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Endoprosthesis Market Analysis & Forecast: 2025-2032

Endoprosthesis Market, By Product Type (Knee Reconstruction, Hip Reconstruction, Extremities Reconstruction, Dental Reconstruction, Cardiac Reconstruction and Others (Spinal implant,Craniofacial reconstruction plates and bone grafts)), By Material (Metallic, Polymeric, Ceramic, Biological and Others (Bioresorbable materials, Composite materials)), By End-User (Hospitals, Orthopedic Clinics, Ambulatory Surgery Centers and Others (Specialty Clinics, Rehab Centers)), , By Geography (North America, Latin America, Europe, Middle East & Africa, and Asia Pacific)

  • Published In : Apr 2025
  • Code : CMI6199
  • Pages :165
  • Formats :
      Excel and PDF
  • Industry : Clinical Diagnostic

Endoprosthesis Market Size and Forecast – 2025-2032

The Endoprosthesis Market value is projected to reach USD 43.72 Bn by 2032 from 2025’s value of USD 26.35 Bn while maintaining a predicted Compound Annual Growth Rate (CAGR) of 7.5% between 2025 and 2032.

Key Takeaways

  • Based on Product, the knee reconstruction segment is anticipated to acquire the largest share in the overall market owing to the increasing worldwide coronary artery disease occurrences.
  • Based on Material, the market is bifurcated into Metallic, Polymeric, Ceramic, Biological, and Others (Bioresorbable materials, Composite materials). The demand for endoprostheses is increasing due to advancements in material technology, offering enhanced durability, biocompatibility, and functionality, which improve patient outcomes and recovery times.
  • By End User, the market is classified into Hospitals, Orthopedic Clinics, Ambulatory Surgery Centers, and Others (Specialty Clinics, Rehab Centers). The demand for these segments is primarily driven by the increasing prevalence of orthopedic diseases and the rising demand for minimally invasive procedures across various healthcare settings.
  • Based on Region, North America is expected to be the largest market for endoprosthesis market during the forecast period, accounting for over 40.2% of the market share in 2025 due to its high prevalence of cardiovascular diseases and aging population.

 Market Overview

 The worldwide Endoprosthesis Market is experiencing steady growth as a result of a growing need for orthopedic implants, particularly from the aging population prone to degenerative joint and cardiovascular diseases. The market is also being driven by growing trauma cases and road accidents in emerging economies, increased access to healthcare, and increased acceptance of new surgical techniques. Emerging technologies like intelligent implants with IoT and AI integrations are enabling real-time monitoring, which is revolutionizing postoperative care. Concurrently, there is increasing demand for minimally invasive procedures, as a result of shorter recovery times and less risk of complications. Together, these make endoprosthesis an essential part of modern medical procedures.

Current Events and Its Impact on Endoprosthesis Market

Current Events

Description and its impact

Aging Population and Increasing Prevalence of Orthopedic Disorders

  • Description: Growing demand for joint replacement surgeries
  • Impact: Increased demand for endoprostheses, driving market growth.

Technological Advancements in Endoprostheses

  • Description: Development of 3D-printed and customized implants
  • Impact: Enhanced patient outcomes and satisfaction, leading to higher adoption rates
  • Description: Integration of smart sensors and AI in endoprostheses
  • Impact: Improved monitoring and early detection of implant failures, reducing revision surgeries

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Segmental Analysis

Endoprosthesis Market By Product Type

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Endoprosthesis Market Insights, By Product Type- Rising Prevalence Of Orthopedic Diseases is Driving the Demand for Knee Reconstruction

 Knee reconstruction dominates the market and is expected to continue its leadership up to 2032. This is because the incidence of orthopedic diseases like osteoarthritis and osteopenia is rising among the elderly, and the prevalence of sports injuries is also on the rise. The world geriatric population is projected to increase to 2.11 billion by 2050, as per the United Nations, largely driving the need for knee implants.

Hip reconstruction implants are also showing consistent growth with the help of improving surgery techniques, increased success rates, and improved patient results. Shoulder and spinal implants are also on the rise as patients and practitioners want long-term, non-surgical, non-invasive orthopedic interventions for pain and mobility problems.

While so, cardiovascular implants such as heart valves, coronary stents, and pacemakers are fundamental to the treatment of coronary artery disease and structural heart disorders. As reported by the World Health Organization (WHO), cardiovascular disease ranks as the greatest cause of death worldwide with over 18 million deaths in one year alone. Consequently, cardiovascular endoprosthesis continues to increase significantly in demand in the North American and European continents where cardiovascular disease cases are rather common, thereby contributing to the endoprosthesis market growth.

Endoprosthesis Market Insights, By Material Type – Technological Advancements Are Enhancing Biocompatibility and Surgical Outcomes

Metallic materials, more specifically titanium and its alloys, acquires the prominent share in market of endoprosthesis owing to their superior mechanical properties and biocompatibility. Ti-6Al-4V is the most popular titanium alloy utilized in orthopedic implants, for hip and knee arthroplasty, owing to its high strength-to-weight ratio, corrosion resistance, and osseointegration with bone tissue potential. Moreover, polymeric materials such as ultra-high-molecular-weight polyethylene have been widely applied in joint prostheses as bearing surfaces based on their wear and low friction characteristics. Biological substances, like collagen composite and hydroxyapatite coatings, are used to facilitate the bonding of implants with bone tissues. These substances enhance the growth of bone and the stability of the implant and bioresorbing materials like polylactic acid (PLA) and polyglycolic acid (PGA) are increasingly being applied to temporary implantation and fixation devices. They have the potential for degradation of the body which eliminates the need for secondary surgical procedures for device removal, minimizing patient risk as well as health care expense.

Endoprosthesis Market Insights, By End-User Type

Hospitals acquires the most prominent share in the endoprosthesis market owing to their superior infrastructure, presence of multi-specialty services, and access to trained orthopedic surgeons. They perform most of the complicated procedures like total hip and knee arthroplasties, spinal reconstructions, and cardiovascular endoprostheses with the help of complete post-operative and intensive care facilities. Based on the National Center for Biotechnology Information (NCBI), increased numbers of these procedures are being done in the hospital worldwide, with increasing application of robot and tailored implant techniques. Ambulatory Surgery Centers (ASCs) are rapidly expanding their role in the market due to their cost-effectiveness and suitability for minimally invasive or same-day procedures. A study published in 2023 by the Journal of Arthroplasty reported that more than 60% of joint replacements in the United States are now being done on an outpatient basis. Specialty and rehabilitation centers, however, provide invaluable long-term recovery services, such as physical therapy and pain management particularly essential for older patients with chronic orthopedic disease thereby improving implant success and durability.

Role of Artificial Intelligence (AI) in Endoprosthesis Market

AI is playing an increasingly significant role in the development, customization, and implementation of endoprostheses, enhancing precision, patient outcomes, and efficiency in medical procedures. In June 2024, ECRI, a leading independent nonprofit focused on healthcare and patient safety, introduced an innovative AI-powered tool called SurgiSmartIQ. This tool provides healthcare providers with unparalleled insights into the utilization, clinical variation, and pricing of primary hip and knee implants used in joint procedures.

Global Endoprosthesis Market Regional Insights

Endoprosthesis Market Regional Insights

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North America Endoprosthesis Market Analysis and Trends

North America is dominating the endoprosthesis market, it holds approximately 40.2% of the global market share in 2025. The leading position is a result of combination of factors, including robust healthcare facilities and infrastructure- it comprises of well-equipped hospitals, clinics, and specialized facilities for joint replacement surgeries. The U.S. healthcare system focuses on both public and private insurance with a emphasis on specialized care and technological advancements. The North America population also has a high rate of joint disease. The most commonly found joint disease in America is Osteoarthritis, affecting over 30 million people which is costing approximately USD 185 billion every year.

Europe Endoprosthesis Market Trends

Europe accounts for over 30.3% of the global endoprosthesis market share. The region's growth is primarily driven by aging population. In January 2024, the European Union population was estimated as 449.3 million people, and among them 1/5 (21.6%) of it is aged people of 65 years and above, says the European Commission. These aged population has a high prevalence of osteoarthritis which requires joint replacement surgery. Besides that, Europe is house of advanced medical technology, which is leading in its country, Germany. It encompasses of industries over 35000 companies, primarily SMEs and employs over 800,000 people.

Asia Pacific Endoprosthesis Market Trends

Asia Pacific is the fastest-growing region in the endoprosthesis market, with a projected CAGR of 15.1%. This growth is fuelled by rising medical tourism in countries such as India, Thailand, and Malaysia, along with improved accessibility to orthopedic surgeries. India ranks on 10th position out of 46 top medical tourism destinations in the world, due to its affordable healthcare facilities and capabilities in specialised treatments. The region's aging population who are in great demand for joint replacement surgeries. within Asia Pacific region, China and India are observed to have an emerging economy which is leading to increase healthcare spendings and focus greatly on health issues such as osteoarthritis. According to National Health Institute, China is expected to have over 12 million osteoarthritis incidence case in 2039.

Latin America Endoprosthesis Market Trends

Latin America is experiencing steady growth in the endoprosthesis market, supported by increasing healthcare investments and awareness about advanced medical treatments. Brazil, in particular, is expected to register significant growth, driven by the rising demand for transcatheter devices and structural heart interventions. ​

Middle East & Africa Endoprosthesis Market Trends

The Middle East & Africa region is poised for growth in the endoprosthesis market, attributed to improving healthcare infrastructure and increasing awareness of advanced medical procedures. Countries like the UAE and South Africa are investing in healthcare advancements, leading to a gradual rise in the adoption of endoprosthetic treatments.

United States Endoprosthesis Market Trends

The U.S. has a rapidly aging population, which significantly increases the demand for joint replacement surgeries such as hip, knee, and shoulder replacements. As people age, the risk of degenerative joint diseases like osteoarthritis increases, leading to a higher need for endoprosthesis solutions. According to the U.S. Census Bureau, by 2030, all Baby Boomers (those born between 1946 and 1964) will be older than 65, representing about 21% of the total U.S. population. This will lead to a direct increase in the number of elderly individuals requiring joint replacement surgeries, particularly knee and hip replacements, which are the most common, further driving the market demand.

Germany Endoprosthesis Market Trends

Osteoarthritis, particularly in the knee and hip joints, is one of the leading causes of disability and is highly prevalent in Germany. The demand for joint replacement surgeries is directly linked to the increasing prevalence of OA among the population. The German Society for Orthopaedics and Trauma Surgery (DGOU) reports that nearly 20% of the German population suffers from osteoarthritis, especially in the elderly. As OA leads to joint pain and mobility issues, more patients seek joint replacements, making OA a critical driver of the endoprosthesis market.

Key Developments in Endoprosthesis Market

  • In January 2025, Gore launched of its Excluder conformable abdominal aortic aneurysm (AAA) endoprosthesis with the Active Control system in Canada.
  • In September 2024, THINK Surgical announced that its TMINI Miniature Robotic System received 510(k) clearance from the U.S. FDA for use with Zimmer Biomet's Persona® The Personalized Knee System. This clearance allows for an exclusive version of the TMINI System to be used with the Persona Knee System, offering surgeons both implant-exclusive and open-platform options for total knee arthroplasty.
  • In November 2024, Bentley announced the successful first human implantation of its newly CE-certified BeFlared stent graft system, designed for bridging in fenestrated endovascular aneurysm repair (FEVAR).
  • In June 2024, Zimmer Biomet entered into a limited exclusive distribution agreement with THINK Surgical to offer the TMINI® Miniature Handheld Robotic System for total knee arthroplasty. This partnership aims to integrate Zimmer Biomet technology into a customized TMINI robotic solution, complementing the company's ROSA® Robotics portfolio and providing surgeons with more options for robotic-assisted knee surgeries.
  • In September 2021, Boston Scientific, innovative medical device solutions acquired Devoro Medical, developer of the Wolf thrombectomy platform, to expand its electrophysiology and structural heart product portfolio with the WOLF thrombectomy platform.
  • In September 2022, Zimmer Biomet, a medical technology partnered with Surgical Planning Associates to integrate personalized 3D printing technology for joint replacement surgeries. This integration aims to improve patient outcomes.
  • In January 2022, Smith & Nephew, medical technology company acquired Engage Surgical, owner of the only cementless noncompartmental (partial) knee system commercially available in the U.S. to expand digital surgery capabilities by integrating Engage’s visualization technology in arthroscopic joint repair procedures.

Global Endoprosthesis Market Drivers:

Increasing Prevalence Of Cardiovascular Diseases

The rising prevalence of cardiovascular diseases such as coronary artery disease and heart valve diseases is driving the demand for endoprosthesis like stents, pacemakers, and heart valves. According to World Health Organization (WHO), 2021, cardiovascular diseases are the leading cause of death and it accounts for nearly 18 million deaths annually.

Global Endoprosthesis Market Opportunities- Growing medical tourism in emerging economies

The expanding medical tourism industry driven by the availability of high-quality and affordable treatments, is expected to provide lucrative opportunities for endoprosthesis market growth in emerging economies like India, Malaysia and Mexico.

Global Endoprosthesis Market Restraints:

  • High cost of endoprosthesis implants: The high cost of endoprosthesis implants like cardiac stents and knee implants is a major factor hampering market growth, especially in developing regions.
  • Unfavorable reimbursement policies: Stringent reimbursement scenarios for expensive endoprosthesis implants in some countries hamper the adoption rate. This impacts overall market growth.
  • Post-surgery complications: Complications like implant rejection, implant failure, infections, etc. associated with endoprosthesis implant procedures can restrain patients from undergoing such treatments.

Market Report Scope

Endoprosthesis Market Report Coverage

Report Coverage Details
Base Year: 2024 Market Size in 2025: USD 26.35 Bn
Historical Data for: 2020 To 2024 Forecast Period: 2025 To 2032
Forecast Period 2025 to 2032 CAGR: 7.5% 2032 Value Projection: USD 43.72 Bn
Geographies covered:
  • North America: U.S. and Canada
  • Latin America: Brazil, Argentina, Mexico, and Rest of Latin America
  • Europe: Germany, U.K., Spain, France, Italy, Russia, and Rest of Europe
  • Asia Pacific: China, India, Japan, Australia, South Korea, ASEAN, and Rest of Asia Pacific
  • Middle East: GCC Countries, Israel, and Rest of Middle East
  • Africa: South Africa, North Africa, and Central Africa
Segments covered:
  • By Product Type:  Knee Reconstruction, Hip Reconstruction, Extremities Reconstruction, Dental Reconstruction, Cardiac Reconstruction and Others (Spinal implant,Craniofacial reconstruction plates and bone grafts)
  • By Material: Metallic, Polymeric, Ceramic, Biological and Others (Bioresorbable materials, Composite materials)
  • By End-User: Hospitals, Orthopedic Clinics, Ambulatory Surgery Centers and Others (Specialty Clinics, Rehab Centers)
Companies covered:

Medtronic, Boston Scientific, Abbott Laboratories, Edwards Lifesciences, Johnson & Johnson, Stryker, Zimmer Biomet, Smith & Nephew, BD, Teleflex

Growth Drivers:
  • Increasing prevalence of cardiovascular diseases
  • Growth in geriatric population
  • Technological advancements
  • Favorable reimbursement policies
Restraints & Challenges:
  • High cost of endoprosthesis implants
  • Unfavorable reimbursement policies
  • Post-surgery complications

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Analyst Opinion (Expert Opinion)

  • The global endoprosthesis market will witness steady growth during the following five years. The growing geriatric population with an increased vulnerability to orthopedic diseases and injury will drive demand for various endoprosthesis products. However, the high cost involved in using highly advanced devices will restrain the market to a certain extent. Hip replacement and knee replacement command the largest share at present. Ex-Japan Asia Pacific will experience the highest market growth due to growing health care spending as well as improved medical tourism opportunities in India, Thailand, and other nations. The World Population Ageing Report by the United Nations (2022) reported that the worldwide population of ages 65 years and older are expected to reach double the previous total by the year 2050, highly boosting demand for joint replacement as well as orthopedic devices. This population shift, along with growing investments in the region's healthcare infrastructure, is making the market conditions supportive for growth in the region.
  • The development of bioresorbable implants composed of polylactic acid, which degrades after healing, is becoming increasingly prominent. These implants provide specific benefits in pediatric and temporary fixation situations, avoiding the necessity for removal surgeries. The increasing demand for minimally invasive surgical procedures to minimize complications and recovery time is a positive sign for the market. Moreover, supportive reimbursement policies for joint replacements in key developed economies drive patients to take advantage of these procedures. Governments in countries such as Germany and the U.S. have adopted policy reforms that offer strong support for elective orthopedic procedures. Ongoing research in additive layer production of implants with embedded drugs is also creating new possibilities. According to new research in Nature Biomedical Engineering (2024), multifunctional bioresorbable implants are being designed to deliver localized antibiotics or anti-inflammatory drugs, speeding post-surgical recovery and reducing infection rates.

Market Segmentation:

  • By Product Type:
    • Knee Reconstruction
    • Hip Reconstruction
    • Extremities Reconstruction
    • Dental Reconstruction
    • Cardiac Reconstruction
    • Others (Spinal implant, Craniofacial reconstruction plates and bone grafts)
  • By Material:
    • Metallic
    • Polymeric
    • Ceramic
    • Biological
    • Others (Bioresorbable materials, Composite materials)
  • By End-User:
    • Hospitals
    • Orthopedic Clinics
    • Ambulatory Surgery Centers
    • Others (Specialty Clinics, Rehab Centers)
  • By Region:
    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East
    • Africa

Sources

Primary Research Interviews from the following stakeholders:

Stakeholders:

  • Interviews with orthopedic surgeons, cardiovascular specialists, biomedical engineers, hospital administrators, and implant manufacturers.

Databases:

  • PubMed
  • ClinicalTrials.gov
  • HealthData.gov
  • OECD Health Statistics
  • WHO Global Health Observatory

Magazines:

  • MedTech Insight
  • Healthcare Technology News
  • Orthopedic Design & Technology (ODT)
  • Medical Device and Diagnostic Industry (MD+DI)

Journals:

  • Journal of Orthopaedic Research
  • Journal of Bone and Joint Surgery
  • Journal of Cardiovascular Interventions
  • Journal of Biomedical Materials Research

Newspapers:

  • The New York Times
  • The Guardian
  • The Wall Street Journal
  • Financial Times
  • Washington Post

Associations:

  • American Academy of Orthopaedic Surgeons (AAOS)
  • European Society of Cardiology (ESC)
  • Medical Device Manufacturers Association (MDMA)
  • International Society for Orthopaedic Surgery and Traumatology (SICOT)

Public Domain Sources:

  • World Health Organization (WHO)
  • Centers for Disease Control and Prevention (CDC)
  • U.S. Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • United Nations Population Division

Proprietary Elements:

  • CMI Data Analytics Tool, and Proprietary CMI Existing Repository of information for last 8 years

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About Author

Komal Dighe is a Management Consultant with over 8 years of experience in market research and consulting. She excels in managing and delivering high-quality insights and solutions in Health-tech Consulting reports. Her expertise encompasses conducting both primary and secondary research, effectively addressing client requirements, and excelling in market estimation and forecast. Her comprehensive approach ensures that clients receive thorough and accurate analyses, enabling them to make informed decisions and capitalize on market opportunities.

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Frequently Asked Questions

The Endoprosthesis Market is estimated to be valued at USD 26.35 Bn in 2025, and is expected to reach USD 43.72 Bn by 2032.

The CAGR of the Endoprosthesis Market is projected to be 7.5% from 2025 to 2032.

The major factors driving the growth of the market are rising prevalence of cardiovascular diseases and osteoporosis, growth in geriatric population, technological advancements in endoprosthesis implants, rising demand for minimally invasive surgeries, and favorable reimbursement policies and healthcare reforms.

The leading product type segment in the market is the knee reconstruction segment.

The major players operating in the market are Medtronic, Boston Scientific, Abbott Laboratories, Edwards Lifesciences, Johnson & Johnson, Stryker, Zimmer Biomet, Smith & Nephew, BD, and Teleflex.

North America is expected to lead the market owing to its high prevalence of target diseases, developed healthcare infrastructure, presence of key players, and favorable reimbursement scenarios.
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