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  • Published On : Sep 2022
  • Code : CMI1293
  • Industry : Biotechnology
  • Pages : 402
  • Formats :

Cell expansion is the large scale artificial production of daughter cells from a single cell, to support medical research. Cell expansion requires the synthesis of new cell wall material and controlled loosening of the wall to allow it to stretch and increase in area. Cell expansion is used for life science related research and development, drug screening, drug development, etc.

  • Cell expansion market is expected to grow as there is increasing R&D activities for the use of cell therapy technique for the development of vaccines, antibiotics, and therapeutics by the key market players.
  • Cell expansion is used for various applications such as for the treatment of various diseases such as cancer, diabetes, etc.

Global Cell Expansion Market - Impact of the Coronavirus (COVID-19) Pandemic

The COVID-19 pandemic is expected to hamper the growth of the global cell expansion market, owing to restriction in the supply chain of drugs during the COVID-19 pandemic. For instance, according to data reported by United Nations Office on Drugs and Crime in July 2020, the effective measures taken to control the spread of COVID-19 pandemic has at the end badly affected to drug supply chain. Many countries across the world have reported an overall shortage of many types of drugs at the retail level. Supply chain affected the transport and production of all kind of drugs, which is expected to hamper the market of acute bacterial skin and skin structure infections.

The coronavirus (COVID-19) pandemic and consequent lockdown in various countries across the globe have impacted the financial status of businesses in healthcare sectors. Players operating in the global cell expansion market are facing major challenges on various fronts due to the COVID-19 pandemic. The major challenges include supply of raw materials required for manufacturing instruments and accessories used in cell expansion applications along with irregularities in transportation facility.

The global cell expansion market is estimated to be valued at US$ 16,035.5 Mn in 2022 and is expected to exhibit a CAGR of 11.8% over the forecast period (2022-2030)  

Figure 1: Global Cell Expansion Market Share, (%), Analysis, By Application, 2022

Cell Expansion  | Coherent Market Insights

Development of new technologies in cell expansion is expected to offer lucrative growth opportunities for players in the global cell expansion market, over the forecast period.

Development of new technologies in cell expansion is expected to offer lucrative growth opportunities for players in the global cell expansion market. For instance, in March 2022, WuXi Advanced Therapies, a wholly owned subsidiary of WuXi AppTec, announced the launch of Tetracycline-Enabled Self-Silencing Adenovirus (TESSA), which is a state-of-the-art novel process for scalable manufacture of transfection-free adeno-associated virus (AAV) at Good Manufacturing Practice (GMP) grade. TESSA, is developed by OXGENE in the U.K., a WuXi Advanced Therapies firm, which will speed up AAV manufacture and lower the cost of cell and gene therapies manufacturing, allowing worldwide customers to offer more accessible ground-breaking treatments to patients as rapidly as feasible.

Key players are involved in launching of a new medium for the expansion and maintenance of cells is expected to drive the growth of global cell expansion market, over the forecast period.

Key players are involved in launching of a new medium for the expansion and maintenance of cells is expected to drive the growth of global cell expansion market. For instance, in September 2021, Bio-Techne Corporation, which develops, manufactures, and sells life science reagents, instruments, and services for the research, diagnostic, and bioprocessing markets, announced the launch of a new medium for the expansion and maintenance of induced pluripotent stem cells (iPSCs), which can be used in both research and translational workflows. The ExCellerate iPSC Expansion Medium is the newest addition to Bio-Techne's regenerative medicine portfolio.

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Cell Expansion Market Report Coverage

Report Coverage Details
Base Year: 2021 Market Size in 2022: US$ 16,035.5 Mn
Historical Data for: 2017 to 2020 Forecast Period: 2022 to 2030
Forecast Period 2022 to 2030 CAGR: 11.8% 2030 Value Projection: US$ 39,256.2 Mn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Product: Consumables (Media, Others), Instruments (Automated Cell, Expansion Systems, Cell Counters, Centrifuges, Bioreactors, Others), Accessories
  • By Cell Type: Mammalian Cells (Human Cells (Stem Cells, Adult Stem Cells, Induced Pluripotent Stem Cells, Embryonic Stem Cells), Differentiated Cells, Animal Cells), Microbial Cells, Others (Plant-derived Cells)
  • By Application: Biopharmaceuticals, Tissue Culture & Engineering, Vaccine Production, Drug Development, Cancer Research, Stem Cell Research, Other Applications
  • By End User: Biotechnology Companies, Biopharmaceutical Companies, Others
Companies covered:

Becton, Dickinson and Company, Sartorius AG, Merck KGaA, Corning, Inc., Eppendorf SE, Lonza Group AG, PromoCell, Danaher, Thermo Fisher Scientific, HiMedia Laboratories, STEMCELL Technologies Inc., REPROCELL Inc., Bio-Techne, Valiant Co., Ltd., Miltenyi Biotec, Biologos, Cyagen US Inc.

Growth Drivers:
  • Development of new technologies in cell expansion
  • Launching of a new medium for the expansion and maintenance of cells by key market players
Restraints & Challenges:
  • Increasing acquisition by market players of cell and gene therapy manufacturing facilities
  • Restrictions created by ethical authorities for the use of human embryos

Global Cell Expansion Market – Restraints

Animal and human cells are also utilized to evaluate medicines for in vivo toxicity and pharmacokinetics in animals and humans. Furthermore, stem cell research uses human embryos for clinical purposes, which frequently results in the killing of human embryos.  Stringent restrictions have been created by ethical authorities such as The Human Tissue Authority (HTA), the Human Fertilization and Embryology Authority (HFEA), etc. in numerous nations across the world to supervise these operations. For instance, prohibitions under the 1990 Act on Human Embryo Research by the Human Fertilization and Embryology Authority includes, keeping or using an embryo after the appearance of the primitive streak, or after 14 days whichever is the earlier, placing an embryo in a non-human animal, placing non-human gametes or embryos in a woman, replacing a nucleus of a cell of an embryo with a nucleus taken from the cell of another person, another embryo, or a subsequent development of an embryo, altering the genetic structure of any cell while it forms part of an embryo.

Global Cell Expansion Market – Regional Analysis

On the basis of region, the global cell expansion market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa

Among regions, North America cell expansion market is expected to hold a dominant position during the forecast period, owing to the increasing acquisition by market players of cell and gene therapy manufacturing facilities in the region. For instance, in July 2021, AGC Biologics, a major global biopharmaceutical contract development and manufacturing organization (CDMO), signed a purchase agreement with Novartis Gene Therapies, a division of Novartis AG to acquire a state-of-the-art cell and gene therapy commercial manufacturing facility in Longmont, Colorado, U.S. The facility will provide AGC Biologics with significant extra capacity and space, pending full due diligence, to continue to develop its end-to-end Cell and Gene Therapy (C&GT) offering, assuring supply security for current and future C&GT clients.

Furthermore, Europe is expected to exhibit significant growth in the cell expansion market, owing to increasing facility expansion and investment in cell and gene therapy manufacturing by market players in this region. For instance, in March 2021, GSK, a science-led global healthcare company, announced the agreement with Cell and Gene Therapy Catapult, a non-profit organization dedicated to the improvement of cell and gene therapies through creativity and technology, to expand its clinical trial manufacturing capacity for cell and gene therapy at the Cell and Gene Therapy Catapult facility in Stevenage, U.K.

Figure 2: Global Cell Expansion Market (US$ Bn), by Region, 2022

Cell Expansion  | Coherent Market Insights

Global Cell Expansion Market – Competitive Landscape

Major players operating in the global cell expansion market include Becton, Dickinson and Company, Sartorius AG, Merck KGaA, Corning, Inc., Eppendorf SE, Lonza Group AG, PromoCell, Danaher, Thermo Fisher Scientific, HiMedia Laboratories, STEMCELL Technologies Inc., REPROCELL Inc., Bio-Techne, Valiant Co., Ltd., Miltenyi Biotec, Biologos, Cyagen US Inc.  

Cell expansion is the production of daughter cells from a single cell. Cell expansion requires the creation of new cell wall material and organized releasing of the wall to allow it to stretch and increase in area. Cell-wall-associated proteins are key components in cell expansion process. Expansions increase wall extensibility, presumably by breaking non covalent bonds between wall polysaccharides.

Due to growing demand for regenerative drugs offering faster outcomes and cellular based treatments plans with affected individual’s compatibility is predictable to boost the cell expansion market growth. Key market players are involved in developing cell based products and therapies. Development of new technologies in cell expansion is expected to offer lucrative growth opportunities for players in the global cell expansion market.

Market Dynamics

Increasing R&D activities in cell expansion is expected to aid in growth of the global cell expansion market over the forecast period. For instance, in November 2021, FUJIFILM Irvine Scientific, Inc., a world leader in providing cell culture solutions for life science and medical markets, announced the expansion of its Armstrong R&D Center of Excellence at its headquarters in California. This expansion marks an ongoing commitment to the advancement of discovery research, bio production, cell and gene therapy, assisted reproductive technologies and cytogenetics in its life sciences and medical media divisions.

Increasing prevalence of cancer and infectious diseases is expected to drive the cell expansion market growth over the forecast period. For instance, according to the World Health Organization (WHO): February 2022, cancer is the second leading cause of death globally, and is responsible for an estimated 10 million deaths in 2020, globally. Furthermore, globally, about 1 in 6 deaths occurred due to cancer. Cell expansion is used for various applications such as for the treatment of various diseases and are used in R&D for cell therapy technique to develop drugs, vaccines, antibiotics, etc.

Key features of the study:

  • This report provides an in-depth analysis of the global cell expansion market, provides market size (US$ Million), and compound annual growth rate (CAGR %) for the forecast period (2022-2030), considering 2021 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, regional outlook, and competitive strategies adopted by the leading players
  • It profiles leading players in the global cell expansion market based on the following parameters – company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies, and future plans
  • Key companies covered as a part of this study include Becton, Dickinson and Company, Sartorius AG, Merck KGaA, Corning, Inc., Eppendorf SE, Lonza Group AG, PromoCell, Danaher, Thermo Fisher Scientific, HiMedia Laboratories, STEMCELL Technologies Inc., REPROCELL Inc., Bio-Techne, Valiant Co., Ltd., Miltenyi Biotec, Biologos, Cyagen US Inc.
  • Insights from this report would allow marketers and management authorities of the companies to make informed decision regarding their future product launch, technology up-gradation, market expansion, and marketing tactics
  • The global cell expansion market report caters to various stakeholders in this industry including investors, suppliers, manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global cell expansion market

Detailed Segmentation:

  • Global Cell Expansion Market, By Product:
    • Consumables
      • Media
      • Others
    • Instruments
      • Automated Cell
      • Expansion Systems
      • Cell Counters
      • Centrifuges
      • Bioreactors
      • Others
    • Accessories
  • Global Cell Expansion Market, By Cell Type:
    • Mammalian Cells
      • Human Cells
        • Stem Cells
        • Adult Stem Cells
        • Induced Pluripotent Stem Cells
        • Embryonic Stem Cells
      • Differentiated Cells
      • Animal Cells
    • Microbial Cells
    • Others (Plant-derived Cells)
  • Global Cell Expansion Market, By Application:
    • Biopharmaceuticals
    • Tissue Culture & Engineering
    • Vaccine Production
    • Drug Development
    • Cancer Research
    • Stem Cell Research
    • Other Applications
  • Global Cell Expansion Market, By End User:
    • Biotechnology Companies
    • Biopharmaceutical Companies
    • Others
  • Global Cell Expansion Market, By Region:
    • North America
      • By Country:
        • U.S.
        • Canada
    • Latin America
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Country:
        • U.K.
        • Germany
        • Italy
        • Spain
        • France
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Country:
        • Australia
        • India
        • China
        • Japan
        • ASEAN
        • South Korea
        • Rest of Asia Pacific
    • Middle East
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Country/Region:
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Becton, Dickinson and Company *
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Recent Highlights
      • Strategies
    • Sartorius AG
    • Merck KGaA
    • Corning, Inc.
    • Eppendorf SE
    • Lonza Group AG
    • PromoCell
    • Danaher
    • Thermo Fisher Scientific
    • HiMedia Laboratories
    • STEMCELL Technologies Inc.
    • REPROCELL Inc.
    • Bio-Techne
    • Valiant Co., Ltd.
    • Miltenyi Biotec
    • Biologos
    • Cyagen US Inc.

“*” marked represents similar segmentation in other categories in the respective section.

Frequently Asked Questions

Global cell expansion market is expected to exhibit a CAGR of 11.8% during the forecast period (2022-2030).
The market is estimated to be valued at US$ 16,035.5 Mn in 2022.
Becton, Dickinson and Company, Sartorius AG, Merck KGaA, Corning, Inc., Eppendorf SE, Lonza Group AG, PromoCell, Danaher, Thermo Fisher Scientific, HiMedia Laboratories, STEMCELL Technologies Inc., REPROCELL Inc., Bio-Techne, Valiant Co., Ltd., Miltenyi Biotec, Biologos, Cyagen US Inc. are some of the prominent players operating in the market.
The is expected to be valued at US$ 39,256.2 Mn in 2030.
North America is the prominent region in the market.
Consumables is the prominent segment among the product segment in the market.

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