Industrial Microbiology–Solving Big Issues with Micro Size/Microbial Revolution
Industrial Microbiology involves commercial use of micro-organisms in various industrial processes such as fermentation. Use of micro-organisms for production processes has been in use since 18th century and was facilitated by discovery of various microorganisms over the years. Depending on nature of process, the industrial microbiology has two aspects, namely production of microbial products through fermentation processes and use of microorganisms for services, such as pollution control, to curb the contamination, and waste treatment. Microbial products produced using microbiology include bread, beer, cheese, enzymes, energy sources, food ingredients, and pharmaceuticals. Pharmaceutical industries require sterile environments, especially, injectable manufacturing plants as injectable products interfere directly with the circulatory system, where microbiology plays an important role. Second aspect of the industrial microbiology is employed for pollution control and restricting and creating microbial free environment. Micro-organisms can degrade all natural and man-made products making it easy to create pollution and contamination free environment. Products manufactured using microbiology include food, beverages, food additives and supplements, antibiotics, microbial enzymes, industrial chemical, and fuels.
Increasing microbiology applications for a range of industrial and healthcare issues is expected to boost the use of micro-organisms for industrial purposes
Quality control in pharmaceutical and food industry is of paramount importance, as healthcare is directly associated with the products from these industries. Microbial contamination in injectable, eye drops, drugs, nasal solutions, and food industries can be prevented with the help of micro-organisms by using various tests such as bio burden and growth promotion tests. According to the World Health Organization (WHO), unsafe food contaminated with harmful bacteria, parasites, and viruses can cause more than 200 diseases from diarrhea to cancers. Furthermore, food contamination has cost around 33 Mn of healthy life years according to the WHO. Microorganisms offer properties, such as rapid multiplication and growth rate, biodiversity, great shelf life, and use of byproducts after microbial process is finished, which saves time and cost for various industries. The field has advanced over years with inventions, such as microscope and increasing knowledge about microbial genetic makeup and biological processes associated with microorganisms. The technological advancements have made it possible to harness this knowledge into industrial microbiology. Application of microorganisms in bioremediation is expected to boost the growth of industrial microbiology market. Bioremediation is an important sector, which uses microorganisms to neutralize pollutants from a contaminated site. Industrial contamination is an ever growing issue where bioremediation has proven to be effective. The companies providing industrial microbiology solutions offer various products and services, such as quality control tests, equipment’s and systems, biomass conversion products for bioremediation, reaction consumables, and laboratory equipment.
The global industrial microbiology market was valued at US$ 8,678.2 million in 2016 and is expected to witness a robust CAGR of 7.2% over the forecast period (2017 - 2025).
Figure 1. Global Industrial Microbiology Market by Region 2016 (US$ Mn)
Advent of technology and improved understanding of micro-organisms functions and benefits is expected to increase their applications
Advances in fields of Recombinant DNA technology, use of microorganisms in treating diseases, rising prevalence of various bacterial, and viral infections globally is expected to boost the growth of industrial microbiology market with respect to pharmaceutical industry. Use of microorganisms in manufacturing various improvised vaccines for existing as well new infectious diseases is supporting the market growth. Cosmetic industry is growing, owing to the factors, such as evolving lifestyles, increasing demand for aesthetic life fulfilled by various offerings from the industry such as color cosmetics and skin care. Furthermore, in cosmetic industry, raw materials need to be thoroughly tested for any microbial contamination before further processing according to the Food & Drug Administration (FDA). These factors are expected to further propel the use of microbiological testing for cosmetic product safety. Diabetes, a potential life-threatening disease with no cure available, was affecting 30.3 Mn people in the U.S. out if which 1.25 Mn were suffering from type 1 diabetes in 2015 according to American Diabetes Association. Insulin is manufactured by using Recombinant DNA technology, which is a necessity for type 1 diabetes patients and with advances in the technology such as artificial chromosomes, automated DNA sequencing, and the use of microbiology in this area is expected to support the market growth over the forecast period.
Some major players operating in the industrial microbiology market include Merck KGaA, bioMérieux SA, Thermo Fisher Scientific Inc., Eppendorf AG, Bruker, Sartorius AG, QIAGEN, Becton Dickinson and Company, Bio-Rad Laboratories Inc., and Mettler-Toledo International Inc.
Applied Microbiology involves use of microorganisms in various industries, such as pharmaceutical and biotechnology industry, cosmetic industry, food and beverages industry, agriculture and environment, and many others. The use of advanced technology and knowledge about microorganisms in healthcare and environmental issues is of prime importance. In case of pharmaceutical industry the products manufactured using microbiology include amino acids, organic acids, vitamins, nucleotides, antibiotics, insulin and other hormones, polysaccharides, bio surfactants, and hormones. Pharmaceutical microbiological safety, food microbiological safety, cosmetics microbiological safety and contamination control can be assured with the application of microbiology. Application of microorganisms is beneficial as maximum yield of a product can be obtained with the help of customization of the microorganism species such as exposing them to mutagens or by gene amplification. Biomass conversion is another area wherein microorganisms are employed in various processes such as anaerobic digestion, fermentation, pyrolysis, and gasification.
Some of the lucrative areas for application of microbiology include bioremediation, bio-fuels production, genetic engineering, green chemistry, and metabolic engineering over the forecast period. Natural fuel consumption has increased exponentially over the past few years, owing to lifestyle changes, increased number of vehicles, and natural fuel resources, which are depleting at faster rates. Wherein bio-fuels can be a remedy. Genetically modified food products can also be an effective remedy against malnutrition in emerging economies such as Africa. Microorganisms are used in biotechnology field, especially in Recombinant DNA technology for various applications, such as crop agriculture, gene therapy, pharmaceutics, vaccine design and bioremediation, and further advancement in the respective areas is expected to boost the market growth over the forecast period. Global immunization coverage is expected to increase, owing to joint efforts by economies and the World Health Organization (WHO), such as Global Vaccine Action Plan, World Immunization Week, and creating a robust demand for advanced vaccines.
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