drugs and vaccines.
The global granulators for pharmaceutical market was valued at US$ 5,486.44 million in 2016 and is expected to witness a steady CAGR of 5.40% over the forecast period (2017 - 2025).
Figure 1. Global Granulators for Pharmaceutical Market (US$ Mn), by Region, 2016
Source: Coherent Market Insights (2018)
Several initiatives taken by governmental and non-governmental organization to scale up pharmaceutical manufacturing process leading to number of new and existing players entering the production sector are major factors driving the market growth. The entry of local players in the pharmaceutical industry is accompanied by funding and subsidies provided to these players in terms of facility & equipment set-up helps the companies to start small and mid-sized manufacturing units. Granulators are an integral part of these units, as these are the primary stage unit processors in oral dosage formulations. For instance, according to the provisions of 2015 - 16 Union Budget of India, a national center to develop bulk drugs and facilitate their research was set up in Hyderabad. Automation of drug development procedure involves installation of upgraded automatic instruments, which is propelling demand for pharmaceutical granulators. For instance, in July 2017 Boehringer Ingelheim invested US$ 217 Million to upgrade and expand its manufacturing facility in Fremont, California. Furthermore, in 2012 the new release for GMP upgrade of a production facility for solid pharmaceuticals includes procurement of new production equipment such as granulator and dryer, capsule deduster, and others.
In terms of region, North America dominated the global granulators for pharmaceutical market, owing to presence of leading pharmaceutical manufacturers in the region with huge production plants that involve mass manufacturing and development of oral pharmaceutical drugs. Moreover, the production facility expansion by existing pharmaceutical players and startup of new production plant by emerging market players in the pharmaceutical industry are also contributing to growth of North America region in the granulators market. In September 2017, Fresenius Kabi announced an investment of US$ 250 million investment to establish a pharmaceutical plant in Illinois for aseptic manufacturing of pharmaceutical drugs in the company’s portfolio. In March 2017, Apotex, Inc. a Canadian pharmaceutical company announced an investment of US$ 184 million for expansion of advanced manufacturing and R&D facility in Florida. Moreover, Asia Pacific is expected to witness a significant traction in the granulators market, owing to major investments by global and regional pharmaceutical players for expansion of the production units. For instance, in March 2018, Merck KGaA invested US$ 47 million for expansion of manufacturing plants in South Korea and India to develop biologics and other pharmaceutical drugs. Furthermore, emerging economies in Asia Pacific such as India has a considerable manufacturing expertise and holds a significant position in production of various number of generic drugs and vaccines. According to Indian Brand Equity Foundation (IBEF) 2017, India accounted for around 20% of global exports in generic drugs and has an immense potential for growth. However, high cost associated with these systems, which make them unaffordable for small emerging players due to limited investment capacity is expected to hinder the market growth.
Market players focused on development of innovative products to maintain leading position in global granulators for pharmaceutical market
The key players are developing novel, innovative, and smart products to maintain leading position in granulators market. For instance, in July 2017, Wittmann introduced a new G-Max 23 granulator, which is a flexible, custom-made granulator that consumes less energy and delivers high performance. Moreover, in 2015, Bosch GmBH developed a new granulation unit Granulean, which is a novel pharmaceutical granulator that collectively carries out the process of mixing, granulating, and drying of the pharmaceutical granules.
Key players operating in the global granulators for pharmaceutical market include Bosch Packaging Technology, Alexanderwerk, GEA Pharma Systems, Frewitt Pharma Machinery, Diosna, Fluid Air, Inc., Romako Pharmatechnik GmbH, and Gebrüder Lödige Maschinenbau GmbH.
Granulators are high speed rotor mills designed to convert a particle powder into sizeable granules. Granulation is a process of binding one or two material together making larger particles by using binding agents such as sugars and natural binders or synthetic polymers. Granulation is performed to improve flow properties of powdered active ingredient, it eases compression during tablet manufacturing. Also, it prevents segregation of the powdered substance. Granulation is performed by two methods, wet granulation and dry granulation. The choice of method depends on characteristics of powder and objective of tablet manufacturing. It refers to the process of size enlargement of pharmaceutical ingredients to prevent segregation of constituents in the powder mix. Granulation is commonly used for production of oral formulation of drugs that usually comprises tablets, pills, and capsules.
Market Dynamics
The granulators for pharmaceutical market is driven by increasing number of new pharmaceutical companies with new manufacturing units, as a result of high demand for medications worldwide. Moreover, the manufacturing unit expansion of existing pharmaceutical giants that invest a significant revenue into R&D for innovative medications is also one of the significant factor driving the market growth. For instance, according to a survey report published by FDA in 2016, the top 15 pharmaceutical companies in the U.S. invested an estimated 20.5% of their pharmaceutical sales back into Research and development to develop and manufacture new drug. Scaling up of pharmaceutical production is thus one of the factors expected to foster growth of the market. However, the high costs of these equipment makes them unaffordable for emerging companies with low capital investments, which is restraining growth of the market.
Key features of the study:
- This report provides in-depth analysis of granulators for pharmaceutical market and provides market size (US$ Million) and Cumulative Annual Growth Rate (CAGR %) for the forecast period (2017 – 2025), considering 2017 as the base year
- It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrix for this market
- This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategy adopted by the leading players
- It profiles leading players in the global granulators for pharmaceutical market based on the following parameters – company overview, financial performance, product portfolio, market presence, distribution strategies, key developments and strategies, and future plans
- Key companies covered as a part of this study includes Bosch Packaging Technology, Alexanderwerk, GEA Pharma Systems, Frewitt Pharma Machinery, Diosna, Fluid Air, Inc., Romako Pharmatechnik GmbH, and Gebrüder Lödige Maschinenbau GmbH
- Insights from this report would allow marketers and the management authorities of the companies to make informed decision regarding their future product launch, technology up-gradation, market expansion, and marketing tactics
- The global granulators for pharmaceutical market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
- Stakeholders would have ease in decision-making through the various strategy matrices used in analyzing the granulators for pharmaceutical market
Detailed Segmentation:
- Global Granulators for Pharmaceutical Market, By Product Type:
- Single Pot Granulators
- High Sheer Granulators
- Fluid Bed Granulators
- Rapid Mixer Granulators
- Oscillating Granulators
- Others
- Global Granulators for Pharmaceutical Market, By Application:
- End Product Manufacturing
- Solid Dosage Formulation
- API Manufacturing
- Others
- Global Granulators for Pharmaceutical Market, By Granulation Mechanism:
- Dry Granulators
- Wet Granulators
- Mixed Granulators
- Global Granulators for Pharmaceutical Market, By End User:
- Pharmaceutical Manufacturing Companies
- Contract Manufacturing Organizations
- Research Institutes
- Others
- Global Granulators for Pharmaceutical Market, By Geography:
- North America
- By Product Type:
- Single Pot Granulators
- High Sheer Granulators
- Fluid Bed Granulators
- Rapid Mixer Granulators
- Oscillating Granulators
- Others
- By Application:
- End Product Manufacturing
- Solid Dosage Formulation
- API Manufacturing
- Others
- By Granulation Mechanism:
- Dry Granulators
- Wet Granulators
- Mixed Granulators
- By End User:
- Pharmaceutical Manufacturing Companies
- Contract Manufacturing Organizations
- Research Institutes
- Others
- By Country:
- U.S.
- Canada
- Latin America
- By Product Type:
- Single Pot Granulators
- High Sheer Granulators
- Fluid Bed Granulators
- Rapid Mixer Granulators
- Oscillating Granulators
- Others
- By Application:
- End Product Manufacturing
- Solid Dosage Formulation
- API Manufacturing
- Others
- By Granulation Mechanism:
- Dry Granulators
- Wet Granulators
- Mixed Granulators
- By End User:
- Pharmaceutical Manufacturing Companies
- Contract Manufacturing Organizations
- Research Institutes
- Others
- By Country:
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- By Product Type:
- Single Pot Granulators
- High Sheer Granulators
- Fluid Bed Granulators
- Rapid Mixer Granulators
- Oscillating Granulators
- Others
- By Application:
- End Product Manufacturing
- Solid Dosage Formulation
- API Manufacturing
- Others
- By Granulation Mechanism:
- Dry Granulators
- Wet Granulators
- Mixed Granulators
- By End User:
- Pharmaceutical Manufacturing Companies
- Contract Manufacturing Organizations
- Research Institutes
- Others
- By Country:
- Germany
- U.K.
- France
- Italy
- Spain
- Russia
- Rest of Europe
- By Product Type:
- Single Pot Granulators
- High Sheer Granulators
- Fluid Bed Granulators
- Rapid Mixer Granulators
- Oscillating Granulators
- Others
- By Application:
- End Product Manufacturing
- Solid Dosage Formulation
- API Manufacturing
- Others
- By Granulation Mechanism:
- Dry Granulators
- Wet Granulators
- Mixed Granulators
- By End User:
- Pharmaceutical Manufacturing Companies
- Contract Manufacturing Organizations
- Research Institutes
- Others
- By Country:
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of Asia Pacific
- Middle East
- By Product Type:
- Single Pot Granulators
- High Sheer Granulators
- Fluid Bed Granulators
- Rapid Mixer Granulators
- Oscillating Granulators
- Others
- By Application:
- End Product Manufacturing
- Solid Dosage Formulation
- API Manufacturing
- Others
- By Granulation Mechanism:
- Dry Granulators
- Wet Granulators
- Mixed Granulators
- By End User:
- Pharmaceutical Manufacturing Companies
- Contract Manufacturing Organizations
- Research Institutes
- Others
- By Country:
- GCC
- Israel
- Rest of Middle East
- Africa
- By Product Type:
- Single Pot Granulators
- High Sheer Granulators
- Fluid Bed Granulators
- Rapid Mixer Granulators
- Oscillating Granulators
- Others
- By Application:
- End Product Manufacturing
- Solid Dosage Formulation
- API Manufacturing
- Others
- By Granulation Mechanism:
- Dry Granulators
- Wet Granulators
- Mixed Granulators
- By End User:
- Pharmaceutical Manufacturing Companies
- Contract Manufacturing Organizations
- Research Institutes
- Others
- By Country:
- South Africa
- Central Africa
- North Africa
- Company Profiles
- Bosch Packaging Technology *
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
- Alexanderwerk
- GEA Pharma Systems
- Frewitt Pharma Machinery
- Fluid Air, Inc.
- Diosna
- Romako Pharmatechnik GmbH
- Gebrüder Lödige Maschinenbau GmbH
“*” marked represents similar segmentation in other categories in the respective section.
Table of Contents
- Research Objective and Assumption
- Research Objectives
- Assumptions
- Abbreviations
- Market Purview
- Report Description
- Market Definition and Scope
- Executive Summary
- Market Snippet, By Product Type
- Market Snippet, By Application
- Market Snippet, By Granulation Mechanism
- Market Snippet, By End User
- Market Snippet, By Region
- Coherent Opportunity Map (COM)
- Market Dynamics, Regulations, and Trends Analysis
- Market Dynamics
- Drivers
- Restraints
- Market Opportunities
- Key Highlights
- Technological Advancements
- Properties of Granulators Available for Pharmaceutical Applications
- Need for Granulators in Pharmaceutical Manufacturing
- Pricing Analysis
- Recent Product Launch
- Global Granulators for Pharmaceutical Market, By Product Type, 2015 – 2025, (US$ Million)
- Introduction
- Market Share Analysis, 2017 and 2025 (%)
- Y-o-Y Growth Analysis, 2016 – 2025
- Segment Trends
- Single Pot Granulators
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- High Sheer Granulators
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Fluid Bed Granulators
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Rapid Mixer Granulators
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Oscillating Granulators
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Others
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Global Granulators for Pharmaceutical Market, By Application, 2015 – 2025, (US$ Million)
- Introduction
- Market Share Analysis, 2017 and 2025 (%)
- Y-o-Y Growth Analysis, 2016 – 2025
- Segment Trends
- End Product Manufacturing
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Solid Dosage Formulation
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- API Manufacturing
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Others
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Global Granulators for Pharmaceutical Market, By Granulation Mechanism, 2015 – 2025, (US$ Million)
- Introduction
- Market Share Analysis, 2017 and 2025 (%)
- Y-o-Y Growth Analysis, 2016 – 2025
- Segment Trends
- Dry Granulators
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Wet Granulators
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Mixed Granulators
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Global Granulators for Pharmaceutical Market, By End User, 2015 – 2025, (US$ Million)
- Introduction
- Market Share Analysis, 2017 and 2025 (%)
- Y-o-Y Growth Analysis, 2016 – 2025
- Segment Trends
- Pharmaceutical Manufacturing Companies
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Contract Manufacturing Organizations (CMO)
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Research Institutes
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Others
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2017 – 2025, (US$ Million)
- Global Granulators for Pharmaceutical Market, By Region, 2017 – 2025, (US$ Million)
- Introduction
- Market Share Analysis, By Region, 2017 and 2025 (%)
- Y-o-Y Growth Analysis, For Region, 2016 – 2025
- North America
- Market Size and Forecast, By Product Type, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Granulation Mechanism, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
- U.S.
- Canada
- Latin America
- Market Size and Forecast, By Product Type, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Granulation Mechanism, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- Europe
- Market Size and Forecast, By Product Type, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Granulation Mechanism, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
- Germany
- U.K.
- France
- Italy
- Spain
- Russia
- Rest of Europe
- Asia Pacific
- Market Size and Forecast, By Product Type, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Granulation Mechanism, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of APAC
- Middle East
- Market Size and Forecast, By Product Type, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Granulation Mechanism, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
- GCC
- Israel
- Rest of Middle East
- Africa
- Market Size and Forecast, By Product Type, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Application, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Granulation Mechanism, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By End User, 2015 – 2025, (US$ Million)
- Market Size and Forecast, By Country, 2015 – 2025, (US$ Million)
- South Africa
- Central Africa
- North Africa
- Competitive Landscape
- Heat Map Analysis
- Market Share Analysis
- Company Profiles
- Bosch Packaging Technology*
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
- Alexanderwerk
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
- GEA Pharma Systems
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
- Frewitt Pharma Machinery
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
- Diosna
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
- Fluid Air, Inc.
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
- Romako Pharmatechnik GmbH
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
- Gebrüder Lödige Maschinenbau GmbH
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
- Section
- Analyst Views
- Section
- References
- Research Methodology
- About us and Sales Contact
*Browse 42 market data tables and 26 figures on "Granulators for Pharmaceutical Market - Global forecast to 2025”.
Research Methodology
Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:
- Primary Research (Trade Surveys and Experts Interviews)
- Desk Research
- Proprietor Data Analytics Model
In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.
Coherent Market Insights desk research is based on a principle set of research techniques:
- National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
- Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.
Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:
- Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
- Trade association, National and international media and trade press.
- Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
- Scientific journals, and other technical magazines and whitepapers.
Preliminary Data Mining
The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.
Data Standardization:
Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.
Coherent Statistical model
We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:
- Micro-economic indicators
- Macro-economic indicators
- Environmental indicators
- Socio-political indicators
- Technology indicators
Data Processing
Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.
Data Validation
This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:
- It provides first-hand information on the market dynamics, outlook, and growth parameters.
- Industry experts validates the estimates which helps the company to cement the on-going research study.
- Primary research includes online surveys, face-to face interviews, and telephonic interviews.
The primary research is conducted with the ecosystem players including, but not limited to:
- Raw Material Suppliers
- Manufacturers
- System Integrators
- Distributors
- End-users
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