Significant Number of B-cell Maturation Antigen (BCMA) Targeted Therapies in Pipeline is Expected to Boost Market Growth

Published On : Oct 20, 2017

The Global B-cell Maturation Antigen (BCMA) Targeted Therapies Market, by product type (CAR-T cell, bispecific antibodies, and antibody drug conjugates), and by indication (acute lymphoblastic leukemia, and multiple myeloma) has potential products in pipeline, as highlighted in a new report published by Coherent Market Insights. Increasing number of BCMA targeted therapies in pipeline and increasing prevalence of multiple myeloma are expected to favor growth of the B-cell maturation antigen (BCMA) targeted therapies market worldwide.

Increasing recurrence of multiple myeloma has been a major obstacle.  According to the National Cancer Institute, in 2016, around 75,000 patients globally were recorded to be suffering from relapsed or refractory multiple myeloma, with a relative survival rate of 5 years. According to American Cancer Society, as of 2017, around 30,280 multiple myeloma cases are estimated to be diagnosed, out of which around 12,590 deaths are estimated to occur. Multiple myeloma (MM) is the second most common hematological malignancy in the U.S. and European countries. According to American Cancer Society, in the U.S. the lifetime risk of contracting multiple myeloma is 1 in 143 (0.7%). B-cell maturation antigen (BCMA), is a cell surface protein that is expressed on the malignant plasma cells. This cell surface protein has emerged as a very selective antigen to be targeted for the treatment of multiple myeloma. B-cell maturation antigen possess co-immunoprecipitation property with a master transcription factor (IRF-4) are mediated for myeloma cell survival. This suggests the potential effect of BCMA in oncogenesis, making it a choice of preference for multiple myeloma treatment. Thus, rise in number of multiple myeloma cases and development of novel BCMA therapy for the treatment of multiple myeloma provides lucrative opportunities for the market players. Adoption of BCMA targeted therapies is expected increase, as patients undergoing chemotherapy and radiation therapy are prone to recurrence of cancer.

Browse through 130 Pages and an in-depth TOC on ‘B-cell Maturation Antigen (BCMA) Targeted Therapies, by Product type (Antibody Drug Conjugates, CAR-T Cells, and Bispecific Antibodies), by Indication (Acute Lymphoblastic Leukemia and Multiple Myeloma), and by Region

To know the latest trends and insights prevalent in the B-cell maturation antigen (BCMA) targeted therapies market, click the link below:

https://www.coherentmarketinsights.com/market-insight/bcma-targeted-therapies-market-190

According to the Cancer Research U.K., as of 2014, myeloma is estimated to be the 18th most common cancer in the U.K., with an estimated 5,500 new cases of multiple myeloma, reported around 15 new cases every day. Incidence rates for myeloma are projected to rise by 11% or 12 cases per 100,000 people by 2035. According to the National Center for Biotechnology Information, 2014, multiple myeloma represents 8.2% of all blood cancers in Africa.

Market players are actively investing in research and development of novel multiple myeloma therapies to develop alternatives for existing drugs. These therapies include chimeric antigen receptor T cells, antibody-drug conjugate, and bispecific antibodies. Preclinical and clinical trial results on these therapies have demonstrated potential benefits. Key player such as Glaxosmithkline Plc. is developing an antibody drug conjugate for the treatment of relapsed/refractory multiple myeloma and other advanced hematologic malignancies expressing BCMA, whereas Bluebird Bio, Inc. is actively developing an anti-BCMA CAR-T cell drug product to treat relapsed and/or refractory multiple myeloma. Boehringer Ingelheim GmbH is performing clinical trials for relapsed and/or refractory multiple myeloma patients using bispecific antibody.

Key Takeaways of the Market:

  • According to the American Society of Clinical Oncology (ASCO), in 2016, multiple myeloma was the second most common blood cancer, after non-Hodgkin lymphoma, accounting for 1% of all kinds of malignancies globally, with 70 years being the median age of diagnosis
  • As there are no treatment option available for patients with recurrent cancer, development of therapy to treat relapsed and/or refractory multiple myeloma is expected to provide market players with lucrative opportunities
  • Some of the major players involved in the development of B-cell maturation antigen (BCMA) targeted therapies market are Celgene Corporation, GlaxoSmithKline plc, Novartis AG, Juno Therapeutics, Gilead Sciences. Inc., Amgen Inc., Affimed N.V, Poseida Therapeutics, Inc., and Autolus Ltd.

About Coherent Market Insights:

Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.

Contact Us:

Mr. Shah
Coherent Market Insights
1001 4th Ave, 
#3200 
Seattle, WA 98154
Tel: +1-206-701-6702
Email: [email protected]

"How Can I Help You" ?

Finding it difficult to find the research that would cater to your business demands? Give us a chance to help you. One of our Research Consultants will connect to provide a customized solution.

Coherent Market Insights Benefits

  • Custom Research Solution

    Talk to our research consultant to design an exclusive report as per your research needs.

  • Customer Fulfilment

    We aim to fulfil client's research demands with tailored research solutions.

  • Quick Turnaround Time Reports

    We aim to provide research studies in quickest turnaround time and in a much cost effective manner.

  • 360-degree Approach

    We cover each industry from supply and demand side with an aim to provide a most holistic research study.

  • Assured Quality

    We strive to provide most accurate and reliable research findings in our research reports.