Saline Laxatives Market, by Age Group (Pediatric and Adult), by Route of Administration (Oral and Rectal), by Distribution Channel (Hospital Pharmacy, Retail Pharmacy and Online Pharmacy), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Trends, and Forecast to 2026

  • Published On : Oct 2018 |
  • Pages : 165 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Saline Laxatives Market – Insights

Saline laxatives are soluble inorganic salts that contain multivalent cations or anions. Examples of saline laxatives include citrate salts (Royvac), magnesium preparations (Phillips’ Milk of Magnesia), sulfate salts, and sodium phosphate. A saline laxative is categorized as a hyperosmotic drug, which works by pulling excess water into the bowels from tissues. This action softens the stools and leads to bowel movements. Saline laxatives can be combined with other types of laxatives in a combination medication.

The choice of saline laxative (magnesium sulfate, magnesium hydroxide, magnesium citrate, sodium sulfate, sodium phosphate) is random. For instance, in patients with either cardiac or renal dysfunction, excessive absorption of phosphorus, sodium, or magnesium can lead to electrolyte and volume overload and over use of laxative can cause dehydration.

The global saline laxatives market size was valued at US$ 317.7 million in 2018, and is expected to witness a CAGR of 6.9% over the forecast period (2018 – 2026).

Global Saline Laxatives Market Share (%) Analysis, By Route of Administration, 2018

Source: Coherent Market Insights Analysis (2018)

Increasing prevalence of chronic constipation is expected to drive the saline laxatives market growth

Increasing prevalence of constipation coupled with sedentary lifestyle, consumption of low fluid and fiber diet and rising geriatric population are major factors expected to drive the global saline laxative market growth. According to a National Center for Biotechnology Information (NCBI) study 2016, chronic constipation is a common complaint encountered by both gastroenterologists and primary care physicians, with prevalence estimates ranging from 1% to 8% among the North American population. Moreover, constipation occurs more frequently in women, with a female/male ratio ranging from 1.01 to 3.77.

The burden of chronic constipation also affects work productivity, employment, and social activities. According to the Canadian Journal of Gastroenterology and Hepatology 2007 study, among patients suffering from chronic constipation, 30% believe that they were less productive at work or at school, 13% missed work or school days, and nearly 10% were late or had to leave work or school due to their symptoms. Therefore, demand for saline laxatives is significantly boosting with increasing cases of chronic constipation.

Saline Laxatives Market Restraints

However, potential side effects from increased dose of saline laxatives can limit the saline laxatives market growth. Laxative abuse can lead to serious dysfunction of bowel motility such as cathartic colon, intestinal paralysis, lazy or laxative gut, pancreatitis, irritable bowel syndrome, and other problems.

According to the U.S. Food and Drug Administration (FDA) 2014 publication, more than one dose of Over-The-Counter (OTC) sodium phosphate drugs in 24 hours to treat constipation can cause rare but serious harm to the heart and kidneys and can even cause death. OTC sodium phosphate drug products include enemas used rectally and oral solutions taken orally.

Young children, individuals more than 55 years of age, and patients suffering from dehydration, kidney diseases, bowel obstruction or inflammation can be at high risk for potential adverse events when the recommended dose of saline laxative is exceeded.

Saline Laxatives Market - Regional Insights

On the basis of region, the global saline laxatives market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America saline laxative market is expected to foresee increase in revenue share, owing to increasing constipation related emergency in regional hospitals. For instance, according to a study published in a journal in 2015, national cost of constipation-related emergency department visits in the U.S. increased by 121.4% from 723,886,977 in 2006 to 1.6 billion in 2011.

Europe saline laxative market is anticipated to grow at significant rate, owing to increasing spending over the use of laxatives. For instance, according to the Health and Social Care Information Centre, in 2013, in the UK more than 17 million laxative items were prescribed. According to a study published by a journal, in Norway, a population of around 5.2 million, spent US$ 22.1 million in 2014, on laxatives.

Global Saline Laxatives Market Value (US$ Mn) & Y-o-Y Growth (%)

   

 Source: Coherent Market Insights Analysis (2018)

Key players operating in the global saline laxatives market include Beutlich Pharmaceuticals LLC, Bayer AG, C.B. Fleet Company, Inc., Salix Pharmaceuticals, Safeway Inc., Supervalu Inc., The Kroger Company, and Walgreen Co.

Saline laxatives are used to treat constipation or to cleanse the colon in preparation for a colonoscopy. Saline laxative work by absorbing water into the intestine, which softens the stool. These drugs rapidly increase the frequency of complete bowel actions, reduce constipation-associated symptoms and improve disease-related quality of life. Mild saline laxatives such as milk of magnesia and oral magnesium hydroxide have been used to treat constipation during pregnancy.

Market Dynamics

Increasing number of constipation incidences coupled with rising geriatric population base worldwide is the major factor driving the saline laxatives market growth. Low fluid and fibre diet intake may also play a major role in onset of constipation. According to the AGA Journal 2011 data, constipation affects 12% to 19% of Americans every year; its prevalence increases with age and it affects women more than men. Constipation causes psychological impairment, social distress, sexual dysfunction, altered interpersonal relationship, and impairment in quality of life. It has a major impact on social and economic burden. As per U.S. FDA, Americans spend more than US$ 700 million annually on over-the-counter laxatives.

Constipation during pregnancy is a common problem. According to the BMC journal 2012 data, the reported prevalence of constipation in pregnant women varies between 11 to 38% and occurs mostly during the third trimester, although symptoms can be present from 12 weeks gestation. However, most obstetricians advise avoiding laxatives during pregnancy and prescribe stool softeners instead due to its potential side effects.

Side effects associated with over dose of saline laxative including cathartic colon, intestinal paralysis, lazy or laxative gut, pancreatitis, irritable bowel syndrome can confine the saline laxative market growth during the forecast period. In 2014, the FDA issued a warning about the use of saline laxatives. Saline laxatives that contain the active ingredient sodium phosphate can lead to abnormal levels of electrolytes, dehydration, heart and kidney problems, and death.

Key features of the study:

  • This report provides in-depth analysis of the saline laxatives market, market size (US$ Mn), and Compound Annual Growth Rate (CAGR (%)) for the forecast period: 2019 – 2026, considering 2018, as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by leading players
  • It profiles key players in the global saline laxatives market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments, and strategies
  • Key players covered as a part of this study include Beutlich Pharmaceuticals LLC, Bayer AG, C.B. Fleet Company, Inc., Salix Pharmaceuticals, Safeway Inc., Supervalu Inc., The Kroger Company, and Walgreen Co.
  • Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to their future product launch, governmental initiatives, technological up-gradation, market expansion, and marketing tactics
  • The global saline laxatives market report caters to various stakeholders in this industry, including investors, product manufacturers, distributors, and suppliers for saline laxatives market, research and consulting firms, new entrants, and financial analysts

 

Detailed Segmentation:

  • Global Saline Laxatives Market, By Age Group:
    • Pediatric
    • Adult
  • Global Saline Laxatives Market, By Route of Administration:
    • Oral
    • Rectal
  • Global Saline Laxatives Market, By Distribution Channel:
    • Hospital Pharmacy
    • Retail Pharmacy
    • Online Pharmacy
  • Global Saline Laxatives Market, By Region:
    • North America
      • By Country:
        • U.S.
        • Canada
      • By Age Group:
        • Pediatric
        • Adult
      • By Route of Administration:
        • Oral
        • Rectal
      • By Distribution Channel:
        • Hospital Pharmacy
        • Retail Pharmacy
        • Online Pharmacy
    • Europe
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
      • By Age Group:
        • Pediatric
        • Adult
      • By Route of Administration:
        • Oral
        • Rectal
      • By Distribution Channel:
        • Hospital Pharmacy
        • Retail Pharmacy
        • Online Pharmacy
    • Asia Pacific
      • By Country:
        • Australia
        • India
        • China
        • Japan
        • ASEAN
        • South Korea
        • Rest of Asia Pacific
      • By Age Group:
        • Pediatric
        • Adult
      • By Route of Administration:
        • Oral
        • Rectal
      • By Distribution Channel:
        • Hospital Pharmacy
        • Retail Pharmacy
        • Online Pharmacy
    • Latin America
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
      • By Age Group:
        • Pediatric
        • Adult
      • By Route of Administration:
        • Oral
        • Rectal
      • By Distribution Channel:
        • Hospital Pharmacy
        • Retail Pharmacy
        • Online Pharmacy
    • Middle East
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
      • By Age Group:
        • Pediatric
        • Adult
      • By Route of Administration:
        • Oral
        • Rectal
      • By Distribution Channel:
        • Hospital Pharmacy
        • Retail Pharmacy
        • Online Pharmacy
    • Africa
      • By Country:
        • South Africa
        • Central Africa
        • North Africa
      • By Age Group:
        • Pediatric
        • Adult
      • By Route of Administration:
        • Oral
        • Rectal
      • By Distribution Channel:
        • Hospital Pharmacy
        • Retail Pharmacy
        • Online Pharmacy
  • Company Profiles
    • Beutlich Pharmaceuticals LLC*
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Highlights
      • Strategies
    • Bayer AG
    • B. Fleet Company, Inc.
    • Salix Pharmaceuticals
    • Safeway Inc.
    • Supervalu Inc.
    • The Kroger Company
    • Walgreen Co.

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objective and Assumption
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Overview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Age Group
      • Market Snippet, By Route of Administration
      • Market Snippet, By Distribution Channel
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Market Trends
    • Key Developments
    • Regulatory Landscape
    • Epidemiology Analysis
    • PORTER’S Five Forces
  4. Global Saline Laxatives Market, By Age Group, 2018 - 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Pediatric
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2026, (US$ Million)
    • Adult
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2026, (US$ Million)
  5. Global Saline Laxatives Market, By Route of Administration, 2018 - 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Oral
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2026, (US$ Million)
    • Rectal
      • Introduction  
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2026, (US$ Million)
  6. Global Saline Laxatives Market, By Distribution Channel, 2018 - 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Hospital Pharmacy
      •  Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2026, (US$ Million)
    • Retail Pharmacy
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2026, (US$ Million)
    • Online Pharmacy
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 - 2026, (US$ Million)
  7. Global Saline Laxatives Market, By Region, 2018 - 2026, (US$ Million)
    • Introduction
      • Market Share Analysis, By Region, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, By Region, 2016 - 2026
      • Regional Trends
    • North America
      • Market Size and Forecast, By Age Group, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast, By Age Group, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • U.K.
        • Germany
        • Italy
        • France
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Age Group, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • China
        • Japan
        • India
        • ASEAN
        • Australia
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast, By Age Group, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Africa
      • Market Size and Forecast, By Age Group, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • Northern Africa
        • Central Africa
        • South Africa
    • Middle East
      • Market Size and Forecast, By Age Group, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Route of Administration, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Distribution Channel, 2016 - 2026, (US$ Million)
      • Market Size and Forecast, By Country, 2016 - 2026, (US$ Million)
        • GCC Countries
        • Israel
        • Rest of Middle East
  8. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      • Beutlich Pharmaceuticals LLC
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Bayer AG
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • C.B. Fleet Company, Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Salix Pharmaceuticals
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Safeway Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Supervalu Inc.
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • The Kroger Company
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
      • Walgreen Co
        • Company Overview
        • Product Portfolio
        • Financial Performance
        • Recent Highlights
        • Strategies
    • Analyst Views
  9. Section
    • References
    • Research Methodology
    • About Us and Sales Contact

*Browse 22 market data tables and 25 figures on "Saline Laxatives Market” - Global forecast to 2026”.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
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