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Immune Health Supplements Market Analysis & Forecast: 2025-2032

Immune Health Supplements Market, By Ingredients (Vitamins, Omega-3 Fatty Acids, Probiotics, Minerals, and Others), By Source (Plant-based, and Animal-based), By Form (Tablets, Capsules, Powder, and Liquid), By Distribution Channel (Supermarkets, Retail Pharmacies, and Online Pharmacies), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa)

  • Published In : Jun 2025
  • Code : CMI4065
  • Pages :216
  • Formats :
      Excel and PDF
  • Industry : Pharmaceutical

Immune Health Supplements Market Analysis & Forecast

Immune Health Supplements Market size is estimated to be valued at USD 21.8 Bn in 2025 and is expected to reach USD 35.93 Bn in 2032, exhibiting a compound annual growth rate (CAGR) of 7.4% from 2025 to 2032.

Key Takeaways

  • By Ingredient, the Vitamins segment is projected to dominate the global immune health supplement market during the forecast period, capturing approximately 35% of the market share due to their widespread use and recognized benefits in supporting immune function.
  • By Region, North America is expected to hold the largest share at an estimated 45.1% in 2025, driven by high consumer awareness, strong healthcare infrastructure, and growing demand for preventive health products.

Market Overview

Global Immune Health Supplement Market growth is driven by the rise in demand for immune boosters as a result of the rising prevalence of chronic diseases and other disorders among the senior population. Since new launches and partnerships are likely to fuel market expansion during the forecast period, major players in the global immune health supplement market are concentrating on these strategies.

For instance, on April 17, 2023, MiAlgae, a microalgal production company, launched its latest product, NaturAlgae, an omega-3 powder that can be used as a nutritious feed ingredient. NaturAlgae, is a dry powder with a high concentration of DHA (Docosahexaenoic acid) and other oils that can be added to recipes for aqua feeds, providing the well-known health benefits that omega-3 provides. With its innovative manufacturing process, the company aims to reduce global reliance on wild-caught fish, the traditional source of omega-3 products.

Current Events and Its Impact on the Global Immune Health Supplement Market

Event

Description and Impact

Regulatory Evolution in Key Markets

  • Description: FDA tightens compliance requirements for dietary ingredients. For instance, in June 2025, the FDA introduced stricter NDIN (New Dietary Ingredient Notification) requirements, delaying several U.S. product launches and increasing the burden on R&D teams.
  • Impact: Raises R&D costs by 15–20%, disadvantaging small and medium enterprises (SMEs) while favoring larger supplement manufacturers.
  • Description: EU expands its list of authorized novel food ingredients. For example, in 2025, the European Commission approved five new substances including monosodium folate for use in immune supplements.
  • Impact: Offers broader formulation opportunities but lengthens the regulatory approval timeline, delaying EU market entry.

Macroeconomic Pressures

  • Description: F lowers global economic growth forecast. For example, the 2025 downgrade to 2.8% reflects slower consumer spending in top markets such as the U.S. and China.
  • Impact: Weakens demand for premium immune supplements, shifting sales momentum toward lower-cost, economy-tier products.
  • Description: Inflation persists at elevated levels. For instance, the 2024 average global inflation rate was 5.9%, driving up costs across manufacturing and logistics.
  • Impact: Compresses profit margins, prompting 8–12% price increases for popular categories like immune gummies and probiotics.

Technological & Consumer Shifts

  • Description: Surge in AI-driven personalized nutrition. For instance, platforms leveraging genomics and microbiome data are growing at a CAGR of 16.6%, offering consumers tailored immune support.
  • Impact: Captures 35% of high-income consumers by 2030, reshaping demand toward individualized supplement solutions.
  • Description: E-commerce accelerates immune supplement access in emerging markets. For example, online sales channels—growing at a 13% CAGR—are fueling direct-to-consumer adoption in countries like India and the UAE.
  • Impact: Drives 20% sales growth in underserved markets, reducing dependency on traditional retail infrastructure.

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Pipeline Analysis: Immune Health Supplements Market

There are numerous innovative compounds moving through clinical trials that could be used in immune health supplements. Wellmune WGP, a beta-glucan made by the Kerry Group, and Talactoferrin alfa (lactoferrin by Agennix) are undergoing Phase III trials where their immune modulation features such as macrophage activation and iron-regulated immune responses are being evaluated. Epicor (yeast fermentate), ImmunEnhancer AG (rice bran arabinoxylan), and Wellmune are also in Phase II with Epicor targeting respiratory functions alongside the late-stage Innate Immune System competitors.

A probiotic LGG + BB-12 is in mid-stage trials for gut microbiome modulation targeted at microbials for respiratory infection prevention. In phase I of testing, early stage research on Fucoidan Extract, Quercetin Phytosome, Transfer Factor E-XF , and the bovine lactoferrin Immulox is centered around safety-testing bioavailability and immunomodulatory efficacy.

Preclinical work has begun on TA-65 Astragalus, elderberry extract, and the AHCC mushroom complex which have demonstrated activities supporting the enhancement of immunity. At this time however there is no available data suggesting they have undergone any form of clinical level tests.

Meanwhile postbiotic metabolites of postbiotics offer new insight into technology suggesting next-generation control methods for immunity by directly communicating with cells to regulate them. This rich pipeline showcases ongoing functional investment from various suppliers focusing on delivery systems designed specifically around targeted immune formulations.

Patent Landscape: Immune Health Supplements Market

In the immune health supplements market, innovation is on the rise, with patent filings steadily increasing over new ingredients, formulations, and delivery methods. Leading firms are securing patents on bioactive ingredients like beta-glucans, probiotics, lactoferrin, elderberry and astragalus botanicals. Patents are increasingly concerning combination ingredients that synergistically and holistically improve the immune response as well as bioavailability.

There is a noticeable increase in patent activity dealing with advanced absorption technologies such as liposomal encapsulation, phytosome technology, and nano-encapsulation aimed at improving absorption and effectiveness. Targeted demographic specific immune support (e.g. elderly or children) and condition specific formulations (e.g. for respiratory health or stress induced immune suppression) are also being patented. Kerry Group, Glanbia Nutritionals, Indena S.p.A., and some biotech start-ups working with universities hold patents along with other postbiotics-focused endobiotic systems modifying modulators of the immune system formulation developers indicating next-gen solutions in evolution.

It still appears there is a lot of room for further innovation around immunity functional health supplements post-covid era given all active patents as expressed in greater detail above show only few companies holding dominating positions for developing cutting-edge supplements losing the race for carving out proprietary disregarded formulations strengthening that gap between diverse but stagnant fast-changing growing markets.

In the immune health supplements market, innovation is on the rise, with patent filings steadily increasing over new ingredients, formulations, and delivery methods. Leading firms are securing patents on bioactive ingredients like beta-glucans, probiotics, lactoferrin, elderberry and astragalus botanicals. Patents are increasingly concerning combination ingredients that synergistically and holistically improve the immune response as well as bioavailability.

There is a noticeable increase in patent activity dealing with advanced absorption technologies such as liposomal encapsulation, phytosome technology, and nano-encapsulation aimed at improving absorption and effectiveness. Targeted demographic specific immune support (e.g. elderly or children) and condition specific formulations (e.g. for respiratory health or stress induced immune suppression) are also being patented. Kerry Group, Glanbia Nutritionals, Indena S.p.A., and some biotech start-ups working with universities hold patents along with other postbiotics-focused endobiotic systems modifying modulators of the immune system formulation developers indicating next-gen solutions in evolution.

It still appears there is a lot of room for further innovation around immunity functional health supplements post-covid era given all active patents as expressed in greater detail above show only few companies holding dominating positions for developing cutting-edge supplements losing the race for carving out proprietary disregarded formulations strengthening that gap between diverse but stagnant fast-changing growing markets.

Reimbursement Scenario: Immune Health Supplements Market

The worldwide landscape for reimbursement in immune health supplements remains quite restricted and fragmented because they are classified as dietary supplements, not essential medicine. There is secondary public/private coverage but only on a regional basis. For example, in the US Medicare Parts A and B granted coverage on immune supplements to not include these Medicare benefits.

Some Medicare Advantage plans can offer limited wellness allowances up to 8 USD per beneficiaries annually. Private insurers like Aetna and Anthem provide 10-30% reimbursement under wellness or health saving plans, with annual reimbursed totals ranging from 127-300 USD. Across EU, other low reimbursement rate contributing policies such as Regulation (EC) No 1924/2006 are claiming restrictions which are assessing their rebates at 2-8%. National limits like NHS England or HAS evaluate on his/her own for case basis review claim restriction evaluation.

On the Asia Pacific side Japan and Australia apply FOSHU and TGA listed medicines oversight on immunesupplemenst regulation but do limit reimbursement mostly to physician recommended use for defined criteria deficiency products only. On average less than five percent of immune health supplements get insured worldwide reimbursements granted access through these guidelines set forth globally. However gradual enhancements presuming integration into wellness programs along with growing clinical evidence issued along increasing demand for preventive care might stand improved prospects reliability in the near future.

Prescribers’ Preference: Immune Health Supplements Market

Prescribers including physicians, nurse practitioners, and clinical pharmacists are increasingly integrating immune health supplements into preventive and adjunctive care strategies. Their preferences are shaped by patient demographics, clinical evidence, comorbidities, and supplement safety profiles.

For primary prevention, general practitioners favor evidence-backed, single-ingredient supplements like vitamin D3, vitamin C, zinc, and probiotics, particularly for maintaining immune function in healthy individuals. The widespread deficiency of vitamin D and its immunomodulatory role drives strong prescriber support.

In secondary prevention, targeted at at-risk populations such as older adults, immunocompromised individuals, and healthcare workers, prescribers prefer adaptogenic and immune-modulating botanicals like elderberry, echinacea, astragalus, and beta-glucans, especially among geriatricians and integrative medicine specialists.

For disease-specific interventions, ENT specialists and pulmonologists recommend N-acetylcysteine (NAC), Pelargonium sidoides, and vitamin C + zinc for recurrent respiratory tract infections. Pediatricians tend to opt for gentler options such as elderberry syrup, while functional medicine practitioners may include quercetin, lactoferrin, or advanced immune complexes in adjunctive care, especially for chronic or autoimmune conditions.

Overall, prescribers show strong preference for clinically validated formulations with high bioavailability, minimal drug interactions, and demonstrated cost-effectiveness.

Segmental Insights

Immune Health Supplements Market By Ingredient

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Global Immune Health Supplement Market Insights, By Ingredient

The ingredient segment is categorized into vitamins, omega-3 fatty acids, probiotics, minerals, and others. The vitamins segment is expected to dominate the market with 35.0% share during the forecast period, driven primarily by the increasing prevalence of chronic diseases and related disorders among the geriatric population. Vitamins play a crucial role in supporting immune function, making them a preferred choice for older adults managing multiple health conditions.

Global Immune Health Supplement Market Insights, By Source

The source segment is divided into plant-based and animal-based supplements. The plant-based segment is projected to hold the largest share over the forecast period, owing to rising consumer demand for vegetarian and vegan options. Most vitamins originate from plant sources, aligning with the increasing preference for natural and sustainable supplements.

Global Immune Health Supplement Market Insights, By Form

The form segment includes tablets, capsules, powders, and liquids. Tablets are anticipated to dominate the market throughout the forecast period due to their ease of use, dosage accuracy, and consumer familiarity. Growing health awareness and the need to boost immunity, especially during and after the pandemic, continue to support strong tablet sales.

Global Immune Health Supplement Market Insights, By Distribution Channel

The distribution channel segment comprises supermarkets, retail pharmacies, and online pharmacies. Online pharmacies are expected to lead the market, driven by factors such as wider accessibility, lower transaction and product costs, convenience, and consumer preference for discreet purchases.

Global Immune Health Supplement Market – Regional Insights

Immune Health Supplements Market Regional Insights

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North America Immune Health Supplement Market Analysis and Trends

North America is projected to hold a dominant position in the global immune health supplement market with an estimated 45.10% share in 2025, driven by continuous product innovations and launches from key market players. For example, in October 2025, Epax, a marine ingredient innovator, introduced a novel product featuring cetoleic acid—a unique omega-11 polyunsaturated fatty acid distinct from traditional omega-3s.

Found in fish species such as saury, pollock, and herring, cetoleic acid, branded as Cetoleic 10, represents a breakthrough ingredient expanding the nutritional scope of immune supplements. The region’s strong R&D capabilities, coupled with rising consumer focus on preventive health and advanced nutraceuticals, reinforce North America’s leadership in this sector.

Asia Pacific Immune Health Supplement Market Analysis and Trends

Asia Pacific is rapidly emerging as a key growth region for immune health supplements, propelled by increasing health awareness, expanding middle-class populations, and improving healthcare infrastructure in countries such as China and India. Government initiatives promoting preventive healthcare and rising adoption of dietary supplements contribute to accelerated market expansion.

Leading global manufacturers are establishing local operations and partnerships to cater to the region’s diverse consumer base. Despite regulatory challenges and variable market maturity, Asia Pacific’s large population and evolving lifestyle patterns position it as a vital market for future growth.

Dominating Countries in the Immune Health Supplement Market

United States Immune Health Supplement Market Analysis and Trends

The United States leads the global immune health supplement market, supported by a mature nutraceutical industry, high consumer health consciousness, and strong innovation pipelines. U.S.-based companies frequently launch novel ingredients and formulations, benefiting from supportive regulatory frameworks and wide distribution channels. High demand for immune-boosting supplements, especially post-pandemic, has further accelerated market growth.

China Immune Health Supplement Market Analysis and Trends

China plays a pivotal role in Asia Pacific’s immune health supplement market growth. Rising health awareness, increased disposable income, and government efforts to promote wellness products are driving demand. The expansion of e-commerce platforms and domestic manufacturing capabilities further support China’s position as both a major consumer and producer in the immune supplement segment.

Market Report Scope

Immune Health Supplements Market Report Coverage

Report Coverage Details
Base Year: 2024 Market Size in 2025: USD 21.8 Bn
Historical Data for: 2020 To 2024 Forecast Period: 2025 To 2032
Forecast Period 2025 to 2032 CAGR: 7.4% 2032 Value Projection: USD 35.93 Bn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Ingredients: Vitamins, Omega 3 Fatty Acids, Probiotics, Minerals, Others
  • By Source: Plant-based, Animal-based
  • By Form: Tablets, Capsule, Powder, Liquid
  • By Distribution Channel: Supermarkets, Retail Pharmacies, Online Pharmacies
Companies covered:

Abbott, Bayer AG, Glanbia PLC, EuroPharma USA, Bio-Tech Pharmacal, Vital Nutrients, Herbalife International of America, Inc., Vitabiotics Ltd., NutriGold Inc., BioGaia, NIC (Natural Immunogenics Corporation), Blackmores, Wellbeing Nutrition, NutriScience Innovations LLC, DSM Nutritional Products AG, and Nutramax Laboratories Veterinary Sciences, Inc.

Growth Drivers:
  • Product launch of immune health supplement by key players 
  • Government initiatives and funding for immune health supplement research
Restraints & Challenges:
  • Lack of consumer awareness about immune health supplements

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Global Immune Health Supplement Market– Drivers

  • Product launch of immune health supplement

Product launch of immune health supplements by the market key players to enhance their product portfolio is expected to the growth of the global immune health supplement market over the forecast period.

For instance, in February 2022, Unigen, a manufacturer of drug substances for bio-pharmaceuticals, introduced two new botanical ingredients at the Natural Products Expo West in the U.S. The new ingredients in Unigen’s botanical suite are Attenutin for respiratory health and Symetrian for immune homeostasis. Unigen also tested many immune regulatory polysaccharides in combinations with different polyphenols that led to successful clinical trials of an Aloe polysaccharide-based composition called Symetrian.

  • Government initiatives and funding for immune health supplement research

Increasing government initiatives and funding for immune health supplement research is expected to drive the market growth over the forecast period. For instance, on February 2023, the Government of Canada announced an investment of US$ 198.6 billion over 10 years, including US$ 46.2 billion in new funding, to improve health care services for Canadians. This funding includes an immediate, unconditional US$ 2 billion Canada Health Transfer (CHT) top-up to address immediate pressures on the healthcare system.

Global Immune Health Supplement Market- Cross Sectional Analysis

Among ingredients, the vitamin segment held a dominant position in North America region over the forecast period due to the increasing number of chronic diseases and disorders in the geriatric population. For instance, in January 2021, according to the Centers for Medicare & Medicaid Services, in 2020, approximately 43%, or 133 million, people in the U.S. have one or more chronic illnesses. Based on data from the International Journal of Environmental Research and Public Health (IJEPH), in June 2020, approximately 25% of adults in the US have two or more chronic conditions.

Global Immune Health Supplement Market- Key Trends

  • Partnership by the key players

Partnership by the key market players to increase the product portfolio is expected to fuel the market over the forecast period. For instance, on May 09, 2023, Roquette Frères, a global company specialist in plant-based ingredients and a provider of pharmaceutical and nutraceutical excipients, announced the launch of its new excipient– PEARLITOL ProTec.

A unique, plant-based co-processed blend of mannitol and maize starch, this solution protects and stabilizes moisture-sensitive active ingredients like probiotics, unlocking longer shelf life, improved consistency, and wider opportunities for consumer-friendly dosage formats.

Analyst Viewpoint

  • The immune health supplements market is experiencing strong growth fueled by heightened consumer focus on preventive wellness, a trend accelerated by the global pandemic. An aging global population increasingly prioritizes proactive immune support, while rising healthcare expenses encourage investment in supplementation as a cost-effective preventive measure.
  • Scientific validation of immune-enhancing ingredients such as vitamin D, zinc, elderberry, and probiotics is bolstering consumer confidence and education around micronutrient deficiencies. Additionally, the rapid expansion of e-commerce platforms has enhanced product accessibility, allowing brands to engage diverse consumer segments through targeted digital marketing.
  • Despite these growth drivers, the market faces challenges from stringent regulatory requirements that limit health claims and lengthen product approval timelines, especially in mature markets. Economic uncertainty also influences consumer price sensitivity, complicating premium product positioning.
  • Significant opportunities lie in personalized nutrition, where consumers demand immune supplements tailored to their unique health profiles and lifestyles. Innovations in product formats—such as gummies, powders, and functional beverages—are broadening consumer appeal beyond traditional pills.
  • Regionally, North America leads the market with its high disposable income and established supplement culture, while Asia-Pacific is the fastest-growing region. Growth in Asia-Pacific is propelled by expanding middle-class populations, increasing health awareness, improved distribution networks, and the cultural acceptance of traditional medicine in countries like China and India, facilitating supplement adoption.

Global Immune Health Supplement Market- Key Developments

  • On January 23, 2023, Jarrow Formulas, a formulator and supplier of nutritional supplements, announced the launch of Fem-Dophilus Advanced, their newest targeted probiotic product which supports vaginal, urinary tract, digestive and immune health in just one veggie capsule per day.
  • On March 23, 2023, ChildLife Essentials, a children's nutrition company, announced the launch of its new Organic Liquid Elderberry supplement. This powerful formula is specifically designed to support kids’ immune health and promote overall wellness.
  • On February 09, 2023, GC Rieber VivoMega, a producer of marine-derived high Omega3 concentrates, launched VivoMega Algae Oils, its ocean-derived, high-concentration vegan Omega-3 from microalgae.

Market Segmentation

  • Global Immune Health Supplement Market, By Ingredients
    • Vitamins
    • Omega 3 Fatty Acids
    • Probiotics
    • Minerals
    • Others
  • Global Immune Health Supplement Market, By Source
    • Plant-based
    • Animal-based
  • Global Immune Health Supplement Market, By Form
    • Tablets
    • Capsule
    • Powder
    • Liquid
  • Global Immune Health Supplement Market, By Distribution Channel
    • Supermarkets
    • Retail Pharmacies
    • Online Pharmacies
  • Global Immune Health Supplement Market, By Region
    • North America
      • U.S.
      • Canada
    • Latin America
      • Brazil
      • Mexico
      • Argentina
      • Rest of Latin America
    • Europe
      • Germany
      • U.K.
      • France
      • Italy
      • Spain
      • Russia
      • Rest of Europe
    • Asia Pacific
      • China
      • India
      • Japan
      • Australia
      • South Korea
      • ASEAN
      • Rest of Asia Pacific
    • Middle East
      • GCC
      • Israel
      • Rest of Middle East
    • Africa
      • South Africa
      • Central Africa
      • North Africa
  • Company Profiles
    • Abbott
    • Bayer AG
    • Glanbia PLC
    • EuroPharma USA
    • Bio-Tech Pharmacal
    • Vital Nutrients
    • Herbalife International of America, Inc.
    • Vitabiotics Ltd
    • NutriGold Inc.
    • BioGaia
    • NIC (Natural Immunogenics Corporation)
    • Blackmores
    • Wellbeing Nutrition
    • NutriScience Innovations LLC
    • DSM Nutritional Products AG
    • Nutramax Laboratories Veterinary Sciences, Inc.

Sources

Primary Research Interviews

  • Immune health supplement manufacturers and brand executives
  • E-commerce platform representatives and online retailers
  • Healthcare professionals and nutritionists
  • Consumers and end-users of immune health supplements
  • Others

Databases

  • Others

Magazines

  • Natural Products Insider
  • Nutraceuticals World
  • Nutritional Outlook
  • Vitamin Retailer Magazine
  • Others

Journals

  • Journal of Nutritional Biochemistry
  • Nutrients Journal
  • Journal of Dietary Supplements
  • Others

Newspapers

  • The Wall Street Journal
  • Financial Times
  • Reuters Health News
  • Bloomberg Healthcare
  • Others

Associations

  • Council for Responsible Nutrition (CRN)
  • Natural Products Association (NPA)
  • International Alliance of Dietary/Food Supplement Associations (IADSA)
  • American Herbal Products Association (AHPA)
  • Others

Public Domain Sources

  • U.S. Food and Drug Administration (FDA) publications
  • World Health Organization (WHO) reports
  • National Institutes of Health (NIH) databases
  • European Food Safety Authority (EFSA) guidelines
  • Others

Proprietary Elements

  • CMI Data Analytics Tool
  • Proprietary CMI Existing Repository of information for last 8 years

*Definition: Immune health supplements are important for the management of certain chronic conditions such as diabetes, obesity, constipation, malabsorption, and indigestion. It also helps to maintain a healthy lifestyle, improve appetite and food intake, and lower the risk of nutrient deficiencies, and other health conditions. Immune health supplements are recommended for patients of all ages including infants, adults, and geriatrics, who are susceptible to conditions such as diabetes, obesity, renal failures, chronic diseases, neurological diseases, and others. These factors have led to an increase in demand for immune health supplements.

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About Author

Ghanshyam Shrivastava - With over 20 years of experience in the management consulting and research, Ghanshyam Shrivastava serves as a Principal Consultant, bringing extensive expertise in biologics and biosimilars. His primary expertise lies in areas such as market entry and expansion strategy, competitive intelligence, and strategic transformation across diversified portfolio of various drugs used for different therapeutic category and APIs. He excels at identifying key challenges faced by clients and providing robust solutions to enhance their strategic decision-making capabilities. His comprehensive understanding of the market ensures valuable contributions to research reports and business decisions.

Ghanshyam is a sought-after speaker at industry conferences and contributes to various publications on pharma industry.

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Frequently Asked Questions

The Immune Health Supplements Market size is estimated to be valued at USD 21.8 Bn in 2025, and is expected to reach USD 35.93 Bn by 2032.

The CAGR of the global Market is projected to be 7.4% from 2025 to 2032.

Product launch of immune health supplement by the key players and government initiatives and funding for immune health supplement research is expected to drive the market growth.

Vitamins is the leading segment in the market.

Lack of consumer awareness about immune health supplements is expected to hamper the market growth.

Major players operating in the market include Abbott, Bayer AG, Glanbia PLC, EuroPharma USA, Bio-Tech Pharmacal, Vital Nutrients, Herbalife International of America, Inc., Vitabiotics Ltd., NutriGold Inc., BioGaia, NIC (Natural Immunogenics Corporation), Blackmores, Wellbeing Nutrition, NutriScience Innovations LLC, DSM Nutritional Products AG and Nutramax Laboratories Veterinary Sciences, Inc.
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