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Cell Cryopreservation Market Analysis & Forecast: 2025-2032

Cell Cryopreservation Market, By Product Type (Cryoprotectant Agents and Equipment), By Application (Stem Cells, Oocytes and Embryotic cells, Sperm Cells, Hepatocytes, Others), By End User (Biopharmaceutical & Pharmaceutical Companies, Research Institutes, Biobank, IVF clinics, Others), By Geography (North America, Latin America, Europe, Asia Pacific, Middle East & Africa)

  • Published In : 16 Sep, 2025
  • Code : CMI1698
  • Pages :192
  • Formats :
      Excel and PDF
  • Industry : Biotechnology
  • Historical Range: 2020 - 2024
  • Forecast Period: 2025 - 2032

Cell Cryopreservation Market Size and Forecast – 2025-2032

Global cell cryopreservation market is estimated to reach at USD 53.64 Bn by 2032 from USD 12.44 Bn in 2025. Sales are likely to reach at a CAGR of 23.2% from 2025 to 2032.

Cell Cryopreservation Market Key Factors

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Key Takeaways

  • By Application, Stem cell segment is projected to account for approximately 30.7% market share in 2025. This is owing to the increasing use of stem cells in regenerative medicine and chronic disease management.
  • Based on Product Type, Equipment segment is anticipated to hold around 60.6% share in the global market in 2025. This is owing to rising demand from research institute and biopharmaceutical sector.
  • By End –User, Biopharmaceutical and Pharmaceutical segment is poised to account for around 40.7% share by 2025. The demand is being driven by extensive research and development activities utilizing cell lines.
  • Regionally, North America is expected to dominate the cell cryopreservation market with over 42.0% share in 2025. Growth is driven by strong investment in biopharmaceutical sector and personalized medicine.

Market Overview

Growing prevalence of chronic diseases coupled with rising investments in R&D of regenerative medicine can drive the global cell cryopreservation market growth.The market is witnessing various innovations that aid in commercialization and uptake of cell cryopreservation technologies. There has been an increased focus on developing techniques that can better preserve cell viability and functionality post-thaw. Cryopreservation of stem cells and genetically modified cells can offer opportunities for applications in drug discovery, personalized medicine and disease modeling over the forecast period.

Current Events and its Impact on the Cell Cryopreservation Market

Current Event

Description and its impact

Integration of AI and Automation in Cryopreservation Protocols

  • Description: Leading companies are integrating artificial intelligence and automation into freezing and thawing systems to improve precision, monitoring, and quality control in cell preservation.
  • Impact: Enhanced consistency and reduced variability in cryopreservation processes, leading to better post-thaw cell viability and scalability of cell-based therapies.

Development of Serum-Free and Chemically Defined Cryopreservation Media

  • Description: Governments and private firms are investing in expanding biobanks and manufacturing hubs for cell and gene therapies, particularly in emerging economies.
  • Impact: Increased demand for advanced cryopreservation solutions, supporting long-term storage and global sample distribution.

Adoption of Blockchain Technology in Biobanking

  • Description: Advanced technologies focusing on non-invasive methods such as light therapy and supplements for symptom relief.
  • Impact: Increased patient comfort and compliance, as these options often carry fewer risks compared to traditional surgeries or invasive procedures.

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Cell Cryopreservation Market Trends

Growing demand for stem cell research

Cell cryopreservation on a global scale is predicted to grow in the upcoming years due to an increase in demand for stem cell research. Stem cells assist in preparing new treatments for numerous chronic and terminal diseases such as cancer, diabetes, heart diseases, and neurodegenerative disorders. One of the most important milestones in stem cell research is the ability to efficiently preserve stem cells through cryopreservation which enables the long-term storage and transport of viable stem cells. The active research being done towards stem cells’ unique capabilities of differentiation and regeneration is anticipated to lead to numerous targets and cell-based therapies.

Investments into advancing stem cell science are not only looked into privately but also publicly. Millions of dollars are allocated by the National Institute of Health in the US towards initiatives focused on stem cells and several biopharma companies and boosting their R&D in stem cell therapies. With the stem cell research advancements, the needs from cell cryopreservation increases to sample volume, infrastructure, and regulatory compliance.

Different types of stem cells require reliable preservation over a stretch for varied applications which range from basic research to clinical translation for advanced medical treatment. For example, for U.S. National Institutes of Health set aside millions to fund stem cell projects. A number of biopharma firms have also increased their research and development efforts targeted at stem cell therapies. Encouraging advancements in stem cell research results in increased requirements for cryopreserved cells in terms of increased sample volumes, infrastructural sophistication, and heightened regulatory compliance.

Researchers require dependable stem cell preservation features so they can store them for long periods, especially for primary research and clinical work. For example, in January 2025, researchers from UC Davis Health plan to conduct further tests on a stem cell therapy to evaluate its effectiveness in treating Crohn’s disease which has shown promising results during preclinical trials.

Advancements in regenerative medicine

Technological advancements in the field of regenerative medicine boost market growth. Regenerative therapies aim to repair or replace damaged cells, tissues and organs through stimulating the body's innate healing response. Some key areas witnessing ground-breaking progress includes tissue engineering, organ engineering and development of artificial organs.

Several clinical trials are exploring the application of tissues grown from cryopreserved cell sources such as skin, bone marrow and heart valves for reconstructive procedures. Emerging field of 3D bioprinting also relies on cryopreserved cell viability for printing transplantable organs and implantable tissues. For example, scientists have successfully 3D printed heart patches, liver tissue and bone structures using living cells.

Cell Cryopreservation Market Opportunities: Rise in adoption of personalized medicine

With the increasing intake and acceptance of personalized medicine, the cell cryopreservation market will inevitably surge. Tailored treatment approaches to specific patients on a molecular level known as Personalized medicine is advanced with these surgical innovations.

The movement toward tailor-made healthcare is especially potent for a patient's retrieval and storage system of cells. Healthcare providers are more likely to make use of a “default” backup which is ready for research at a minute's notice, resulting in significant time savings. A patient whose cells are kept for decades or more will benefit from being able to retain the guards her blood cells and tissue are frozen in. Stem cells from Umbilical Cord blood or Adipose Tissue Stem Cells are excellent for future use as regenerative medicine. These stem cells are eligible to be harvested and corralled in biobanks.

There will be a drastic increase in the availability of personalized medicine accompanied by genomics-based diagnostics and treatment that will drive the demand for cryopreservation services tremendously. This will be from healthcare providers, biobanks and patients themselves who want to store their own cells and bio-samples. According to the World Marrow Donor Association, over 35 million umbilical cord blood units have been cryopreserved globally in public and private biobanks in 2021.

Segment Insights

Cell Cryopreservation Market By Product Type

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By Product Type: Demand for Biopharmaceutical and Research Institutes Boosts Market Growth

The equipment segment is postulated to gain the highest market share of 60.6% in 2025 due to growing demand from biopharmaceutical companies and research institutions. With the evolution in cell-based studies, there is an increased need for advanced techniques of cryopreservation for biological materials transport and storage. There is increasing adoption of ultra-low temperature freezers, liquid nitrogen tanks, and cryogenic vials because of their importance in storing samples.

Responding to these needs, manufacturers are developing highly automated and tailored equipment with features such as precise temperature control, real-time tracking systems, and cloud monitoring tailored for large-scale biobanks and regenerative medicine research centers. Besides aiding in sample transport, these innovations enable global research collaboration by providing precise custodial control and long distance transportation security.

Application Insights: The Rise of Stem Cell Therapies Fuels Market Dominance

The stem cells segment was valued at 30.7% in 2025 and will continue to grow due to increased demand in regenerative medicine and therapeutic research. Stem cells are increasingly utilized for various chronic conditions like leukemia, blood disorders, and cartilage injuries. Umbilical Cord-Derived Stem Cells (UCSCs) have shown clinical promise in treating neurological disorders including, but not limited to, cerebral palsy, autism, and multiple sclerosis.

Advanced technologies in stem cell therapy for complex conditions such as Parkinson’s disease, heart failure, and diabetes are continuously emerging. Active clinical trials for Alzheimer’s disease, some spinal cord injury types, and macular degeneration are increasing the scope of therapeutics. To meet these growing needs, hospitals and bio banks are strengthening their capabilities in the storage and distribution of well-characterized stem cell lines for biobanking. These stem cells are essential for the prospective clinical and drug development landscape, making them a primary application in cryopreservation.

End User Insights: Biopharmaceutical Demand for Cell-Based Research Leads Market Share

Pharmaceutical and biopharmaceutical companies captured the most market share, 40.7%, around 2025 owing to their vast in-house R&D activities. Such companies make extensive use of cryopreserved cells in preclinical testing, efficacy studies, and drug discovery. Following the successful commercialization of cell and gene therapies, there is increased market demand for strong preservation systems to maintain biological sample reproducibility and adhere to regulatory guidelines. Pharma companies are vaulting proprietary and long-term use targeted therapy and biomarker discovery cell line repositories as well.

Regional Analysis

Cell Cryopreservation Market Regional Insights

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North America is projected to maintain the largest share of the cell cryopreservation market, with an anticipated share of 42.0% by 2025. The life sciences market in Canada and The United States have dominantly positioned themselves as leaders owing to the robust healthcare infrastructure, tremendous R&D spending, and benevolent policies. The strength of the region lies in the high biopharmaceutical industry which is heavily dependent on cryopreservation techniques for regenerative medicine, cell based therapies, and cell therapy. Key players such as Thermo Fisher Scientific and BioLife Solutions helps North America retain its position as a leader in innovation sites in cryopreservation solutions.

Asia Pacific is emerging as the fastest growing regional market for cell cryopreservation. The region generated 1,743.7 Million USD in 2023 and is projected to have an estimation of 6,814.9 Million USD by 2030, with a CAGR of 21.5% from 2024 to 2030. Countries such as China, India, Japan, and South Korea are significantly enhancing their life science capabilities. The supporting set of policies from the government like ICMR and DBT which promote Stem cell research along with “Made in China 2025” policy further bolster the estimate for these.

The advancement of bio banking and regenerative medicine is enabling Europe to advance further into the cell cryopreservation market. Germany, United Kingdom, and France are supported by very strong healthcare policies, which also support cell based research and innovation, meaning these countries are leaders in innovation. The European Medicines Agency (EMA) has set severe rules for application of cell therapy procedures which is preserving their integrity and ensuring compliance with cell integrity.

The ath region which includes Saudi Arabia, UAE, and South Africa is slowly starting to grow in the cell cryopreservation market. As of now the market share in this region is lower than other regions, but increasing usage of cryopreservation techniques is encouraging. Investment into modernizing healthcare and adoption of advanced cryopreservation techniques for stem cell banking and regenerative medicine is increasing.

Research indicates that the market is Dominated by the United States, which is expected to lead the market during the projection period. Their well established biotechnology and pharma sector along with strong research and development activities ensures that gap will continue to widen. The presence of key market players also drives demand in the market. As an example in October 2024 Nucleus Biologics announced the launch of their new DMSO free chemically defined cryomedia set NB-KUL DF, a DMSO-free and chemically-defined cryomedia set.

Pricing Analysis – Cell Cryopreservation Market

  • Initial Processing and Freezing
    • Cryoprotective Agents (e.g., DMSO, serum): $10–$50 per sample
    • Laboratory Handling & Cell Processing: $50–$200 per sample
    • Packaging Materials & Cryovials: $2–$10 per vial
    • Total Initial Cost per Sample: $60–$260
  • Storage Costs

            Storage costs are usually calculated per sample, per vial, or by volume (e.g., per mL or per cryovial), and vary by storage duration.

    • Short-Term Storage (1–12 months):
      • -80°C Freezer Storage: $5–$20/month
      • Liquid Nitrogen Vapor Phase Storage: $10–$30/month
    • Long-Term Storage (1+ years):
      • Discounted annual rates available
      • Typical range: $100–$500/year per sample
  • Retrieval and Thawing
    • Retrieval and handling fee: $30–$100
    • Thawing and post-thaw viability testing (optional): $50–$200

End User Feedback – Cell Cryopreservation Market

As technology progresses, users across the market report adopting new features and sharing feedback, which remains optimistic, albeit adaptive over time.

  • IVF or In Vitro Fertilization clinics highlight the greater need for efficiency best practices in cryopreservation for gametes and embryos. They believe that process improvements in freezing junctions and vessels with cryoprotectants are increasingly improving the outcomes of thawed gametes and their ability to achieve pregnancy. In user oriented processes, systems degree of automation and simplicity are very important in busy clinical settings where uniformity is essential.
  • With the inclusion of controlled-rate freezers and chemically defined media into their processes, biotechnology and pharmaceutical companies show increased satisfaction. These instruments aid in maintaining compliance with process and legal regulations in the further development of cell and gene therapy. They also value the growing influence of AI on the optimization of storage and supervision systems.
  • Research and academic institutions prioritize flexibility and low prices. Highly sophisticated and advanced cryopreservation systems are useful, but many institutions would prefer offer mid-level these solutions to address various research requirements.
  • Reliability, traceability and prudent data management are keywords for Biobanks. They appreciate the introduction of blockchain based frameworks, which guarantees the sample's integrity and transparency throughout its life cycle and saves time.

As a whole, respondents remain in a positive net balance, which indicates that most users regard cryopreservation as the basic foundation for the growth of reproductive medicine, personalized therapy and regenerative medicine. Market Report Scope

Market Report Scope

Cell Cryopreservation Market Report Coverage

Report Coverage Details
Base Year: 2024 Market Size in 2025: USD 12.44 Bn
Historical Data for: 2020 To 2024 Forecast Period: 2025 To 2032
Forecast Period 2025 to 2032 CAGR: 23.2% 2032 Value Projection: USD 53.64 Bn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Product Type: Cryoprotectant Agents and Equipment
  • By Application: Stem Cells, Oocytes and Embryotic cells, Sperm Cells, Hepatocytes, Others
  • By End User: Biopharmaceutical & Pharmaceutical Companies, Research Institutes, Biobank , IVF clinics, Others
Companies covered:

Thermo Fisher Scientific Inc., Merck KGaA, GE Healthcare, Lonza Group Ltd., STEMCELL Technologies Inc., BioLife Solutions, Inc., Cryolife, Inc., Organ Recovery Systems Inc., Custom Biogenic Systems, Sartorius AG, Takara Bio Inc., Chart Industries, Inc., Biocision, LLC, Cardinal Health, Inc., Helmer Scientific

Growth Drivers:
  • Growing demand for stem cell research
  • Advancements in regenerative medicine
Restraints & Challenges:
  • High cost of establishment and operations
  • Stringent regulations for stem cell research

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Cell Cryopreservation Market: Key development

  • In February 2025, BioLife Solutions, Inc. expanded its product range to include advanced cryopreservation media and controlled-rate freezers. These additions respond to the ever-increasing demand for cell and gene therapies alongside the preservation and storage of biological materials. The new products are designed to increase the effectiveness and scalability of cryopreservation procedures vital to cell-based therapies.
  • Pluristyx Inc. recently (April 2024) announced the launch of PluriFreeze™, a novel cryopreservation medium tailored for the growth of induced pluripotent stem cells (iPSCs). This advancement is expected to enhance the precision and efficacy of iPSC therapy, bolster regenerative medicine, and propel the growth of personalized medicine. The PluriFreeze™ medium is designed to mitigate the cell damage inflicted during the freezing and thawing stages, critical for the achievement of cell-based therapies.
  • In September 2024, Colder Products Company developed Aseptic micro-connectors, compatible with freeze cassettes for processing in gene and cell therapies. This new design facilitates the junctions to be formed external to the biosafety cabinets enhancing ease of handling biological samples and mitigates wastage during storage and transport. Such advancements are important at all levels of the supply chain to maintain biological material.

Analysts’ Views on Cell Cryopreservation Market

  • Increasing investment in stem cell research drives the global cell cryopreservation market. Moreover, the focus on developing stem cell biobanks stem from the fact these biobanks are used in the treatment of many otherwise incurable diseases. The demand for storage of various cells for future therapy use rises with the increased prevalence of chronic diseases.
  • The costly establishment and maintenance of stem cell banks creates barriers to market growth. Market growth is also hindered by safety concerns regarding the long term storage of viable tissues and stem cells. Varying global regulations on stem cell research can also stall market growth.
  • During the forecast period, North America holds a dominant market share for cell cryopreservation. The region’s investment in research infrastructure and supporting regulations are enabling factors for market advancement.
  • The APAC region is poised to be the fastest growing. Countries like India, Japan, and China are witnessing fast paced growth in their biopharma and biotech industries, increasing the adoption of cell cryopreservation solutions. The growing awareness for storage of stem cord blood, coupled with increased investments in regenerative medicine R&D, can be positioned as lucrative opportunities for market players.

Market Segmentation

  • By Product Type
    • Cryoprotectant Agents
      • Glycerol
      • Dimethyl Sulfoxide (DMSO)
      • Others
    • Equipment
      •  Incubators
      • Liquid Nitrogen Supply Tanks
      • Freezers
      • Others
  • By Application
    • Stem Cells
    • Oocytes and Embryotic cells
    • Sperm Cells
    • Hepatocytes
    • Others 
  •  By End User
    • Biopharmaceutical & Pharmaceutical Companies
    • Research Institutes
    • Biobanks
    • IVF clinics
    • Others
  • By Region     
    • North America
      • U.S.
      • Canada
    • Latin America
      • Brazil
      • Argentina
      • Mexico
      • Rest of Latin America
    • Europe
      • Germany
      • U.K.
      • Spain
      • France
      • Italy
      • Russia
      • Rest of Europe
    • Asia Pacific
      • China
      • India
      • Japan
      • Australia
      • South Korea
      • ASEAN
      • Rest of Asia Pacific
    • Middle East
      • GCC Countries
      • Israel
      • Rest of Middle East
    • Africa
      • South Africa
      • North Africa
      • Central Africa
  • Company Profiles
    • Thermo Fisher Scientific Inc.
    • Merck KGaA
    • GE Healthcare
    • Lonza Group Ltd.
    • STEMCELL Technologies Inc.
    • BioLife Solutions, Inc.
    • Cryolife, Inc.
    • Organ Recovery Systems Inc.
    • Custom Biogenic Systems
    • Sartorius AG
    • Takara Bio Inc.
    • Chart Industries, Inc.
    • Biocision, LLC
    • Cardinal Health, Inc.
    • Helmer Scientific

Sources

Primary Research Interviews from the following stakeholders

Stakeholders

  • Biotechnology and Pharmaceutical Companies (e.g., Thermo Fisher Scientific, BioLife Solutions, Lonza Group, Merck KGaA)
  • Healthcare Providers and Laboratory Managers (working in IVF centers, stem cell banks, and oncology units)
  • Clinical Researchers and Investigators (specializing in regenerative medicine and cell-based therapies)
  • Academic Institutions and University Labs (focused on cryobiology and bio preservation)
  • Biobank Operators and Cryogenic Storage Solution Providers

Databases

  • U.S. FDA Drug and Device Database
  • WHO Global Health Observatory
  • National Institutes of Health (NIH)
  • Centers for Disease Control and Prevention (CDC)
  • GlobalData Healthcare
  • PubMed and ClinicalTrials.gov
  • World Bank Open Data

Magazines

  • BioPharma Dive
  • Pharma Times
  • Genetic Engineering & Biotechnology News (GEN)
  • Nature Biotechnology
  • Drug Discovery & Development

Journals

  • Cryobiology
  • Stem Cell Research & Therapy
  • Journal of Translational Medicine
  • Nature Reviews Drug Discovery
  • Regenerative Medicine Journal

Newspapers

  • The New York Times – Science & Health
  • The Guardian – Global Health Section
  • The Economic Times – Biotech & Pharma
  • Stat News
  • Financial Times – Healthcare & Life Sciences

Associations

  • International Society for Cell and Gene Therapy (ISCT)
  • International Society for Biological and Environmental Repositories (ISBER)
  • American Society for Reproductive Medicine (ASRM)
  • International Stem Cell Research Society (ISSCR)
  • European Society for Organ Transplantation (ESOT)

Public Domain Sources

  • World Bank
  • U.S. Census Bureau
  • United Nations Population Division
  • Eurostat
  • ResearchGate
  • WHO and NIH Publications

Proprietary Elements

  • CMI Data Analytics Tool
  • Proprietary CMI Repository of Market Data (last 8 years)
  • CMI Expert Interviews and Transcripts (Biotechnology & Life Sciences segment)

*Definition: The global cell cryopreservation market consists of companies that provide cell and tissue cryopreservation services and products for research and therapeutic applications. These supply cryopreservation media, storage containers, cooling equipment, and sample management software that allow biological samples such as stem cells, cells, and tissues to be preserved at very low temperatures (-80°C or below) for long periods of time. This preservation allows samples to be stored and maintained for future use in applications like regenerative medicine, drug discovery, and biobanking.

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About Author

Nikhilesh Ravindra Patel is a Senior Consultant with over 8 years of consulting experience. He excels in market estimations, market insights, and identifying trends and opportunities. His deep understanding of the market dynamics and ability to pinpoint growth areas make him an invaluable asset in guiding clients toward informed business decisions. He plays a instrumental role in providing market intelligence, business intelligence, and competitive intelligence services through the reports.

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Frequently Asked Questions

The Cell Cryopreservation Market is estimated to be valued at USD 12.44 Bn in 2025, and is expected to reach USD 53.64 Bn by 2032.

The CAGR of the Cell Cryopreservation Market is projected to be 23.2% from 2025 to 2032.

Growing demand for stem cell research and advancements in regenerative medicine are the major factor driving the growth of global cell cryopreservation market.

High cost of establishment and operations and stringent regulations for stem cell research are the major factors hampering the growth of global cell cryopreservation market.

In terms of product type, equipment segment is estimated to dominate the market in 2025.

Thermo Fisher Scientific Inc., Merck KGaA, GE Healthcare, Lonza Group Ltd., STEMCELL Technologies Inc., BioLife Solutions, Inc., Cryolife, Inc., Organ Recovery Systems Inc., Custom Biogenic Systems, Sartorius AG, Takara Bio Inc., Chart Industries, Inc., Biocision, LLC, Cardinal Health, Inc., Helmer Scientific are the major players.

North America is expected to lead the global cell cryopreservation market.

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