Pharmaceutical Granulators Market– Insights
Increasing demand for oral dose medications in the pharmaceutical industry is expected to drive growth of pharmaceutical granulators market. The granulators are used in the process of granulation in which enlargement of particles by agglomeration technique is done. It is one of the most significant operations in the production of pharmaceutical oral solid dosage forms (mostly tablets and capsules). Oral medications have higher preference owing to advantages such as safety of patient, patient compliance, adherence in terms of ease of ingestion, pain avoidance, and versatility in accommodating various types of drugs.
For instance, according to the Nice Insight Pharmaceutical Excipient Survey report of 2017, 65% of the pharmaceutical excipients manufactured are in oral solid dosage. Most pharmaceutical granulators are used for granulation and manufacturing of solid dosage forms. Dry and wet granulation methods are majorly used for tablet and capsules manufacturing. Compaction is also used to densify the powder and form granules.
The global pharmaceutical granulators market is estimated to be valued at US$ 3,435.8 million in 2019, and is expected to exhibit a CAGR of 5.6% over the forecast period (2020-2027).
Global Pharmaceutical Granulators Market Share (%) Analysis, By Product Type, 2019
Source: Coherent Market Insights Analysis (2020)
Global Pharmaceutical Granulators Market- Regional Insights
On the basis of region, the global pharmaceutical granulators market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to be the most lucrative region for growth of the pharmaceutical granulators market owing to presence of pharmaceutical manufacturers in the region with huge production plants that involve mass manufacturing and development of oral pharmaceutical drugs.
Moreover, expansion of production facilities by existing pharmaceutical players and introduction of new production plants by players in the pharmaceutical industry are also contributing to growth of the market in North America. For instance, in March 2017, Apotex, Inc., a Canadian pharmaceutical company, announced an investment of US$ 184 million for expansion of its advanced manufacturing and R&D facility in Florida. Additionally, according to a survey report published by the USFDA in 2016, the top 15 pharmaceutical companies in the U.S. invested an estimated 20.5% of their pharmaceutical sales in research and development of new drugs.
Asia Pacific pharmaceutical granulators market revenue is expected to witness significant growth due to increasing investments by leading pharmaceutical players in expansion of their production units in the region. For instance, in March 2018, Merck KGaA invested US$ 47 million for expansion of manufacturing plants in South Korea and India to develop biologics and other pharmaceutical drugs.
Global Pharmaceutical Granulators Market, Value (US$ Mn) & Y-o-Y Growth (%), 2016-2027
Source: Coherent Market Insights Analysis (2020)
Global Pharmaceutical Granulators Market- Competitive Landscape
Major players operating in the global pharmaceutical granulators market include L.B. Bohle, Alexanderwerk, GEA Group Aktiengesellschaft, Frewitt S.A., LINXIS Group, Spraying Systems Co., Syntegon Technology GmbH, Romaco Group, Gebrüder Lödige Maschinenbau GmbH, and Glatt GmbH.
Granulators are high speed rotor mills designed to convert a particle powder into sizeable granules. Granulation is a process of binding one or two materials together and making larger particles by using binding agents such as sugars and natural binders or synthetic polymers. Granulation is performed to improve flow properties of powdered active ingredients, which, in turn eases compression during tablet manufacturing. Also, it prevents segregation of the powdered substance. Granulation is performed by two methods, wet granulation and dry granulation. The choice of method depends on characteristics of powder and objective of tablet manufacturing. It refers to the process of size enlargement of pharmaceutical ingredients to prevent segregation of constituents in the powder mix. Granulation is commonly used for production of oral drug formulations such as tablets, pills, and capsules.
Furthermore, several pharmaceutical manufacturing companies are exploring technical solutions that can increase quality of drug, process throughput, reduce costs of manufacturing, and increase yield. One of the most promising solutions being studied and implemented is continuous manufacturing (CM). Continuous granulation is performed to continuously manufacture APIs and excipients. The process of continuous manufacturing is gaining momentum in the pharmaceutical industry owing to increasing demand for faster product development, reduced costs of manufacturing, and higher manufacturing flexibility. The integration of continuous manufacturing process in the pharmaceuticals manufacturing industry has significantly increased efficiency of API and excipient manufacturers.
The pharmaceutical companies are focusing on expansion of their production facilities which would create additional demand for granulators used for producing drugs and for R&D activities. The increasing investments in production facilities by key players attributed to the growth of global pharmaceutical granulators market. For instance in September 2017, Fresenius Kabi announced an investment of US$ 250 million to establish a pharmaceutical plant in Illinois, U.S. for aseptic manufacturing of pharmaceutical drugs. Similarly, according to a survey report published by the USFDA in 2016, the top 15 pharmaceutical companies in the U.S. invested around 20.5% of their pharmaceutical sales in research and development of new drugs. Such strategies adopted by key players is projected to drive demand for pharmaceutical granulators.
Furthermore, technological innovations in development of drugs is another factor driving the growth of this market. For instance, in July 2017, Wittmann Battenfeld, Inc. introduced a new G-Max 23 granulator, which is a flexible, custom-made granulator that consumes less energy and delivers high performance. Additionally, in 2015, the Bosch GmBH, a Germany-based company developed a new granulation unit, Granulean, which is a novel pharmaceutical granulator that collectively carries out the process of mixing, granulating, and drying of the pharmaceutical granules. The launch of innovative and technologically advanced products is expected to drive growth of this market during the forecast period.
Key features of the study:
“*” marked represents similar segmentation in other categories in the respective section.