CORNEAL TRANSPLANT MARKET SIZE AND SHARE ANALYSIS - GROWTH TRENDS AND FORECASTS (2025-2032)

Global Corneal Transplant Market Size and Forecast – 2025 to 2032

The Global Corneal Transplant Market is estimated to be valued at USD 469.9 million in 2025 and is expected to reach USD 711.3 million by 2032, exhibiting a compound annual growth rate (CAGR) of 6.1% from 2025 to 2032.

Key Takeaways of the global corneal transplant market:

• In 2025, Penetrating Keratoplasty (PK) is projected to account for the largest market share of 39.2% by procedure type.
• Fuchs' Endothelial Dystrophy is expected to lead by indication with a 53.6% share in 2025.
• Autografts segment is projected to dominate the market by donor type with a 53.3% share in 2025.
• North America is expected to lead the market, holding a share of 40.3% in 2025. Asia Pacific is anticipated to be the fastest-growing region, with a market share of 29.8% in 2025.

Market Overview:

The corneal transplant market is experiencing significant growth due to the increasing prevalence of corneal disorders, advancements in surgical techniques, and rising awareness about eye donation. Additionally, the growing geriatric population, which is more susceptible to corneal diseases, is driving the demand for corneal transplants. Furthermore, government initiatives and funding to promote eye donation and transplantation are expected to fuel the market growth in the coming years.

Currents Events and Its Impact

Uncover macros and micros vetted on 75+ parameters: Get instant access to report

Segmental Analysis

To learn more about this report, Request sample copy

Corneal Transplant Market Insights, By Procedure Type - Penetrating Keratoplasty (PK): Dominant due to full-thickness replacement capability and high success rates

In terms of Procedure Type, Penetrating Keratoplasty (PK) segment is expected to hold the highest market share of 39.2% in 2025, owing to its long-standing history as the most widely performed corneal transplantation technique. PK involves the replacement of the full thickness of the cornea, making it suitable for treating a wide range of corneal disorders, including advanced keratoconus, corneal scarring, and corneal dystrophies.

The high success rate and long-term stability of visual outcomes associated with PK have contributed to its dominant market position. Advancements in surgical techniques, such as the use of femtosecond lasers for precise incisions and the development of newer suture materials, have further enhanced the outcomes and reduced complications associated with penetrating keratoplasty.

Corneal Transplant Market Insights, By Indication- Fuchs' Endothelial Dystrophy: Dominant due to high prevalence in aging populations.

In terms of Indication, Fuchs' Endothelial Dystrophy segment is projected to account for the highest market share of 23.6% in 2025. Fuchs' dystrophy is a progressive disorder characterized by the deterioration of the corneal endothelium, leading to corneal edema, visual impairment, and ultimately, the need for corneal transplantation.

The increasing prevalence of Fuchs' dystrophy, particularly among the aging population, has been a major driver for the segment growth. As life expectancy increases, a greater number of individuals are at risk of developing Fuchs' dystrophy, leading to a higher demand for corneal transplantation procedures.

Advancements in diagnostic techniques, such as specular microscopy devices and anterior segment optical coherence tomography (AS-OCT), have enabled the early detection and monitoring of Fuchs' dystrophy. This has allowed for timely intervention and better management of the condition, further contributing to the segment growth.

Corneal Transplant Market Insights, By Donor Type - Autograft: Dominant due to elimination of rejection risk and no need for immunosuppression.

In terms of Donor Type, Autograft segment is projected to contribute the highest market share of 53.3% in 2025. Autograft refers to the use of the patient's own tissue for corneal transplantation, typically obtained from the contralateral healthy eye. This approach eliminates the risk of immune rejection and the need for long-term immunosuppression, making it an attractive option for both patients and surgeons.

The growing prevalence of unilateral corneal disorders, such as corneal scars secondary to trauma or infection, has been a significant driver for the autograft segment growth. In such cases, the healthy eye can serve as a source of donor tissue, providing a viable alternative to allograft or organ transplantation.

Role of Artificial Intelligence (AI) in the Global Corneal Transplant Market

Artificial Intelligence (AI) is revolutionizing the global corneal transplant market by enhancing diagnostic precision, personalising surgical planning, and optimizing donor-recipient matching processes. Through AI-driven imaging technologies such as deep learning algorithms applied to Anterior Segment Optical Coherence Tomography (AS-OCT), ophthalmologists can now detect corneal abnormalities with high accuracy and determine eligibility for procedures like Descemet Membrane Endothelial Keratoplasty (DMEK) or Deep Anterior Lamellar Keratoplasty (DALK). Additionally, AI enables predictive analytics to forecast graft success rates and postoperative complications, thereby improving clinical outcomes and reducing healthcare costs. Automation in patient triage, donor tissue evaluation, and digital health platforms is further streamlining workflows and minimizing human error. These innovations contribute to higher surgical efficiency and accessibility in regions with limited ophthalmic infrastructure.

An exemplary case is iOR Partners, a U.S.-based company specializing in ophthalmic surgical care and Ambulatory Surgery Center (ASC) solutions. iOR Partners integrates Artificial Intelligence (AI) into its surgical management platform to support ophthalmologists working in outpatient surgical settings. Their technology leverages AI algorithms to analyze surgical performance data, predict outcomes, and suggest procedural enhancements—leading to improved efficiency, reduced surgical complications, and higher patient satisfaction. As AI continues to enable new business models, such as remote surgical guidance and real-time decision support, the corneal transplant market is positioned for accelerated growth. However, to ensure responsible adoption, the sector must address challenges including data privacy, algorithmic transparency, and equitable access to AI-powered tools.

Regional Insights:

To learn more about this report, Request sample copy

North America Corneal Transplant Market Analysis and Trends

North America’s dominance in the global corneal transplant market with an estimated share of 40.3% in 2025 can be attributed to several factors. The region boasts a well-established healthcare infrastructure, advanced medical technologies, and a high adoption rate of innovative surgical procedures. The presence of leading pharmaceutical and medical device companies, such as Bausch & Lomb, Alcon, and Johnson & Johnson, further contributes to the market's growth. These companies actively invest in research and development, driving product innovation and expanding their market presence. Moreover, favorable reimbursement policies and increasing awareness about corneal diseases and treatment options have fueled the demand for corneal transplants in the region.

In April 2024, according to the Rise of Hospital Infrastructure & Modernization Updates, the U.S. healthcare system comprises over 6,000 hospitals and thousands of clinics, offering more than a million hospital beds. The country’s infrastructure includes advanced research labs, modern medical equipment, and cutting-edge technology. Federal funding continues to support the modernization of healthcare facilities.

Asia Pacific Corneal Transplant Market Analysis and Trends

The Asia Pacific exhibits the fastest growth in the global corneal transplant market with a projected share of 29.8% in 2025. The region's rapid economic development, improving healthcare infrastructure, and increasing healthcare expenditure have created a conducive environment for the market growth. Countries like China and India, with their large populations and rising incidence of corneal disorders, present significant growth opportunities. The increasing availability of skilled healthcare professionals and the establishment of specialized eye care centers have further boosted the market's expansion. Additionally, government initiatives aimed at improving access to healthcare services and increasing awareness about eye donation have positively impacted the market growth in the Asia Pacific region.

Global Corneal Transplant Market Outlook for Key Countries:

U.S. Corneal Transplant Market Trends

The U.S. corneal transplant market is witnessing steady growth driven by rising cases of corneal disorders, advancements in minimally invasive procedures like Descemet Membrane Endothelial Keratoplasty (DMEK) and Descemet Stripping Automated Endothelial Keratoplasty (DSAEK), and increasing public awareness about eye donation. Technological innovations, such as artificial corneas and enhanced imaging tools, are improving surgical outcomes. However, a persistent shortage of donor tissues remains a key challenge, prompting ongoing efforts in donation advocacy and eye banking initiatives. For instance, in February 2025, Glaukos Corporation, a company specializing in innovative treatments for glaucoma, corneal, and retinal disorders, announced that the U.S. FDA had issued a “Day 74” letter for its New Drug Application (NDA) for Epioxa (Epi-on), a next-gen corneal cross-linking therapy for keratoconus.

China Corneal Transplant Market Trends

China's market for corneal transplants is experiencing significant growth due to the country's large population, increasing healthcare awareness, and rising disposable incomes. The government's initiatives to improve healthcare infrastructure and expand access to medical services have created a favorable environment for market growth. Local companies, such as Eyebright Medical Technology and Yingke Biotechnology, are making significant contributions to the market by developing innovative products and technologies tailored to the specific needs of the Chinese population. For example, in January 2023, Union Hospital in Wuhan, affiliated with Tongji Medical College at Huazhong University of Science and Technology, successfully performed its first artificial cornea transplant on a 25-year-old woman. Such advancements are anticipated to contribute significantly to the country’s market growth.

India Corneal Transplant Market Trends

India continues to be a key player in the global corneal transplant market, driven by a high burden of corneal blindness and a growing demand for corneal transplantation procedures. The country has a vast network of eye banks and a skilled pool of ophthalmologists, contributing to the market's growth. Organizations like the L V Prasad Eye Institute and the Aravind Eye Care System have played a crucial role in advancing corneal transplantation techniques and increasing access to care in India. For instance, in August 2024, MY Hospital, a leading government healthcare institution in Madhya Pradesh, India, launched Eye Donation Fortnight to address the severe shortage of corneal donors in India, the initiative aims to raise awareness and dispel myths around eye donation.

Malta Corneal Transplant Market Trends

Malta's corneal transplant market, though modest in scale, is progressively evolving in response to the increasing prevalence of corneal diseases such as keratoconus and Fuchs' dystrophy. The nation's healthcare infrastructure is adapting to meet these challenges, with a focus on enhancing surgical capabilities and expanding access to advanced ophthalmic procedures. However, Malta faces a significant hurdle in the form of limited availability of donor corneal tissues, a challenge common to many countries worldwide. For instance, in October 2024, St Thomas Hospital, a leading healthcare provider in Malta, launched its new Eye Clinic in Qormi, introducing innovative Descemet Membrane Endothelial Keratoplasty DMEK and Deep Anterior Lamellar Keratoplasty, DALK corneal transplant techniques.

Market Players, Key Developments, and Competitive Intelligence:

To learn more about this report, Request sample copy

Key Developments:

• In March 2025, Indian Council of Medical Research ICMR, in partnership with AIIMS New Delhi and Dr. Shroff’s Charity Eye Hospital, successfully tested drone transport of human corneas under the i-DRONE initiative. The drone cut delivery time from 2.5 hours to 40 minutes between Sonipat and AIIMS Jhajjar, enabling a successful transplant and showcasing a breakthrough in medical logistics.
• In March 2025, Massachusetts Eye and Ear, part of the Mass General Brigham network, developed a breakthrough stem cell treatment—CALEC—that successfully repaired corneal damage in a clinical trial. The procedure uses stem cells from a patient’s healthy eye to restore the damaged one. In a Phase 1/2 trial published in Nature Communications, 14 patients were treated with over 90% showing full or partial corneal surface restoration after 18 months.
• In November 2024, The University Hospitals of North Midlands NHS Trust (UHNM) launched a new eye and tissue donation service at Royal Stoke University Hospital, becoming one of just ten NHS trusts commissioned by NHS Blood and Transplant to run its own in-house program. The initiative, called iORbIT, includes UHNM’s first dedicated nurse for eye donation and aims to collect over 350 donations annually.
• In June 2024, CorneaGen, a leading U.S.-based provider of ocular tissue and corneal innovations, launched CTAK (Corneal Tissue Addition for Keratoplasty)—a groundbreaking solution for keratoconus treatment. Developed in collaboration with CTAK LLC and Ziemer, CTAK uses sterile, gamma-irradiated corneal tissue segments tailored to individual patient needs.

Top Strategies Followed by Global Corneal Transplant Market Players

• Established players in the global corneal transplant market are focusing on extensive research and development to innovate high-performance products. The focus is on enhancing clinical outcomes through advanced, high-performance solutions. These efforts aim to address key challenges such as donor tissue shortages and post-surgical complications, while also improving the precision and success rates of procedures.
  • For instance, in June 2023, Pandorum Technologies, a biotech firm, in collaboration with Dr. Shroff’s Charity Eye Hospital, Eye care center in Delhi, India, announced that it is set to begin human trials for India’s first 'liquid cornea'—a breakthrough treatment for corneal blindness. This homegrown innovation aims to restore sight for millions, marking a major milestone in Indian ophthalmic science.

• Mid-level players in the market are concentrating on delivering cost-effective solutions to target price-sensitive consumers. By optimizing manufacturing processes and leveraging economies of scale, these companies offer quality corneal transplant products at competitive prices. This strategy enables them to capture a significant market share and cater to the needs of healthcare providers and patients with budget constraints.
  • For instance, on May 15, 2025, Mustapha Pacha University Hospital, a leading medical institution in Algeria, spearheaded Algeria’s first national corneal transplant program using grafts from deceased donors. Announced by Professor Rachid Belhadj, Director of Medical and Paramedical Activities, the initiative aims to restore vision through ethically sourced corneal grafts.

• Small-scale players in the industry often focus on niche specialization to differentiate themselves from larger competitors. By targeting specific market segments with unique features or innovative products, these companies carve out a profitable niche.
  • In January 2022, Beijing Microkpro Medical Instrument Co. Ltd., a China-based innovator in ophthalmic devices, received National Medical Products Administration, (NMPA) approval for its Miok Keratoprothesis, the world’s first artificial cornea made entirely from non-biological materials, eliminating the need for donor tissue.

Market Report Scope

Corneal Transplant Market Dynamics

To learn more about this report, Request sample copy

Corneal Transplant Market Driver - Increasing Prevalence of Eye Disorders

The global corneal transplant market is witnessing significant growth, primarily driven by the increasing prevalence of various eye disorders worldwide. Eye conditions such as keratoconus, Fuchs' dystrophy, corneal ulcers, and corneal scarring are becoming more common, leading to a higher demand for corneal transplant procedures. Factors such as aging populations, changing lifestyles, and environmental factors contribute to the rising incidence of these disorders. As more people are diagnosed with corneal conditions that require transplantation, the market for corneal transplant procedures and related products is expected to expand.

Moreover, advancements in surgical techniques and postoperative care have improved the success rates and outcomes of corneal transplants, further boosted patient confidence and driven market growth. As awareness about the availability and benefits of corneal transplants spreads, coupled with the increasing prevalence of eye disorders, the global corneal transplant market is poised for significant growth in the coming years. For instance, in May 2024, the World Health Organization (WHO), the United Nations’ specialized agency for global health, launched the SPECS 2030 initiative to address uncorrected refractive errors—the leading cause of vision impairment worldwide.

Corneal Transplant Market Opportunity: Rising Awareness About Eye Donation

Increasing awareness about eye donation presents a promising opportunity for the growth of the global corneal transplant market. Governments, non-profit organizations, and healthcare institutions worldwide are actively promoting the importance of eye donation and its potential to restore sight for those suffering from corneal blindness. Through various campaigns, educational programs, and community outreach initiatives, the public is being educated about the life-changing impact of corneal transplantation and the critical role of eye donation in making this treatment possible. As a result, there has been a gradual rise in the number of people pledging to donate their eyes after death, leading to an increased availability of donor corneas. This rising awareness and willingness to donate eyes are expected to alleviate the shortage of donor tissue, which has been a long-standing challenge in the corneal transplant market.

Consequently, the growing pool of potential donors is likely to boost the market's growth by improving access to corneal transplantation and reducing waiting times for patients in need. For instance, in September 2024, AIIMS Raipur, a top government medical institute, celebrated National Eye Donation Fortnight with the theme “I Can See Clearly Now.” The event included a skit, awareness talks, and a radio programme to help people understand the importance of eye donation and encourage them to pledge their eyes to help others see again.

Analyst Opinion (Expert Opinion)

• The global corneal transplant market is experiencing robust growth driven by advancements in surgical techniques such as Descemet Membrane Endothelial Keratoplasty (DMEK) and Deep Anterior Lamellar Keratoplasty (DALK), which offer faster recovery and lower rejection rates. Increasing prevalence of corneal disorders, growing elderly population, supportive regulatory pathways for ophthalmic procedures, and rising awareness through eye donation campaigns are further fueling demand. However, limited access to donor tissues in low- and middle-income countries, along with logistical and reimbursement challenges, continue to restrain the market expansion. Opportunities lie in the growing adoption of artificial corneas and bioengineered grafts, as well as the emergence of robotic and AI-assisted surgical platforms that promise to improve procedural accuracy and outcomes.
• Recent conferences such as the World Cornea Congress (WCC), ARVO Annual Meeting, and European Society of Cataract and Refractive Surgeons (ESCRS) have played a pivotal role in advancing sector knowledge by showcasing innovations, sharing clinical outcomes, and shaping future research directions. Notable initiatives include SightLife’s global partnerships to enhance corneal tissue access and the U.S. FDA’s support for regenerative eye therapies. In India, the National Eye Bank Network initiative aims to streamline cornea collection and transplantation, setting a precedent for similar efforts in other developing regions.

Market Segmentation

•  Procedure Type Insights (Revenue, USD Mn, 2020 - 2032)
• • Penetrating Keratoplasty (PK)
  • Descemet Membrane Endothelial Keratoplasty (DMEK)
  • Descemet Stripping Endothelial Keratoplasty (DSEK)
  • Anterior Lamellar Keratoplasty (ALK)
  • Corneal Limbal Stem Cell Transplant
  • Others (Artificial Cornea Transplant etc.)
•  Indication Insights (Revenue, USD Mn, 2020 - 2032)
• • Fuchs' Endothelial Dystrophy
  • Infectious Keratitis
  • Bullous Keratopathy
  • Keratoconus
  • Corneal Scarring
  • Corneal Ulcers
  • Others
•  Donor Type Insights (Revenue, USD Mn, 2020 - 2032)
• • Autograft
  • Allograft
•  Gender Insights (Revenue, USD Mn, 2020 - 2032)
• • Male
  • Female
•  Age Group Insights (Revenue, USD Mn, 2020 - 2032)
• • Pediatric
  • Adult
  • Geriatric
•  End User Insights (Revenue, USD Mn, 2020 - 2032)
• • Hospitals
  • Eye Clinics
  • Ambulatory Surgical Centers
  • Academic & Research Institutes
  • Others
• Regional Insights (Revenue, USD Mn, 2020 - 2032)
  • North America
    • U.S.
    • Canada
  • Latin America
    • Brazil
    • Argentina
    • Mexico
    • Rest of Latin America
  • Europe
    • Germany
    • U.K.
    • Spain
    • France
    • Italy
    • Russia
    • Rest of Europe
  • Asia Pacific
    • China
    • India
    • Japan
    • Australia
    • South Korea
    • ASEAN
    • Rest of Asia Pacific
  • Middle East
    • GCC Countries
    • Israel
    • Rest of Middle East
  • Africa
    • South Africa
    • North Africa
    • Central Africa
• Key Players Insights
  • Alcon
  • Bausch + Lomb
  • Abbott Medical Optics
  • Carl Zeiss AG
  • Johnson & Johnson Vision
  • EyeTechCare
  • Avedro
  • FCI Ophthalmics
  • KeraLink International
  • Meditec AG
  • Ocular Therapeutix
  • OptiMedica Corporation
  • Santen Pharmaceutical
  • Synergeyes
  • Ziemer Ophthalmic Systems

Sources

Primary Research Interviews:

• Ophthalmic Surgeons and Corneal Specialists
• Hospital Procurement Officers (specialised in ophthalmology)
• Representatives from Eye Banks
• R&D Heads of biotechnology and medical device companies

Databases:

• World Health Organization (WHO)
• U.S. Food and Drug Administration (FDA)
• European Medicines Agency (EMA)
• National Eye Institute (NEI), USA
• Ministry of Health and Family Welfare (India)

Magazines:

• Ophthalmology Times
• Medical Device + Diagnostic Industry (MD+DI)
• The Ophthalmologist
• Eyewire News

Journals:

• American Journal of Ophthalmology
• British Journal of Ophthalmology
• Journal of Cataract and Refractive Surgery
• Ophthalmology (AAO Journal)

Newspapers:

• The New York Times – Health
• The Guardian – Science & Health
• The Hindu – Health
• The Times of India – Health

Associations:

• Eye Bank Association of America (EBAA)
• International Agency for the Prevention of Blindness (IAPB)
• American Academy of Ophthalmology (AAO)
• Asia Cornea Society (ACS)
• European Society of Cataract and Refractive Surgeons (ESCRS)

Public Domain Sources:

• Global Observatory on Donation and Transplantation (GODT)
• United Nations Population Division
• Open Government Data (OGD) Platform India
• European Commission – Health and Food Safety
• Indian Council of Medical Research (ICMR)
• National Programme for Control of Blindness and Visual Impairment (NPCBVI), India
• National Organ and Tissue Transplant Organization (NOTTO), India

Proprietary Elements:

• CMI Data Analytics Tool: Proprietary analytics tool to analyze real-time market trends, consumer behavior, and technology adoption in market
• Proprietary CMI existing repository of information for last 8 years