Immunohistochemistry is a staining procedure that uses antibodies to detect and localize proteins of interest, like antigens, within the context of tissue structure. The technique is used as an ancillary method in clinical diagnostic to localize and quantify abnormal protein expressions linked to various diseases, particularly cancer. With specific tumor markers, researchers can determine tumor malignancy, stage, and grade, as well as identify and classify metastatic carcinomas of unknown primary sites. In basic research, immunohistochemistry is used to study normal tissue and organ development, tissue repair, wound healing, and explore and validate critical biomarkers. Moreover, there are many variations of immunohistochemistry staining, including IHC-frozen, IHC-paraffin, and IHC-free floating, the workflow for each method is similar, consisting of two parts: sample preparation and sample staining.
Global Immunohistochemistry market is estimated to be valued at US$ 1,463.6 million in 2022 and is expected to exhibit a CAGR of 6.6 % over the forecast period (2022-2030)
Figure 1. Global Immunohistochemistry Market Value (US$ Mn), By Region, 2022
Market players are actively focusing on partnership and collaboration, which is expected to drive growth of the global immunohistochemistry market over the forecast period.
For instance, in January 2021, Diaceutics PLC, a company that offers diagnostic tracking, laboratory mapping, testing, and other services, announced a strategic partnership with Canadian Pathology Quality Assurance, a non-profit organization, in order to boost the development of Neurotrophic Tropomyosin Receptor Kinase (NTRK) IHC proficiency testing
Figure 2. Global Immunohistochemistry Market Share (%), By Procedure Type, 2022
Increase in prevalence of chronic diseases expected to drive the market growth over the forecast period.
For instance, according to the World Health Organization (WHO) Fact sheet, February 2022, cancer is a leading cause of death worldwide, and accounted for around 10 million deaths in 2020, or nearly one in six deaths.
Moreover, according to American Cancer Society, there were an estimated 1.9 million new cancer cases diagnosed and 609,360 cancer deaths in the U.S.
| Report Coverage | Details | ||
|---|---|---|---|
| Base Year: | 2021 | Market Size in 2022: | US$ 1,463.6 Mn |
| Historical Data for: | 2017 to 2020 | Forecast Period: | 2022 to 2030 |
| Forecast Period 2022 to 2030 CAGR: | 6.6 % | 2030 Value Projection: | US$ 2448.9 Mn |
| Geographies covered: |
|
||
| Segments covered: |
|
||
| Companies covered: |
Merck KGaA, Rockland Immunochemicals, Inc., F. Hoffmann-La Roche Ltd, Thermo Fisher Scientific, PerkinElmer, Inc., Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Bio SB, Agilent Technologies, Inc., Abcam plc., Becton, Dickinson and Company, Miltenyi Biotec, Biocare Medical, LLC, Eagle Biosciences, Inc., Bio-Techne, Diagnostic Biosystems, Inc., and BioGenex. |
||
| Growth Drivers: |
|
||
| Restraints & Challenges: |
|
||
Global Immunohistochemistry Market – Impact of Coronavirus (COVID-19) Pandemic
The coronavirus (COVID-19) outbreak was first reported on December 31, 2019, in Wuhan, China. The World Health Organization declared COVID-19 a pandemic on March 11, 2020. According to the Coronavirus (COVID-19) Weekly Epidemiological Update by the World Health Organization, over 610,393,563 cases of coronavirus disease (COVID-19) were reported till September 19, 2022, across the globe.
Global supply chains have faced considerable obstacles as a result of the COVID-19 pandemic. The flow of raw supplies and finished items is still being slowed or even temporarily stopped by numerous national lockdowns, which is affecting the production process.
This also impacted the global immunohistochemistry (IHC) market slightly due to delays in the supply chain and raw material transportation.
However, according to the Nature journal, December 2020, Immunohistochemistry and in situ hybridization techniques that allow for the identification of SARS-CoV and SARS-CoV-2 viral products in formalin-fixed paraffin-embedded (FFPE) specimens would be extremely useful in the future. These various strategies for virus detection and control material synthesis can be applied to studies of coronavirus pathogenesis and therapeutic research in animal models.
Therefore, there was an impact on the supply of immunohistochemistry kits and reagents during COVID-19 pandemic. However, its application in COVID-19 research and diagnosis is expected to increase its demand ahead in the future.
Global Immunohistochemistry Market Restraint
Limitation associated with immunohistochemistry techniques is expected to hamper the market growth over the forecast period
Key Players
Major players operating in the global immunohistochemisty market include Merck KGaA, Rockland Immunochemicals, Inc., F. Hoffmann-La Roche Ltd, Thermo Fisher Scientific, PerkinElmer, Inc., Bio-Rad Laboratories, Inc., Cell Signaling Technology, Inc., Bio SB, Agilent Technologies, Inc., Abcam plc., Becton, Dickinson and Company, Miltenyi Biotec, Biocare Medical, LLC, Eagle Biosciences, Inc., Bio-Techne, Diagnostic Biosystems, Inc., and BioGenex.
In histology, immunohistochemistry (IHC) is used to identify the presence of a particular protein marker that can aid in the accurate classification and diagnosis of tumors. Antibodies are used in immunohistochemistry (IHC) to locate proteins and other antigens in tissue sections. Either chromogenic detection using a colored enzyme substrate or fluorescence detection with a fluorescent dye is used to observe antibody-antigen interaction.
Market Dynamics
The increasing prevalence of chronic diseases, rising research and development activities for the development of innovative product, and increasing adoption of inorganic growth strategies such as mergers, acquisitions, partnerships, and collaborations by key players operating in market are the major factors that are expected to drive growth of the global immunohistochemistry market over the forecast period.
For instance, in June 2022, Lupin, an India-based biopharmaceutical company, announced the opening of its first regional reference laboratory in Patna, Bihar. A wide range of standard and specialist tests in the disciplines of molecular diagnostics, cytology, microbiology, serology,hematology, immunology, and normal biochemistry can be performed at the new regional reference laboratory in Patna.
According to an article by the Elsevier Inc., published in July 2021, the contribution of non-communicable neurological disorders to total disability-adjusted life-years (DALYs) in India doubled from 4·0% in 1990 to 8·2% in 2019. In addition, the largest contributors to the total neurological disorder DALYs in India were brain stroke (37·9%), headache disorders (17·5%), epilepsy (11·3%), cerebral palsy (5·7%), and encephalitis (5·3%), in 2019.
Key features of the study:
Detailed Segmentation:
"marked represents similar segmentation in other categories in the respective section."
Joining thousands of companies around the world committed to making the Excellent Business Solutions.
View All Our Clients