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Phase-Xs | Biologics & Biosimilars | Coherent Market Insights

Impact Analysis of Covid-19

The complete version of the Report will include the impact of the COVID-19, and anticipated change on the future outlook of the industry, by taking into the account the political, economic, social, and technological parameters.

Myeloproliferative neoplasm (MPN) is a group of rare diseases, in which the bone marrow produces excess blood cells. It can be white blood cells, red blood cells, or platelets. The overproduction of blood cells by the bone marrow creates obstacle in the smooth flow of blood, which leads to various symptoms such as progressive cytopenias, cachexia, and weight loss, and splenomegaly. There are various types of myeloproliferative neoplasms, which include chronic myelogenous leukemia, polycythemia vera, essential thrombocythemia, and others. These conditions are developed gradually over a period of time, and most of the people are diagnosed after the age of 60.

Figure 1. Global Myeloproliferative Neoplasm Drugs Market Value (US$ Mn), 2016-2027

Myeloproliferative Neoplasm Drugs  | Coherent Market Insights

The global myeloproliferative neoplasm drugs market size is estimated to be valued at US$ 8,379.5 million in 2020 and is expected to exhibit a CAGR of 3.9% over the forecast period (2020-2027).

The increasing incidence of myeloproliferative neoplasms is expected to drive the growth of the global myeloproliferative neoplasm drugs market over the forecast period. According to the article in journal of Multidisciplinary Digital Publishing Institute (MDPI) in July 2020, the estimated annual incidence rates for polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis are 0.84, 1.03, and 0.47 per 100,000 population globally and the prevalence is much higher, particularly for PV and ET, as mortality rates are relatively low.

Moreover, according to the article published in National Centre for Biotechnology Information (NCBI) in July 2016, the incidence of myeloproliferative neoplasms is approximately 0.5-6 per 100,000 population globally.

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Myeloproliferative Neoplasm Drugs Market Report Coverage

Report Coverage Details
Base Year: 2019 Market Size in 2020: US$ 8,379.5 Mn
Historical Data for: 2016 to 2019 Forecast Period: 2020 to 2027
Forecast Period 2020 to 2027 CAGR: 3.9 % 2027 Value Projection: US$ 10,966.8 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC, Israel, and Rest of the Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Drug Class: Demethylation Agents, Tyrosine kinase Inhibitor, Multikinase Inhibitors, JAK2 Inhibitor, Others
  • By Indication:
    • Ph+ Chronic myelogenous leukemia (CML)
    • Ph- Myeloproliferative Neoplasms (MPNs): Myelofibrosis (MF), Polycythemia Vera (PV), Essential thrombocythemia (ET).
  • By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies.
Companies covered:

Novartis International AG, PharmaEssentia Corporation, Bristol Myers Squibb, Pfizer, Inc., Takeda Pharmaceutical Company Limited, Incyte, Johnson & Johnson, Teva Pharmaceutical Industries Ltd., F. Hoffmann-La Roche AG, Gamida Cell, Sierra Oncology, Inc., CTI BioPharma Corp., Imago BioSciences, AbbVie Inc., and Constellation Pharmaceuticals

Growth Drivers:
  • Increasing incidence of myeloproliferative neoplasm
  • Presence of strong pipeline products
  • Increasing drug approvals from regulatory authorities
Restraints & Challenges:
  • High cost of treatment therapy for myeloproliferative neoplasm

Global Myeloproliferative Neoplasm Drugs Market- Impact of Coronavirus (Covid-19) Pandemic

Following the outbreak of COVID-19 in December 2019, the disease has spread to over 100 countries across the globe and the World Health Organization declared it a public health emergency. According to the World Health Organization’s report, manifestation of coronavirus (COVID-19) has resulted in more than 105 million infected individuals worldwide as of February 5, 2021.

COVID-19 outbreak started from Wuhan, China and has spread across continents, affecting various industries globally. Supply of key materials has been severely disrupted due to forced quarantine, and lack of labor and raw materials. As the link between regional warehouses is not smooth, the transportation of raw materials between regions cannot be carried out successfully. This shortage of raw materials and components have affected the supply chain of the global myeloproliferative neoplasm drugs market.

Moreover, due to severe shortage of medical resources at the front line, only patients diagnosed with serious conditions can be hospitalized. Unfortunately, the pathogenic mechanism of the virus has not been identified completely, therefore, there is no specific drug and treatment except for symptomatic and supportive treatments. Respiratory support devices such as life-support machines, atomizer, oxygen generators, and monitors are primary clinical treatment medical devices. Thus, from diagnosis to cure, the need for instruments for measuring temperature, nucleic acid diagnostic kit, antiviral medical products, and life-support machine have increased consistently.

Figure 2. Global Myeloproliferative Neoplasm Drugs Market Share (%) by Region, 2020

Myeloproliferative Neoplasm Drugs  | Coherent Market Insights

In North America, the increasing number of drug approvals is expected to boost growth of the global myeloproliferative neoplasm drugs market over the forecast period. For instance, in April 2020, Janssen Pharmaceutical Company, a subsidiary of Johnson & Johnson, received the U.S. Food and Drug Administration (FDA) approval for IMBRUVICA (ibrutinib) in combination with rituximab for the treatment of patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).

Moreover, in Asia Pacific, rise in the research and development activities by market players is expected to create a lucrative environment for the market growth. For instance, in May 2020, Hutchison China MediTech, a China-based biopharmaceutical company, initiated a Phase 1 clinical trial to evaluate the safety, efficacy, and pharmacokinetics of HMPL-306 in patients with relapsed/refractory myeloid leukemia/neoplasms with IDH1 and/or IDH2 mutation.

Major players operating in the global myeloproliferative neoplasm drugs market include Novartis International AG, PharmaEssentia Corporation, Bristol - Myers Squibb, Pfizer, Inc., Takeda Pharmaceutical Company Limited, Incyte, Johnson & Johnson, Teva Pharmaceutical Industries Ltd., F. Hoffmann-La Roche AG, Gamida Cell, Sierra Oncology, Inc., CTI BioPharma Corp., Imago BioSciences, AbbVie Inc., and Constellation Pharmaceuticals.

Myeloproliferative neoplasms (MPNs) are a type of rare blood cancers, which leads to production of excess red blood cells, white blood cells, or platelets in the bone marrow of individuals. Myelo refers to bone marrow and spinal cord of the individual and proliferative describes the rapid growth of blood cells, whereas neoplasm describes the abnormal and uncontrolled growth of cells in patients. The overproduction of blood cells is often associated with a somatic mutation, for example, the over production of JAK2 (Janus kinase 2) leads to chronic myeloproliferative disorders.  The various drug classes indicated for the treatment of myeloproliferative neoplasm are demethylation agents, tyrosine kinase inhibitor, multikinase inhibitors, JAK2 inhibitor, and others.

Market Dynamics

Key companies are focusing on strategies such as mergers and acquisitions, which is expected to drive the global myeloproliferative neoplasm drugs market growth. For instance, in January 2019, Takeda Pharmaceutical Company Limited acquired Shire Inc (a biopharmaceutical company in U.K.),to expand its geographical presence in the market and enhance its product portfolio through research and development activities.

Moreover, key players are focusing on product launches and product approvals to strengthen their presence in the global myeloproliferative neoplasm drugs market. For instance, in November 2018, Pfizer Inc. received the U.S. Food and Drug Administration approval for Daurismo for use in adults with acute myeloid leukemia (AML) in 75 years or older patients.

Furthermore, in December 2017, Pfizer Inc. received the U.S. Food and Drug Administration (FDA) approval for a supplemental New Drug Application (sNDA) to expand the indication of BOSULIF (bosutinib) to include adult patients with newly-diagnosed chronic phase Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML).

Key features of the study:

  • This report provides in-depth analysis of the global myeloproliferative neoplasm drugs market, and provides market size (US$ Mn) and compound annual growth rate (CAGR) (%) for the forecast period (2020–2027)
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market. It provides valuable insights about market drivers, restraints, opportunities, country outlook, and competitive strategies adopted by the leading players.
  • It profiles leading players in the global myeloproliferative neoplasm drugs market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, key developments, and future plans
  • Insights from this report would allow marketers and management authorities of companies to make informed decisions with respect to future market expansion and marketing tactics
  • The global myeloproliferative neoplasm drugs market report caters to various stakeholders in this industry, including investors, product developers and manufacturers, distributors, healthcare organizations, research institutes, new entrants, and financial analysts
  • Stakeholders would greatly benefit in decision making through various strategy matrices used in analyzing the global myeloproliferative neoplasm drugs market

Detailed Segmentation:

  • Global Myeloproliferative Neoplasm Drugs Market, By Drug Class:
    • Demethylation Agents
    • Tyrosine kinase Inhibitor
    • Multikinase Inhibitors
    • JAK2 Inhibitor
    • Others
  • Global Myeloproliferative Neoplasm Drugs Market, By Indication:
    • Ph+ Chronic myelogenous leukemia (CML)
    • Ph- Myeloproliferative Neoplasms (MPNs)
      • Myelofibrosis (MF)
      • Polycythemia Vera (PV)
      • Essential thrombocythemia (ET)
  • Global Myeloproliferative Neoplasm Drugs Market, By Distribution Channel:
    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies
  • Global Myeloproliferative Neoplasm Drugs Market, By Region:
    • North America
      • By Drug Class:
        • Demethylation Agents
        • Tyrosine kinase Inhibitor
        • Multikinase Inhibitors
        • JAK2 Inhibitor
        • Others
      • By Indication:
        • Ph+ Chronic myelogenous leukemia (CML)
        • Ph- Myeloproliferative Neoplasms (MPNs)
          • Myelofibrosis (MF)
          • Polycythemia Vera (PV)
          • Essential thrombocythemia (ET)
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • U.S.
        • Canada
    • Latin America
      • By Drug Class:
        • Demethylation Agents
        • Tyrosine kinase Inhibitor
        • Multikinase Inhibitors
        • JAK2 Inhibitor
        • Others
      • By Indication:
        • Ph+ Chronic myelogenous leukemia (CML)
        • Ph- Myeloproliferative Neoplasms (MPNs)
          • Myelofibrosis (MF)
          • Polycythemia Vera (PV)
          • Essential thrombocythemia (ET)
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Drug Class:
        • Demethylation Agents
        • Tyrosine kinase Inhibitor
        • Multikinase Inhibitors
        • JAK2 Inhibitor
        • Others
      • By Indication:
        • Ph+ Chronic myelogenous leukemia (CML)
        • Ph- Myeloproliferative Neoplasms (MPNs)
          • Myelofibrosis (MF)
          • Polycythemia Vera (PV)
          • Essential thrombocythemia (ET)
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Drug Class:
        • Demethylation Agents
        • Tyrosine kinase Inhibitor
        • Multikinase Inhibitors
        • JAK2 Inhibitor
        • Others
      • By Indication:
        • Ph+ Chronic myelogenous leukemia (CML)
        • Ph- Myeloproliferative Neoplasms (MPNs)
          • Myelofibrosis (MF)
          • Polycythemia Vera (PV)
          • Essential thrombocythemia (ET)
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country:
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Drug Class:
        • Demethylation Agents
        • Tyrosine kinase Inhibitor
        • Multikinase Inhibitors
        • JAK2 Inhibitor
        • Others
      • By Indication:
        • Ph+ Chronic myelogenous leukemia (CML)
        • Ph- Myeloproliferative Neoplasms (MPNs)
          • Myelofibrosis (MF)
          • Polycythemia Vera (PV)
          • Essential thrombocythemia (ET)
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country/Region:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Drug Class:
        • Demethylation Agents
        • Tyrosine kinase Inhibitor
        • Multikinase Inhibitors
        • JAK2 Inhibitor
        • Others
      • By Indication:
        • Ph+ Chronic myelogenous leukemia (CML)
        • Ph- Myeloproliferative Neoplasms (MPNs)
          • Myelofibrosis (MF)
          • Polycythemia Vera (PV)
          • Essential thrombocythemia (ET)
      • By Distribution Channel:
        • Hospital Pharmacies
        • Retail Pharmacies
        • Online Pharmacies
      • By Country/Region:
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Novartis International AG.*
      • Company Overview
      • Material Portfolio
      • Financial Performance
      • Key Highlights
      • Market Strategies
    • Bristol - Myers Squibb
    • Pfizer, Inc.
    • Takeda Pharmaceutical Company Limited
    • Incyte
    • Johnson & Johnson
    • Teva Pharmaceutical Industries Ltd.
    • F. Hoffmann-La Roche AG
    • Gamida Cell
    • Sierra Oncology, Inc.
    • CTI BioPharma Corp.
    • Imago BioSciences
    • AbbVie Inc.
    • Constellation Pharmaceuticals

 “*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Drug Class
      • Market Snippet, By Indication
      • Market Snippet, By Distribution Channel
      • Market Snippet, By Region
      • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Drivers
    • Restraints
    • Opportunities
    • Impact Analysis
    • Key Developments
    • Product Launch/ Approvals
    • Mergers, Acquisition & Collaboration
    • Pipeline Analysis
    • Regulatory Scenario
    • PEST Analysis
    • Epidemiology
    • Market Share Analysis          
  4. Global Myeloproliferative Neoplasm Drugs Market - Impact of Coronavirus (Covid-19) Pandemic
    • Supply Side and Demand Side Analysis
    • COVID-19 Impact on Overall Healthcare Sector
    • COVID-19 Impact on Clinical Trials and Drug Development
    • COVID-19 Impact on Cancer Treatment
  5. Global Myeloproliferative Neoplasm Drugs Market, By Drug Class, 2016–2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017–2027
    • Introduction
    • Market size and forecast, and Y-o-Y Growth, 2020-2027, (US$ Mn)
    • Segment Trends
      • Demethylation Agents
        • Introduction
        • Market size and forecast, and Y-o-Y Growth, 2020-2027, (US$ Mn)
      • Tyrosine kinase Inhibitor
        • Introduction
        • Market size and forecast, and Y-o-Y Growth, 2020-2027, (US$ Mn)
      • Multikinase Inhibitors
        • Introduction
        • Market size and forecast, and Y-o-Y Growth, 2020-2027, (US$ Mn)
      • JAK2 Inhibitor
        • Introduction
        • Market size and forecast, and Y-o-Y Growth, 2020-2027, (US$ Mn)
      • Others
        • Introduction
        • Market size and forecast, and Y-o-Y Growth, 2020-2027, (US$ Mn)
  6. Global Myeloproliferative Neoplasm Drugs Market, By Indication, 2016 – 2027, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017– 2027
      • Segment Trends
        • Ph+ Chronic myelogenous leukemia (CML)
          • Introduction
          • Market size and forecast, and Y-o-Y Growth, 2020-2027, (US$ Mn)
        • Ph- Myeloproliferative Neoplasms (MPNs)
          • Introduction
          • Market size and forecast, and Y-o-Y Growth, 2020-2027, (US$ Mn)
            • Myelofibrosis (MF)
            • Polycythemia Vera (PV)
            • Essential thrombocythemia (ET)
  7. Global Myeloproliferative Neoplasm Drugs Market, By Distribution Channel, 2016–2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, 2017– 2027
      • Segment Trends
        • Hospital Pharmacies
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2020 – 2027, (US$ Mn)
        • Retail Pharmacies
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2020 – 2027, (US$ Mn)
        • Online Pharmacies
          • Introduction
          • Market Size and Forecast, and Y-o-Y Growth, 2020 – 2027, (US$ Mn)
  8. Global Myeloproliferative Neoplasm Drugs Market, By Region, 2016–2027 (US$ Mn)
    • Introduction
      • Market Share Analysis, By Country, 2020 and 2027 (%)
      • Y-o-Y Growth Analysis, For Countries, 2017–2027
    • North America
      • Introduction
      • Market Size and Forecast, By Drug Class, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2020-2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2020–2027 (US$ Mn)
        • U.S.
        • Canada
    • Latin America
      • Introduction
      • Market Size and Forecast, By Drug Class, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2020-2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2020–2027 (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Introduction
      • Market Size and Forecast, By Drug Class, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2020-2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2020–2027 (US$ Mn)
        • Germany
        • U.K.
        • France       
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Introduction
      • Market Size and Forecast, By Drug Class, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2020-2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2020–2027 (US$ Mn)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • Introduction
      • Market Size and Forecast, By Drug Class, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2020-2027 (US$ Mn)
      • Market Size and Forecast, By Country, 2020–2027 (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Introduction
      • Market Size and Forecast, By Drug Class, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Indication, 2020–2027 (US$ Mn)
      • Market Size and Forecast, By Distribution Channel, 2020-2027 (US$ Mn)
      • Market Size and Forecast, By Country/Region, 2020–2027 (US$ Mn)
        • South Africa
        • Central Africa
        • North Africa
  9. Competitive Landscape
    • Company Profiles
      • Novartis International AG
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • PharmaEssentia Corporation
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Bristol - Myers Squibb
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Pfizer, Inc.
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Takeda Pharmaceutical Company Limited
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Incyte
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Johnson & Johnson
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Teva Pharmaceutical Industries Ltd.
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • F. Hoffmann-La Roche AG
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Gamida Cell
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Sierra Oncology, Inc.
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • CTI BioPharma Corp.
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Imago BioSciences
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • AbbVie Inc.
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Constellation Pharmaceuticals
        • Company Overview
        • Clinical Trial Phase Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies

*Browse 34 market data tables and 33 figures on "Myeloproliferative Neoplasm Drugs Market– Global forecast to 2027”.

FAQgrowicon

Frequently Asked Questions

The global myeloproliferative neoplasm drugs market size is estimated to be valued at US$ 8,379.5 million in 2020 and is expected to exhibit a CAGR of 3.9% during the forecast period.
Increasing incidence of myeloproliferative neoplasm and presence of strong pipeline products are expected to drive growth of the market.
Tyrosine kinase inhibitor segment is estimated to hold major market share in 2020, as market players are focusing on obtaining drug approvals from regulatory authorities for treating myeloproliferative neoplasms.
Ph+ Chronic myelogenous Leukemia (CML) segment is estimated to hold major market share in 2020, owing to the increasing prevalence of chronic myeloid leukemia (CML).
Hospital pharmacies segment is estimated to hold major market share in 2020, owing to increasing utilization of healthcare resources such as treatments and drugs for myeloproliferative neoplasms (MPNs).
North America market is estimated to generate highest revenue share in 2020 in the market.
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