Anti-epileptic Drugs for Pediatrics Market– Insights
Epilepsy is associated with disrupted activities in the brain called seizures, which affects the central nervous system. Depending on the area of the brain obstructed by seizures, these are categorized into generalized seizures and partial seizures. Generalized seizures affect the whole brain, while partial seizures affect just one part of the brain. Depending on their severity, seizures are termed as mild seizures and stronger seizures. Mild seizures are difficult to diagnose, as these last for only a few seconds. Stronger seizures may last for a few seconds to several minutes, resulting in spasms and uncontrollable muscle twitches. This may cause the patient to lose consciousness, and experience temporary loss of cognition, or memory loss.
Pediatric epilepsy can be caused due to a trauma injury, complications during birth, or genetic disorder. Epilepsy that occurs due to brain infections such as meningitis is known as symptomatic epilepsy, while a genetics related condition is called idiopathic epilepsy.
The global anti-epileptic drugs for pediatrics market is estimated to be US$ 918.9 million in 2019, and is expected to witness a CAGR of 7.5% over the forecast period (2019 – 2027).
Global Anti-epileptic Drugs for Pediatrics Market Share (%) Analysis, By Drug Type, 2019
Source: Coherent Market Insights Analysis (2020)
Newer drug therapies with symptom specific indications are expected to boost market growth
Epilepsy is a highly prevalent disorder, and an estimated 50 million people worldwide are suffering from epilepsy, out of which almost 80% live in emerging economies as per the World Health Organization (WHO) 2019. According to the American Academy of Pediatrics, as of April 2017, epilepsy was estimated to affect 0.5% to 1% of children globally and is the most prevalent chronic condition of the central nervous system among children. According to Epilepsy Foundation, each year, around 150,000 new cases of epilepsy are reported in the U.S. and the rate of occurrence is high among young children and geriatric population. Furthermore, in 2015, the Society of Neuroscience stated that epilepsy affected around 10.5 million children worldwide, and the type and severity of the disorder varies significantly.
The incidence and prevalence of epilepsy in children appears to be lower in developed economies and highest in rural areas of emerging economies. This is mainly attributed to the presence of FDA-approved anti-epileptic drugs in developed economies and vast distribution channels ensuring higher accessibility to treatments. Scientific and technological advancements have led to the introduction of several medications in the past decade, which are used in combination in a personalized way by physicians for the treatment of pediatrics. Drugs approved by the U.S. Food & Drug Administration (FDA) include Phenytoin (Dilantin), Carbamazepine (Carbatrol), Divalproex Sodium (Depakote), and Ethosuximide (Zarontin).
Global Anti-epileptic Drugs for Pediatrics Market - Restraints
However, lack of awareness regarding epilepsy and non-availability of medical facilities in poor and developing countries are some of the factors that are expected to hinder growth of the anti-epileptic drugs for pediatrics market.
Global Anti-epileptic Drugs for Pediatrics Market - Regional Insights
On the basis of region, the global anti-epileptic drugs for pediatrics market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America holds a dominant position in the global anti-epileptic drugs for pediatrics market owing to increasing number of regulatory approval for drugs. For instance, in 2018, Eisai Inc. received U.S. Food and Drug Administration (FDA) approval for its antiepileptic drug, FYCOMPA (perampanel) CIII, for monotherapy and adjunctive use in pediatric patients 4 years and older for the treatment of partial-onset seizures (POS) with or without secondarily generalized seizures.
Asia Pacific is the fastest growing region in the global anti-epileptic drugs for pediatrics market owing to increasing product launches. For instance, in 2019, GlaxoSmithKline plc. launched dispersible tablet formulation of Lamictal (lamotrigine dispersible tablet) for the treatment of epilepsy in China for pediatric patients.
Global Anti-epileptic Drugs for Pediatrics Market Value (US$ Mn) & Y-o-Y Growth (%), 2016-2027
Source: Coherent Market Insights Analysis (2020)
Global Anti-epileptic Drugs for Pediatrics Market Competitive Landscape
Key players operating in the global Anti-epileptic Drugs for Pediatrics market include Mylan N.V., Cephalon, Inc., GlaxoSmithKline plc, Janssen Pharmaceuticals, Novartis AG, Pfizer, Inc., Sanofi S.A., UCB Pharma Limited, Sunovion Pharmaceuticals Limited, Valeant Pharmaceuticals International, Inc., Zynerba, Zogenix, and Insys Therapeutics.