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  • Published On : Nov 2021
  • Code : CMI4774
  • Industry : Pharmaceutical
  • Pages : 191
  • Formats :

Yellow fever is an epidemic-prone disease caused by the bite of an infected mosquito that can be prevented by vaccination. Yellow fever is caused by an arbovirus (a virus spread by vectors such as mosquitoes, ticks, or other arthropods) that is spread to humans by infected mosquitoes (Aedes and Haemagogus). These mosquitoes breed in houses, in forests or jungles, or in both habitats. Yellow fever is a high-threat disease with a risk of spreading globally, thereby posing a  threat to global health security. The common symptoms of yellow fever include headache, fever, nausea, and vomiting. In severe cases, yellow fever can also affect some organs such as the heart, kidney, and liver.

The global yellow fever treatment market is estimated to be valued at US$ 470.5 million in 2021 and is expected to exhibit a CAGR of 3.7% during the forecast period (2021-2028).

Figure 1.Global Yellow Fever Treatment Market Share (%) in Terms of Value, by Treatment Type, 2021

Yellow Fever Treatment  | Coherent Market Insights

The increasing prevalence of yellow fever is expected to drive the market growth during the forecast period

The increasing prevalence of yellow fever is expected to drive the market growth of the global yellow fever treatment over the forecast period. For instance, according to an article published in ‘Journal of Medical Virology’, yellow fever affects 84,000 to 170,000 people in Africa each year, with 29,000–60,000 deaths. 

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Yellow Fever Treatment Market Report Coverage

Report Coverage Details
Base Year: 2020 Market Size in 2021: US$ 470.5 Mn
Historical Data for: 2017 to 2020 Forecast Period: 2021 to 2028
Forecast Period 2021 to 2028 CAGR: 3.7% 2028 Value Projection: US$ 607.6 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Transmission Type: Sylvatic Yellow Fever, Intermediate Yellow Fever, Urban Yellow Fever
  • By Treatment Type: Vaccines, Medications, Others
  • By Application: Hospitals, Clinics, Community Health Centers, Others
Companies covered:

Sanofi Pasteur SA, Janssen, Pfizer Inc., BIOCRYST PHARMACEUTICALS, INC., Tychan Pte. Ltd., Johnson & Johnson Services, Inc., Takeda Pharmaceutical Company Limited, Bayer AG, GlaxoSmithKline plc, Bio-Manguinhos, Institut Pasteur de Dakar, and FSUE Chumakov

Growth Drivers:
  • Increasing prevalence of yellow fever
  • Increasing research and development activities
Restraints & Challenges:
  • Limited treatment options
  • Severity associated with taking wrong medications due to misdiagnosis or incorrect self-diagnosis

Figure 2.Global Yellow Fever Treatment Market Share (%), by Application, 2021

Yellow Fever Treatment  | Coherent Market Insights

The increasing use of technology such as artificial intelligence is expected to drive the market growth during the forecast period

Advanced technologies and the use of artificial intelligence are expected to drive the global yellow fever treatment market growth during the forecast period. For instance, in September 2021, scientists from the ‘Research Centre of Biotechnology’ of the Russian Academy of Sciences developed a technology and synthesized five of the most promising compounds and investigated their activity using artificial intelligence. The molecules they chose were related to the derivatives of pyrazosulphonamide.

The above research was conducted in cooperation with Collaborations Pharmaceuticals, Inc., a private company specialized in innovative therapeutics for multiple rare and infectious diseases (based in the U.S.). The team used a predictive computer model in combination with several machine learning methods. For model training, they relied on in vitro screening data and information available in existing databases to select and identify the ideal molecule features for the desired activity. By using these computational models, they predicted their bioactivity before testing them in vitro using NIAID resources.

Global Yellow Fever Treatment Market – Impact of Coronavirus (COVID-19) Pandemic

The COVID-19 disease has spread to over 100 countries since its outbreak in December 2019. On January 30, 2020, the World Health Organization (WHO) declared COVID-19 a public health emergency.

The COVID-19 pandemic has impacted clinical trials in a significant way. Various trials have been paused, and researchers have been facing a lot of challenges in visiting remote areas and performing the necessary laboratory and other study assessments required for carrying out the trials effectively.

Furthermore, key players operating in the global yellow fever treatment market also faced various challenges due to the COVID-19 pandemic. The major challenges include the supply of raw materials required for manufacturing drugs due to transportation disruption. Moreover, distributors are facing irregular product demand from retailers due to an increase in the number of patients suffering from COVID-19.

Global Yellow Fever Treatment Market: Restraint

The major factors that hinder the growth of the global yellow fever treatment market include limited treatment options and severity associated with taking wrong medications due to misdiagnosis or incorrect self-diagnosis.

Key Players

Major players operating in the global yellow fever treatment market include Sanofi Pasteur SA, Janssen, Pfizer Inc., BIOCRYST PHARMACEUTICALS, INC., Tychan Pte. Ltd., Johnson & Johnson Services, Inc., Takeda Pharmaceutical Company Limited, Bayer AG, GlaxoSmithKline plc, Bio-Manguinhos, Institut Pasteur de Dakar, and FSUE Chumakov.

Yellow fever is a serious disease spread by Aedes aegypti mosquitoes, which also transmit dengue and Zika viruses. Mosquitoes normally breed in tropical rainforests, semi-humid environments, and humid environments, as well as around bodies of still water. Increased contact between humans and infected mosquitoes, specifically in areas where people haven’t been vaccinated for yellow fever, can create small-scale epidemics. The WHO estimates that 50% of people who develop severe symptoms of this condition die. Older adults and those with compromised immune systems are at a risk for serious complications. The common symptoms of yellow fever include headache, nausea, fever, and vomiting. In severe cases, yellow fever affects some key organs such as the heart, kidney, and liver.

Market Dynamics

The increasing research and studies on yellow fever are expected to drive the global yellow fever treatment market growth during the forecast period. For instance, the Epicentre study, in collaboration with the Kenya Medical Research Institute, Institut Pasteur de Dakar, and WHO, carried out a randomized, double-blind trial in Mbarara, Kenya, Kilifi, and Uganda. The trial was carried out between November 6, 2017 and February 21, 2018. During this period, researchers administered one-fifth of a standard dose of yellow fever vaccine to about 960 adults between the ages of 18 and 59 years. In this study, it was found that giving people just one-fifth of a yellow fever vaccine was as effective as giving them a full dose. This means that more lives can be saved during outbreaks of the deadly disease. This study was led by Epicentre, the research arm of Médecins Sans Frontières / Doctors without Borders (MSF).

Key features of the study:

  • This report provides an in-depth analysis of the global yellow fever treatment market, market size (US$ Mn), and compound annual growth rate (CAGR%) for the forecast period (2021–2028), considering 2020 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the global yellow fever treatment market  based on the following parameters – company highlights, products portfolio, key highlights, financial performance, and strategies
  • Key companies covered as a part of this study include Sanofi Pasteur SA, Janssen, Pfizer Inc., BIOCRYST PHARMACEUTICALS, INC., Tychan Pte. Ltd., Johnson & Johnson Services, Inc., Takeda Pharmaceutical Company Limited, Bayer AG, GlaxoSmithKline plc, Bio-Manguinhos, Institut Pasteur de Dakar, and FSUE Chumakov
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
  • The global yellow fever treatment market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global yellow fever treatment market

Detailed Segmentation:

  • Global Yellow Fever Treatment Market, By Transmission Type:
    • Sylvatic Yellow Fever
    • Intermediate Yellow Fever
    • Urban Yellow Fever
  • Global Yellow Fever Treatment Market, By Treatment Type:
    • Vaccines
    • Medications
    • Others
  • Global Yellow Fever Treatment Market, By Application:
    • Hospitals
    • Clinics
    • Community Health Centres
    • Others
  • Global Yellow Fever Treatment Market, By Region:
    • North America
      • Transmission Type
        • Sylvatic Yellow Fever
        • Intermediate Yellow Fever
        • Urban Yellow Fever
      • Treatment Type
        • Vaccines
        • Medications
        • Others
      • Application
        • Hospitals
        • Clinics
        • Community Health Centers
        • Others
      • By Country
        • U.S.
        • Canada
    • Latin America
      • Transmission Type
        • Sylvatic Yellow Fever
        • Intermediate Yellow Fever
        • Urban Yellow Fever
      • Treatment Type
        • Vaccines
        • Medications
        • Others
      • Application
        • Hospitals
        • Clinics
        • Community Health Centers
        • Others
      • By Country
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Transmission Type
        • Sylvatic Yellow Fever
        • Intermediate Yellow Fever
        • Urban Yellow Fever
      • Treatment Type
        • Vaccines
        • Medications
        • Others
      • Application
        • Hospitals
        • Clinics
        • Community Health Centers
        • Others
      • By Country
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Transmission Type
        • Sylvatic Yellow Fever
        • Intermediate Yellow Fever
        • Urban Yellow Fever
      • Treatment Type
        • Vaccines
        • Medications
        • Others
      • Application
        • Hospitals
        • Clinics
        • Community Health Centers
        • Others
      • By Country
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • Transmission Type
        • Sylvatic Yellow Fever
        • Intermediate Yellow Fever
        • Urban Yellow Fever
      • Treatment Type
        • Vaccines
        • Medications
        • Others
      • Application
        • Hospitals
        • Clinics
        • Community Health Centers
        • Others
      • By Country
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Transmission Type
        • Sylvatic Yellow Fever
        • Intermediate Yellow Fever
        • Urban Yellow Fever
      • Treatment Type
        • Vaccines
        • Medications
        • Others
      • Application
        • Hospitals
        • Clinics
        • Community Health Centers
        • Others
      • By Country/Region
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Sanofi Pasteur SA*
      • Company Highlights
      • Products Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • Janssen
    • Pfizer Inc.
    • BIOCRYST PHARMACEUTICALS, INC.
    • Tychan Pte. Ltd.
    • Johnson & Johnson Services, Inc.
    • Takeda Pharmaceutical Company Limited
    • Bayer AG
    • GlaxoSmithKline plc
    • Bio-Manguinhos
    • Institut Pasteur de Dakar
    • FSUE Chumakov

 “*” marked represents similar segmentation in other categories in the respective section.

Frequently Asked Questions

The global yellow fever treatment market size is estimated to be valued at US$ 470.5 million in 2021 and is expected to exhibit a CAGR of 3.7% between 2021 and 2028.
Factors such as increasing prevalence of yellow fever and increasing research and development activities are expected to drive the growth of the market during the forecast period.
Hospital is the leading application segment and is expected to hold a major market share during the forecast period.
The major factors hampering the growth of the market include limited treatment options and severity associated with taking wrong medications due to misdiagnosis or incorrect self-diagnosis.
Major players operating in the market include Sanofi Pasteur SA, Janssen, Pfizer Inc., BIOCRYST PHARMACEUTICALS, INC., Tychan Pte. Ltd., Johnson & Johnson Services, Inc., Takeda Pharmaceutical Company Limited, Bayer AG, GlaxoSmithKline plc, Bio-Manguinhos, Institut Pasteur de Dakar, and FSUE Chumakov.

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