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  • Published On : Nov 2021
  • Code : CMI4795
  • Industry : Pharmaceutical
  • Pages : 142
  • Formats :

Immunohistochemistry (IHC) is a technique that combines anatomical, immunological, and biochemical methods to visualize discrete components in tissues using suitably labelled antibodies that bind to their target antigens in situ. IHC allows researchers to visualize and describe the high-resolution distribution and localization of certain cellular components within cells and their histological background. While IHC methodology has various approaches and permutations, all of the processes are divided into two categories: sample preparation and sample staining. IHC is used for disease diagnosis, biological research, and in drug testing.

The global immunohistochemistry (IHC) market is estimated to be valued at US$ 2,020.2 Million in 2021 and is expected to increase to US$ 3,348.7 Million by 2028, witnessing a CAGR of 7.5% over the forecast period (2021-2028).

Figure 1. Global Immunohistochemistry (IHC) Market Share (%), By Region, 2021

Immunohistochemistry  | Coherent Market Insights

The rising geriatric population is expected to drive the growth of the global immunohistochemistry (IHC) market.

The growing elderly population in both developed (such as UK, Canada, and others) and developing countries (such as India, Brazil, China, and others) will boost the growth of the global immunohistochemistry (IHC) market. The prevalence of age-related disorders is predicted to rise significantly as the global geriatric population grows rapidly. For instance, according to the Organisation for Economic Co-operation and Development (OECD), there were 54 million elderly individuals in the U.S. in 2019. Geriatric populations are likewise significant and expanding in other developed economies around the world. The risk of acquiring diseases increases in direct proportion to a person’s age. As a result, the global prevalence of numerous diseases such as cancer, cardiovascular diseases, and others is predicted to rise as the elderly population grows.

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Immunohistochemistry (IHC) Market Report Coverage

Report Coverage Details
Base Year: 2020 Market Size in 2021: US$ 2,020.2 Mn
Historical Data for: 2017 to 2020 Forecast Period: 2021 to 2028
Forecast Period 2021 to 2028 CAGR: 7.5% 2028 Value Projection: US$ 3,348.7 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Product: Antibodies (Primary Antibodies, Secondary Antibodies), Equipment (Slide Staining Systems, Tissue Microarrays, Tissue Processing Systems, Slide Scanners, Others), Reagents (Histological Stains, Blocking Sera and Reagents, Chromogenic Substrates, Fixation Reagents, Stabilizers, Others), Kits
  • By Application: Diagnostics (Cancer, Infectious Diseases, Cardiovascular Diseases, Autoimmune Diseases, Diabetes Mellitus, Others), Drug Testing, Forensic Applications
  • By End User: Hospitals, Diagnostic Laboratories, Research Institutes, Others
Companies covered:

Thermo Fisher Scientific, Inc., F. Hoffmann-La Roche Ltd., Merck KGaA, Danaher Corporation, Perkinelmer, Inc., Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Bio SB, Agilent Technologies, Inc., Abcam plc., Becton, Dickinson and Company, Takara Bio, Inc.,  Eagle Biosciences, Inc., Biocare Medical, LLC, Biogenex Laboratories, Diagnostic Biosystems, Inc., and BioVision Inc.

Growth Drivers:
  • Increasing  prevalence of chronic diseases such as cancers, cardiovascular diseases, and others
  • Increasing global geriatric population
  • Increasing product launches
Restraints & Challenges:
  • Lack of specificity associated with IHC technology
  • High cost of setup

Figure 2. Global Immunohistochemistry (IHC) Market Share (%), By Product, 2021

Immunohistochemistry  | Coherent Market Insights

Global Immunohistochemistry (IHC) Market – Regional Insights

North America is expected to dominate the global immunohistochemistry (IHC) market during the forecast period, owing to a well-developed healthcare infrastructure. Moreover, IHC instruments are increasingly being used in laboratories and diagnostic facilities. The favorable reimbursement structure in this region is further encouraging the market penetration of automated immunohistochemistry devices. The incidence of cancer is also on the rise in this region, which is fueling demand for IHC procedures and resulting in profitable market expansion. For instance, according to National Institutes of Health (NIH) statistics, in 2020, around 1,806,590 new cases of cancer were diagnosed in the United States and 606,520 people died from the disease.

Due to strong economic expansion in nations such as China, India, South Korea, and Singapore, the Asia Pacific region is predicted to grow the fastest. Several factors are contributing to this trend, including increased disposable income, rising healthcare spending, expanding demand for high-quality medical treatment, and rising pharmaceutical and biotech company investments. Other important reasons supporting the growth of the immunohistochemistry (IHC) market in APAC are the rising prevalence of chronic diseases, the fast growing geriatric population, growing academic and government spending in diagnostic research, and the existence of numerous industry participants.

Global Immunohistochemistry (IHC) Market – Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe. The coronavirus (COVID-19) pandemic and lockdown in various countries across the globe has impacted the financial status of businesses in all sectors. Private healthcare sector is one of the sectors, which is majorly impacted by the COVID-19 pandemic.

Detection of SARS-CoV-2 using IHC technique, on the other hand, is critical for characterizing disease progression. Thus, impact of the coronavirus (COVID-19) pandemic is expected to drive the growth of the global immunohistochemistry (IHC) market over the forecast period. For instance, according to an article published in Laboratory Investigation journal in July 2020, immunohistochemical (IHC) and in situ hybridization (ISH) assays for detection of the SARS-CoV-2 was developed and eight samples from COVID-19 patients were stained. It was found that all eight samples were stained positive by IHC and ISH whereas all specimens from non-COVID-19 patients were IHC and ISH negative.

Global Immunohistochemistry (IHC) Market: Restraint

The lack of specificity associated with IHC technology and the high cost of setup are expected to hamper the global immunohistochemistry (IHC) market. Accurate and early diagnosis of cancer growth is very important in the treatment of any disease. However, IHC technology can be difficult to accept due to its lack of specificity in diagnosing some of the chronic diseases. The high setup costs of IHC devices place a heavy burden on hospitals and diagnostic laboratories in developing countries like China, India and others and limit the growth of the global immunohistochemistry (IHC) market.

Key Players

Major players operating in the global immunohistochemistry (IHC) market include Thermo Fisher Scientific, Inc., F. Hoffmann-La Roche Ltd., Merck KGaA, Danaher Corporation, Perkinelmer, Inc., Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Bio SB, Agilent Technologies, Inc., Abcam plc. , Becton, Dickinson and Company, Takara Bio, Inc., Biosciences, Inc., Biocare Medical, LLC, Biogenex Laboratories, Diagnostic Biosystems, Inc., and BioVision Inc.

Immunohistochemistry (IHC) is an experimental method that uses antibodies to locate specific antigens (markers) in tissue samples. Antibodies usually bind to enzymes or fluorescent dye. After the antibody binds to the antigen in the tissue sample, the enzyme or dye is activated and then the antigen can be observed under a microscope. Immunohistochemistry is useful in diagnosing diseases such as cancer, infectious diseases, and cardiovascular diseases (CVDs), and others. It can also be used to distinguish between different types of cancer.

IHC as a crucial application of monoclonal and polyclonal antibodies, helps understand tissue distribution of an antigen. It is used in the identification of enzymes, tumor suppressor genes, antigens, and tumor cell proliferation. IHC involves specific antigen-antibody reactions compared to traditional enzyme staining techniques that identify a limited number of proteins, enzymes, and tissue structures. As a result, visualizing the distribution and location of specific cellular components within cells is becoming increasingly important as an important technique in medical laboratories and clinical diagnostics.

Market Dynamics

Increasing prevalence of chronic diseases such as cancer is anticipated to drive the growth of global immunohistochemistry (IHC) market over the forecast period. For instance, according to the National Institutes of Health (NIH), in 2018, an estimated 1,735,350 new cases of cancer were detected in the U.S. Moreover, according to data published by World Health Organization (WHO) in 2018, globally, cancer was one of the leading causes of mortality, and in 2018 approximately 9.6 million deaths were registered globally due to cancer.

Key features of the study:

  • This report provides in-depth analysis of the global immunohistochemistry (IHC) market, and provides market size (US$ Million) and compound annual growth rate (CAGR %) for the forecast period (2021-2028), considering 2020 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the global immunohistochemistry (IHC) market based on the following parameters – company highlights, Products portfolio, key highlights, financial performance, and market strategies
  • Key companies covered as a part of this study include Thermo Fisher Scientific, Inc., F. Hoffmann-La Roche Ltd., Merck KGaA, Danaher Corporation, Perkinelmer, Inc., Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Bio SB, Agilent Technologies, Inc., Abcam plc., Becton, Dickinson and Company, Takara Bio, Inc., Eagle Biosciences, Inc., Biocare Medical, LLC, Biogenex Laboratories, Diagnostic Biosystems, Inc., and BioVision Inc.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, Product up-gradation, market expansion, and marketing tactics
  • The global immunohistochemistry (IHC) market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global immunohistochemistry (IHC) market

Detailed Segmentation:

  • Global Immunohistochemistry (IHC) Market, By Product:
    • Antibodies
      • Primary Antibodies
      • Secondary Antibodies
    • Equipment
      • Slide Staining Systems
      • Tissue Microarrays
      • Tissue Processing Systems
      • Slide Scanners
      • Others
    • Reagents
      • Histological Stains
      • Blocking Sera and Reagents
      • Chromogenic Substrates
      • Fixation Reagents
      • Stabilizers
      • Others
    • Kits
  • Global Immunohistochemistry (IHC) Market, By Application:
    • Diagnostics
      • Cancer
      • Infectious Diseases
      • Cardiovascular Diseases
      • Autoimmune Diseases
      • Diabetes Mellitus
      • Others
    • Drug Testing
    • Forensic Applications
  • Global Immunohistochemistry (IHC) Market, By End User:
    • Hospitals
    • Diagnostic Laboratories
    • Research Institutes
    • Others
  • Global Immunohistochemistry (IHC) Market, By Region:     
    • North America
      • By Product
        • Antibodies
          • Primary Antibodies
          • Secondary Antibodies
        • Equipment
          • Slide Staining Systems
          • Tissue Microarrays
          • Tissue Processing Systems
          • Slide Scanners
          • Others
        • Reagents
          • Histological Stains
          • Blocking Sera and Reagents
          • Chromogenic Substrates
          • Fixation Reagents
          • Stabilizers
          • Others
        • Kits
      • By Application
        • Diagnostics
          • Cancer
          • Infectious Diseases
          • Cardiovascular Diseases
          • Autoimmune Diseases
          • Diabetes Mellitus
          • Others
        • Drug Testing
        • Forensic Applications
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Research Institutes
        • Others
      • By Country
        • U.S.
        • Canada
    • Latin America
      • By Product
        • Antibodies
          • Primary Antibodies
          • Secondary Antibodies
        • Equipment
          • Slide Staining Systems
          • Tissue Microarrays
          • Tissue Processing Systems
          • Slide Scanners
          • Others
        • Reagents
          • Histological Stains
          • Blocking Sera and Reagents
          • Chromogenic Substrates
          • Fixation Reagents
          • Stabilizers
          • Others
        • Kits
      • By Application
        • Diagnostics
          • Cancer
          • Infectious Diseases
          • Cardiovascular Diseases
          • Autoimmune Diseases
          • Diabetes Mellitus
          • Others
        • Drug Testing
        • Forensic Applications
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Research Institutes
        • Others
      • By Country
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Product
        • Antibodies
          • Primary Antibodies
          • Secondary Antibodies
        • Equipment
          • Slide Staining Systems
          • Tissue Microarrays
          • Tissue Processing Systems
          • Slide Scanners
          • Others
        • Reagents
          • Histological Stains
          • Blocking Sera and Reagents
          • Chromogenic Substrates
          • Fixation Reagents
          • Stabilizers
          • Others
        • Kits
      • By Application
        • Diagnostics
          • Cancer
          • Infectious Diseases
          • Cardiovascular Diseases
          • Autoimmune Diseases
          • Diabetes Mellitus
          • Others
        • Drug Testing
        • Forensic Applications
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Research Institutes
        • Others
      • By Country
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Product
        • Antibodies
          • Primary Antibodies
          • Secondary Antibodies
        • Equipment
          • Slide Staining Systems
          • Tissue Microarrays
          • Tissue Processing Systems
          • Slide Scanners
          • Others
        • Reagents
          • Histological Stains
          • Blocking Sera and Reagents
          • Chromogenic Substrates
          • Fixation Reagents
          • Stabilizers
          • Others
        • Kits
      • By Application
        • Diagnostics
          • Cancer
          • Infectious Diseases
          • Cardiovascular Diseases
          • Autoimmune Diseases
          • Diabetes Mellitus
          • Others
        • Drug Testing
        • Forensic Applications
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Research Institutes
        • Others
      • By Country
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Product
        • Antibodies
          • Primary Antibodies
          • Secondary Antibodies
        • Equipment
          • Slide Staining Systems
          • Tissue Microarrays
          • Tissue Processing Systems
          • Slide Scanners
          • Others
        • Reagents
          • Histological Stains
          • Blocking Sera and Reagents
          • Chromogenic Substrates
          • Fixation Reagents
          • Stabilizers
          • Others
        • Kits
      • By Application
        • Diagnostics
          • Cancer
          • Infectious Diseases
          • Cardiovascular Diseases
          • Autoimmune Diseases
          • Diabetes Mellitus
          • Others
        • Drug Testing
        • Forensic Applications
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Research Institutes
        • Others
      • By Country
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Product
        • Antibodies
          • Primary Antibodies
          • Secondary Antibodies
        • Equipment
          • Slide Staining Systems
          • Tissue Microarrays
          • Tissue Processing Systems
          • Slide Scanners
          • Others
        • Reagents
          • Histological Stains
          • Blocking Sera and Reagents
          • Chromogenic Substrates
          • Fixation Reagents
          • Stabilizers
          • Others
        • Kits
      • By Application
        • Diagnostics
          • Cancer
          • Infectious Diseases
          • Cardiovascular Diseases
          • Autoimmune Diseases
          • Diabetes Mellitus
          • Others
        • Drug Testing
        • Forensic Applications
      • By End User
        • Hospitals
        • Diagnostic Laboratories
        • Research Institutes
        • Others
      • By Region/Country
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Thermo Fisher Scientific, Inc.
      • Company Highlights
      • Products Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • Hoffmann-La Roche Ltd.
    • Merck KGaA
    • Danaher Corporation
    • Perkinelmer, Inc.
    • Bio-Rad Laboratories, Inc.
    • Cell Signaling Technology, Inc.
    • Bio SB
    • Agilent Technologies, Inc.
    • Abcam plc.
    • Becton, Dickinson and Company
    • Takara Bio, Inc.
    • Eagle Biosciences, Inc.
    • Biocare Medical, LLC
    • Biogenex Laboratories
    • Diagnostic Biosystems, Inc.
    • BioVision Inc.

 “*” marked represents similar segmentation in other categories in the respective section.

Frequently Asked Questions

The global immunohistochemistry (IHC) market size is estimated to be valued at US$ 2020.2 Million in 2021 and is expected to exhibit a CAGR of 7.5% between 2021 and 2028.
Increasing prevalence of chronic diseases such as cancers, cardiovascular diseases, and others, increasing global geriatric population, and increasing product launches are major driving factors for the market.
Diagnostics is the major application segment in the market.
Lack of specificity associated with IHC technology and the high cost of setup are the major factors restraining growth of the market.
Major players operating in the market include Thermo Fisher Scientific, Inc., F. Hoffmann-La Roche Ltd., Merck KGaA, Danaher Corporation, Perkinelmer, Inc., Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Bio SB, Agilent Technologies, Inc., Abcam plc., Becton, Dickinson and Company, Takara Bio, Inc., Eagle Biosciences, Inc., Biocare Medical, LLC, Biogenex Laboratories, Diagnostic Biosystems, Inc., and BioVision Inc.

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