The Global Anti-epileptic Drugs for Pediatrics Market by drug type (1st generation, 2nd generation, and 3rd generation) and region (North America, Latin America, Europe, Asia-Pacific, the Middle East and Africa) was valued at US$ 671.9 million in 2016 and is projected to exhibit a CAGR of 7.9% over the forecast period (2017–2025), as highlighted in a new report published by Coherent Market Insights. Growing incidence of epilepsy and associated co-morbidities are expected to be the major factors driving growth of the global anti-epileptic drugs for pediatrics market over the foreseeable future.
Manufacturers are focusing on upgrading the available treatment options as well as developing new solutions for chronic as well as refractory epilepsies. Improving the therapeutic efficacy and effectiveness while lowering the side effects and interactions for better effects in adjunctive therapies is the epicenter of research and development for new treatment options in terms of drugs. For instance, Pfizer, Inc. entered into partnership with Epilepsy Foundation to find solutions for generic forms of epilepsy and associated neurological disorders also, in 2016, Pfizer, Inc.’s Lyrica (pregabalin) cleared phase-3 clinical trials for prescription to pediatric patients. Furthermore, UCB Pharma Limited received the U.S. FDA-approval for Briviact, for the treatment of patients with partial onset seizures.
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Manufacturers are also working on existing issues associated with epilepsy treatment for children, through research and development activities of pipeline products and by exploring the effectiveness of generic drugs as compared to branded products. In 2017, second trial in the FDA-sponsored EQUIGEN project confirmed that generic versions of lamotrigine appear bioequivalent to Lamictal, the brand-name form of the drug. Furthermore, Sunovion announced the submission of a supplemental New Drug Application (sNDA) to the Food and Drug Administration (FDA) for the use of Aptiom (eslicarbazepine acetate) as monotherapy or adjunctive therapy for the treatment of partial-onset seizures (POS) for children 4 years of age or below. Pfizer, Inc. has molecules NCT02072824, NCT01463306, and NCT01747915 in the pipeline indicated for epilepsy. Epygenix Therapeutics, Inc., in 2017, announced the U.S. FDA approval for orphan drug designation to EPX-100 and EPX-200 for treatment of patients with Dravet syndrome, which is a catastrophic form of epilepsy.
Key Takeaways of the Anti-epileptic Drugs for Pediatrics Market:
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