all report title image
  • Published On : Jul 2022
  • Code : CMI1664
  • Industry : Pharmaceutical
  • Pages : 173
  • Formats :

Dementia is one of the most prevalent neurodegenerative diseases in which patients suffer from various behavioral changes, with primary symptoms such as decline in memory or other thinking skills, which can get worse as the condition progresses. It majorly affects people aged 65 years and above. There is no curative therapy available for dementia disease. However, drugs for dementia therapy are in pipeline, which are expected to be launched over forecast period, in turn propelling growth of the dementia drugs market.

Global dementia drugs market is estimated to be valued at US$ 20,677.0 million in 2022 and is expected to exhibit a CAGR of 8.5% during the forecast period (2022-2030).

Figure 1. Global Dementia Drugs Market Share (%), By Drug Class, 2022

Dementia Drugs  | Coherent Market Insights

Increasing clinical trials for drug development for treatment of dementia are expected to drive growth of the global dementia drugs market.

Increasing clinical trials for drug development for treatment of dementia are expected to drive growth of the global dementia drugs market. For instance, On May 6, 2022, A Monash University, Australia published a study that has shown promising results as brand-new therapy for dementia patients under the age of 60 that stabilizes rising behavioral problems and reverses the disease's effects on brain shrinkage. It is the second clinical trial to show that the drug, sodium selenate, may be slowing cognitive decline and neurodegenerative damage that of Alzheimer’s disease and dementia. The Monash Phase 1 trial, the only one in Australia targeting this type of behavioral variant of frontotemporal dementia (bvFTD), and one of a handful worldwide, showed that sodium selenate is safe and well-tolerated in patients with bvFTD over a period of 12 months.

CMI table icon

Dementia Drugs Market Report Coverage

Report Coverage Details
Base Year: 2021 Market Size in 2021: US$ 20,677.0 Mn
Historical Data for: 2017 to 2020 Forecast Period: 2022 to 2030
Forecast Period 2022 to 2030 CAGR: 8.5% 2030 Value Projection: US$ 39,663.6 Mn
Geographies covered :
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Drug Class: MAO Inhibitors, Cholinesterase Inhibitors, Glutamate Inhibitor
  • By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Others
Companies covered:

Eisai, Inc., Janssen Pharmaceuticals, Inc., Biogen Pharmaceuticals, Forest Laboratories, Inc., Eli Lilly and Company, Novartis AG, Sanofi S.A., AstraZeneca GmbH, F. Hoffmann-La Roche, Merck & Co., Inc., Valeant Pharmaceutical International, Pfizer Inc., and Teva Pharmaceuticals Industries Ltd.

Growth Drivers:
  • Increasing clinical trials for drug development for treatment of dementia
  • Increasing incidence of Alzheimer’s disease worldwide
Restraints & Challenges:
  • Failure of investigational candidates in late stage

Figure 2.Global Dementia Drugs Market Share (%), by Region, 2022

Dementia Drugs  | Coherent Market Insights

Increasing incidence of Alzheimer’s disease worldwide is expected to drive growth of the dementia drugs market over the forecast period.

Increasing incidence of Alzheimer’s disease worldwide is expected to drive growth of the dementia drugs market over the forecast period. For instance, According to data published by The Centers for Disease Control and Prevention (CDC), Alzheimer’s disease is the most common cause of dementia among older adults. 6.2 million U.S. citizens  were estimated to be living with Alzheimer’s disease in 2021. In U.S. dementia is the fifth leading cause of death for adults aged 65 years and older, and the sixth leading cause of death for all adults.

Global Dementia Drugs Market- Impact of Coronavirus (Covid-19) Pandemic

Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 100 countries across the globe and the World Health Organization declared it a public health emergency on January 30, 2020.

The COVID-19 can affect the economy in three main ways: by directly affecting the production and demand of drugs, by creating disruptions in distribution channels, and through its financial impact on firms and financial markets. Due to nationwide lockdowns, several countries such as China, India, Saudi Arabia, the U.A.E., Egypt, and others are facing problems with regard to the transportation of drugs from one place to another.

However, the COVID-19 pandemic had a negative impact on the global dementia drugs market, owing to the effects of the COVID-19 pandemic on patients with dementia. For instance, on January 6, 2021, an article published in The Nature journal stated that patients with dementia and Alzheimer's disease were particularly at danger because of the COVID-19 pandemic. According to same article in 2020, individuals were at danger of developing serious COVID-19 and neuropsychiatric disorders as a result of lockout procedures and social isolation.

Global Dementia Drugs Market: Key Developments

On June 27, 2022, Otsuka Pharmaceutical Co., Ltd., a pharmaceutical company and H. Lundbeck A/S, a manufacturing company of pharmaceuticals, announced positive results of the phase III clinical trial of brexpiprazole in the treatment of agitation in patients with Alzheimer's disease and dementia. The analysis concluded that there is a statistically significant difference in the mean change from baseline between brexpiprazole and placebo.

Global Dementia Drugs Market: Restraint

The major factors that hinder growth of the global dementia drugs market include failure of investigational candidates in late stage. For instance, On June 12, 2018, AstraZeneca, a biopharmaceutical company and Eli Lilly and Company, a pharmaceutical company announced the discontinuation of the global Phase III clinical trials of lanabecestat, an oral beta secretase cleaving enzyme (BACE) inhibitor, for the treatment of Alzheimer’s disease. The decision was based on recommendations by an independent data monitoring committee (IDMC), which concluded that both the AMARANTH trial, in early Alzheimer’s disease, and the DAYBREAK-ALZ trial, in mild Alzheimer’s disease dementia, were not likely to meet primary endpoints upon completion.

Key Players

Major players operating in the global dementia drugs market include Eisai, Inc., Janssen Pharmaceuticals, Inc., Biogen Pharmaceuticals, Forest Laboratories, Inc., Eli Lilly and Company, Novartis AG, Sanofi S.A., AstraZeneca GmbH, F. Hoffmann-La Roche, Merck & Co., Inc., Valeant Pharmaceutical International, Pfizer Inc., and Teva Pharmaceuticals Industries Ltd.

Dementia is a form of disease that affects the functioning of the brain resulting in decline in memory or other thinking skills. Alzheimer’s disease is the most common and largest form of dementia (in over 60% cases), which is observed among people aged 65 years and above. Dementia results from a variety of diseases and injuries that primarily or secondarily affect the brain, such as Alzheimer's disease or stroke. It affects memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgment. The impairment in cognitive function is commonly accompanied, and occasionally preceded, by changes in mood, emotional control, behavior, or motivation. Accumulation of a protein called beta amyloid in the spaces between nerve cells due to genetic mutation is a major cause of dementia. Although dementia is not treatable, symptomatic treatment is followed in all cases. Research is being carried out to develop therapies centered on the role of beta-amyloid in dementia.

Market Dynamics

Increasing product approval by regulatory authorities is the major driving factor for growth of the dementia drugs market. For instance, on June 24, 2021, Eli Lilly and Company, a pharmaceutical company announced the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy designation for donanemab, Eli Lilly and Company's investigational antibody therapy for Alzheimer's disease (AD). The Breakthrough Therapy designation aims to expedite development and review of drugs that are intended to treat a serious condition when preliminary clinical evidence indicates that the drug may demonstrate substantial improvement on a clinically significant endpoint(s) over already available therapies that have received full FDA approval. Dementia due to Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of all cases.

Key features of the study:

  • This report provides an in-depth analysis of the global dementia drugs  market, and provides market size (US$ Million) and compound annual growth rate (CAGR%) for the forecast period (2022–2030), considering 2021 as the base year
  • It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
  • It profiles key players in the global dementia drugs  market  based on the following parameters – company highlights, products portfolio, key highlights, financial performance, and strategies
  • Key companies covered as a part of this study include Eisai, Inc., Janssen Pharmaceuticals, Inc., Biogen Pharmaceuticals, Forest Laboratories, Inc., Eli Lilly and Company, Novartis AG, Sanofi S.A., AstraZeneca GmbH, F. Hoffmann-La Roche, Merck & Co., Inc., Valeant Pharmaceutical International, Pfizer Inc., and Teva Pharmaceuticals Industries Ltd.
  • Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
  • The global dementia drugs  market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
  • Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global dementia drugs  market

Detailed Segmentation:

  • Global Dementia Drugs Market, By Drug Class:
    • MAO Inhibitors
    • Cholinesterase Inhibitors
    • Glutamate Inhibitor
  • Global Dementia Drugs Market, By Distribution Channel:
    • Hospital Pharmacies
    • Retail Pharmacies
    • Others
  • Global Dementia Drugs Market, By Region:
    • North America
      • By Country
        • U.S.
        • Canada
    • Latin America
      • By Country
        • Brazil
        • Mexico
        • Argentina
        • Rest of Latin America
    • Europe
      • By Country
        • Germany
        • U.K.
        • France
        • Italy
        • Spain
        • Russia
        • Rest of Europe
    • Asia Pacific
      • By Country
        • China
        • India
        • Japan
        • Australia
        • South Korea
        • ASEAN
        • Rest of Asia Pacific
    • Middle East
      • By Country
        • GCC
        • Israel
        • Rest of Middle East
    • Africa
      • By Region/Country
        • South Africa
        • Central Africa
        • North Africa
  • Company Profiles
    • Eisai, Inc. *
      • Company Highlights
      • Products Portfolio
      • Key Highlights
      • Financial Performance
      • Strategies
    • Janssen Pharmaceuticals, Inc.
    • Biogen Pharmaceuticals
    • Forest Laboratories, Inc.
    • Eli Lilly and Company
    • Novartis AG
    • Sanofi S.A.
    • AstraZeneca GmbH
    • Hoffmann-La Roche
    • Merck & Co., Inc.
    • Valeant Pharmaceutical International
    • Pfizer Inc.
    • Teva Pharmaceuticals Industries Ltd.

 “*” marked represents similar segmentation in other categories in the respective section.

Frequently Asked Questions

The global dementia drugs market size is estimated to be valued at US$ 20,677.0 million in 2022 and is expected to exhibit a CAGR of 8.5% between 2022 and 2030.
Increasing clinical trials for drug development for treatment of dementia and increasing incidence of Alzheimer’s disease worldwide are major factors driving the market growth.
MAO Inhibitors is the leading drug class in the market.
The major factors hampering growth of the market include failure of investigational candidates in late stage.
Major players operating in the market include Eisai, Inc., Janssen Pharmaceuticals, Inc., Biogen Pharmaceuticals, Forest Laboratories, Inc., Eli Lilly and Company, Novartis AG, Sanofi S.A., AstraZeneca GmbH, F. Hoffmann-La Roche, Merck & Co., Inc., Valeant Pharmaceutical International, Pfizer Inc., and Teva Pharmaceuticals Industries Ltd.

Related Reports

EXISTING CLIENTELE

Joining thousands of companies around the world committed to making the Excellent Business Solutions.

View All Our Clients
trusted clients logo