Cell and gene therapy plays a major role in modern healthcare, as it provides concepts and techniques that can be used in gene regulation, cell-cell interactions, regenerative capacity, and remodeling.
Global cell and gene therapy market size was valued at US$ 15,580.3 Million in 2022 and is expected to witness a CAGR of 24.7% over the forecast period (2022 – 2030).
Figure 1. Global Cell and Gene Therapy Market Share (%), by Therapy Type, 2022
Increasing prevalence of cardiovascular disease is expected to propel growth of the cell and gene therapy market.
Increasing prevalence of cardiovascular disease is expected to drive growth of the global cell and gene therapy market over the forecast period. For instance, According to the World Health Organization report published in June 2021, an estimated 17.9 million people died from cardiovascular diseases in 2019, representing 32% of all global deaths, out of these deaths, 85% were due to heart attack and stroke globally. Out of the 17 million premature deaths (under the age of 70) due to non-communicable diseases in 2019, 38% were caused by cardiovascular diseases globally.
Moreover, according to the same source, on May 20, 2022, nearly 90% of COPD, Chronic obstructive pulmonary disease caused deaths globally in those under 70 years of age occur in low- and middle-income countries (LMIC) like India and Bangladesh.
Report Coverage | Details | ||
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Base Year: | 2021 | Market Size in 2022: |
US$ 15,580.3 Mn |
Historical Data for: | 2017 to 2020 | Forecast Period: | 2022 to 2030 |
Forecast Period 2022 to 2030 CAGR: | 24.7% | 2030 Value Projection: | US$ 90,984.2 Mn |
Geographies covered: |
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Segments covered: |
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Companies covered: |
Amgen, Biogen, BioMarin Pharmaceuticals, Bristol-Myers Squibb Company, GlaxoSmithKline, Novartis, Pfizer, Regeneron Pharmaceuticals Inc, Spark Therapeutics, Agilis Biotherapeutics, Angionetics AVROBIO, Freeline Therapeutics, Horama, MeiraGTx, Myonexus Therapeutics, Nightstar Therapeutics, Kolon TissueGene, Inc., JCR Pharmaceuticals Co., Ltd., MEDIPOST, and Bluebird Bio. Inc. |
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Growth Drivers: |
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Restraints & Challenges: |
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Figure 2. Global Cell and Gene Therapy Market Share (%), by Region, 2022
Increasing prevalence of neurological disorders in North America is expected to bolster the market growth over the forecast period.
Increasing prevalence of Parkinson Disease is expected to boost demand for global cell and gene therapy market over the forecast period. For instance, according to the Parkinson’s disease Foundation, as of 2022, over 10 million people are suffering from Parkinson’s disease, worldwide. The findings published by the organization demonstrated that incidence rate of Parkinson Disease increases with age and only 4% of people were diagnosed with PD before the age of 50 years. According to the same source, in 2021, the incidence rate of PD in the U.S. was as high as 60,000, annually.
Moreover, according to a study report published by Parkinson’s disease Society of the United Kingdom in 2022, it was estimated that the rate of prevalence of Parkinson’s disease in 2017, was 1-2 people in every 100,000 aged 20-29 and 4 or 5 people in every 100,000 aged 30-39. Prevalence increased with age with the prevalence for those aged 80-84 being 1,696 per 100,000 people which is equivalent to around 1.7% of this age-group in the U.K.
Global Cell and Gene Therapy Market– Impact of Coronavirus (COVID-19) Pandemic
Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe and the World Health Organization had declared it a public health emergency on January 30, 2020.
The sudden outbreak of COVID-19 has bought the world to a standstill. The whole world is fighting this pandemic with increased burden on hospitals and healthcare professionals. In March 2021, according to Blood cancer U.K., a U.K.-based charity organization, conducted a virtual survey in which 47% of respondents reported that their blood cancer appointments and treatment had been impacted in some manner by the pandemic whereas 45% had not been performed due to appointment cancellations or postponement.
Global Cell and Gene Therapy Market: Key Developments
Global Cell and Gene Therapy Market Restraints
Several development challenges such as safety and efficacy issues, lengthy procedures for conducting clinical studies, stringent regulatory framework, and high costs of cell and gene therapy.
Key Players
Key players operating in the global cell and gene therapy market include Amgen, Biogen, BioMarin Pharmaceuticals, Bristol-Myers Squibb Company, GlaxoSmithKline, Novartis, Pfizer, Regeneron Pharmaceuticals Inc, Spark Therapeutics, Agilis Biotherapeutics, Angionetics AVROBIO, Freeline Therapeutics, Horama, MeiraGTx, Myonexus Therapeutics, Nightstar Therapeutics, Kolon TissueGene, Inc., JCR Pharmaceuticals Co., Ltd., MEDIPOST, and Bluebird Bio. Inc.
Cell therapy is the administration of living cells in patients for the treatment of a disease. The source of cell can be autologous or allogeneic, which can be derived from stem cells such as bone marrow. Stem cell therapy is used in bone marrow transplantation. Gene therapy is the introduction, removal, or change in the patient's genetic code for treatment of a disease. Moreover, it modifies the expression of an individual’s genes or repairs abnormal genes. The therapy involves administration of nucleic acid (DNA- Deoxyribo nucleic acid/RNA-Ribo nucleic acid) with carriers called as vectors.
Market Dynamics
Increasing prevalence of cancer cases is a major factor driving the cell and gene therapy market growth. For instance, according to a report by American Cancer Society 2021, the estimated number of new cancer cases diagnosed was 1.9 million and 608,570 cancer deaths in the U.S. Furthermore, for instance, according to the data published by the World Health Organization (WHO) on February 3, 2022, cancer accounted for 10 million deaths in 2020 globally. Furthermore, according to the same source, approximately 400,000 children develop cancer every year from which cervical cancer is the third most common, whereas breast cancer and lung cancer are by far the most common cancers leading to their top position in list of common cancers.
Moreover, increasing number of mergers and acquisitions by key market players drives growth of the global cell and gene therapy market over the forecast period. For instance, in August 2021, Biontech, a biotechnology company, completed acquisition of Gilead Sciences, Inc., a U.S. based biotechnology company, announced the acquisition of the solid tumor neoantigen t-cell receptor (TCR) cell therapy (T-cell receptor (TCR)-based adoptive therapy employs genetically modified lymphocytes that are directed against specific tumor markers) research and development platform and manufacturing facility in Gaithersburg, Maryland. The acquisition will help BioNTech’s cell therapy pipeline by accelerating the individualized solid tumor Neoantigen TCR cell therapy research and development program.
Key features of the study:
Detailed Segmentation:
“*” marked represents similar segmentation in other categories in the respective section.
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