Custom Recombinant Protein Production Services Market - Global Forecast to 2026, by Expression System  (Mammalian, Bacteria, Insect, Yeast, and Others), by End User (Research Institutes, Biotechnology and Pharmaceutical Companies, Contract Research Organizations, and Others), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa)- Size, Share, Outlook, and Opportunity Analysis, 2018 – 2026

  • Published On : Jun 2019 |
  • Pages : 190 Pages |
  • Format : CMI Insight PPT Format CMI Insight PDF Format

Global Custom Recombinant Protein Production Services Market – Market Insights

Custom recombinant protein production plays a major role in advanced healthcare and is the most efficient technique used in life sciences. Recombinant proteins are used in a wide range of applications in research, biotechnology, and medicine.

The global custom recombinant protein production services market size was valued at US$ 2,600.21 million in 2017, and is expected to exhibit a CAGR of 11.2% over the forecast period (2018 – 2026).

Figure 1. Global Custom Recombinant Protein Production Services Market Value (US$ Mn), by Region, 2017

                                                                         Source: Coherent Market Insights (2019)

Increasing funding in the field of life sciences is expected to propel growth of the custom recombinant protein production services market

Recombinant protein is a manipulated form of protein, which is encoded by genes. It is used in production of large quantities of protein, which is further used for manufacturing of therapeutic commercial products. Increasing government initiatives and funding in the field of life sciences is expected to boost growth of the market. For instance, Life Sciences Greenhouse of Central Pennsylvania offers early stage funding of up to US$ 1-2 million in the form of convertible debt or equity financing to viable life sciences companies, which have significant potential for commercial growth.

Moreover, advancements in bioreactor systems have facilitated production of recombinant protein within shorter time span, which in turn is expected to propel growth of the custom recombinant protein production services market over the forecast period. For instance, according to National Centre for Biotechnology Information (NCBI), in 2014, around 65.6% of clinical scale manufacturers and 42% of commercial manufacturers adopted single-use bioreactors for improvement in their bioprocessing.

However, high cost of recombinant protein for particular requirement is expected to hinder the market growth. The price of protein synthesis services ranges from US$ 3 to US$ 160 per amino acid depending upon the purity of the desired product. Moreover, the price of recombinant protein production services varies from US$ 500 to US$ 5000 per milligram depending upon the protein production expression systems, species of the proteins, and the family to which these recombinant proteins belong.

Figure 2. Global Custom Recombinant Protein Production Services Market Share (%), by Expression System,2018 and 2026

Source: Coherent Market Insights (2019)

Increasing research and development and product launches in North America is expected to bolster the market growth

North America is expected to hold dominant position in the global custom recombinant protein production services market, owing to increasing focus of regional players in research and development and product launches. For instance, in 2014, Western Blot Service CRO, a division of Altogen Lab, launched automated WES protein analysis and protein expression services, providing a complete platform to conduct protein expression studies.

Moreover, the companies in the region are focused on adopting strategic acquisitions to expand their geographic presence. For instance, in 2017, Eurofins Scientific acquired DiscoverX to improve research productivity and accelerate the discovery and development of new drugs. The acquisition is also expected to create a robust portfolio of kinase products and services in the market.

Furthermore, in 2014, Novoprotein participated in AAPS National Biotechnology Conference, which was dedicated to recent developments of protein recombinants, worldwide. The conference was focused on the overall development of the protein recombinant industry.

Key Players

Major players operating in the custom recombinant protein production services market include, GenScript Biotech Corporation, Applied Biological Materials Inc., Eurofins Pharma Discovery Services, Abgent, OriGene Technologies, Inc., Crown Bioscience, Inc., BPS Bioscience, Inc., ProteoGenix, Kempbio, Inc., Novoprotein, Premas Biotech, Trenzyme GmbH, Atum, Novus Biologicals, LLC, Icosagen AS, LakePharma, Inc., Proteos, Inc., Aldevron, and Sino Biological Inc.

Recombinant proteins are used in development of novel therapies for severe chronic diseases such as cancer and other rare diseases. Recombinant protein production requires a special technique known as recombinant DNA (rDNA) technology. Recombinant proteins have immense potential in cancer therapy research and development. For instance, growth factors, immune checkpoint, and cell damage & oxidative stress proteins (preclinical stage) are utilized from recombinant proteins category for cancer therapy research.

Market Dynamics

Increasing demand for recombinant proteins for basic research has supported growth of the custom recombinant protein production services market. Recombinant therapeutic proteins are one of the fast-growing areas in molecular medicine. Various biopharmaceutical companies are focusing on development of biologics and subsequently biosimilars. Moreover, increasing expenditure in research has supported the market growth. The R&D spending of the U.S. is around 2.7% of its Gross Domestic Products (GDP) with highest R&D investments observed in the biotechnology segment in 2014, according to American Pharmaceutical Review.

Moreover, major players in the market are focused on launching new facilities to cater to increasing demand for research and development, which is expected to drive the market growth. For instance, in 2016, ATUM established a new state-of-the-art bio-production facility in Newark, California, for rapid expansion and to provide better services to the customers.

However, high cost of protein expression systems and complex manufacturing procedures are the major factors restraining the market growth over the forecast period. For instance, the price of recombinant protein production services varies from US$ 500 to US$ 5000 per milligram depending upon the protein production expression systems, species of the proteins, and the family to which these recombinant proteins belong.

Key features of the study:

  • This report provides in-depth analysis of the custom recombinant protein production services market and provides market size (US$ million) and Compound Annual Growth Rate (CAGR %) for the forecast period (2018 – 2026), considering 2017 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends,  regional outlook, and competitive strategy adopted by key players
  • It profiles key players in the global custom recombinant protein production services market based on the following parameters – company overview, financial performance, product portfolio, market presence, distribution strategies, key developments, strategies, and future plans
  • Key companies covered as a part of this study include, GenScript Biotech Corporation, Applied Biological Materials Inc., Eurofins Pharma Discovery Services, Abgent, OriGene Technologies, Inc., Crown Bioscience, Inc., BPS Bioscience, Inc., ProteoGenix, Kempbio, Inc., Novoprotein, Premas Biotech, Trenzyme GmbH, Atum, Novus Biologicals, LLC, Icosagen AS, LakePharma, Inc., Proteos, Inc., Aldevron, and Sino Biological Inc.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, technology up-gradation, market expansion, and marketing tactics.
  • The global custom recombinant protein production services market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the custom recombinant protein production services market

Detailed Segmentation:

  • Global Custom Recombinant Protein Production Services Market, By Expression System:
    • Mammalian
    • Bacteria
    • Insect
    • Yeast
    • Others
  • Global Custom Recombinant Protein Production Services, By End User:
    • Research Institutes
    • Biotechnology and Pharmaceutical Companies
    • Contract Research Organizations
    • Others
  • Global Custom Recombinant Protein Production Services Market, By Geography:
    • North America
      • By Expression System:
        • Mammalian
        • Bacteria
        • Insect
        • Yeast
        • Others
      • By End User:
        • Research Institutes
        • Biotechnology and Pharmaceutical Companies
        • Contract Research Organizations
        • Others
      • By Country:
        • U.S.
        • Canada
    • Latin America
      • By Expression System:
        • Mammalian
        • Bacteria
        • Insect
        • Yeast
        • Others
      • By End User:
        • Research Institutes
        • Biotechnology and Pharmaceutical Companies
        • Contract Research Organizations
        • Others
      • By Country:
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Expression System:
        • Mammalian
        • Bacteria
        • Insect
        • Yeast
        • Others
      • By End User:
        • Research Institutes
        • Biotechnology and Pharmaceutical Companies
        • Contract Research Organizations
        • Others
      • By Country:
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Expression System:
        • Mammalian
        • Bacteria
        • Insect
        • Yeast
        • Others
      • By End User:
        • Research Institutes
        • Biotechnology and Pharmaceutical Companies
        • Contract Research Organizations
        • Others
      • By Country:
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Expression System:
        • Mammalian
        • Bacteria
        • Insect
        • Yeast
        • Others
      • By End User:
        • Research Institutes
        • Biotechnology and Pharmaceutical Companies
        • Contract Research Organizations
        • Others
      • By Country:
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Expression System:
        • Mammalian
        • Bacteria
        • Insect
        • Yeast
        • Others
      • By End User:
        • Research Institutes
        • Biotechnology and Pharmaceutical Companies
        • Contract Research Organizations
        • Others
      • By Country:
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • GenScript Biotech Corporation*
      • Company Overview
      • Product Portfolio
      • Financial Performance
      • Key Highlights
      • Market Strategies
    • Applied Biological Materials Inc.
    • Eurofins Pharma Discovery Services
    • Abgent
    • OriGene Technologies, Inc.
    • Crown Bioscience, Inc.
    • BPS Bioscience, Inc.
    • ProteoGenix
    • Kempbio, Inc.
    • Novoprotein
    • Premas Biotech
    • Trenzyme GmbH
    • Atum
    • Novus Biologicals, LLC
    • Icosagen AS
    • LakePharma, Inc.
    • Proteos, Inc.
    • Aldevron
    • Sino Biological Inc.

“*” marked represents similar segmentation in other categories in the respective section.

Table of Contents

  1. Research Objectives and Assumptions
    • Research Objectives
    • Assumptions
    • Abbreviations
  2. Market Purview
    • Report Description
      • Market Definition and Scope
    • Executive Summary
      • Market Snippet, By Expression System
      • Market Snippet, By End User
      • Market Snippet, By Region
    • Coherent Opportunity Map (COM)
  3. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
    • Impact Analysis
    • Pipeline Analysis
    • Reimbursement Scenario
    • Pest Analysis
    • Regulatory Scenario
    • Collaborations and Agreements
    • Market Trends
  4. Global Custom Recombinant Protein Production Services Market, By Expression System, 2018 – 2026, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Mammalian
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Mn)
    • Bacteria
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Mn)
    • Insect
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Mn)
    • Yeast
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Mn)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Mn)
  5. Global Custom Recombinant Protein Production Services Market, By End User, 2018 – 2026, (US$ Mn)
    • Introduction
      • Market Share Analysis, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, 2017 – 2026
      • Segment Trends
    • Research Institutes
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Mn)
    • Biotechnology and Pharmaceutical Companies
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Mn)
    • Contract Research Organizations
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Mn)
    • Others
      • Introduction
      • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Mn)
  6. Global Custom Recombinant Protein Production Services Market, By Region, 2018 – 2026, (US$ Mn)
    • Introduction
      • Market Share Analysis, By Region, 2018 and 2026 (%)
      • Y-o-Y Growth Analysis, For Regions, 2017–2026
    • North America
      • Market Size and Forecast, By Expression System, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Mn)
        • U.S.
        • Canada
    • Latin America
      • Market Size and Forecast, By Expression System, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Mn)
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • Market Size and Forecast, By Expression System, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Mn)
        • Germany
        • U.K.
        • France        
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast, By Expression System, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Mn)
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of APAC
    • Middle East
      • Market Size and Forecast, By Expression System, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Mn)
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • Market Size and Forecast, By Expression System, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By End User, 2016 – 2026, (US$ Mn)
      • Market Size and Forecast, By Country, 2016 – 2026, (US$ Mn)
        • South Africa
        • Central Africa
        • North Africa
  7. Competitive Landscape
    • Heat Map Analysis
    • Company Profiles
      •  GenScript Biotech Corporation
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Applied Biological Materials Inc.
        •  Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Eurofins Pharma Discovery Services
        •  Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Abgent
        •  Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      •  OriGene Technologies, Inc.
        •  Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Crown Bioscience, Inc.
        •  Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • BPS Bioscience, Inc.
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • ProteoGenix
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Kempbio, Inc.
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Novoprotein
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Premas Biotech
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Trenzyme GmbH
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Atum
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Novus Biologicals, LLC
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Icosagen AS
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • LakePharma, Inc.
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Proteos, Inc.
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Aldevron
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
      • Sino Biological Inc.
        • Company Overview
        • Product Type Portfolio
        • Financial Overview
        • Key Highlights
        • Market Strategies
    • Analyst Views
  8. Section
    • References
    • Research Methodology
    • About us and Sales Contact

*Browse 37 market data tables and 29 figures on "Custom Recombinant Protein Production Services Market - Global forecast to 2026”.

Research Methodology

Coherent Market Insights followsa comprehensive research methodology focused on providing the most precise market analysis. The company leverages a data triangulation model which helps company to gauge the market dynamics and provide accurate estimates. Key components of the research methodologies followed for all our market reports include:

  • Primary Research (Trade Surveys and Experts Interviews)
  • Desk Research
  • Proprietor Data Analytics Model

In addition to this, Coherent Market Insights has access to a wide range of the regional and global reputed paid data bases, which helps the company to figure out the regional and global market trends and dynamics. The company analyses the industry from the 360 Degree Perspective i.e. from the Supply Side and Demand Side which enables us to provide granular details of the entire ecosystem for each study. Finally, a Top-Down approach and Bottom-Up approach is followed to arrive at ultimate research findings.


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Coherent Market Insights desk research is based on a principle set of research techniques:

  • National level desk research: It Includes research analysis of regional players, regional regulatory bodies, regional trade associations, and regional organization.
  • Multinational level desk research: The research team keeps a track of multinational players, global regulatory bodies, global trade associations, and global organization.

Coherent Market Insights has a large amount of in-house repository of industry database. This is leveraged as a burner for initiating a new research study. Key secondary sources include:

  • Governmental bodies, National and international social welfare institutions, and organizations creating economic policies among others.
  • Trade association, National and international media and trade press.
  • Company Annual reports, SEC filings, Corporate Presentations, press release, news, and specification sheet of manufacturers, system integrators, brick and mortar - distributors and retailers, and third party online commerce players.
  • Scientific journals, and other technical magazines and whitepapers.

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Preliminary Data Mining

The raw data is obtained through the secondary findings, in house repositories, and trade surveys. It is then filtered to ensure that the relevant information including industry dynamics, trends, and outlook is retained for further research process.

Data Standardization:

Holistic approach is used to ensure that the granular and uncommon parameters are taken into consideration to ensure accurate results. The information from the paid databases are further combined to the raw data in order to standardize it.

Coherent Statistical model

We arrive at our final research findings through simulation models. Coherent Data Analytics Model is a statistical tool that helps company to forecast market estimates. Few of the parameters considered as a part of the statistical model include:

  • Micro-economic indicators
  • Macro-economic indicators
  • Environmental indicators
  • Socio-political indicators
  • Technology indicators

Data Processing

Once the findings are derived from the statistical model, large volume of data is process to confirm accurate research results. Data analytics and processing tools are adopted to process large chunk of collected informative data. In case, a client customizes the study during the process, the research finding till then are benchmarked, and the process for new research requirement is initiated again.

Data Validation

This is the most crucial stage of the research process. Primary Interviews are conducted to validate the data and analysis. This helps in achieving the following purposes:

  • It provides first-hand information on the market dynamics, outlook, and growth parameters.
  • Industry experts validates the estimates which helps the company to cement the on-going research study.
  • Primary research includes online surveys, face-to face interviews, and telephonic interviews.

The primary research is conducted with the ecosystem players including, but not limited to:

  • Raw Material Suppliers
  • Manufacturers
  • System Integrators
  • Distributors
  • End-users

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