Myelodysplastic Syndrome Treatment Market Insights

Rising public awareness about Myelodysplastic Syndromes (MDS) and its early diagnosis and availability of new treatment options for MDS are expected to drive growth of the market over the forecast period. Moreover, early diagnosis of MDS is important because it significantly increases the quality of life in patients, reducing the chances of recurrent blood transfusion and in more severe cases, as in 30% of the time, the evolution of the disease to leukemia. Government organizations and drug manufacturing companies are focusing on spreading awareness about the disease by providing funding and conducting awareness programs. For instance, in October 2018, Grupo Biotoscana, a Latin American biopharmaceutical company conducted campaign to honor Myelodysplastic Syndrome World Awareness Day, which is celebrated on 25th October. GBT Grupo Biotoscana launched a campaign to raise awareness and educate about disease throughout the month.

The global myelodysplastic syndrome treatment market was valued at US$ 2,324.8 million in 2018, and is expected to exhibit a CAGR of 8.9% during the forecast period (2019–2027).

Figure 1. Global Myelodysplastic Syndrome Treatment Market Share (%), By Drug Class

Myelodysplastic Syndrome Treatment  | Coherent Market Insights

Source: Coherent Market Insights Analysis (2019)

Increasing regulatory approval for drugs for treating MDS is expected to be a driving factor contributing growth of the global myelodysplastic syndrome treatment market over the forecast period

Increasing regulatory approvals is expected to drive growth of the global myelodysplastic syndrome treatment market over the forecast period. For instance, in November 2018, Lupin received the U.S. FDA approval for its Decitabine for Injection, 50 mg/vial, single-dose vial, a generic version of Otsuka Pharmaceutical Co. Ltd.'s Dacogen for Injection, 50 mg/vial, single-dose vial. Lupin’s generic version is indicated for the treatment of patients with myelodysplastic syndromes (MDS), which includes previously treated and untreated, de novo, and secondary MDS of all French-American-British subtypes.

Increasing launch and approval of Azacitidine in key region is expected to drive growth of Azacitidine segment of myelodysplastic syndrome treatment market over the forecast period. For instance, in February 2018, BeiGene, Ltd. announced the commercial availability of VIDAZ (azacitidine for injection) in China. VIDAZA is approved in China for patients with intermediate-2 / high-risk myelodysplastic syndrome (MDS), acute myeloid leukemia (AML) with 20-30% bone marrow blasts, and chronic myelomonocytic leukemia (CMML). It is marketed in China by BeiGene under an exclusive license from Celgene Corporation.

Increased complexity of MDS disease and its true diagnosis among the patients generates major hurdle in the development of effective MDS treatment, which is expected to hamper the global myelodysplastic syndrome treatment market growth

MDS represent several different conditions, as it is not just a single disease, but it is grouped together by several clinical characteristics. According to the data published in the Hematology journal of American Society of Hematology Education Program in December 2017; the type and severity of hematopoietic dysfunction in MDS are highly variable, and the kinetics of disease progression are difficult to predict.

Moreover, genetic characteristics of MDS are powerfully associated with clinical phenotype. An enhanced understanding of the regulatory logic of MDS genetics may stimulate refined and biologically based diagnostic and monitoring schema that may be integrated into clinical practice.

Global Myelodysplastic Syndrome Treatment Market- Regional Analysis

Based on region, the global myelodysplastic syndrome treatment market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa.

North America is expected to hold a dominant position in the market over the forecast period, owing to presence of major players and non-profit organizations in the region that are focused on launching new programs and awareness campaigns to educate people about gout disease and help healthcare practitioners in the  treatment of MDS. Among North America, the U.S. is expected to witness significant growth over the forecast period, owing to rising awareness among the U.S. population about MDS. For instance, according to the American Cancer Society 2018 data, the number of people diagnosed with myelodysplastic syndromes (MDS) in the U.S. each year varies between 10,000 to 30,000 and addition of around 55,000 new cases each year.

Europe is expected to witness significant growth over the forecast period, owing to rising government initiatives for diagnosis and treatment of disease. For instance, in 2014, the European LeukemiaNet WP8 promoted a program aiming at developing and continuously updating evidence- and consensus-based guidelines to provide clinical practice recommendations for standardized diagnostic and prognostic procedures and for an appropriate choice of therapeutic interventions in adult patients with primary MDS.

Figure 2: Global Myelodysplastic Syndrome Treatment Market Share (%), By Region

Myelodysplastic Syndrome Treatment  | Coherent Market Insights

Source: Coherent Market Insights Analysis (2019)

Global Myelodysplastic Syndrome Treatment Market - Competitive Landscape

Key players operating in the global myelodysplastic syndrome treatment market include Celgene Corporation, Otsuka Pharmaceutical Co., Ltd. Teva Pharmaceutical Industries Ltd., Sun Pharmaceutical Industries Limited, Dr. Reddy's Laboratories Ltd., Mylan NV, Cipla Limited, Acceleron Pharma, Inc., Aprea Therapeutics, FibroGen Inc., Onconova Therapeutics Inc., and Geron

In myelodysplastic syndrome (MDS), some of the cells from bone marrow are abnormal and have problems making new blood cells. Moreover, increasing possibility of MDS to further progress into rapidly growing cancer of bone marrow cells called acute myeloid leukemia (AML), leads to increasing efforts by key players develop highly effective therapies for MDS treatment. Moreover, awareness about the disease and its symptoms with advanced methods and techniques for early diagnosis and treatment for various forms of the MDS is expected to drive the market growth over the forecast period. Increased understanding of the pathology of the syndrome is directing the research towards developing more specialized and symptom based treatments with effective costs, so that MDS patients can avail these benefits.

Market Dynamics

Increasing prevalence of MDS is expected to increase the demand of such drugs, thereby expected to drive myelodysplastic syndrome treatment market growth over the forecast period. For instance, according to the 2015 report of American Cancer Society (ACS), the incidence rate for myelodysplastic syndrome was 13,000 new cases in the U.S. each year that occurs at a rate of 4.8 cases per 100,000 people.

Moreover, according to the 2015 report of American Cancer Society (ACS), incidence rate for myelodysplastic syndrome has witnessed an increase in the last few years as the average population is ageing every consecutive year. Moreover, the fact report of 2014-2015 published by Leukemia and Lymphoma Society suggests that the overall incidence of MDS in the U.S. by gender are 6.7 per 100,000 in male while 3.8 per 100,000 in females.

Key features of the study:

  • This report provides in-depth analysis of the global myelodysplastic syndrome treatment market, market size (US$ Mn), and compound annual growth rate (CAGR %) over the forecast period (2019 – 2027), considering 2018, as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrixes for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new technology launches or approvals, market trends, regional outlook, and competitive strategies adopted by leading players
  • It profiles leading players in the global myelodysplastic syndrome treatment market based on the following parameters – company overview, financial performance, technology portfolio, geographical presence, distribution strategies, key developments, and strategies
  • Key players covered as a part of this study include Celgene Corporation, Otsuka Pharmaceutical Co., Ltd. Teva Pharmaceutical Industries Ltd., Sun Pharmaceutical Industries Limited, Dr. Reddy's Laboratories Ltd., Mylan NV, Cipla Limited, Acceleron Pharma, Inc., Aprea Therapeutics, FibroGen Inc., Onconova Therapeutics Inc., and Geron
  • Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to future technology launches, government initiatives, technological upgradation, market expansions, and marketing tactics
  • The global myelodysplastic syndrome treatment market report caters to various stakeholders in this market, including investors, technology manufacturers, distributors, and suppliers in the global myelodysplastic syndrome treatment industry, research and consulting firms, new entrants, and financial analysts

Detailed Segmentation:

  • Global Myelodysplastic Syndrome Treatment Market, By Drug:
    • Lenalidomide
    • Decitabine
    • Azacitidine
    • Phase 3 Drugs
  • Global Myelodysplastic Syndrome Treatment Market, By Route Of Administration:
    • Injection
    • Oral
  • Global Myelodysplastic Syndrome Treatment Market, By Distribution Channel:
    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies
  • Global Myelodysplastic Syndrome Treatment Market, By Region:
    • North America
      • By Country:
        • U.S.
        • Canada
      • By Drug:
        • Lenalidomide
        • Decitabine
        • Azacitidine
        • Phase 3 Drugs
      • By Route of Administration:
        • Injection
        • Oral
      • By Distribution Channel
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
    • Europe
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
      • By Drug:
        • Lenalidomide
        • Decitabine
        • Azacitidine
        • Phase 3 Drugs
      • By Route of Administration:
        • Injection
        • Oral
      • By Distribution Channel
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
    • Asia Pacific
      • By Country:
        • Australia
        • India
        • China
        • Japan
        • ASEAN
        • South Korea
        • Rest of Asia Pacific
      • By Drug:
        • Lenalidomide
        • Decitabine
        • Azacitidine
        • Phase 3 Drugs
      • By Route of Administration:
        • Injection
        • Oral
      • By Distribution Channel
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
    • Latin America
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
      • By Drug:
        • Lenalidomide
        • Decitabine
        • Azacitidine
        • Phase 3 Drugs
      • By Route of Administration:
        • Injection
        • Oral
      • By Distribution Channel
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
    • Middle East
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
      • By Drug:
        • Lenalidomide
        • Decitabine
        • Azacitidine
        • Phase 3 Drugs
      • By Route of Administration:
        • Injection
        • Oral
      • By Distribution Channel
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
    • Africa
      • By Country/Region:
        • South Africa
        • Central Africa
        • North Africa
      • By Drug:
        • Lenalidomide
        • Decitabine
        • Azacitidine
        • Phase 3 Drugs
      • By Route of Administration:
        • Injection
        • Oral
      • By Distribution Channel
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
  • Company Profiles
    • Celgene Corporation
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Highlights
      • Strategies
    • Otsuka Pharmaceutical Co., Ltd.  
    • Teva Pharmaceutical Industries Ltd.
    • Sun Pharmaceutical Industries Limited
    • Dr. Reddy's Laboratories Ltd.
    • Mylan NV
    • Cipla Limited
    • Acceleron Pharma, Inc.
    • Aprea Therapeutics
    • FibroGen Inc.
    • Onconova Therapeutics Inc.
    • Geron

“*” marked represents similar segmentation in other categories in the respective section

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Drug
      • Market Snippet, By Route of Administration
      • Market Snippet, By Distribution Channel
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Market Trends
    • Key Developments
    • Pipeline Analysis
    • Mergers and Acquisitions
    • Regulatory Scenario
    • Reimbursement Scenario
    • PEST Analysis
  4. Global Myelodysplastic Syndrome (MDS) Treatment Market, By Drug, 2016 – 2027, (US$ Million)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Lenalidomide
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Million)
    • Decitabine
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Million)
    • Azacitidine
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Million) Corticosteroids
    • Phase 3 Drugs
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Million)
  5. Global Myelodysplastic Syndrome (MDS) Treatment Market, By Route of Administration, 2016 – 2027, (US$ Million)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Injection
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Million)
    • Oral
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Million)
      •  
  6. Global Myelodysplastic Syndrome (MDS) Treatment Market, By Distribution Channel, 2016 – 2027, (US$ Million)
    • Introduction
      • Market Share Analysis, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017 – 2027
      • Segment Trends
    • Hospital Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Million)
    • Retail Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Million)
    • Online Pharmacies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Million)
  7. Global Myelodysplastic Syndrome (MDS) Treatment Market, By Region, 2016 – 2027, (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2019 and 2027 (%)
      • Y-o-Y Growth Analysis, By Region, 2017 – 2027
      • Regional Trends
    • North America
      • Market Size and Forecast, By Drug, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Million)
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast, By Drug, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Drug, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Million)
        • China
        • Japan
        • India
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast, By Drug, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Million)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Africa
      • Market Size and Forecast, By Drug, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Country/Region, 2016 – 2027, (US$ Million)
        • North Africa
        • Central Africa
        • South Africa
    • Middle East
      • Market Size and Forecast, By Drug, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 – 2027, (US$ Million)
      • Market Size and Forecast, By Country, 2016 – 2027, (US$ Million)
        • GCC
        • Israel
        • Rest of Middle East
  8. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • Celgene Corporation
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Otsuka Pharmaceutical Co., Ltd.  
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Teva Pharmaceutical Industries Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Sun Pharmaceutical Industries Limited
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Dr. Reddy's Laboratories Ltd.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Mylan NV
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Cipla Limited
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Acceleron Pharma, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Aprea Therapeutics
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • FibroGen Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Onconova Therapeutics Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Geron
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
    • Analyst Views
  9. Section
    • References
    • Research Methodology
    • About us and Sales Contact

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