CLUSTER HEADACHE MARKET ANALYSIS

A cluster headache (CH) is a rare type of headache. The attack lasts for 15 minutes to three hours, occurs daily or almost daily for weeks or months. The causes of cluster headache appears to be related to the body's sudden release of histamine (a chemical in the body that is released during an allergic reaction) or serotonin (a chemical produced by nerve cells) in the area of a nerve situated in the face called the trigeminal nerve. A problem may be involved in a small area at the base of the brain called the hypothalamus. Cluster headache can be triggered by alcohol and smoking cigarette, high altitudes, bright lights, exertion, heat, foods rich in nitrite, certain drugs, and cocaine.

Some types of acute treatment (oxygen, tripants, octreotide, and others), preventive treatment (calcium channel blockers, corticosteroids, lithium carbonate, and others), and surgery in severe cases can provide some pain relief.

The global cluster headache market is estimated to be valued at US$ 355.2 Million in 2021 and is expected to increase to US$ 550.1 Million by 2028, witnessing a CAGR of 6.4% over the forecast period (2021-2028).

Figure 1. Global Cluster Headache Market Value (US$ Mn) & Y-o-Y Growth (%)

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Increasing prevalence of cluster headache patients with a positive family history is expected to drive the growth of the global cluster headache market.

Increasing prevalence of cluster headache patients with a positive family history is expected to drive the growth of the global cluster headache market. For instance, according to a research article published by BMC (Bio med central) in April 2020, a systematic review and meta-analysis was carried out in accordance with the guidelines for preferred reporting items for systematic reviews and meta-analysis protocols (PRISMA- P). It was found that an estimated prevalence of CH patients with a family history was around 6.27% with an overall I² of 73%.

Figure 2. Global Cluster Headache Market Share (%), By Region, 2021

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Global Cluster Headache Market – Impact of Coronavirus (COVID-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe. The coronavirus (COVID-19) pandemic and lockdown in various countries across the globe has impacted the financial status of businesses in all sectors. Private healthcare sector is one of the sector, which is majorly impacted by the COVID-19 pandemic.

The coronavirus pandemic has negatively impacted the development, production, and supply of pharmaceutical products and affected growth of the medication used in treatment of CH disease manufactured by various companies across the regions such as North America, Europe, and Asia Pacific. Moreover, the production and supply of pharmaceutical products is also affected due to lockdown imposed globally during the COVID-19 pandemic. Moreover, screen time of people during COVID-19 has continued to increase due to public health measures imposed by the government to contain the pandemic, which will drive the global market for cluster headache.

Global Cluster Headache Market: Restraint

Insufficient awareness among healthcare providers and unfavorable healthcare policies negatively impacting overall healthcare spending is hampering the global cluster headache market.

Key Players

Major players operating in the global cluster headache market include Zosano Pharma, Eli Lilly and Company, Lundbeck Seattle BioPharmaceutical, Winston Laboratories, GlaxoSmithKline plc., ElectroCore Medical LLC, Autonomic Technologies, Inc., AstraZeneca plc., Allergan plc., Bayer AG, F. Hoffmann-La Roche Ltd, Novartis AG, Sun Pharmaceutical Industries Ltd, Teva Pharmaceutical Industries Ltd., Takeda Pharmaceutical Company Limited, Sanofi, and AbbVie Inc.